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| 1 | Hepatic ischemic preconditioning increases portal vein flow in experimental liver ischemia reperfusion injury显示文摘BACKGROUND: Ischemic preconditioning(IPC) has been shown to decrease liver injury and to increase hepatic microvascular perfusion after liver ischemia reperfusion. This study aimed to evaluate the effects of IPC on hemodynamics of the portal venous system. METHODS: Thirty-two rats were randomized into two groups: IPC group and control group. The rats of the IPC group underwent IPC by 10 minutes of liver ischemia followed by 10 minutes of reperfusion before liver ischemia, and the rats of the control group were subjected to 60 minutes of partial liver ischemia. Non-ischemic lobes were resected immediately after reperfusion. The animals were studied at 4 hours and 12 hours after reperfusion. Mean arterial pressure, heart rate, portal vein flow and pressure were analyzed. Blood was collected for the determination of the levels of aspartate aminotransferase, alanine aminotransferase, calcium, lactate, pH, bicarbonate, and base excess. RESULTS: IPC increased the mean portal vein flow at 4 hours and 12 hours after reperfusion. IPC recovered 78% of the meanportal vein flow at 12 hours after reperfusion. IPC decreased the levels of aspartate aminotransferase, alanine aminotransferase and lactate, and increased the levels of ionized calcium, bicarbonate and base excess at 12 hours after reperfusion. CONCLUSIONS: This study demonstrated that IPC increases portal vein flow and enhances hepatoprotective effects in liver ischemia reperfusion. The better recovery of portal vein flow after IPC may be correlated with the lower levels of transaminases and with the better metabolic profile. | Estela RR Figueira Joel A Rocha-Filho Mauro Nakatani Marcelo FS Buto Eduardo R Tatebe Vitor O Andre Ivan Cecconello Luiz AC D'Albuquerque | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，1： | 6 |
| 2 | Pentoxifylline enhances the protective effects of hypertonic saline solution on liver ischemia reperfusion injury through inhibition of oxidative stress显示文摘BACKGROUND:Liver ischemia reperfusion(IR)injury triggers a systemic inflammatory response and is the main cause of organ dysfunction and adverse postoperative outcomes after liver surgery.Pentoxifylline(PTX)and hypertonic saline solution(HTS)have been identified to have beneficial effects against IR injury.This study aimed to investigate if the addition of PTX to HTS is superior to HTS alone for the prevention of liver IR injury. | Vinicius Rocha-Santos Estela RR Figueira Joel A Rocha-Filho Ana MM Coelho Rafael Soraes Pinheiro Telesforo Bacchella Marcel CC Machado Luiz AC D'Albuquerque | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，2： | 3 |
| 3 | Early maternal age at first birth is associated with chronic diseases and poor physical performance in older age:cross-sectional analysis from the International Mobility in Aging Study显示文摘 | Pirkle CM de Albuquerque Sousa AC Alvarado B | 2014 | BMC Public Health2014，，14： | 1 |
| 4 | Successful liver allograft inflow reconstruction with the right gastroepiploic vein显示文摘Portal vein thrombosis is a common complication in cirrhotic patients. When portal vein thrombectomy is not a suitable option, a large collateral vessel can be used for allograft venous inflow reconstruction. We describe an unusual case of successful portal revascularization using the right gastroepiploic vein. The patient underwent a cadaveric orthotopic liver transplantation with end-to-end anastomosis of the portal vein to the right gastroepiploic vein. Six months after liver transplantation the patient is well with good liver function. The use of the right gastroepiploic vein for allograft venous reconstruction is feasible and safe, with a great advantage of avoiding the need of venous jump graft. | Rafael S Pinheiro Ruy J Cruz Jr Lucas S Nacif Matheus F Vane Luiz AC D'Albuquerque | 2016 | Hepatobiliary & Pancreatic Diseases International2016，15，1： | 1 |
