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| 1 | 不同缺血再灌注时间对大鼠离体心脏缺血/再灌注损伤的影响显示文摘目的 探讨不同缺血时间和再灌注时间对大鼠离体心脏缺血/再灌注损伤的影响。方法 采用Langendorff离体心脏灌流模型,将雄性SD大鼠离体心脏随机分成4组:正常对照组(normal,n=6)、缺血20 min组(I20,n=7)、缺血30 min组(I30,n=8)、缺血40 min组(I40,n=8),观察不同缺血时间组缺血前和再灌注120 min期间冠脉流量、冠脉流出液中肌酸激酶和乳酸脱氢酶的活力及心功能参数的变化,并用2,3,5-三苯基氯化四氮唑(2,3,5-triphenyltetrazolium chlorid,TTC)染色法计算心肌梗死面积。结果 与正常对照组相比,I20组、I30组、I40组的冠脉流量、心率、左室发展压及最大上升/下降速率均有所降低(P〈0.01,P〈0.05),且随再灌注时间的延长而有不同程度的减轻,其中I30组的心肌梗死面积随再灌注时间的延长而逐渐增大,但组内上述指标再灌注30、60、120 min相比均未见统计学差异。各缺血组的心肌酶在再灌注初期明显升高(P〈0.01),均在再灌注20 min时达到峰值。且此模型受缺血时间影响较大,I20组造成的损伤较为轻微,而I40组造成的损伤较为严重。结论 制备Langendorff大鼠离体心脏缺血/再灌注损伤模型建议以缺血30 min,再灌注30~60 min为宜。 | 于佳慧 李玉红 段真珍 王玲燕 Mary Akinyi 樊官伟 | 2014 | 中国药学杂志2014，49，18： | 9 |
| 2 | Trade-offs and synergies of climate change adaptation strategies among smallholder farmers in sub-Saharan Africa:A systematic review显示文摘Climate change adaptation strategies provide a cushion for smallholder farmers,especially in subSaharan Africa against the risks posed by climate hazards such as droughts and floods.However,the decision-making process in climate adaptation is complex.To better understand the dynamics of the process,we strive to answer this question:what are the potential trade-offs and synergies related to decision-making and implementation of climate adaptation strategies among smallholder farmers in sub-Saharan Africa region?A systematic literature review methodology was used through the Preferred Reporting Items for Systematic Review and Meta-Analysis(PRISMA)statement with the four-stage inclusion/exclusion criteria to identify the literature from selected databases(Scopus and Google Scholar).The climate adaptation strategies are organized into five broad categories(crop management,risk management,soil/land management,water management,and livestock management strategies).Evidence suggests that potential trade-offs may arise concerning added costs,additional labor requirements,and competition among objectives or available resources.The synergies,on the other hand,arise from implementing two or more adaptation strategies concurrently in respect of increased productivity,resilience,yield stability,sustainability,and environmental protection.Trade-offs and synergies may also differ among the various adaptation strategies with minimum/zero tillage,comparatively,presenting more tradeoffs.The development and promotion of low-cost adaptation strategies and complementary climate adaptation options that minimize the trade-offs and maximize the synergies are suggested.Skills and knowledge on proper implementation of climate change adaptation strategies are encouraged,especially at the local farm level. | Devinia Princess Akinyi Stanley Karanja Ng’ang’ Evan Hartunian Girvetz | 2021 | Regional Sustainability2021，2，2： | 4 |
| 3 | Relationships between native tree species and soil properties in the indigenous forest fragments of the Eastern Arc Mountains of the Taita Hills, Kenya显示文摘The relationship between soil properties and spatial distribution of native woody species was studied in three Taita Hills forest fragments which, although degraded, are ranked among 34 biodiversity hotspots of the world due to their high biodiversity of both plant and animal species. This relationship was assessed by using Spearman correlation and principal component analyses (PCA). The results of these analyses should be useful in instituting forest restoration programs that are crucial for the forests. Both the soil and vegetation studied were sampled from 17 subplots in the natural forest fragments of Ngangao (120 ha), Chawia (86 ha) and Mbololo (185 ha). The soil variables measured were: pH, texture, soil nutrients of C, N, Ca, P, K, Mg and Na. In total 36 native tree species from 13 families were identified from the three forest fragments. Ordination results show that axis 1 accounted for 35% and axis 2 for 25% of the total variation in species composition, indicating that the structure of vegetation is related to two major environmental gradients. The correlation analyses of species and soil properties showed that Na and clay particles were the most important