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| 1 | Ultrasound biomicroscopic evaluation of anterior segment cysts as a risk factor for ocular hypertension and closure angle glaucoma显示文摘AIM:To investigate the relationship between the ultrasound biomicroscopic(UBM) features of anterior-segment cysts(ASCs) and increased intraocular pressure(IOP) as a risk factor for closed-angle glaucoma(CAG).·METHODS:Totally 24 eyes with recently diagnosed ASCs were divided into two groups.First group with ASC and ocular normotension(n =13),second group with ASC and ocular hypertension(n =11).An ophthalmologic examination,including tonometry,slit-lamp biomicro-scopy(SLBM),gonioscopy,fundoscopy,pentacam,and UBM,was performed.The features of the ASCs were compared with the IOP.·RESULTS:ASCs were accurately diagnosed and delineated in 24 eyes using UBM.IOP was elevated in those ASCs with a secondary aetiology(P =0.027),iridociliary location(P =0.006),deformed shape(P =0.013),increased size(P =0.001) and elongated pupillary aperture(P =0.009).However,the count(P =0.343) of ASCs,anterior chamber depth(ACD;P =0.22) and axial lenght(AL;P =0.31) were not associated with ocular hypertension.Correlations were found between the IOP and ASC size(r =-0.712;P =0.003),anterior chamber angle(ACA;r =-0.985;P <0.001),angle opening area(AOA;r =0.885;P<0.001),angulation of iris(r =-0.776,P <0.001),and affected iris quadrant(r =-0.655,P =0.002).·CONCLUSION:Ocular hypertension in some eyes with ASC might be associated with various mechanisms,including secondary aetiology,iridociliary location,deformed shape,increased size and elongated pupill,which can be determined by UBM. | Abdurrahim Dusak Mehmet Baykara Guven Ozkaya Cuneyt Erdogan Hikmet Ozcetin Ercan Tuncel | 2013 | International Journal of Ophthalmology(English edition)2013，6，4： | 3 |
| 2 | Relationship between diabetic polyneuropathy, serum visfatin, and oxidative stress biomarkers显示文摘BACKGROUND Diabetic polyneuropathy is a very common complication of diabetes.Numerous studies are available in terms of pathogenesis.But examination methods with low reliability are still not standardized and generally time consuming.Highsensitive,easy-to-access methods are expected.Biochemical markers are one of the subjects of research.We aimed to discover a potential biomarker that can be used for this purpose in patients with diabetes who have not yet developed symptoms of neuropathy.AIM To determine the place and availability of visfatin and thiol-disulfide homeostasis in this disorder.METHODS A total of 392 patients with type 2 diabetes mellitus were included in the study.The polyneuropathy clinical signs were evaluated with the Subjective Peripheral Neuropathy Screen Questionnaire and Michigan Neuropathy Screening Instrument questionnaire and examination.The biochemical parameters,oxidative stress markers,visfatin,and thiol-disulfide homeostasis were analyzed and correlated with each other and clinical signs.RESULTS Subjective Peripheral Neuropathy Screen Questionnaire and Michigan Neuropathy Screening Instrument questionnaire with examination scores were correlated with each other and diabetes duration(P<0.005).Neuropathy related symptoms were present in 20.7%of the patients,but neuropathy related findings were observed in 43.9%of the patients.Serum glucose,glycated hemoglobin,and visfatin were positively correlated with each other.Also,these parameters were positively correlated with the total oxidative stress index.Total and native thiol was positively correlated with total antioxidant status and negatively with oxidant status.Inversely thiol-disulfide positively correlated with higher glucose and oxidant status and negatively with total antioxidant status(P<0.005).There was no correlation between visfatin and thiol-disulphide(P=0.092,r=0.086).However,a significant negative correlation was observed between visfatin and total with native thiol(P<0.005,r=-0.338),(P<0.005,r=-0.448).CONCLUSION Diagnosis of neuropathy is one of the issues studied in patients with diabetes.Visfatin and thiol-disulfide balance were analyzed for the first time in this study with inspiring results. | Banu Buyukaydin Eray Metin Guler Tahsin Karaaslan Atilla Olgac Mehmet Zorlu Muharrem Kiskac Abdurrahim Kocyigit | 2020 | World Journal of Diabetes2020，11，7： | 2 |
