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| 1 | SMARCA4缺失型鼻窦癌:10例SWI/SNF驱动的鼻窦恶性肿瘤遗传学谱系的扩展显示文摘低分化鼻窦癌的分子发病机制近年来备受关注。在鼻窦未分化癌的形态学谱系中,几种未分类的癌被重新归类为具有独特遗传学特征的变异体或实体,包括NUT重排性癌和SMARCB1缺失型癌。作者进一步描述了一种罕见的鼻腔未分化癌样肿瘤,其特征是通过免疫组化染色可检测到SWI/SNF构建体SMARCA4(BRG1)的失活。 | Agaimy A Jain D Uddin N 魏建国(摘译) 袁晓露(审校) | 2020 | 临床与实验病理学杂志2020，36，5： | 8 |
| 2 | Perivascular epithelioid cell tumor of the liver coexisting with a gastrointestinal stromal tumor显示文摘Approximately 10% of patients with gastrointestinal stromal tumors (GIST) develop other neoplasms, either synchronously or metachronously. In this report we describe coexistence of a gastrointestinal stromal tumor and a hepatic perivascular epithelioid cell tumor (PEComa) in a 51-year-old woman with no evidence of tuberous sclerosis. A subcapsular hepatic nodule (0.8 cm in diameter) was found during surgery for symptomatic gastric neoplasm (15 cm in diameter) arising from the lesser curvature. Both tumors revealed histomorphological and immunohistochemical features confirming a diagnosis of a small incidental hepatic PEComa and a high risky extramural gastric GIST, respectively. The patient remained disease-free 25 mo after surgery with no evidence of tumor recurrence or new neoplasms. To our knowledge, this is the first report of PEComa in a patient with GIST. Hepatic lesions detected synchronously or metachronously in patients with GISTs may represent histogenetically distinct lesions and should be sampled to confirm or exclude metastatic GISTs. | Carlos Eduardo Paiva Francisco Alves Moraes Neto Abbas Agaimy Maria Aparecida Custódio Domingues Silvia Regina Rogatto | 2008 | World Journal of Gastroenterology2008，14，5： | 6 |
| 3 | 副睾低级别子宫内膜间质肉瘤:1例报道并分子证实JAZF1/SUZ12易位显示文摘发生在睾丸及其附件起源于苗勒管样浆液型或黏液型的肿瘤极其罕见,近年来也被逐渐认识。伴或不伴卵巢样间质的囊腺瘤、交界性肿瘤或囊腺癌是主要的类型。尽管有少数子宫内膜样腺癌的报道,但据作者所知,目前文献仍没有子宫内膜间质肿瘤的报道。作者报道1例发生在59岁男性左侧阴囊内直径2 cm的肿块,超声检测该肿块位于附睾尾,血供丰富。该患者平素体健,无重大疾病史,无内分泌疾病或外用激素治疗史。睾丸肿瘤标志物指标(β-HCG,AFP)正常。 | Agaimy A Moskalev E A Weisser W 赵芳 魏建国 | 2018 | 临床与实验病理学杂志2018，34，9： | 4 |
| 4 | Lymph node metastasis in gastrointestinal stromal tumours (GIST) occurs preferentially in young patients ≤40?years: an overview based on our case material and the literature显示文摘 | Abbas Agaimy Peter H. Wünsch | 2009 | Langenbeck’s Archives of Surgery2009，，2： | 3 |
| 5 | 横纹肌样及未分化表型的肾细胞癌:32例分析提示未分化肿瘤具有与SWI/SNF复合体缺陷有关的不同于常见的分化通路显示文摘肾细胞癌出现未分化(间变性)和横纹肌样细胞特征时被公认为预后不良,其分子机制尚未充分阐明。近期研究发现SWI/SNF染色质重塑复合体是不同器官具有未分化和横纹肌样特征癌的分子机制。本文对32例未分化肾细胞癌(均具有未分化和明显横纹肌样特征,可有或无普通型肾细胞癌成分)的分子特征进行分析。 | Agaimy A Cheng L Egevad L 向娟 余英豪 | 2017 | 临床与实验病理学杂志2017，33，7： | 2 |
| 6 | Nature:研究鉴定出侵袭性胰腺癌细胞及其弱点显示文摘在一项新的研究中,来自美国德州大学MD安德森癌症中心的研究人员利用患者源性肿瘤异种移植(patient—derived tumorxenograft,PDx)和模式小鼠开展一系列临床前实验,鉴定出一种门卫蛋白(gatekee Perprotein)阻止胰腺癌细胞转化为一种极具侵袭性的细胞类型,并且也发现剔除这种门卫蛋白的疗法能够阻止这些癌细胞。这些发现有助为携带这种进展迅速的治疗抵抗性的胰腺癌细胞亚群的患者开发出潜在的疗法。 | Genovese, Giannicola Carugo, Alessandro Tepper, James Robinson, Frederick Scott Li, Liren Svelto, Maria Nezi, Luigi Corti, Denise Minelli, Rosalba Pettazzoni, Piergiorgio Gutschner, Tony Wu, Chia-Chin Seth, Sahil Akdemir, Kadir Caner Leo, Elisabetta Amin, Samirkumar Dal Molin, Marco Ying, Haoqiang Kwong, Lawrence N. Colla, Simona Takahashi, Koichi Ghosh, Papia Giuliani, Virginia Muller, Florian Dey, Prasenjit Jiang, Shan Garvey, Jill Liu, Chang-Gong Zhang, Jianhua Heffernan, Timothy P. Toniatti, Carlo Fleming, Jason B. Goggins, Michael G. Wood, Laura D. Sgambato, Alessandro Agaimy, Abbas Maitra, Anirban Roberts, Charles W. M. Wang, Huamin Viale, Andrea DePinho, Ronald A. Draetta, Giulio F. Chin, Lynda | 2017 | 现代生物医学进展2017，17，14： | 2 |
