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| 1 | Trends and outcomes of pancreaticoduodenectomy for periampullary tumors: A 25-year single-center study of 1000 consecutive cases显示文摘AIM To evaluate the evolution, trends in surgical approaches a n d r e c o n s t r u c t i o n t e c h n i q u e s, a n d i m p o r t a n t lessons learned from performing 1000 consecutive pancreaticoduodenectomies(PDs) for periampullary tumors.METHODS This is a retrospective review of the data of all patients who underwent PD for periampullary tumor during the period from January 1993 to April 2017. The data were categorized into three periods, including early period(1993-2002), middle period(2003-2012), and late period(2013-2017).RESULTS The frequency showed PD was increasingly performed after the year 2000. With time, elderly, cirrhotic and obese patients, as well as patients with uncinate process carcinoma and borderline tumor were increasingly selected for PD. The median operative time and postoperative hospital stay decreased significantly over the periods. Hospital mortality declined significantly, from 6.6% to 3.1%. Postoperative complications significantly decreased, from 40% to 27.9%. There was significant decrease in postoperative pancreatic fistula in the second 10 years, from 15% to 12.7%. There was a significant improvement in median survival and overall survival among the periods.CONCLUSION Surgical results of PD significantly improved, with mortality rate nearly reaching 3%. Pancreatic reconstruction following PD is still debatable. The survival rate was also improved but the rate of recurrence is still high, at 36.9%. | ayman el nakeeb waleed askar ehab atef ehab el hanafy ahmad m sultan tarek salah ahmed shehta mohamed el sorogy emad hamdy mohamed el hemly ahmed a el-geidi tharwat kandil mohamed el shobari talaat abd allah amgad fouad mostafa abu zeid ahmed abu el eneen nabil gad el-hak gamal el ebidy omar fathy ahmed sultan mohamed abdel wahab | 2017 | World Journal of Gastroenterology2017，23，38： | 15 |
| 2 | Collateral blood vessels in acute ischaemic stroke: a potential therapeutic target显示文摘 | Ashfaq Shuaib Ken Butcher Askar A Mohammad Maher Saqqur David S Liebeskind | 2011 | Lancet Neurology2011，，10： | 3 |
| 3 | Outcome and complications in peritoneal dialysis patients:a five-year single center experience显示文摘 | Alwakeel JS Alsuwaida A Askar A | 2011 | Saudi J Kidney Dis Transpl2011，22，2： | 1 |
| 4 | Application of bit-level pipelining to delay insensitive null convention adders 显示文摘 | ISMAILOGLU A N ASKAR M | 2007 | Circuits and Systems2007，6，25： | 1 |
| 5 | Effects of heparin fractions on theprevention ofskin necrosis resulting from adriamycin extravasation: An experimental study显示文摘 | Askar I Erbas MK Gurlek A | 2002 | Ann Plast Surg2002，49，3： | 1 |
| 6 | 显示文摘 | DEY B K ASKAR A RABITZ H A | 1999 | J Chem Phys1999，109，20： | 1 |
| 7 | Effect of time delay on control of seismic-excited buildings显示文摘 | Yang J N Akbarpour A Askar G | 1990 | Journal of Structural Engineering ASCE1990，116，10： | 1 |
| 8 | Immediate clinical outcome after prolonged periods of brain protection retrospective comparison of hypothermic circularory arrest,retrograde,and antegrade perfusion显示文摘 | Apaydin A Z Islamoglu F Askar F Z | 2009 | J Card Surg2009，24，5： | 1 |
| 9 | Exposure of high-density porous polyethylene (Medpor) used for contour restoration and treatment显示文摘 | SEVIN K ASKAR I SARAY A | 2000 | Br J Oral Maxillofae Surg2000，38，1： | 1 |
| 10 | Recombinant activated factor Ⅶ treatment of retroperitoneal hematoma in a patient with renal failure receiving enoxaparin and clopidogrel 显示文摘 | CHERFAN A ARABI Y AL ASKAR A | 2007 | Pharmacotherapy2007，27，5： | 1 |
| 11 | Outcome and complications in peritoneal dialysis patients:A five-year single center experience显示文摘 | Alwakeel JS Alsuwaida A Askar A | 2011 | Saudi J Kidney Dis Transpl2011，22，2： | 1 |
| 12 | Cerebral salt wasting in a patient with head trauma:management with saline hydration and fludrocortisone显示文摘 | Askar A Tarif N | 2007 | Saudi J Kidney Dis Transpl2007，18，1： | 1 |
| 13 | About new possibilities of particles acceleration up to high energies显示文摘 | Askar'yan G A | 1973 | Trudy FIAN1973，，66： | 1 |
| 14 | Exposure of high-density porous polyethylene(Medpor)used for contour restoration and treatment显示文摘 | Sevin K Askar I Saray A | 2000 | Br J Oral Maxillofac Surg2000，38，1： | 1 |
| 15 | Outcome and eomplica-tio ns in peritoneal dialysis patients: A five- year single eenterex- prience显示文摘 | Alwakeel JS Alsuwaida A Askar A | 2011 | Saudi J Kidney Dis Transpl2011，22，2： | 1 |
| 16 | Effects of heparin fractions on the prevention of skin necrosis resulting from adriamycin extravasation :an experimental study显示文摘 | Askar I Erbas MK Gurlek A | 2002 | Ann Plast Surg2002，49，3： | 1 |
| 17 | Effects of heparin fractions on the prevention of skin necrosis resulting from adriamycin extravasation:an experimental study显示文摘 | ASKAR L ERBAS M K GURLEK A | 2002 | Ann Plast Surg2002，49，3： | 1 |
| 18 | Earthquake waves in a random medium显示文摘 | Chu L Askar A and Cakmak A S | 1981 | International Journal for Numerical and Analytic al Methods in Geomechanics1981，5，1： | 1 |
| 19 | Finite element method for bound state calculations in quantum mechanics显示文摘 | ASKAR A | 1975 | J Chem Phys1975，62，2： | 1 |
| 20 | Effects of heparinti actions on the prevention of skin necrosis resulting from adriamycin extravasations:an experimental study显示文摘 | Askar I Erbas MK Gurlek A | 2002 | Ann Plast Surg2002，49，3： | 1 |
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