| 3 | Cytotoxic, genotoxic and apoptotic effects of naringenin-oxime relative to naringenin on normal and cancer cell lines显示文摘Objective: To assess and compare the cytotoxic, genotoxic, apoptotic and reactive oxygen species(ROS) generating effects of naringenin(NG) and its new derived compound naringenin-oxime(NG-Ox) on MCF-7, HT-29, PC-12 cancer and L-929 normal cell lines.Methods: The cells were incubated with different doses of NG-Ox and NG(50–1 000 mmol/L) for 24 h. The cell viability was assessed based on ATP cell viability assay.Intracellular accumulation of ROS was determined using the fluorescent probes 2070-dichlorodihydrofluorescin diacetate. Genotoxic effects were evaluated by alkaline single cell gel electrophoresis assay(comet assay) and, the apoptotic effect was evaluated by acridine orange staining at below the IC50 levels.Results: Both NG-Ox and NG exhibited cytotoxic, genotoxic and apoptotic effects and resulted in increased ROS values in a dose-dependent manner. The effects were more pronounced on cancer cell lines. The cytotoxic, genotoxic and apoptotic effects of NG-Ox were higher than that of NG in all cell lines. Significant correlations were observed between cell viability, DNA damage, apoptosis and ROS, in all cell lines exposed to either NG-Ox or NG.Conclusions: This study showed that both NG-Ox and NG possess cytotoxic, genotoxic and apoptotic activities through the production of ROS on cells, NG-Ox being the more effective one. Therefore, derived compound of NG might be used as antiproliferative agents for the treatment of cancer. | Abdurrahim Kocyigit Ismail Koyuncu Murat Dikilitas Fatemeh Bahadori Baki Turkkan | 2016 | Asian Pacific Journal of Tropical Biomedicine2016，6，10： | 2 |
| 4 | Lymphocyte DNA damage and oxidative stress in patients with iron deficiency anemia 显示文摘 | Mehmet Aslan Mehmet Horoz Abdurrahim Kocyigit | 2006 | Mutation Research2006，601，1： | 1 |
| 5 | Intranasal 17 13-estradiol treatment and Vitamin B12 , folate and homo- cysteine in menopause 显示文摘 | Harma M Harma M Abdurrahim K | 2005 | Maturitas2005，50，4： | 1 |
| 6 | Deficit irrigation of sunflower (Helianthus annuus L.) in a sub-humid climate显示文摘 | Ali Osman Demir Abdurrahim Tanju G?ksoy Hakan Büyükcangaz Zeki Metin Turan Eyüp Selim K?ksal | 2006 | Irrigation Science2006，，4： | 1 |
| 7 | Graphene/polyethylene nanocomposites:effect of polyethylene functionalization and blending methods显示文摘 | Kim H Kobayashi S AbdurRahim M A | 2011 | Polymer2011，52，8： | 1 |
| 8 | Phototherapy causes DNA damage in peripheral mononuclear leukocytes in term infants显示文摘 | Ali A Abdurrahim K Ozcan E | 2008 | J Pediatr (Rio J)2008，84，2： | 1 |
| 9 | Soybean seed yield performances under different cultural practices 显示文摘 | Mehmet S Abdurrahim T G Zeki M T | 2009 | Turkish Journal of Agriculture and Forestry2009，33，8： | 1 |
| 10 | Breast milk provides better antioxidant power than does formula显示文摘 | Ali Aycicek Ozcan Erel Abdurrahim Kocyigit | 2006 | Nutrition2006，，22： | 1 |
| 11 | Effect of tobacco smoking on plasma selenium, zinc, copper and iron concentra- tions and related antioxidative enzyme activities 显示文摘 | Abdurrahim K Ozcan E Selahattin G | 2001 | Clinical Biochemistry2001，34，： | 1 |
| 12 | Increased DNA damage in patients with chronic obstructive pulmonary disease who had once smoked or been exposed to biomass 显示文摘 | Erkan Ceylan Abdurrahim Kocyigit Mehmet Gencer | 2006 | Respiratory Medicine2006，100，： | 1 |
| 13 | Intranssal 17β-estradiol treatment and Vitamin B12,folate and homocysteine in menopause显示文摘 | Muge Harma Mehmet Harma Abdurrahim K | 2005 | Maturitas2005，50，4： | 1 |
| 14 | Relationship between DNA damage, total antioxidant capacity and coronary artery disease显示文摘 | Recep Demirbag Remzi Yilmaz Abdurrahim Kocyigit | 2004 | Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis2004，，2： | 1 |
