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| 1 | Efficacy of perioperative parecoxib injection on postoperative pain relief after laparoscopic cholecystectomy:A prospective,randomized study显示文摘AIM:To determine the efficacy of perioperative parecoxib injection on postoperative pain relief after laparoscopic cholecystectomy.METHODS: A prospective, double-blind, randomized, placebo-controlled study was conducted on 70 patients who underwent elective laparoscopic cholecystectomy under general anesthesia at Siriraj Hospital, Bangkok, from January 2006 to December 2007. Patients were randomized to receive either 20 mg parecoxib infusion 30 min before induction of anesthesia and at 12 h after the first dose (treatment group), or normal saline infusion, in the same schedule, as a placebo (control group). The degree of the postoperative pain was assessed every 3 h in the first 24 h after surgery, and then every 12 h the following day, using a visual analog scale. The consumption of analgesics was also recorded.RESULTS:There were 40 patients in the treatment group, and 30 patients in the control group. The pain scores at each time point, and analgesic consumption did not differ between the two groups. However,there were fewer patients in the treatment group than placebo group who required opioid infusion within the first 24 h (60% vs 37%, P=0.053).CONCLUSION: Perioperative administration of parecoxib provided no significant effect on postoperative pain relief after laparoscopic cholecystectomy. However, preoperative infusion 20 mg parecoxib could significantly reduce the postoperative opioid consumption. | Thawatchai Akaraviputh Charay Leelouhapong Varut Lohsiriwat Somkiat Aroonpruksakul | 2009 | World Journal of Gastroenterology2009，15，16： | 78 |
| 2 | Pre-operative hypoalbuminemia is a major risk factor for postoperative complications following rectal cancer surgery显示文摘AIM:To determine the relationship between pre-operative hypoalbuminemia and the development of complications following rectal cancer surgery, as well as postoperative bowel function and hospital stay. METHODS:The medical records of 244 patients undergoing elective oncological resection for rectal adenocarcinoma at Siriraj Hospital during 2003 and 2006 were reviewed. The patients had pre-operative serum albumin assessment. Albumin less than 35 g/L was recognized as hypoalbuminemia. Postoperative outcomes, including mortality, complications, time to first bowel movement, time to first defecation, time to resumption of normal diet and length of hospital stay, were analyzed. RESULTS:The patients were 139 males (57%) and 105 females (43%) with mean age of 62 years. Fifty-six patients (23%) had hypoalbuminemia. Hypoalbuminemic patients had a significantly larger tumor size and lower body mass index compared with non-hypoalbuminemic patients (5.5 vs 4.3 cm;P < 0.001 and 21.9 vs 23.2 kg/m2;P = 0.02, respectively). Thirty day postoperative mortality was 1.2%. Overall complication rate was 25%. Hypoalbuminemic patients had a significantly higher rate of postoperative complications (37.5% vs 21.3%;P = 0.014). In univariate analysis, hypoalbuminemia and ASA status were two risk factors for postoperative complications. In multivariate analysis, hypoalbuminemia was the only significant risk factor (odds ratio 2.22,95% CI 1.17-4.23;P < 0.015). Hospitalization in hypoalbuminemic patients was significantly longer than that in non-hypoalbuminemic patients (13 vs 10 d, P = 0.034), but the parameters of postoperative bowel function were not significantly different between the two groups. CONCLUSION:Pre-operative hypoalbuminemia is an independent risk factor for postoperative complications following rectal cancer surgery. | Varut Lohsiriwat Darin Lohsiriwat Wiroon Boonnuch Vitoon Chinswangwatanakul Thawatchai Akaraviputh Narong Lert-akayamanee | 2008 | World Journal of Gastroenterology2008，14，8： | 24 |
