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    题名 作者 年代 出处 被引量
1Supporting traditional PBL with online discussion forums:a study from Qassim Medical School 显示文摘Alamro AS Schofield S 2012Med Teach2012,34,1:1
2Intensity-modulated radiotherapy with simultaneous modulated accelerated boost technique and chemotherapy in patients with nasopharyngeal carcinoma显示文摘Fareed MM AlAmro AS Bayoumi Y 0,,:1
3Neoadjuvant chemotherapy followed by concurrent chemo radiation therapy in locally advanced nasopharyngeal carcinoma 显示文摘Alamro A Alrajhi N Khafaga Y 2005Int J Radiat Oncol Biol Phys2005,62,2:1
4The expressional level of tankyrase-1 gene and its regulation in colorectal cancer in a Saudi population显示文摘Tankyrase1(TNKS1)plays an essential role in cancer progression by regulating telomere length.The study aimed to determine expression of TNKS1 and its regulation in colorectal cancer(CRC)in 20 samples from Saudi patients.mRNA expression of TNKS1 in CRC and paired normal tissues was measured by qRT-PCR.Epigenetic modification of TNKS1 promoter was determined by methylation-specific PCR while somatic mutation was analyzed by Sanger sequencing in exon 10 of the gene.All cancerous and normal tissues expressed TNKS1,but level of expression in CRC tissues was significantly associated with tumor stage though no other parameters;age,gender,and tumor location,showed any correlation.Expression of TNKS1 was markedly higher in earlier(I,II)than in later(Ⅲ,Ⅳ)stages of CRC development.Both cancerous and healthy tissues had unmethylated promoters.Sanger sequencing of exon 10 masked any somatic mutation in the samples.Our findings suggest that up-regulation of TNKS1 was inversely correlated with cancer progression in CRC,indicating that TNKS1 participates in the initiation of CRC by stabilizing telomere length in the first phase of cancer progression.Mechanisms other than TNKS1 might play a role in malignant tumor progression and telomere maintenance in the late stages of CRC.HALA ABDULAZIZ M ALWARTHAN MOHAMMAD SAUD AL ANAZI NARASIMHA RPARINE RAMESA SHAFI BHAT GHADAH ALAMRO FTOON ALJARBOU SOOAD K AL-DAIHAN 2019BIOCELL2019,43,2:0
5针刺治疗勃起功能障碍安全性及疗效的评价显示文摘目的:评价针刺治疗勃起功能障碍的安全性及疗效。方法:采用文献检索法对相关研究进行系统检索。利用Popline、世界卫生组织(WHO)全球卫生图书馆(GHL)、欧洲灰色文献信息系统(SIGLE)、Scopus、美国科学信息研究所(ISI)Web of Science、PubMed和VHL 7个电子数据库进行检索。通过从收录文章的参考文献、PubMed和谷歌学术的相关论文以及引用收录论文的初步研究中搜索相关刊物,并进行进一步人工搜索。此外,对每个关键词都进行手动检索以避免遗漏相关文献。结果:用Endnote软件剔除重复文献后,共得到2818篇文献。有21项研究符合全文筛选的条件,其中5项随后被纳入。加上从手动检索中确定的2项研究后,共有7项研究适合进行系统性回顾和meta分析。其中5项用于定量和定性分析,2项仅用于定性分析。共有4项临床试验、1项初步研究、1份病例报告和1项动物研究。结论:针刺治疗能够改善男性勃起功能。Munirah Mansour Alamro 2021Journal of Acupuncture and Tuina Science2021,19,3:0
6Adaptation of Federated Explainable Artificial Intelligence for Efficient and Secure E-Healthcare Systems显示文摘Explainable Artificial Intelligence(XAI)has an advanced feature to enhance the decision-making feature and improve the rule-based technique by using more advanced Machine Learning(ML)and Deep Learning(DL)based algorithms.In this paper,we chose e-healthcare systems for efficient decision-making and data classification,especially in data security,data handling,diagnostics,laboratories,and decision-making.Federated Machine Learning(FML)is a new and advanced technology that helps to maintain privacy for Personal Health Records(PHR)and handle a large amount of medical data effectively.In this context,XAI,along with FML,increases efficiency and improves the security of e-healthcare systems.The experiments show efficient system performance by implementing a federated averaging algorithm on an open-source Federated Learning(FL)platform.The experimental evaluation demonstrates the accuracy rate by taking epochs size 5,batch size 16,and the number of clients 5,which shows a higher accuracy rate(19,104).We conclude the paper by discussing the existing gaps and future work in an e-healthcare system.Rabia Abid Muhammad Rizwan Abdulatif Alabdulatif Abdullah Alnajim Meznah Alamro Mourade Azrour 2024Computers, Materials & Continua2024,78,3:0
