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| 1 | Trends and outcomes of pancreaticoduodenectomy for periampullary tumors: A 25-year single-center study of 1000 consecutive cases显示文摘AIM To evaluate the evolution, trends in surgical approaches a n d r e c o n s t r u c t i o n t e c h n i q u e s, a n d i m p o r t a n t lessons learned from performing 1000 consecutive pancreaticoduodenectomies(PDs) for periampullary tumors.METHODS This is a retrospective review of the data of all patients who underwent PD for periampullary tumor during the period from January 1993 to April 2017. The data were categorized into three periods, including early period(1993-2002), middle period(2003-2012), and late period(2013-2017).RESULTS The frequency showed PD was increasingly performed after the year 2000. With time, elderly, cirrhotic and obese patients, as well as patients with uncinate process carcinoma and borderline tumor were increasingly selected for PD. The median operative time and postoperative hospital stay decreased significantly over the periods. Hospital mortality declined significantly, from 6.6% to 3.1%. Postoperative complications significantly decreased, from 40% to 27.9%. There was significant decrease in postoperative pancreatic fistula in the second 10 years, from 15% to 12.7%. There was a significant improvement in median survival and overall survival among the periods.CONCLUSION Surgical results of PD significantly improved, with mortality rate nearly reaching 3%. Pancreatic reconstruction following PD is still debatable. The survival rate was also improved but the rate of recurrence is still high, at 36.9%. | ayman el nakeeb waleed askar ehab atef ehab el hanafy ahmad m sultan tarek salah ahmed shehta mohamed el sorogy emad hamdy mohamed el hemly ahmed a el-geidi tharwat kandil mohamed el shobari talaat abd allah amgad fouad mostafa abu zeid ahmed abu el eneen nabil gad el-hak gamal el ebidy omar fathy ahmed sultan mohamed abdel wahab | 2017 | World Journal of Gastroenterology2017，23，38： | 15 |
| 2 | Biliary leakage following pancreaticoduodenectomy:Prevalence,risk factors and management显示文摘Background: Few studies investigated biliary leakage after pancreaticoduodenectomy(PD) especially when compared to postoperative pancreatic fistula(POPF). This study was to determine the incidence of biliary leakage after PD, predisposing factors of biliary leakage, and its management. Methods: We retrospectively studied all patients who underwent PD from January 2008 to December 2017 at Gastrointestinal Surgery Center, Mansoura University, Egypt. According to occurrence of postoperative biliary leakage, patients were divided into two groups. Group(1) included patients who developed biliary leakage and group(2) included patients without identified biliary leakage. The preoperative data, operative details, and postoperative morbidity and mortality were analyzed. Results: The study included 555 patients. Forty-four patients(7.9%) developed biliary leakage. Ten patients(1.8%) had concomitant POPF. Multivariate analysis identified obesity and time needed for hepaticojejunostomy reconstruction as independent risk factors of biliary leakage, and no history of preoperative endoscopic retrograde cholangiopancreatiography(ERCP) as protective factor. Biliary leakage from hepaticojejunostomy after PD leads to a significant increase in development of delayed gastric emptying, and wound infection. The median hospital stay and time to resume oral intake were significantly greater in the biliary leakage group. Non-surgical management was needed in 40 patients(90.9%). Only 4 patients(9.1%) required re-exploration due to biliary