| 3 | colorectal 损害的内视镜的纹身: 它是一个无风险的过程吗?显示文摘 Endoscopic tattooing is one of the most useful tools for the localization of small colorectal lesions especially in the laparoscopic setting.This is a minimally invasive endoscopic procedure without risk of major complications.However,many studies have revealed complications resulting from this procedure.In this article,several topics are reviewed including the accuracy,substance preparation,injected techniques and complications related to this procedure. | Atthaphorn Trakarnsanga Thawatchai Akaraviputh | 2011 | World Journal of Gastrointestinal Endoscopy2011，3，12： | 7 |
| 4 | Colonoscopic perforation:A report from World Gastroenterology Organization endoscopy training center in Thailand显示文摘瞄准:决定 colonoscopic 穿孔(CP ) 的发生,并且从在泰国训练中心的世界肠胃病学组织(WGO ) 内视镜检查法与 CP 评估病人的临床的调查结果,管理和结果。方法:所有 colonoscopies 和 sigmoidoscopies 在内视镜的单位表现在 1999 和 2007 之间,药 Siriraj 医院的教师, Mahidol 大学,曼谷被考察。CP,病人的特征,内视镜的信息, intra 起作用的调查结果,管理和结果的发生被分析。结果:结肠(13699 colonoscopies 和 3658 灵活 sigmoidoscopies ) 的 17357 内视镜的过程的一个总数在 9 年的经期上在 Siriraj 医院里被执行。十五个病人(0.09%) 有 CP:14 从结肠镜检查并且 1 从乙状结肠镜检查。穿孔的最普通的地点在 S 字形的冒号(80%) ,由横向的冒号(13%) 列在后面。穿孔被直接损伤从柄或内诊镜的尖端引起(n = 12, 80%) 并且内视镜的 polypectomy (n = 3, 20%) 。有 CP 的所有病人经历了外科的管理:主要修理(27%) 和肠切除术(73%) 。死亡率是 13% ,手术后的复杂并发症率是 53% 。结论:CP 是稀罕却严肃的复杂并发症追随者结肠镜检查和乙状结肠镜检查,与病态和死亡的高率。CP 的发生是 0.09% 。外科仍然是 CP 管理的支柱。 | Varut Lohsiriwat Sasithorn Sujarittanakarn Thawatchai Akaraviputh Narong Lertakyamanee Darin Lohsiriwat Udom Kachinthorn | 2008 | World Journal of Gastroenterology2008，14，43： | 6 |
| 5 | Surgery for gastrointestinal malignant melanoma:Experience from surgical training center显示文摘AIM:To characterize clinical features,surgery,outcome,and survival of malignant melanoma(MM) of the gastrointestinal(GI) tract in a surgical training center in Bangkok,Thailand. METHODS:A retrospective review was performed for all patients with MM of the GI tract treated at our institution between 1997 and 2007. RESULTS:Fourteen patients had GI involvement either in a metastatic form or as a primary melanoma. Thirteen patients with sufficient data were reviewed. The median age of the patients was 66 years(range:32-87 years) .Ten patients were female and three were male.Seven patients had primary melanomas of the anal canal,stomach and the sigmoid colon(5,1 and 1 cases,respectively) .Seven patients underwent curative resections:three abdominoperineal resections,two wide local excisions,one total gastrectomy andone sigmoidectomy.Six patients had distant metastatic lesions at the time of diagnosis,which made curative resection an inappropriate choice.Patients who underwent curative resection exhibited a longer mean survival time(29.7 mo,range:10-96 mo) than did patients in the palliative group(4.8 mo,P=0.0006) . CONCLUSION:GI MM had an unfavorable prognosis,except in patients who underwent curative resection(53.8%of cases) ,who had a mean survival of 29.7 mo. | Thawatchai Akaraviputh Satida Arunakul Varut Lohsiriwat Cherdsak Iramaneerat Atthaphorn Trakarnsanga | 2010 | World Journal of Gastroenterology2010，16，6： | 5 |