7Efficacy of intragastric balloon on weight reduction:Saudi perspective显示文摘AIM To evaluate the safety and efficacy of intragastric balloon(IGB) in weight reduction in obese patients referred to a tertiary hospital in the Kingdom of Saudi Arabia.METHODS Three hundred and one consecutive obese individuals, who underwent IGB placement during January 2009 to May 2015, were analyzed. The subjects aged 18 to 60 years and had a minimum body mass index(BMI) of 27 kg/m^2. The IGB was placed under conscious sedation and kept for 6 mo. Anthropometric measurements were recorded during and after 6 mo of IGB removal.RESULTS The body weight, excess body weight, and BMI were significantly reduced at the time of IGB removal and 6 mo later. Body weight loss > 10% was achieved in 224 subjects at removal of IGB. End of treatment success and long-term success were both significantly observed in women(70 vs 11)(71 vs 12.5) respectively. Excess BMI loss was significantly higher in subjects retaining the IGB for over 6 mo both at the removal [43.44 ± 19.46(n = 221) vs 55.60 ± 28.69(n = 80); t = 4.19, P = 0.0001] as well as at the end of 6 mo' follow-up [46.57 ± 24.89(n = 221) vs 63.52 ± 31.08(n = 80); t = 4.87, P = 0.0001]. Within 3 d of IGB placement, two subjects developed pancreatitis and one subject developed cardiac arrhythmia. Intestinal obstruction due to displacement of IGB occurred in two subjects. Allthese subjects recovered uneventfully after immediate removal of the IGB. CONCLUSION IGB was effective in our cohorts. The observed weight reduction was maintained for at least 6 mo post IGB removal. IGB placement was safe with a satisfactory tolerance rate.Ebtissam Saleh Almeghaiseeb Muhammad Farooq Ashraf Reem Abdullah Alamro Abdulaziz Omar Almasoud Abdulrahman Ali Alrobayan 2017World Journal of Clinical Cases2017,5,4:0
8Diabetes mellitus is not associated with worse short term outcome in patients older than 65 years old post-liver transplantation显示文摘BACKGROUND Non-alcoholic fatty liver disease is a global health care challenge and a leading indication of liver transplantation(LT).Hence,more patients with diabetes mellitus(DM)are undergoing LT,especially,above the age of 65.AIM To evaluate the impact of DM on short-term outcomes post-LT in patients over the age of 65.METHODS We collected data of patients who underwent LT from January 2001 until December 2019 using our electronic medical record.We assessed the impact of DM on short-term outcomes,one-year,post-LT based on the following variables:Survival at one year;acute cellular rejection(ACR)rates;intensive care unit(ICU)and hospital length of stay;and readmissions.RESULTS Total of 148 patients who are 65 year or older underwent LT during the study period.The mean age is 68.5±3.3 years and 67.6%were male.The median Model for End-stage Liver Disease score at time of transplantation was 22(6-39),39%of patients had hepatocellular carcinoma and 77.7%underwent living donor LT.The one-year survival was similar between DM patients and others,91%.ACR occurred in 13.5%of patients(P=0.902).The median ICU stay is 4.5-day P=0.023.The rates of ICU and 90-d readmission were similar(P=0.821)and(P=0.194),respectively.CONCLUSION The short-term outcome of elderly diabetic patients undergoing LT is similar to others.The presence of DM in elderly LT candidates should not discourage physicians from transplant consideration in this cohort of patients.Saad Alghamdi Shaden Alamro Dhari Alobaid Elwy Soliman Ali Albenmousa Khalid Ibrahim Bzeizi Saleh Alabbad Saleh A Alqahtani Dieter Broering Waleed Al-Hamoudi 2023World Journal of Hepatology2023,15,2:0
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