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| 1 | Transabdominal Surgical Approach in the Management of Renal Tumors Involving the Retrohepatic Inferior Vena Cava显示文摘 | Jose A. Gonzalez-Fajardo Ernesto Fernandez Jesús Rivera Alejandro Pelaz Javier Gonzalez-Zarate Juan C. Alvarez E. González C. Vaquero | 2000 | Annals of Vascular Surgery2000，，5： | 2 |
| 2 | Predictors of Nonalcoholic Steatohepatitis (NASH) in Obese Patients Undergoing Gastric Bypass显示文摘 | Camilo Boza MD Arnoldo Riquelme MD Luis Iba?ez MD Ignacio Duarte MD Enrique Norero MD Paola Viviani MD Alejandro Soza MD Jose Ignacio Fernandez MD Alejandro Raddatz MD Sergio Guzman MD Marco Arrese MD | 2005 | Obesity Surgery2005，，8： | 1 |
| 3 | Survival curve and factors related to drainage during the first 24?h after total knee arthroplasty显示文摘 | Oscar Ares-Rodriguez Alejandro Hernadez Martinez Alberto Hernandez Fernandez Enric Castellet Antonio Navarro Quilis | 2008 | Knee Surgery Sports Traumatology Arthroscopy2008，，6： | 1 |
| 4 | Morphometry and subpopulation structure of Holstein bull spermatozoa: variations in ejaculates and cryopreservation straws显示文摘精子质量在人工的繁殖节目为精子剂量的计算被评估。使用的最普通的参数是活动性,但是形态学作为基因质量的一个预言者有一个更高的潜力。从 CASA-Morph 技术的 Morphometry 计算改进词法评估并且允许数学途径到这个问题。从 28 头荷兰的一种乳牛公牛的精液被人工的阴道收集,并且几精液被学习。在一般评估以后,样品被冲淡,在 0.25 根 ml 稻草包装了,并且在液体存储了氮。二根稻草与 Diff-Quik 每样品被融化,并且幻灯片被处理并且染色。样品被一个 CASA-Morph 系统为八个 morphometric 参数分析。除了 “ classical”统计途径基于变化分析(动物,精液,和稻草之间的揭示差别) ,主要部件(PC ) 分析证明变量被组织进 PC1 与尺寸有关,并且塑造的 PC2。也就是, Subpopulation 结构分析给四个组看了从他们的主导的特征大、小、短、狭窄,分别地代表 31.0% , 27.3% , 24.1% ,和 17.7% 全部的人口。分布在动物和精液之间,但是在稻草之间变化了,在仅仅四个动物没有差别。认为划分了成 subpopulations 的一张精液精子人口是思考可以计量的参数的这条现代途径由 CASA-Morph 系统技术产生了在精子上打开一个新看法函数。这是使用这条途径从一样的个人评估不同精液和稻草的第一研究。更多的工作必须被做在帮助繁殖程序改进精液的剂量计算。 | Anthony Valverde Hector Arenan Maria Sancho Jesus Contell Jesus Yaniz Alejandro Fernandez Caries Soler | 2016 | Asian Journal of Andrology2016，18，6： | 1 |
| 5 | Predictors of Nonalcoholic Steatohepatitis (NASH) in Obese Patients Undergoing Gastric Bypass显示文摘 | Camilo Boza MD Arnoldo Riquelme MD Luis Iba?ez MD Ignacio Duarte MD Enrique Norero MD Paola Viviani MD Alejandro Soza MD Jose Ignacio Fernandez MD Alejandro Raddatz MD Sergio Guzman MD Marco Arrese MD | 2005 | Obesity Surgery2005，，8： | 1 |
| 6 | Sedative and sleep enhancing properties of linarin,a flavonoid-isolated from Valeriana officinalis显示文摘 | Sebastian Fernandez Cristina Wasowski Alejandro C Paladini | 2004 | Pharmacol Biochem Behav2004，77，2： | 1 |
| 7 | Syner- gistic interaction between hesperidin, a natural flavonoid, and diazepam 显示文摘 | Fernandez Sebastion P Wasowski Cristina Paladini Alejandro C | 2005 | European Journal of Pharmaenlogy2005，512，23： | 1 |
| 8 | Depressive severity associated with cesarean section in young depressed individuals显示文摘This cross-sectional study recruited consecutively 347 patients (178 males,169 females) aged 19 to 30 years with a diagnosis of MDD according to Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition (DSM-V) criteria who underwent in-person interviews,the mini international neuropsychiatric interview,and physical examinations by experienced psychiatrists at Division of Neuropsychiatry,Department of Neurology,Xuanwu Hospital of Capital Medical University (Beijing,China) between August 20,2015,and December 28,2018.All patients were excluded with anemia,thyroid dysfunction,mental retardation,neurologic conditions,bipolar disorders,schizophrenia,and other mental disorders.Depressive symptoms were assessed with the Hamilton rating scale for depression (HAMD-17) by three experienced psychological testing technicians who were blinded to all subjects' birth delivery types at the Neuropsychological Center of Department of Neurology of Xuanwu Hospital.The study was conducted