| 6 | Comparison of early pre-cutting vs standard technique for biliary cannulation in endoscopic retrograde cholangiopancreatography: A personal experience显示文摘AIM: To compare the results and complications of early pre-cutting technique with standard technique. METHODS: From January 2003 to December 2004, a total of 416 consecutive therapeutic biliary ERCP procedures were performed by one endoscopist (T.A.). Data were retrospectively collected according to procedure indication and results. Of these, 293 procedures (70.4%) were done with standard technique (group A) and 123 procedures (29.6%) with early pre-cutting technique in case of difficult cannulation (group B). The results and complications of ERCP were compared. RESULTS: Success rate of first attempt cannulation was 98.0% in group A and 87.8% in group B. The overall incidence of post-ERCP pancreatitis, hemorrhage, perforation and cholangitis was 0%, 0.2%, 0.5% and 0.5%, respectively. Morbidity rate was not significantly different. No procedure-related mortality was occurred. CONCLUSION: For an experienced hand, the early pre-cutting technique for biliary cannulation is safe and effective as standard technique. | Kannikar Laohavichitra Thawatchai Akaraviputh Asada Methasate Somchai Leelakusolvong Udom Kachintorn | 2007 | World Journal of Gastroenterology2007，13，27： | 4 |
| 7 | Predictive significance of cancer related-inflammatory markers in locally advanced rectal cancer显示文摘BACKGROUND Locally advanced rectal cancer is treated using neoadjuvant chemoradiation(nCRT),followed by total mesorectal excision(TME).Tumor regression and pathological post-treatment stage are prognostic for oncological outcomes.There is a significant correlation between markers representing cancer-related inflammation,including high neutrophil-to-lymphocyte ratio(NLR),monocyteto-lymphocyte ratio(MLR),and platelet-to-lymphocyte(MLR)and unfavorable oncological outcomes.However,the predictive role of these markers on the effect of chemoradiation is unknown.AIM To evaluate the predictive roles of NLR,MLR,and PLR in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiation.METHODS Patients(n=111)with locally advanced rectal cancer who underwent nCRT followed by TME at the Minimally Invasive Surgery Unit,Siriraj Hospital between 2012 and 2018 were retrospectively analyzed.The associations between post-treatment pathological stages,neoadjuvant rectal(NAR)score and the pretreatment ratios of markers of inflammation(NLR,MLR,and PLR)were analyzed.RESULTS Clinical stages determined using computed tomography,magnetic resonance imaging,or both were T4(n=16),T3(n=94),and T2(n=1).The NAR scores were categorized as high(score>16)in 23.4%,intermediate(score 8-16)in 41.4%,and low(score<8)in 35.2%.The mean values of the NLR,PLR,and MLR correlated with pathological tumor staging(ypT)and the NAR score.The values of NLR,PLR and MLR were higher in patients with advanced pathological stage and high NAR scores,but not statistically significant.CONCLUSION In patients with locally advanced rectal cancer,pretreatment NLR,MLR and PLR are higher in those with advanced pathological stage but the differences are not significantly different. | Kitinat Timudom Thawatchai Akaraviputh Vitoon Chinswangwatanakul Ananya Pongpaibul Pornpim Korpraphong Janjira Petsuksiri Suthinee Ithimakin Atthaphorn Trakarnsanga | 2020 | World Journal of Gastrointestinal Surgery2020，12，9： | 3 |
