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| 1 | Attenuation of oxidative stress and hepatic damage by some fermented tropical legume condiment diets in streptozotocin-induced diabetes in rats显示文摘Objective:To investigate the modulatory effect of fermented legume condiments diet on oxidative stress in streptozotocin(STZ) induced diabetic rats.Methods:Adult male Wistar rats were randomly divided into six groups with six animals in each group.Diabetes was induced by intraperitoneal injection of STZ(35 mg/kg b.w.).After being confirmed diabetic,the rats were fed with fermented Bambara groundnut.Locust bean and Soybean diets for 14 days.The plasma was obtained after 14-day treatment and analyzed for hepatic damage marker enzymes(AST,ALT and ALP) and in vivo antioxidant indices.Results:The diabetic untreated rats showed elevated (P<0.05) levels of AST,ALT.ALP and malondialdehyde with reduced activities of glutathiones -transferase,catalase as well as plasma reduced glutathione,vitamin C and total protein content.However,treatment of diabetic rats with lermenled legume condiments diets for 14 days significantly(P<0.05) reversed the above parameters towards normalcy,suggesting their modulation of oxidative stress,which mav be due to their high phenolic content and antioxidant capacity.Conclusions:The attenuation of oxidative stress and protection of hepatic tissue damage by the legume condiment diets in STZ induced diabetic rats compare favourably with that of metformin,a well known oral hypoglycemic drug. | Adedayo O Ademiluyi Ganiyu Oboh | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，9： | 3 |
| 2 | Antioxidant Contents (Vitamin C) of Raw and Blanched Different Fresh Vegetable Samples显示文摘 | Oluwafunmilayo O. Olayinka Ajibola M. Kareem Isaac B. Ariyo Stephen K. Omotugba Adedayo O. Oyebanji | 2012 | 世界最新医学信息文摘2012，12，2： | 2 |
| 3 | Breast cancer subtypes based on ER/PR and Her2 Ex pression : comparison of clinicopathologic features and sur-vival显示文摘 | Adedayo A Onitilo Jessica M Engel Robert T Greenlee | 2009 | Clin Med Res2009，7，： | 1 |
| 4 | Breast cancer incidence before and after diagnosis of type 2 diabetes naellitus in women: increased risk in the prediabetes phase显示文摘 | Adedayo A Onitilo Rachel V Stankowski Richard L Berg | 2014 | European journal of cancer prevention : the official journal of the European Cancer Prevention Or- ganisation (ECP)2014，23，2： | 1 |
| 5 | Modulatory effects of dietary inclusion of garlic(Allium sativum) on gentamycin-induced hepatotoxicity and oxidative stress in rats显示文摘Objective:To investigate die ameliorative effect of dietary inclusion of garlic(Allium sativum)on gentamycin-induced hepatotoxicity in rats.Methods:Adult male rats were randomly divided into four groups with sis animals in each group.Groups 1 and 2 were fed basal diet while Groups 3 and 4 were fed diets containing 2%and 4%garlic respeetively for 27 d prior to gentamycin administration.Hepatotoxicity was induced by the intraperitoneal administration at gentamycin(100 mg/kg body weight)for 3 d.The liver and plasma were studied for hepatotoxicity and antioxidant indices.Results:Gentamycin induces hepatic damage as revealed by significant(P<0.05)elevation of liver damage marker enzymes(aspartate transaminase and alanine aminotransferase)and reduction in plasma albumin level.Gentamycin also eaused a significant(P<0.05)alteration in plasma and liver enzymatic(catalase,glutathione and super oxygen dehydrogenises)and non-enzymatic(glutathione and vitamin C)antioxidant indices with concomitant increase in the malondialdehyde content;however,there was a significant(P<0.05)restoration of the antioxidant status coupled with significant(P<0.05)decrease in the tissues malondialdehyde content,following consumption of diets containing garlic.Conclusions:These results suggest that dietary inclusion of garlic powder could protect against gentamycin-induced hepatotoxicity,improve antioxidant status and modulate oxidative stress;a function attributed to their phenolic constituents. | Adedayo O Ademiluyi Ganiyu oboh Tosin R Owoloye Oluwaseun J Agbebi | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，6： | 1 |