peritonitis and associated POPF. The mortality rate in the biliary leakage group was significantly higher than that of the non-biliary leakage group(6.8% vs 3.9%, P = 0.05). Conclusions: Obesity and time needed for hepaticojejunostomy reconstruction are independent risk factors of biliary leakage, and no history of preoperative ERCP is protective factor. Biliary leakage increases the risk of morbidity and mortality especially if concomitant with POPF. However, biliary leakage can be conservatively managed in majority of cases. | Ayman El Nakeeb Mohamed El Sorogy Hosam Hamed Rami Said Mohamad Elrefai Helmy Ezzat Waleed Askar Ahmed M Elsabbagh | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，1： | 4 |
| 3 | Application of bit-level pipelining to delay insensitive null convention adders 显示文摘 | ISMAILOGLU A N ASKAR M | 2007 | Circuits and Systems2007，6，25： | 1 |
| 4 | Scott wiring for direct repair of lumbar spondylolysis显示文摘 | Wardlaw D Koti M | 2003 | Spine2003，28，4： | 1 |
| 5 | Scott wiring for direct repair of lumbar spondylolysis 显示文摘 | Askar Z Wardlaw D Koti M | 2003 | Spine ( Phila Pa 1976 )2003，25，4： | 1 |
| 6 | Large and ongoing outbreak of haemolytic uraemic syndrome, Germany, May 2011 显示文摘 | Frank C Faber MS Askar M | 2011 | Euro Surveill2011，，： | 1 |
| 7 | Lithium insertion into manganese dioxide polymorphs in aqueous electrolytes显示文摘 | Abou-El-Sherbini K S Askar M H | 2003 | Journal of Solid State Electrochemistry2003，7，7： | 1 |
| 8 | Evaluation of the hormones responsible for the gastrointestinal motility in cattle with displacement of the abomasum;ghrelin,motilin and gastrin显示文摘 | Ozturk AS Guzel M Askar TK | | 0，，24： | 1 |
| 9 | Evidence for airborne infectious disease transmission in public ground transport-a literature review 显示文摘 | Mohr O Askar M Schink S | 2012 | Euro Surveill2012，17，20： | 1 |
| 10 | Taylor expansion diagrams: acanonical representation fo r verification o f data flo w designs显示文摘 | Ciesielski M K alla P Askar S | 2006 | IEEE Transactions on Computers2006，55，9： | 1 |
| 11 | The protective effects of high dose ascorbic acid and diltiazem on myocardial ischaemia-reperfusion injury显示文摘 | DEMIRAG K ASKAR FZ UYAR M | 2001 | Middle East J Anesthesiol2001，16，： | 1 |
| 12 | Scott wiring for direct repair of lumbar spondylolysis显示文摘 | Askar Z Wardlaw D Koti M | 2003 | Spine2003，28，4： | 1 |
| 13 | Effects of heparin fractions on the prevention of skin necrosis resulting from adriamycin extravasation:an experimental study显示文摘 | ASKAR L ERBAS M K GURLEK A | 2002 | Ann Plast Surg2002，49，3： | 1 |
| 14 | Large and ongoing out- break of haemolytic uraemic syndrome, Germany, May 2011 显示文摘 | Frank C Faber M S Askar M | 2011 | Euro Surveill2011，16，21： | 1 |
| 15 | Predictions in the face of clinical reality:HistoCheck versus high-risk HLA allele mismatch combinations responsible for severe acute graftversus-host disease显示文摘 | Askar M Sobecks R Morishima Y | | 0，，9： | 1 |
| 16 | Large and ongoing outbreak of haemolytic uraemic syndrome 显示文摘 | FRANKC F M ASKAR M BERNARD H | 2011 | Eurosurveillance2011，16，21： | 1 |
| 17 | Scott wiring for direct repair of lumbar spondylolysis 显示文摘 | Askar Z Wardlaw D Koti M | 2003 | Spine2003，28，4： | 1 |
| 18 | On multi-team games显示文摘 | Ahmed E Hegazi A S Elettreby M F Askar S S | 2006 | Physica A2006，369，2： | 1 |
| 19 | Lithium Insertion into Manganese Dioxide Polymorphs in Aqueous Electrolytes 显示文摘 | Abou-EI-Sherbini K S Askar M H | 2003 | J Solid State Ionics2003，7，： | 1 |
| 20 | Osmotic and solar dehydration of peach fruits 显示文摘 | Askar A Abdel-Fadeel M G Ghonaim S M | 1996 | Fruit Process1996，9，1： | 1 |
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