in accordance with the Declaration of Helsinki and was approved by the Ethics Committee of Xuanwu Hospital.As a retrospective study and data analysis were performed anonymously,this study was exempt from the informed consent from patients. | Xiao-Tong Yang Wen-Rui Zhang Zi-Chen Tian Kun Wang Wei-Jun Ding Yuan Liu Chun-Xiu Wang Hai-Xia Leng Mao Peng Wen-Feng Zhao Jia-Yi Li Lei Yang Xing-Yue Zhang Lei Wu Jun-Hui Wang Alejandro Fernandez Tian-Mei Si Liu-Hui Fu Jean-Eric Ghia Hui-Qing Dong Yu-Ping Wang Hong-Xing Wang | 2019 | Chinese Medical Journal2019，，15： | 1 |
| 9 | Low- fi'equency absorption using a two-layer system with active control of input impedance显示文摘 | PEDRO COBO ALEJANDRO FERNANDEZ | 2003 | JASA2003，114，6： | 1 |
| 10 | From'planning in section'to'semiduplex':The New Humanism and the alternate-corridor technique显示文摘Most of the pretending innovative modern housing projects show a common element that can be perceived when looking at the cross-section,evidencing the use of alternate corridors,which was recognized as a projective technique under Wells Coates expression'Planning in Section'.Contrasting virtues concerning the resulting space were observed at different historical moments.The late 19th Century used it to create privacy.The modern architecture used it to increase efficiency,where flexibility was included.However,during the’60s,the alternative corridor technique started to be used to attend social issues,popularizing the split-level term,and echoing 19th Century privacy interests.Keywords like Smithson’s'doorstep'and Candilis'semi-duplex'section reveal their approaches.Well-differentiated areas(public/intimate/col-lective)and socially controlled areas were obtained in domestic interiors with a few steps,creating singular spaces where children can play while being monitored by adults.Semi-duplex geometry showed new adaptability to different profiles:a small kitchenless apartment for a bachelor could be inserted aside from a larger two-level family apartment.This paper shows an overview of this projective technique by contrasting different housing projects.Since similar split-level geometries seem to have been coming back recently,questions about it are necessary. | Alejandro Perez-Duarte Fernandez Jose Manuel Falcon Meraz | 2020 | Frontiers of Architectural Research2020，9，3： | 0 |
| 11 | Minimizing sperm oxidative stress using nanotechnology for breeding programs in rams显示文摘Background Artificial insemination(AI)is a routine breeding technology in animal reproduction.Nevertheless,the temperature-sensitive nature and short fertile lifespan of ram sperm samples hamper its use in AI.In this sense,nanotechnology is an interesting tool to improve sperm protection due to the development of nanomaterials for AI,which could be used as delivery vehicles.In this work,we explored the feasibility of vitamin E nanoemulsion(NE)for improving sperm quality during transport.Results With the aim of evaluating this proposal,ejaculates of 7 mature rams of Manchega breed were collected by artificial vagina and extended to 60×10^(6)spz/mL in AndromedR.Samples containing control and NE(12 mmol/L)with and without exogenous oxidative stress(100μmol/L Fe2+/ascorbate)were stored at 22 and 15℃and motility(CASA),viability(YO-PRO/PI),acrosomal integrity(PNA-FITC/PI),mitochondrial membrane potential(Mitotracker Deep Red 633),lipoperoxidation(C11 BODIPY 581/591),intracellular reactive oxygen species(ROS)production and DNA status(SCSAR)monitored during 96 h.Our results show that NE could be used to maintain ram spermatozoa during transport at 15 and 22℃for up to 96 h,with no appreciable loss of kinematic and physiological characteristics of freshly collected samples.Conclusions The storage of ram spermatozoa in liquid form for 2-5 d with vitamin E nanoemulsions may lead more flexibility to breeders in AI programs.In view of the potential and high versatility of these nanodevices,further studies are being carried out to assess the proposed sperm preservation medium on fertility after artificial insemination. | Alejandro Jurado‑Campos Pedro Javier Soria‑Meneses Maria Arenas‑Moreira Carlos Alonso‑Moreno Virginia Rodriguez‑Robledo Ana Josefa Soler Jose Julian Garde Maria del Rocio Fernandez‑Santos | 2023 | Journal of Animal Science and Biotechnology2023，14，6： | 0 |