| 6 | A pharmacokinetic Study of Amphotericin B Lipid Complex Infet al (Abelcet) in Patients with Definite or Probable Systemic Fungal Infet alions显示文摘 | Adedayo Adedoyin Christine E Suenson Lois E Bolcsak | 2000 | Antimicrob Agents Chemother2000，44，： | 1 |
| 7 | ADME - Tox in drug discovery: integration of experimental and computational technologies显示文摘 | Hongshi Yu and Adedayo A | 2003 | DDT2003，8，18： | 1 |
| 8 | Histological study of smoke extract of Tobacco nicotiana on the heart, liver, lungs, kidney, and testes of male Sprague-Dawleyrats显示文摘 | Adedayo A D Tijani A A Musa A A | 2011 | Nigeria MedJ2011，52，4： | 1 |
| 9 | Hyperinfective strongyloidiasis in the medical ward : review of 27 cases in 5 years 显示文摘 | Adedayo O Grell G Bellot P | 2002 | South Med J2002，95，7： | 1 |
| 10 | Effects of in utero tributyltin chloride exposure in the rat on pregnancy outcome 显示文摘 | Adedayo A Daming L Don SF | | Reprod Dev Toxieol0，74，： | 1 |
| 11 | Transient fan architecture and depositional controls from near-surface 3-D seismic data,Niger delta continental slope显示文摘 | Adedayo A A Timothy R M Stephan A G | 2005 | AAPG Bulletin2005，89，3： | 1 |
| 12 | Diabetes and cancer I: risk, survival, and implications for screening显示文摘 | Adedayo Onitilo Jessica Engel Ingrid Glurich Rachel Stankowski Gail Williams Suhail Doi | 2012 | Cancer Causes & Control2012，，6： | 1 |
| 13 | Effects of inutero tributyhin chloride exposure in the rat on pregnancy outcome 显示文摘 | Adedayo A Darning L Don S | 2003 | Toxieol Sci2003，74，： | 1 |
| 14 | Breast cancer subtypes based on ER/PR and HER-2 expression:Comparison of clinicopathologic features and survival显示文摘 | Adedayo A Onitilo Jessica M Engel Robert T | 2009 | Clin Med & Res2009，7，12： | 1 |
| 15 | Level of polycyclic aromatic hydrocarbon emission in the ambient air and residual ash from a typical municipal solid waste open burning site in Nigeria显示文摘Open burning of municipal solid waste(MSW)is a common practice in Nigeria.Emission of compounds of polycyclic aromatic hydrocarbon(PAHs)in ambient air and ash residues from burning of these wastes pose a great danger to the environment.This study investigated the contribution of open burning of MSW to the levels of PAHs in ambient air and ash residues from the burning site.Ash samples were obtained from six sampling locations at a MSW burning site.Polyurethane foam passive samplers were used in collecting ambient air samples.Quantification of PAHs was carried out using GC-MS operated in selected ion monitoring mode.The trend of ambient concentration of PAHs was;ΣPAHs AS-A(4.023)>AS-B(3.798)>AS-D(3.468)>AS-C(3.288),while average concentration of PAHs in the ash was 6.12 mg/kg.Concentrations of PAHs in ash samples ranged from 5.69-6.34 mg/kg.Principal component analysis(PCA)showed that most of the PAHs in the ambient were from MSW combustion.The results obtained suggest that concerted effort of the government and the relevant stakeholders is required to safeguard the environment and humans from PAH pollution from open burning of MSW. | Olusola Adedayo Adesina Adeyinka Olumide Adesina Jamiu Adetayo Adeniran | 2020 | Waste Disposal and Sustainable Energy2020，2，2： | 1 |
| 16 | Tumor-related hyponatremia 显示文摘 | Adedayo A Onitilo M D MSCR FACP | 2007 | CM & R2007，5，4： | 1 |
| 17 | Quantitative Characterization of Polymer-Polymer,Protein-Protein,and Polymer-Protein Interaction via Tracer Sedimentation Equilibrium 显示文摘 | Adedayo A Fodeke Allen P | 2010 | J Phys Chem B2010，114，10： | 1 |
| 18 | Breast cancer subtypes based on ER/PR and her2 expression: comparison of clinicopathologicfeatures and survival 显示文摘 | Adedayo A Onitilo MD | 2009 | Clin Med Res2009，7，1： | 1 |
| 19 | Effects of in utero tributyltin chloride exposure in the rat on pregnancy outcome显示文摘 | Adedayo A Daming L Don S | 2003 | Toxicological Science2003，74，： | 1 |
| 20 | Diabetes and cancer II: role of diabetes medications and influence of shared risk factors显示文摘 | Adedayo Onitilo Jessica Engel Ingrid Glurich Rachel Stankowski Gail Williams Suhail Doi | 2012 | Cancer Causes & Control2012，，7： | 1 |
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