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| 1 | Chronic peripheral inflammation: a possible contributor to neurodegenerative diseases显示文摘The contribution of chronic peripheral inflammation to the pathogenesis of neurodegenerative diseases is an outstanding question. Sustained activation of the peripheral innate and adaptive immune systems occurs in the context of a broad array of disorders ranging from chronic infectious diseases to autoimmune and metabolic diseases. In addition, progressive systemic inflammation is increasingly recognized during aging. Peripheral immune cells could potentially modulate the cellular brain environment via the secretion of soluble molecules. There is an ongoing debate whether peripheral immune cells have the potential to migrate into the brain under certain permissive circumstances. In this perspective, we discuss the possible contribution of chronic peripheral inflammation to the pathogenesis of age-related neurodegenerative diseases with a focus on microglia, the resident immune cells of the brain parenchyma. | Patrick Süβ Addison J.Lana Johannes C.M.Schlachetzki | 2021 | Neural Regeneration Research2021，16，9： | 3 |
| 2 | Exponential in- creases of the brominated flame retardants, polybrominated diphenyl ethers, in the Canadian Arctic from 1981 to 2000 显示文摘 | Ikonomou M G Rayne S Addison R F | 2002 | Environmental Science & Technology2002，36，9： | 1 |
| 3 | Pyrophos-phateinhibits mineralization of osteoblast cultures by binding to-mineral,up - regulating osteopontin,and nhibiting alkaline phos-phatase activity显示文摘 | Addison WN Azari F S rensen ES | 2007 | J Biol Chem2007，282，15： | 1 |
| 4 | A novel nonlinear car-Following model显示文摘 | Addison P S Lowd J | 1998 | Chaos1998，8，4： | 1 |
| 5 | Type- 1I collagen markers in osteoarthritis:what do they indicate? 显示文摘 | Henrotin Y Addison S Kraus V | 2007 | Curr Opin Rheumatol2007，19，5： | 1 |
| 6 | Chaotic response of a short journal bearing 显示文摘 | Brown R D Drummond G Addison P S | 2000 | Proceedings of the IMECH E Part J Journal of Engineering Tribology2000，214，4： | 1 |
| 7 | Coagulation in severe closed head injury:Is empiric therapy war ranted显示文摘 | Addison K J of frey S Kat by RN | 1997 | Am Surg1997，63，2： | 1 |
| 8 | Methimazole and propylthiouracil equally cross the perfused human term placental lobule 显示文摘 | MORTIMER R H CANNELL G R ADDISON R S | 1997 | Clin Endocrinol Metab1997，82，9： | 1 |
| 9 | The use of ambulatory blood pressure monitoring in managing hypertension according to different treatment guidelines显示文摘 | Addison C Varney S'Coats A | 2001 | J Hum Hypertens2001，15，8： | 1 |
| 10 | Pyrophosphate inhibits mineralization of osteoblast cultures by binding to mineral,up-regulating osteopontin,and inhibiting alkaline phosphatase activity显示文摘 | Addison WN Azari F S?rensen ES | | 0，，21： | 1 |
| 11 | A non-fickian, particle-tracking diffusion model based on fractional Brownian motion显示文摘 | Addison P S Qu B Nisbet A | 1997 | International Journal for Numberical Methods in Fluids1997，，25： | 1 |
| 12 | The osmotic tissue expander:a 5-year expeience显示文摘 | Chummun S Addison P Stewart KJ | | 0，，12： | 1 |
| 13 | Exponential increases of the brominated flame retardants, polybrominated diphenyl ethers, in the Canadian Arctic from 1981 to 2000 显示文摘 | Ikonomou M G Rayne S Addison R F | 2002 | Environmental Science & Technology2002，36，9： | 1 |
| 14 | Type Ⅱ collagen markers in osteoarthritis:what do they indicale显示文摘 | Henrotin Y Addison S Kraus V | 2007 | Current Opinion in Rheo- matology2007，19，5： | 1 |
| 15 | TypeⅡcollagen markers inosteoarthritis:what do they indicate?显示文摘 | Henrotin Y Addison S Kraus V | 2007 | Curr Opin Rheumatol2007，19，5： | 1 |
| 16 | Fractal cracking of concrete: parameterization of spatial diffusion显示文摘 | Addison P S McKenzie W M C Ndumu A S Dougan L T Hunter R | 1999 | Journal of Engineering Mechanics1999，125，6： | 1 |
| 17 | A fast non-Fickian particle-tracking diffusion simulator and the effect of shear on the pollutant diffusion process显示文摘 | Addison P S Ndumu A S Qu B | 2000 | International Journal for Numerical Methods in Fluids2000，34，2： | 1 |
| 18 | Role of hexa valent chromium in the inhibition of corrosion of aluminum alloys显示文摘 | Kendig M Jeanjaquet S Addison R | 2001 | Surface and Coatings Technology2001，140，1： | 1 |
| 19 | Non-Fickian,particle-tracking diffusion model based on fractional brownian motion显示文摘 | ADDISON P S QU B NISBET A | 1997 | International Journal for Numerical Methods in Fluids1997，25，： | 1 |
| 20 | A non-Fickian, particle-tracking diffusion model based on fractional Brownian motion 显示文摘 | ADDISON P S QU Bo NISBET A | 1997 | Intemational Journal for Numerical Methods in Fluids1997，25，： | 1 |
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