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4篇 您的检索式:作者名="Alexander Beham"
    题名 作者 年代 出处 被引量
1Gastrointestinal stromal tumors显示文摘Alexander Beham Inga-Marie Schaefer Philipp Schüler Silke Cameron B. Michael Ghadimi 2012International Journal of Colorectal Disease2012,,6:1
2Patients without hepatocellular carcinoma progression after transarterial chemoembolization benefit from liver transplantation显示文摘AIM: To assess the outcome of patients, who under-went transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) and subsequently liver transplantation (OLT) irrespective of tumor size when no tumor progression was observed.METHODS: Records, imaging studies and pathology of 84 patients with HCC were reviewed. Ten patients were not treated at all, 67 patients had TACE and 35 of them were listed for OLT. Tumor progression was monitored by ultrasound and AFP level every 6 wk. Fifteen patients showed signs of tumor progression without transplantation. The remaining 20 patients underwent OLT. Further records of 7 patients with HCC seen in histological examination after OLT were included.RESULTS: The patients after TACE without tumor progression underwent transplantation and had a median survival of 92.3 mo. Patients, who did not qualify for liver transplantation or had signs of tumor progression had a median survival of 8.4 mo. The patients without treatment had a median survival of 3.8 mo. Independent of International Union Against Cancer (UICC) stages, the patients without tumor progression and subsequent OLT had longer median survival. No significant difference was seen in the OLT treated patients if they did not fulfill the Milan criteria.CONCLUSION: Selection of patients for OLT based on tumor progression results in good survival. The evaluation of HCC patients should not only be based on tumor size and number of foci but also on tumor progression and growth behavior under therapy.Aiman Obed Alexander Beham Kerstin Püllmann Heinz Becker Hans J Schlitt Thomas Lorf 2007World Journal of Gastroenterology2007,13,5:1
3Gastrointestinal stromal tumors显示文摘Alexander W. Beham Inga-Marie Schaefer Philipp Schüler Silke Cameron B. Michael Ghadimi 2012International Journal of Colorectal Disease2012,,6:1
45-Fluorouracil-related enhancement of adenoviral infection is Coxsackievirus-adenovirus receptor independent and associated with morphological changes in lipid membranes显示文摘瞄准:评估在 adenoviral 感染上位于 5 氟尿嘧啶(5-FU ) 的效果下面的机制。方法:表示人的结肠癌房间线的低、高的 Coxsackievirus 侵入人体气管粘膜的病菌受体(汽车) 与 5-FU 和二删除 E1 的 adenoviral 构造被对待,一转 GFP (Ad/CMV-GFP ) 另外的 bax (Ad/CEA-bax ) 。感染的房间的数字被 GFP 表示监视。为了在受体评估 5-FU 的效果,释放系统, Ad/GFP 在 lipo 被包含一些并且与 5-FU 对待。Ad/GFP 版本与上层清液与 293 个房间的 PCR 和感染被估计。建筑群被使调查词法的 Ad5-GFP-liposome 的电子显微镜学在 5-FU 以后 lipo 改变一些。结果:所有房间线的感染率与新兴的 5-FU 集中从 50% ~ 98% 增加了。提高的病毒的举起独立于 CAR 表示。另外, 5-FU 对待一些释放了的 lipo 2-2.5 时间更多的侵入人体气管粘膜的病菌。而且, 5-FU-treated lipo 一些显得不规则并且象多孔一样。结论:不管汽车, Adenoviral 举起面对 5-FU 被提高并且在做两个的联合的膜与词法变化被联系在基因治疗的一种有希望的选择。Chiara Cabrele Mandy Vogel Pompiliu Piso Markus Rentsch Josef Schroder Karl W Jauch Hans J Schlitt Alexander Beham 2006World Journal of Gastroenterology2006,12,32:0
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