| 7 | Collecting duct Carcinoma versus renal medullary carcinoma: an appeal for nosologic and biological clarity显示文摘 | Amin M B Smith S C Agaimy A | 2014 | Am J Surg Pathol2014，38，7： | 1 |
| 8 | Follicular dendritic cell tumor of the gastrointestinal tract:report of a rare neoplasm and literature review显示文摘 | Agaimy A Wünsch P H | | 0，，07： | 1 |
| 9 | SMARCBI(INI1)-defi- cient sinonasal basaloid carcinoma: a novel member of the ex- panding family of SMARCBl-deficient neoplasms显示文摘 | AGAIMY A KOCH M LELL M | 2014 | Am J Surg Pathol2014，38，9： | 1 |
| 10 | Occurrence of other malignancies in patients withgastrointestinal stromal tumors显示文摘 | Agaimy A Wünsch PH Sobin LH | 2006 | Semin Diagn Pathol2006，23，2： | 1 |
| 11 | Multiple sporadic gas-troin- testinal stromal tumours arising at different gastrointestinal sites: pattern of involvement of the muscularis propria as a clue to inde- pendent primary GISTs 显示文摘 | Agaimy A Markl B Arnholdt H | 2009 | Virchows Arch2009，455，2： | 1 |
| 12 | Impact of serosal involve- ment/extramural growth on the risk of synchronous and metachronous peritoneal spread in gastrointestinal stromal tumors: proposal for a macroscopic classification of GIST显示文摘 | Agaimy A Vassos N Wunsch P H | 2012 | Int J Clin Exp Pathol2012，5，1： | 1 |
| 13 | Calcifying fibrous tumor of the stomach:clinicopathologic and molecular study of seven cases with literature review and reappraisal of histogenesis显示文摘 | Agaimy A Bihl MP Tornillo L | | 0，，2： | 1 |
| 14 | Minute gastric sclerosingstromal tumors (GIST tumorlets) are common in adults and frequentlyshow c-KIT mutations 显示文摘 | Agaimy A Wunsch PH Hofstaedter F | 2007 | AmJ Surg Pathol2007，31，1： | 1 |
| 15 | Lymphatics and D2-40/podoplanin expression in gastrointestinal stromal turnouts of the stomach with and without lymph node metastasis:an immunohistochemical study with special reference to the Carney triad显示文摘 | Agaimy A Carney JA | 2010 | J Clin Pathol2010，63，3： | 1 |
| 16 | Outcome af- ter resection of one hundred gastrointestinal stromal tumors显示文摘 | KRAJINOVIC K GERMER CT AGAIMY A | 2010 | Digestive Surgery2010，27，4： | 1 |
| 17 | Outcome after resection ofone hundred gastrointestinal stromal tumors 显示文摘 | Krajinovic K Germer CT’Agaimy A | 2010 | Dig Surg2010，27，4： | 1 |
| 18 | Calcifying fibroustumor of the stomach : clinicopathologic and molecular study ofseven cases with literature review and reappraisal ofhistogenesis 显示文摘 | Agaimy A Bihl M P Tomillo L | 2010 | Am J Surg Pathol2010，34，2： | 1 |
| 19 | V600E BRAF mutations are alternative early molecular events in a subset of KIT/ PDGFRA wild-type gastrointestinal stromal tumours 显示文摘 | Agaimy A Terracciano LM Diruhofer S | 2009 | J Clin Pathol2009，62，7： | 1 |
| 20 | Gastrointestinal stromal tumors(GIST)from riskstratification systems to the new TNM proposal:more questions thananswers显示文摘 | Agaimy A | 2010 | Int J Clin Exp Pathol2010，3，5： | 1 |
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