| 12 | Adding vortexing to the Maki technique provides no benefit for the diagnosis of catheter colonization or catheter-related bacteremia显示文摘BACKGROUND A previous study compared vortexing and Maki techniques for the diagnosis of catheter-related bloodstream infection(CRBSI),and concluded that vortexing was not superior to Maki method.AIM To determine whether the combined use of vortexing and Maki techniques provides profitability versus the Maki technique for the diagnosis of catheter tip colonization(CTC)and CRBSI.METHODS Observational and prospective study carried out in an Intensive Care Unit.Patients with suspected catheter-related infection(CRI)and with one central venous catheter for at least 7 days were included.The area under the curve(AUC)of the Maki technique,the vortexing technique and the combination of both techniques for the diagnosis of CTC and CRBSI were compared.RESULTS We included 136 episodes of suspected CRI.We found 21 cases of CTC of which 10 were also CRBSI cases.Of the 21 CTC episodes,18(85.7%)were diagnosed by Maki technique and vortexing technique,3(14.3%)only by the technique of Maki,and none only by technique of vortexing.Of the 10 CRBSI episodes,9(90.0%)were diagnosed by the techniques of Maki and vortexing,1(10.0%)was diagnosed only by the technique of Maki,and none only by the technique of vortexing.We no found differences in the comparison of AUC between the technique of Maki and the combination of Maki and vortexing techniques for the diagnosis of CTC(P=0.99)and CRBSI(P=0.99).CONCLUSION The novel finding of our study was that the combined use of vortexing and Maki techniques did not provide profitability to the technique of Maki alone to CRBSI diagnosis of. | Leonardo Lorente Maria Lecuona Fernandez Adriana González-Mesa Judith Oliveras-Roura Cristina Rosado Pablo Cabrera Emma Casal Alejandro Jiménez María Luisa Mora Ana Madueño | 2024 | World Journal of Critical Care Medicine2024，13，1： | 0 |
| 13 | A new oxidative pathway of nitric oxide production from oximes in plants显示文摘Nitric oxide(NO)is an essential reactive oxygen species and a signal molecule in plants.Although several studies have proposed the occurrence of oxidative NO production,only reductive routes for NO production,such as the nitrate(NO_(3)^(-))-upper-reductase pathway,have been evidenced to date in land plants.However,plants grown axenically with ammonium as the sole source of nitrogen exhibit contents of nitrite and NO3−,evidencing the existence of a metabolic pathway for oxidative production of NO.We hypothesized that oximes,such as indole-3-acetaldoxime(IAOx),a precursor to indole-3-acetic acid,are intermediate oxidation products in NO synthesis.We detected the production of NO from IAOx and other oximes catalyzed by peroxidase(POD)enzyme using both 4-amino-5-methylamino-2′,7′-difluorescein fluorescence and chemiluminescence.Flavins stimulated the reaction,while superoxide dismutase inhibited it.Interestingly,mouse NO synthase can also use IAOx to produce NO at a lower rate than POD.We provided a full mechanism for POD-dependent NO production from IAOx consistent with the experimental data and supported by density functional theory calculations.We