维普中文期刊产品整合服务
6篇 您的检索式:作者名="Albader"
    题名 作者 年代 出处 被引量
1Bayesian Estimation of Outstandingclaim Reserves显示文摘Albade E 2002North American Actuarial2002,,6:1
2Bayesian Claim Reserving whenthere are Negative Values in the Runoff Tiangle显示文摘Albade E 2006Ac-tuarial Research Clearing House2006,,1:1
3CYP3A activity in severe liver cirrhosis correlates with C hild– P ugh and model for end‐stage liver disease ( MELD ) scores显示文摘Albader Albarmawi David Czock Annika Gauss Robert Ehehalt Justo Lorenzo Bermejo Jürgen Burhenne Tom M. Ganten Peter Sauer Walter E. Haefeli 2014Br J Clin Pharmacol2014,,1:1
4Therapeutic drug monitoring in inflammatory bowel disease:The dawn of reactive monitoring显示文摘Inflammatory bowel disease(IBD)is a chronic condition that significantly affects the quality of life of its patients.Biologic drugs have been the mainstay treatment in the management of IBD patients but despite their significant contribution,there remains a proportion of patients that do not respond or lose response to treatment.Therapeutic drug monitoring(TDM)involves measuring levels of serum drug concentrations and anti-drug antibodies.TDM of biologic drugs initially emerged to understand treatment failure in other immune mediated inflammatory diseases.This was then introduced in IBD to rationalize primary non-response or secondary loss of response,given that low serum drug concentrations or the formation of anti-drug antibodies are variably associated with treatment failure.The aim of this narrative review is to provide an overview regarding the current use of TDM in clinical practice and to present the evidence available regarding its use in both proactive and reactive clinical settings in preventing and managing treatment failure.This review also presents the existing evidence regarding the association of various clinical outcomes with specific thresholds of drug concentrations,in everyday practice.A narrative review of published articles and conference abstracts regarding the use of TDM in IBD management,through an electronic search using PubMed and ScienceDirect.TDM has proven to be superior and more cost effective in guiding management of patients with treatment failure compared to empiric dose escalation or change in treatment.Despite a trend towards an association between clinical outcomes and drug concentrations,proactive TDM based strategies have not been shown to achieve clear benefit in long-term outcomes.In the clinical setting,TDM has proven to be useful in managing IBD patients,and its use in the reactive setting,as an additional tool to help manage patients with treatment failure,is being promoted as newer guidelines and consensus groups implement TDM as part of the management plan.Farah Albader Petra Anna Golovics Lorant Gonczi Talat Bessissow Waqqas Afif Peter Laszlo Lakatos 2021World Journal of Gastroenterology2021,27,37:1
5Correlation between fungi isolated from burn wounds and burn care u- nits显示文摘Mousa HA AlBader SM Hassan DA 1999Burns1999,25,2:1
6运用COBAS AMPLICOR HCV系统快速检测HCV RNA显示文摘近年来实验室诊断丙型肝炎病毒(HCV)PCR法已向标准化和“即可用”的方向发展。本试验用来自5个检测中心的2000多份标本对首台自动化扩增和检测HCV RNA的仪器COBAS在日常实验室工作中的性能进行了评估。结果表明,自动的COBAS法与AMPLICOR手工法同样准确,符合率达99.8%。PCR法与血清学方法的结果并不完全一致,因为抗HCV抗体的存在有可能表示隐性感染或既往感染。江志奎 Albad,J 1999国外分析仪器技术与应用1999,,4:0
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费