| 15 | The Quenching Behavior of Aqueous Nanofluids Around Rods with High Temperature显示文摘 | C Dogan B Abdurrahim | 2011 | Nuclear Engineering and Design2011，241，： | 1 |
| 16 | Assessment and Analysis of Rockfall-Caused Tree Injuries in a Turkish Fir Stand:A Case Study from Kastamonu-Turkey显示文摘Rockfalls can cause serious damage to people,property,facilities and transportation corridors.Furthermore,rockfalls are major hazards in mountain areas with negative impacts on individual trees and forested ecosystems.We conducted a study of rockfall events on 117 mapped(91% of total trees in the stand with>1.3 m in height and>5 cm diameter at breast height)Turkish fir trees(Abies bornmuelleriana Mattf.)in a stand within the Kayaarkasi-Topular Village,Inebolu district, Kastamonu province of Turkey.The study site of 0.35 Ha is located on the transition zone of frequently passing rockfall fragments(~40 cm in diameter) generally causing healable injuries.Parameters of trees and injuries were recorded and analysed as to injury number,height and size.Bivariate correlation analysis were used to investigate the relationships between:a)diameter at breast height and number of injuries per tree,b)diameter at breast height and total injury size,c)the number of injuries and total injury size and d)the number of injuries per tree and distance from the source of the rockfall area.Results indicate that the average height of injury,average number of injuries and average injury area to be 81.3 cm(STDEV:49.8),7.46(STDEV:4.4)and 628.6 cm2 (STDEV:678.2),respectively.In total 84% of all injuries were recorded within 160°sector at the upslope side of trees and callus tissue that had closed wounds was observed in 79.1% of all injuries. Furthermore 14.5% of injured trees had callus tissue in the process of closing wounds while 6.4% of injuries had not formed any callus tissue.The most common injury types were bark and wood injuries. Bivariate correlation analysis indicated strong relationships between diameter at breast height and the number of injuries(rs=0.524),injury number and total injury area(rs=0.653)and distance from rockfall area and injury numbers relations(rs=-0.518).A weaker relationship was found between diameter at breast height and total injury area(rs=0.363).These results indicate that bigger trees are more prone to rockfall injuries.As expected,trees further from the rockfall area seem to be less prone to rockfall injuries.From our results,it can be inferred that the protection of people and property can be increased through the maintanance of forest in areas immediately below areas prone to rockfall.This stand is still managed in selective forest management system.In order to protect the settlement at the deposition zone it has to manage for protective goals with uneven-aged and multilayered stand structure. | Abdurrahim AYDIN Nesibe KSE nal AKKEMK Hüseyin YURTSEVEN | 2012 | Journal of Mountain Science2012，9，2： | 0 |
| 17 | Effect of undulators on the stored electron beam of Indus-2显示文摘Indus-2 is an Indian synchrotron light source, operating at 2.5 Ge V and generating synchrotron radiation from its bending magnets. In order to provide more intense synchrotron radiation to the synchrotron users, there is a plan to install five insertion devices in the Indus-2 storage ring. In the first phase of installation of insertion devices, there is a proposal to install two out- vacuum pure permanent magnet linearly polarized undulators in long straight sections of the Indus-2 storage ring. The presence of the insertion devices in the ring has inevitable effects on beam parameters like betatron tune, betatron amplitude function, closed orbit, emittance, energy spread and dynamic aperture etc. In this paper, the effect of two undulators on the above mentioned parameters of the Indus-2stored electron beam at 2.5 Ge V is presented. Moreover a correction scheme for the restoration of the betatron tune and amplitude function is also presented. | Abdurrahim A.D.Ghodke | 2015 | Chinese Physics C2015，39，7： | 0 |
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