| 5 | Resection of liver metastases from a noneoloreetal primary: Indication and results based on 147 monoeentrie patients 显示文摘 | Elias D Albuquerque AC EggenspielerP etal | 1998 | J Am Coll Surg1998，187，5： | 1 |
| 6 | Determina- tion of the cut-off value of serum alanine aminotrans ferase in patients undergoing hemodialysis, to identi- fy biochemical activity in patients with hepatitis C viremia显示文摘 | Lopes EP Gouveia EC Albuquerque AC | 2006 | J Clin Virol2006，35，3： | 1 |
| 7 | Predicting risk of atrial fibrillation after heart value surgery evaluation of a Brazilian risk score显示文摘 | Sá MP Sá MV Albuquerque AC | | 0，，01： | 1 |
| 8 | Postoperative chylous ascites: a rare complicationof laparoscopic Nissen fundoplication 显示文摘 | Bacelar TS de Albuquerque AC de Arruda PC | 2003 | JSLS2003，7，3： | 1 |
| 9 | Seroprevalence and factors associated with human immunodeficiency virus (HIV) and syphilis in inmates in the state of Pernambuco, Brazil 显示文摘 | Albuquerque AC Silva DM Rabelo DC | 2014 | Cien Saude Colet2014，19，7： | 1 |
| 10 | Chest radiographic findings in patients HIV/AIDS and pulmonary tuberculosis显示文摘 | Albuquerque YM Lima AL Silva AC | 2013 | Int J STD AIDS2013，24，12： | 1 |
| 11 | Decompressive craniectomy for treatment of intracranial hypertension secondary to large ischemic cerebral infarction:analysis of 34 cases显示文摘 | Nobre MC Monteiro M Albuquerque AC | 2007 | Arq Neuropsiquiatr2007，65，1： | 1 |
| 12 | Does bilioenteric anastomosis impair results of liver resection in primary intrahepatic lithiasis?显示文摘AIM:To evaluate the long-term results of liver resection for the treatment of primary intrahepatic lithiasis.Prognostic factors,especially the impact of bilioenteric anastomosis on recurrence of symptoms were assessed.METHODS:Forty one patients with intrahepatic stones and parenchyma fibrosis/atrophy and/or biliary stenosis were submitted to liver resection.Resection was associated with a Roux-en-Y hepaticojejunostomy in all patients with bilateral stones and in those with unilateral disease and dilation of the extrahepatic biliary duct(>2 cm).Late results and risk factors for recurrence of symptoms or stones were evaluated.RESULTS:There was no operative mortality.After a mean follow-up of 50.3 mo,good late results were observed in 82.9% of patients;all patients submitted to liver resection alone and 58.8% of those submitted to liver resection and hepaticojejunostomy were free of symptoms(P=0.0006).Patients with unilateral and bilateral disease showed good late results in 94.1% and 28.6%,respectively(P<0.001).CONCLUSION:Recurrence of symptoms in patients with hepaticojejunostomy showed that this may not be the ideal solution.Further studies are needed to establish the best treatment for patients with bilateral stones or unilateral disease and a dilated extrahepatic duct. | Paulo Herman Marcos V Perini Vincenzo Pugliese Julio Cesar Pereira Marcel Autran C Machado William A Saad Luiz AC D'Albuquerque Ivan Cecconello | 2010 | World Journal of Gastroenterology2010，16，27： | 0 |
| 13 | A new heparin fragment decreases liver ischemia-reperfusion injury显示文摘To the Editor:Ischemia-reperfusion injury following surgery and transplantation can lead to irreversible multiorgan failure.Intracellular calcium overload is associated to cellular death during ischemiareperfusion.A recently discovered heparin fragment (HF),trisulfated disaccharide (TD),that acts on sodium-calcium exchanger(NCX) decreasing intracellular Ca^(2+),showed effectiveness on protecting hepatocytes from ischemia-reperfusion injury [1]. | Enio R Vasques Estela RR Figueira Joel A Rocha-Filho Cinthia Lanchotte Jorge LS Ximenes Helena B Nader Ivarne LS Tersariol Marcelo A Lima Tiago Rodrigues JoséEM Cunha Eleazar Chaib Luiz AC D’Albuquerque Flávio HF Galvão | 2022 | Hepatobiliary & Pancreatic Diseases International2022，21，2： | 0 |
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