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| 1 | Endoscopic management of Crohn's strictures显示文摘Symptomatic intestinal strictures develop in more than one third of patients with Crohn's disease(CD) within 10 years of disease onset. Strictures can be inflammatory, fibrotic or mixed and result in a significant decline in quality of life, frequently requiring surgery for palliation of symptoms. Patients under the age of 40 with perianal disease are more likely to suffer from disabling ileocolonic disease thus may have a greater risk for fibrostenotic strictures. Treatment options for fibrostenotic strictures are limited to endoscopic and surgical therapy. Endoscopic balloon dilatation(EBD) appears to be a safe, less invasive and effective alternative modality to replace or defer surgery. Serious complications are rare and occur in less than 3% of procedures. For non-complex strictures without adjacent fistulizaation or perforation that are less than 5 cm in length, EBD should be considered as first-line therapy. The aim of this review is to present the current literature on the endoscopic management of small bowel and colonic strictures in CD, which includes balloon dilatation, adjuvant techniques of intralesional injection of steroids and anti-tumor necrosis factor, and metal stent insertion. Short and long-term outcomes, complications and safety of EBD will be discussed. | Talat Bessissow Jason Reinglas Achuthan Aruljothy Peter L Lakatos Gert Van Assche | 2018 | World Journal of Gastroenterology2018，24，17： | 10 |
| 2 | Risk factors of non-alcoholic fatty liver disease in patients with inflammatory bowel disease显示文摘 | Achuthan Sourianarayanane Gaurav Garg Thomas H. Smith Mujtaba I. Butt Arthur J. McCullough Bo Shen | 2013 | Journal of Crohn’s and Colitis2013，，8： | 2 |
| 3 | Diffusion tensor imaging pipeline measures of cerebral white matter integrity: An overview of recent advances and prospects显示文摘Cerebral small vessel disease(CSVD)is a leading cause of age-related microvascular cognitive decline,resulting in significant morbidity and decreased quality of life.Despite a progress on its key pathophysiological bases and general acceptance of key terms from neuroimaging findings as observed on the magnetic resonance imaging(MRI),key questions on CSVD remain elusive.Enhanced relationships and reliable lesion studies,such as white matter tractography using diffusion-based MRI(dMRI)are necessary in order to improve the assessment of white matter architecture and connectivity in CSVD.Diffusion tensor imaging(DTI)and tractography is an application of dMRI that provides data that can be used to non-invasively appraise the brain white matter connections via fiber tracking and enable visualization of individual patient-specific white matter fiber tracts to reflect the extent of CSVD-associated white matter damage.However,due to a lack of standardization on various sets of software or image pipeline processing utilized in this technique that driven mostly from research setting,interpreting the findings remain contentious,especially to inform an improved diagnosis and/or prognosis of CSVD for routine clinical use.In this minireview,we highlight the advances in DTI pipeline processing and the prospect of this DTI metrics as potential imaging biomarker for CSVD,even for subclinical CSVD in at-risk individuals. | Amanina Ahmad Safri Che Mohd Nasril Che Mohd Nassir Ismail Nurul Iman Nur Hartini Mohd Taib Anusha Achuthan Muzaimi Mustapha | 2022 | World Journal of Clinical Cases2022，10，24： | 2 |
| 4 | Sol-gel synthesis of PZT-glass nanocomposites using a simple sys- tem and characterization显示文摘 | Kumar V Asha T Achuthan Sivanandan K | 2006 | Int J Appl Ceram Techn2006，3，5： | 1 |
| 5 | An improved branch-and-cut algorithm for the capacitated vehicle routing problem显示文摘 | Achuthan N Caccetta L Hill S | 2003 | Transportation Science2003，37，2： | 1 |
| 6 | Colony stimulating factors and myeloid cell biology in health and disease显示文摘 | Hamilton JA Achuthan A | 2013 | Trend Immunol2013，34，： | 1 |
| 7 | Wavelet energy guided level set-based active contour: a segmentation method to segment highly similar regions显示文摘 | Achuthan A Rajeswari M Ramachandram D | 2010 | Computers in Bi-ology and Medicine2010，40，7： | 1 |
| 8 | On the vehicle routing problem 显示文摘 | ACHUTHAN N R CACCETTA L HILL S P | 1997 | Nonlinear Analysis1997，30，7： | 1 |
| 9 | Backbone structure amantadine-blocked trans-membrane domain M2 channel from influenza A virus 显示文摘 | Hu J of the proton 2007 Asbury T Achuthan S | 2007 | Biophys J2007，92，43： | 1 |
| 10 | Immobi-lization of nitrifying bacterial consortia on wood particles forbioaugmenting nitrification in shrimp culture systems显示文摘 | MANJU N J DEEPESH V ACHUTHAN C | 2009 | Aquaculture2009，294，12： | 1 |
| 11 | The IntAct molecular interaction database in 2010显示文摘 | Aranda B Achuthan P Alam-Faruque Y | | 0，，1： | 1 |
| 12 | Defining GM-CSF-and macrophage-CSF-dependent macrophage responses by in vitromodels显示文摘 | Lacey DC Achuthan A Fleetwood AJ | 2012 | J Immunol2012，188，11： | 1 |
| 13 | Antioxidative Potential of Lactobacilli Isolated From the Gut of Indian People显示文摘 | Achuthan Anju A Duary Raj Kumar Madathil Anupama | 2012 | Molecular Biology Reports2012，39，8： | 1 |
| 14 | On the number of cut edges in a regular graph显示文摘 | Achuthan N and Rao A R | 2003 | Australasian Journal of Combinatorics2003，，27： | 1 |
| 15 | Antioxidative potential of Lactobacilli isolated from the gut of In- dian people显示文摘 | Achuthan A A Duary R K Madathil A | 2012 | Molecular Biology Reports2012，39，8： | 1 |
| 16 | 显示文摘 | | 1990 | Propellants Explosives Pyrotechnics1990，15，： | 1 |
| 17 | Single Ascending Dose Safety and Pharmacokinetics of CDRI-97/78: First-in-Human Study of a Novel Antimalarial Drug显示文摘 | N. Shafiq S. Rajagopalan H. N. Kushwaha N. Mittal N. Chandurkar A. Bhalla S. Kaur P. Pandhi G. D. Puri S. Achuthan A. Pareek S. K. Singh J. S. Srivastava S. P. S. Gaur S. Malhotra Neena Valecha | 2014 | Malaria Research and Treatment2014，，： | 1 |
| 18 | Colony stimulating factors and myeloid cell biology in health and disease 显示文摘 | Hamilton JA Achuthan A | 2013 | Trends Immunol2013，34，2： | 1 |
| 19 | Immobilization of nitrifying bacterial consortia on wood par ticles for bioaugmenting nitrification in shrimp culture systems显示文摘 | Manju N J Deepesh V Achuthan Cini | 2009 | Aquaculture2009，，294： | 1 |
| 20 | Defining GM-CSF-and macrophage-CSF-dependent macrophage responses by in vitromodels显示文摘 | Lacey DC Achuthan A Fleetwood AJ | 2012 | J Immunol2012，188，11： | 1 |
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