|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Hepatitis E virus: Epidemiology, diagnosis, clinical manifestations, and treatment显示文摘The hepatitis E virus(HEV)is the fifth known form of viral hepatitis and was first recognized as the cause of an epidemic of unexplained acute hepatitis in the early 1980s.Globally,it is one of the most frequent causes of acute viral hepatitis.The majority of HEV infections are asymptomatic and lead to the spontaneous clearance of the virus.Among the eight different genotypes identified to date,HEV genotype 1(HEV1),HEV2,HEV3,and HEV4 are the most frequent genotypes causing infections in humans.HEV1 and HEV2 are prevalent in developing regions and able to result in large-scale outbreaks originating from contaminated water supplies.They are also responsible for severe hepatitis in pregnant patients and infants.In contrast,HEV3 and HEV4 are zoonotic,and the transmission of these genotypes to humans occurs mainly through the fecal contamination of water and consumption of contaminated meat from infected animals.Their main reservoir is the pig,and they are mostly encountered in developed countries.The major risk groups for HEV infection and its ensuing adverse consequences are pregnant women,infants,older people,immunocompromised individuals,patients with underlying chronic liver diseases,and workers that come into close contact with HEV-infected animals.In the clinical perspective,HEV infections have diverse clinical manifestations including acute and self-limiting hepatitis,acute-on-chronic liver disease,chronic hepatitis,cirrhosis,and liver failure.Although HEV mainly results in acute selflimiting infection,chronic HEV infection may occur among immunocompromised patients(e.g.,solid-organ transplant recipients).Additionally,HEV-associated extrahepatic manifestations involving various organs have been reported in the last decade,although the causal link for many of them still needs to be proven.Ribavirin and interferon-alpha are the most widely used agents for the treatment of HEV infections with a certain level of success.However,ribavirin is contraindicated in pregnant patients,and interferon-alpha cannot be used in most transplant recipients.Therefore,there is an urgent need for novel antiviral compounds that are safe and effective particularly for patients having contraindications for ribavirin or interferon-alpha and infected by the ribavirinresistant HEV.In this review article,a literature search using PubMed and MEDLINE databases was performed,up to March 2020.Only the articles published in English were reviewed. | Abdullah Tarık Aslan Hatice Yasemin Balaban | 2020 | World Journal of Gastroenterology2020，26，37： | 15 |
| 2 | Batch kinetics of nitrogen and phosphorus removal from synthetic wastewater by algae显示文摘 | ASLAN S KAPDAN I K | 2006 | Ecological Engineering2006，28，1： | 1 |
| 3 | Tunable plasmonic glucose sensing based on the dissociation of Con A-aggregated dextran-coated gold colloids显示文摘 | ASLAN K LAKOWICZ J R GEDDES C D | 2004 | Anal Chim Acta2004，517，12： | 1 |
| 4 | Prenatal diagnosis of an ex-tralobar pulmonary sequestration显示文摘 | Yildirim G GUngbrdtik K Aslan H | 2008 | Arch Gynecol 0bstet2008，278，2： | 1 |
| 5 | Analysis of 3 776 pediatric inguinal hernia and hydrocele cases in a tertiary center显示文摘 | ERDOGAN D KARAMAN I ASLAN M K | 2013 | J Pediatr Surg2013，48，8： | 1 |
| 6 | Substrate consumption rates for hydrogen production by rhodobacter spharoides in a colun photobioreactor显示文摘 | Eroglu I Aslan k Gunduz U Yucel | 1999 | J of Biotechnology1999，70，： | 1 |
| 7 | The effect of antiepileptic drugs on vitamin B12 metabolism显示文摘 | Aslan K Bozdemir H Unsal C | 2008 | Int J Lab Hematol2008，30，1： | 1 |
| 8 | T-wave alternans in LQTS:Repolarization-rate dynamics from digital 12-lead Holter data显示文摘 | BROCKMEIER K ASLAN I HILBEL T | 2001 | J Electrocardiol2001，，： | 1 |
| 9 | Lipid and protein oxidation and antioxidant status in patients with angiographically proven coronary artery disease显示文摘 | Serdar Z Aslan K Dirican M | 2006 | Clin Biochem2006，39，8： | 1 |
| 10 | Limbal relaxing incisions in congenital astigmatism 6 month follow-up 显示文摘 | Budak K Yilmaz G Aslan BS | 2001 | J Cataract Refract Surg2001，27，1： | 1 |
| 11 | Can a b value of 500 be substi- tuted for a b value of 1000 in the characterization of focal liver le- sions? 显示文摘 | Aslan K Danaci M Polat AV | 2014 | Abdom Imaging2014，39，： | 1 |
| 12 | Overview of the Social I- impact of Urinary Incontinence with a Focus on Turkish Women显示文摘 | Beji N K Ozbas A Aslan E | 2010 | Urologic Nursing2010，30，6： | 1 |
| 13 | Metal-enhanced S-2 fluorescence from azulene显示文摘 | Zhang Y X Aslan K Previte M J R | | 0，，4： | 1 |
| 14 | 3-T MRI of the biliary tract variations显示文摘 | Hakan ?nder Muhammed S?dd?k ?zdemir Güven Tekba? Faysal Ekici Hatice Gümü? Aslan Bilici | 2013 | Surgical and Radiologic Anatomy2013，，2： | 1 |
| 15 | Some metri indices for the assessment of land consolidation projects显示文摘 | Aslan S T A Gundogdu K S Arici I | 2007 | Pakistan Journal of Biological Science2007，10，9： | 1 |
| 16 | The impact responses and the finite element modeling of layered trapezoidal corrugated aluminum core and aluminum sheet interlayer sandwich structures显示文摘 | Cenk K?l??aslan Mustafa Güden ?smet Kutlay Odac? Alper Ta?demirci | 2013 | Materials and Design2013，，： | 1 |
| 17 | No Inhibitory Deficit in Older Adults' Episodic Memory显示文摘 | Aslan A Baum K Past (o)tter B | | 0，，18： | 1 |
| 18 | Metal-enhanced fluorescence solution-based sensing platform显示文摘 | Aslan K Lakowicz J R Szmacinski H | 2004 | J Fluorescence2004，14，6： | 1 |
| 19 | Multidisciplinary approach in cystic hygroma:prenatal diagnosis,outcome,and postnatal follow up显示文摘 | Gedikbasi A Oztarhan K Aslan G | 2009 | Pediatr Iut2009，51，5： | 1 |
| 20 | Fluorescent core-shell Ag and SiO2 nanocomposites for metal-enhanced fluorescence and single nanoparticle sensing platforms显示文摘 | Aslan K Wu M Lakowicz J R | 2007 | J Am Chem Soc2007，129，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员