| 8 | Endoscopic treatment of a large colonic polyp as a cause of colocolonic intussusception in a child显示文摘Colocolonic intussusception is an uncommon cause of intestinal obstruction in children.The most common type is idiopathic ileocolic intussusception.However,pathologic lead points occur approximately in 5%of cases.In pediatric patients,Meckel’s diverticulum is the most common lead point,followed by polyps and duplication.We present a case of recurrent colocolonic intussusception which caused colonic obstruction in a 10-year-old boy.A barium enema revealed a large polypoid mass at the transverse colon.Colonoscopy showed a colonic polyp,3.5 centimeters in diameter,which was successfully removed by endoscopic polypectomy. | Nutnicha Suksamanapun Mongkol Uiprasertkul Ravit Ruangtrakool Thawatchai Akaraviputh | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，7： | 2 |
| 9 | The learning curve for safety and success of precut sphincterotomy for therapeutic ERCP: a single endoscopist’s experience显示文摘 | T. Akaraviputh V. Lohsiriwat J. Swangsri A. Methasate S. Leelakusolvong N. Lertakayamanee | 2008 | Endoscopy2008，，06： | 2 |
| 10 | A same day approach for choledocholithiasis using endoscopic stone removal followed by laparoscopic cholecystectomy: a retrospective study显示文摘 | Akaraviputh T Rattanapan T Lohsiriwat V Methasate A Aroonpruksakul S Lohsiriwat D | 2009 | J Med Assoc Thai2009，92，： | 1 |
| 11 | Simplified technique of laparoscopic cholecystectomyin a patient with situs inversus: a case report and review oftechniques显示文摘 | PHOTHONG N AKARAVIPUTH T CHINSWANGWATANAKULV | 2015 | BMC Surg2015，1523，： | 1 |
| 12 | Surgical outcomes of Lichtenstein tension - free he~ioplasty for acutely incarcerated ingui nd hernia 显示文摘 | Lohsiriwat V Sridermma W Akaraviputh T | 2007 | Surg Today2007，37，3： | 1 |
| 13 | A sia– P acific consensus recommendations for endoscopic and interventional management of hilar cholangiocarcinoma显示文摘 | Rungsun Rerknimitr Phonthep Angsuwatcharakon Thawee Ratanachu‐ek Christopher J L Khor Ryan Ponnudurai Jong Ho Moon Dong Wan Seo Linda Pantongrag‐Brown Apichat Sangchan Pises Pisespongsa Thawatchai Akaraviputh Nageshwar D Reddy Amit Maydeo Takao Itoi Nonth | 2013 | J Gastroenterol Hepatol2013，，4： | 1 |
| 14 | Surgical outcomes of Lichtenstein tension - free hernioplasty for acutely incarcerated inguinal hernia 显示文摘 | Lohsiriwat V Sridermma W Akaraviputh T | 2007 | Surg Today2007，37，3： | 1 |
| 15 | Surgical outcoms of Lichtenstein tension-free hemioplasty for acutely incarcerated inguinal hemia显示文摘 | Lohsiriwat V Srtdermma W Akaraviputh T | 2007 | Surg Today2007，37，3： | 1 |
| 16 | Surgical Outcomes of Lichtenstein Tension-Free Hernioplasty for Acutely Incarcerated Inguinal Hernia显示文摘 | Varut Lohsiriwat Wasupong Sridermma Thawatchai Akaraviputh Wiroon Boonnuch Vitoon Chinsawangwatthanakol Asada Methasate Narong Lert-akyamanee Darin Lohsiriwat | 2007 | Surgery Today2007，，3： | 1 |
| 17 | Surgical outcomes of Liehtenstein tension-free hemioplasty for acutely ineareerated inguinal hernia显示文摘 | Lohsiriwat V Sridermma W Akaraviputh T | 2007 | Surg Today2007，37，3： | 1 |
| 18 | Lymph node metastasis in gastric cancer: result of D2 dissection显示文摘 | METHASATE A TRAKARNSANGA A AKARAVIPUTH T | 2010 | J Med Assoc Thai2010，93，3： | 1 |
| 19 | Simplified technique of laparoscopic cholecystectomy in a patient with situs inversus : a case report and review of techniques 显示文摘 | Phothong N Akaraviputh T Chinswangwatanakul V | 2015 | BMC Surg2015，15，： | 1 |
| 20 | Long- term results of large diameter hepaticojejunostomy for treatment of Bile Duct Injuries following eholeeystectomy 显示文摘 | Akaraviputh T Boonnuch W Lohsiriwat V | 2006 | J Med Assoc Thai2006，89，5： | 1 |
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