showed that the addition of IAOx to extracts from Medicago truncatula increased the in vitro production of NO,while in vivo supplementation of IAOx and other oximes increased the number of lateral roots,as shown for NO donors,and a more than 10-fold increase in IAOx dehydratase expression.Furthermore,we found that in vivo supplementation of IAOx increased NO production in Arabidopsis thaliana wild-type plants,while prx33-34 mutant plants,defective in POD33-34,had reduced production.Our data show that the release of NO by IAOx,as well as its auxinic effect,explain the superroot phenotype.Collectively,our study reveals that plants produce NO utilizing diverse molecules such as oximes,POD,and flavins,which are widely distributed in the plant kingdom,thus introducing a long-awaited oxidative pathway to NO production in plants.This knowledge has essential implications for understanding signaling in biological systems. | Pedro Lopez-Gomez Javier Buezo Marina Urra Alfonso Cornejo Raquel Esteban Jorge Fernandez de los Reyes Estibaliz Urarte Estefania Rodriguez-Dobreva Alejandro Chamizo-Ampudia Alejandro Eguaras Sebastian Wolf Daniel Marino Victor Martinez-Merino Jose F.Moran | 2024 | Molecular Plant2024，17，1： | 0 |
| 14 | Prospective application of a bleeding and ischemic risks-adjusted antithrombotic protocol in elderly patients revascularized with everolimus-eluting stents:EPIC05-Sierra75 study显示文摘OBJECTIVES Elderly patients show a higher incidence of ischemic and bleeding events after percutaneous transluminal coron-ary intervention(PCI).We sought to investigate outcomes in elderly patients treated with antithrombotic strategy guided by bleeding and ischemic risks after revascularization with last generation everolimus-eluting stent(EES).METHODS Prospective multicenter registry including patients over 75 years revascularized with EES and antithrombotic ther-apy guided by clinical presentation,PCI complexity and PRECISE DAPT score.Co-primary safety endpoints were:(1)composite of cardiac death,myocardial infarction and stent thrombosis and;(2)bleeding(BARC 2-5).Primary efficacy endpoint was target lesion revascularization.A matched group of patients revascularized with current drug-eluting stents and no such tailored antith-rombotic therapy was used as control.RESULTS Finally,1064 patients were included in SIERRA-75 cohort,80.8±4.2 years,36.6%women,71%acute coronary syn-dromes(ACS)and 53.6%complex PCI.Co-primary safety endpoint of major adverse cardiovascular events was met in 6.2%,co-primary safety endpoint of bleeding in 7.8%and primary efficacy endpoint of TKLR in 1.5%.The multivariable adjusted model showed no significant association of the prescribed short/long dual antiplatelet therapy(DAPT)durations with any endpoint suggesting a well tailored therapy.No stent thrombosis reported in the subgroup with 1-3 months DAPT duration.As compared to control group,bleeding BARC 2-5 was significantly lower in SIERRA-75 group(7.4%vs.10.2%,P=0.04)as well as the net safety-efficacy endpoint(14.3%vs.18.5%,P=0.02).CONCLUSIONS In elderly population,the application of this risks-adjusted antithrombotic protocol after revascularization with last generation EES seems to be associated with an improved prognosis in terms of ischemic and bleeding outcomes. | Jose M de la Torre Hernandez Ramon Lopez Palop Jesus M Jimenez Mazuecos Pilar Carrillo Sáez Alejandro Gutierez-Barrios Eduardo Pinar Belen Cid Luis Fernandez Tamara Garcia Camarero Cristóbal Urbano-Carrillo Juan F Oteo Dominguez Victor A Jimenez Diaz Antonio EGomez Menchero Eladio Galindo Fernández Juan GCórdoba Soriano Raymundo Ocaranza Eduardo ArroyoÚcar Koldobika Garcia San Roman Silvio Leal Ginés Martínez Cáceres Jose A Linares Vicente Georgina Fuertes Ferre Xavier Carrillo Juan CRama Merchán Catia Costa Juan Sanchis Renato Fernandes Alberto Rodrigues Jose M Vegas Valle Hélder Pereira Armando Perez de Prado | 2022 | Journal of Geriatric Cardiology2022，19，5： | 0 |