determinants of species distribution; pH and soil variables such as C, N, Ca and P also played minor roles. Unexpectedly, some species (e.g. Psychotria petitii) showed positive relationships with Na attributed to possible substitution for K. Relationships with P were both positive (e.g. Craibia zimmermannii) and negative (e.g. Albizia gummifera) with some species, attributable to pH levels. An ANOVA for soil variables showed that there were differences in the Ca content in Mbololo (due to the parent material) and P in Ngangao where a special relationship was observed between some of the species. The presence of gaps accounted for the distribution of seedlings but not for the saplings, whose distribution responded more to factors similar to those to which mature trees respond. Soil-species relationships that were established may be utilized along with soil analyses when choosing native species for restoration. | Loice Mildred Akinyi OMORO Raija LAIHO Michael STARR Petri K.E.PELLIKKA | 2011 | Forestry Studies in China2011，13，3： | 2 |
| 4 | Ubiquitin C-terminal hydrolase is a novel biomarker in humans for severe traumatic brain injury显示文摘 | Papa L Akinyi L Liu M C | 2009 | Crit Care Med2009，38，7： | 1 |
| 5 | Multiple genetic origins of histidine-rieh protein 2 gene deletion in Plasmodium falciparum parasites from Peru 显示文摘 | Akinyi S Hayden T Gamba D | 2013 | Sei Rep2013，3，2797： | 1 |
| 6 | Clinical utility of serum levels of ubiquitin c-terminal hydrolase as a biomarker for severe traumatic brain injury显示文摘 | Mondello S Akinyi L Buki A | | 0，，03： | 1 |
| 7 | Ubiquitin C-terminal hydrolase is a novel biomarker in humans for severe traumatic brain injury 显示文摘 | Papa L Akinyi Liu MC | 2009 | Crit Care Med2009，38，12： | 1 |
| 8 | Biochemical, structural, and biomarker evidence for calpain-mcdiated cy- toskeletal change after diffuse brain injury uncomplicated by contusion显示文摘 | MCGINN MJ KELLEY BJ AKINYI L | 2009 | 1 Neuropathol Exp Neurol2009，68，3： | 1 |
| 9 | Ubiquitin C terminal hydrolase is a novel biomarkerin humans for severe traumatic brain injury 显示文摘 | Papa L Akinyi L Liu MC | 2010 | Crit Care Med2010，38，1： | 1 |
| 10 | Phylogenetic and structural information on glyceraldehyde-3-phosphate dehydrogenase (G3PDH) in Plasmodium provides functional insights显示文摘 | Sheila Akinyi Jenny Gaona Esmeralda V.-S. Meyer John W. Barnwell Mary R. Galinski Vladimir Corredor | 2007 | Infection, Genetics and Evolution2007，，2： | 1 |
| 11 | Ubiquitin C-terminal hydrolase is a novel biomarker in humans for severe traumatic brain injury显示文摘 | Papa L Akinyi L Liu MC | | 0，，01： | 1 |
| 12 | Levels of UCH-L1 in human CSF and outcome following severe traumatic brain injury显示文摘 | Papa L Oli M Akinyi L | | 0，，07： | 1 |
| 13 | Ubiquitin C-terminal hydro- lase-L1 as a biomarker for ischemic and traumatic brain injury in rats显示文摘 | Liu MC Akinyi L Scharf D | 2010 | Eur J Neurosci2010，31，4： | 1 |
| 14 | Ubiquitin C-terminal hydrolase is a novel biomarker in humans for severe traumatic brain injury 显示文摘 | Papa L Akinyi L Liu MC | 2010 | Cfit Care Med2010，8，1： | 1 |
| 15 | Ubiquitin C-terminal hydro-lase is a novel biomarker in humans for severe traumatic brain injury 显示文摘 | Papa L Akinyi Liu MC | 2009 | Crit Care Med2009，38，12： | 1 |
| 16 | Ubiquitin C-terminal hydrolase is a novel biomarker in humans for severe traumatic brain injury 显示文摘 | Papa L Akinyi L Liu MC | 2009 | Crit Care Med2009，38，1： | 1 |
| 17 | Ubiqui- tin C-terminal hydrolase is a novel bio- marker in humans for severe traumatic brain injury 显示文摘 | Papa L Akinyi L Liu MC | 2010 | Crit Care Med2010，38，1： | 1 |
| 18 | Ubiquitin C-terminal hydrolase is a novel biomarker in humans for severe traumatic brain injury显示文摘 | Papa L Akinyi L Liu MC | 2010 | Crit Care Med2010，38，1： | 1 |
| 19 | Ubiquitin C-terminal hydrolase-L1 as a biomarker for ischemic and traumatic brain injury in rats显示文摘 | Liu MC Akinyi L Scharf D | | 0，，04： | 1 |
| 20 | Ubiquitin C-terminal hydrolase-L1 as a biomarker for ischemic and traumatic brain injury in rats显示文摘 | Liu MC Akinyi L Scharf D | 2010 | Eur J Neurosci2010，31，4： | 1 |
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