| 15 | Recirculating chemohyperthermia as a treatment for non-muscle invasive bladder cancer:Current and future perspectives显示文摘About 75% of all bladder cancer diagnosed are non-muscle invasive bladder cancer(NMIBC), recurring over 50% of them after transurethral resection of the bladder tumor. In order to prevent recurrences, adjuvant intravesical chemotherapy with mitomycin C and immunotherapy with bacillus Calmette-Gu-érin(BCG) is traditionally used. Unfortunately, many patients relapse after receiving these treatments and a significant proportion of them require surgery. After a one-to-three years BCG maintenance, the risk for progression at 5 years was 19.3% for T1G3 tumors. Many new treatment approaches are being investigated to increase the effectiveness of adjuvant intravesical therapy. One of the developing treatments for intermediate and high-risk NMIBC is the combination of intravesical chemotherapy and hyperthermia, called chemohyperthermia. This article provides a review of the mechanism of action, current status and indications, results and future perspectives. | Javier Flores-Carbajal Alejandro Sousa-Escandón Daniel Sousa-Gonzalez Silvia Rodriguez Gomez Manuel Lopez Saavedra M Elia Fernandez Martinez | 2017 | World Journal of Clinical Urology2017，6，2： | 0 |
| 16 | Gastric inflammatory myofibroblastic tumor, a rare mesenchymalneoplasm: A case report显示文摘BACKGROUND The inflammatory myofibroblastic tumor(IMT)is a rare mesenquimal tumor of doubtful biological behaviour.It’s characterised for affecting mainly children and young adults,although it can appear at any age,being the lungs the primary affected organ(in children it represents 20%of all primary pulmonary tumors).CASE SUMMARY We present the case of a 45 year old woman,with a computed tomography(CT)finding of injury on the anterior surface of the fundus/gastric body and a solid perigastric injury of 12 mm in the ecoendoscopy.The case is presented in the tumor committee deciding to perform a laparoscopic wedge resection.The histological diagnosis was a IMT.The diagnosis is based on imaging tests like the abdominal CT,abdominal ecography and the ecoendoscopy but to confirm the diagnosis a pathological study is necessary.CONCLUSION Due to the unpredictable nature of this tumor,surgical resection is the best therapeutic option. | Manuel Fernandez Rodriguez Pedro Joaquin Artuñedo Pe Alejandro Callejas Diaz Gala Silvestre Egea Cristián Grillo Marín Eva Iglesias Garcia Jose Luis Lucena de La Poza | 2023 | World Journal of Gastrointestinal Surgery2023，15，11： | 0 |
| 17 | 提尔皮茨博物馆显示文摘新落成的提尔皮茨博物馆是沙漠中的一处庇佑所,它的存在就像是对曾经发生在丹麦西海岸的战争历史的一次平静的隔空对话。这座面积为2 800m^2的'隐形博物馆'开创性地将德国二战时期的战壕延伸转变为一个文化容器,其中的四个展厅,运用简单的结构体系无缝嵌入大地。初到这里,参观者首先将看到的是原有的战壕,直到他们穿过荒草丛生的小径,才会渐渐感知这些深深刻入沙丘的墙体. | David Zahle Andreas K.Pedersen Snorre Emanuel Nash J■rgensen Michael Andersen Hugo Soo Marcella Martinez Geoffrey Eberle Adam Busko Hanna Johansson Jakob Andreassen Charlotte Cocco Mikkel Marcker Stubgaard Michael Sch■nemann Jensen Alejandro Mata Gonzales Kyle Thomas David Tousant Jesper Boye Andersen Alberte Danvig Jan Magasanik Enea Michelesio Alina Tamosiunaite Ryohei Koike Brigitta Gulyás Katarzyna Krystyna Siedlecka Andrea Scalco Tobias Hjortdal Maria Teresa Fernandez Rojo Rasmus Hjortshoj 运小红(译) | 2019 | 城市环境设计2019，0，2： | 0 |
| 18 | Influence of Induction Motor Design Data on Effects of Cage Asymmetry显示文摘 | Alejandro Fernandez Gomez Tadeusz J. Sobczyk | 2013 | Journal of Energy and Power Engineering2013，7，8： | 0 |
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