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| 1 | Mechanical and cellular processes driving cervical myelopathy显示文摘Cervical myelopathy is a well-described clinical syndrome that may evolve from a combination of etiological mechanisms. It is traditionally classified by cervical spinal cord and/or nerve root compression which varies in severity and number of levels involved. The vast array of clinical manifestations of cervical myelopathy cannot fully be explained by the simple concept that a narrowed spinal canal causes compression of the cord, local tissue ischemia, injury and neurological impairment. Despite advances in surgical technology and treatment innovations, there are limited neuro-protective treatments for cervical myelopathy, which reflects an incomplete understanding of the pathophysiological processes involved in this disease. The aim of this review is to provide a comprehensive overview of the key pathophysiological processes at play in the development of cervical myelopathy. | Roisin T Dolan Joseph S Butler John M O'Byrne Ashley R Poynton | 2016 | World Journal of Orthopedics2016，7，1： | 5 |
| 2 | Skin-gut axis:The relationship between intestinal bacteria and skin health显示文摘The gut microbiome is an emerging area of interest in medicine. Imbalances in the gut microbiome have been linked to a number of disease states such as obesity and type 2 diabetes. The relationship between normally residing intestinal bacteria(the gut microbiota) and their potential role in the pathogenesis of skin diseases is an area of research for which we are only beginning to understand. Small studies have demonstrated underlying changes in the gut microbiome of patients with certain dermatological diseases. Interestingly, studies suggest that probiotics may have a role in the treatment of atopic dermatitis. However, the concept of the 'skin-gut axis' is a newly emerging and important avenue of investigation, still lacking in pathobiological explanations. This review will introduce and describe the intestinal microbiome as it relates to skin health in a complex communication network between the immune system, endocrine system, metabolic system, and nervous system. | Alexandra R Vaughn Manisha Notay Ashley K Clark Raja K Sivamani | 2017 | World Journal of Dermatology2017，6，4： | 4 |
| 3 | 2009年南极冰穹A的双色天光背景统计和分析显示文摘天光背景是天文台址的一个重要指标。利用2009年位于南极冰穹A的CSTAR望远镜两个波段的观测数据,对南极冰穹A的天光背景进行了统计和分析。结果表明约74%的g波段天光背景的ADU值小于每像素100/s;90.5%的r波段的天光背景的ADU值小于每像素100/s。在不考虑大气消光的情况下,定标后的结果为2009年冰穹A的观测数据中天光背景亮度的中值:g波段为19.9 mag/arcsec2,r波段为20.1 mag/arcsec2。 | 宗伟凯 付建宁 牛家树 Ashley Michael C B 宫雪非 Lawrence J S 刘强 Luong-Van Daniel Pennypacker C R Storey John W V 王灵芝 王力帆 杨惠根 袁祥岩 York Donald G 朱镇熹 | 2014 | 天文研究与技术2014，11，1： | 2 |
| 4 | Lung cancer screening: Should we be excluding people with previous malignancy?显示文摘The National Lung Screening Trial(NLST) was a large,randomized, controlled study showing a 20% reduction of lung cancer mortality and 7% reduction of all cause mortality using annual low dose computed tomography(LDCT) in a high risk population. NLST excluded people with a previous history of cancer treatment within the past 5 years and all people with a history lung cancer. The aim of this work is to review how lung cancer screening trials addressed the confounding effect of previous malignancy. We also review the subsequent recommendations by the United States Preventative Task Force Services, multiple professional societies and the Center for Medicaid and Medicare Services which defer either to NLST criteria or, clinician judgment or refrain from asserting any recommendation on the topic, respectively. Implications of lung cancer screening in the setting of previous malignancies, specifically lung, head and neck, esophageal, gastric, breast, colorectal cancer and lymphoma are also discussed. With lung cancer screening, an antecedent malignancy introduces the possibility of discovering metastasis as well as lung cancer. In some circumstances diagnosis and treatment of oligometastatic disease may confer a survival benefit. The survival benefit of treating either lung cancer or oligometastatic disease as result of lung cancer screening has yet to be determined. Further studies are needed to determine the role of lung cancer screening in the setting of previous malignancy. | Cherie P Erkmen Larry R Kaiser Ashley L Ehret | 2016 | World Journal of Respirology2016，6，1： | 2 |
| 5 | QTLs conditioning early growth in a soybean population segregation for growth habit 显示文摘 | Mian M A R Ashley D A Vencill WK et at | 1998 | Theoretical and Applied Genetics1998，97，8： | 1 |
| 6 | Sediment origins, deposition and build-up in combined sewer systems显示文摘 | ASHLEY R M CRABTREE R W | 1992 | Water Science & Technology1992，25，8： | 1 |
| 7 | A multi-plasmid approach to preparing large libraries of polyketides显示文摘 | Ashley G Hutchinson C R | 1999 | Proc Natl Acad Sci USA1999，96，11： | 1 |
| 8 | An additional QTL for water use efficiency in soybean显示文摘 | MAIN M A R ASHLEY D BAILEY M A | 1998 | Crop Sci1998，38，： | 1 |
| 9 | Melecularmarkers associated with water use efficiency and leafash in soybean显示文摘 | MIAN M A R BAILEY M A ASHLEY D D | 1996 | Crop Sci1996，36，： | 1 |
| 10 | Discrimination of hydrothermally altered rocks and unaltered rocks in visible and near infrared multi- spectral images显示文摘 | ROWAN L C GOETZ A F H ASHLEY R P | 1977 | Geophysics1977，42，3： | 1 |
| 11 | Urachal anomalies:a lon- gitudinal study of uraehal remnants in children and adults显示文摘 | Ashley R A Inman B A Routh J C | 2007 | JUrol2007，178，4： | 1 |
| 12 | The influence of near bed solids transport on first foul flush in combined sewers显示文摘 | ARTHUR S ASHLEY R | 1998 | Water Science & Technology1998，25，8： | 1 |
| 13 | Analysis of volatile organic compounds in mainstream cigarette smoke显示文摘 | Polzin G M Kosa-Maines R E Ashley D L | 2007 | Environmental Science & Technology2007，41，4： | 1 |
| 14 | Cultivar differences in canopy apparent photosynthesis and their relationship to seed yield in soybean显示文摘 | Wells R Schulze Ashley DA | 1982 | Crop Sei1982，22，： | 1 |
| 15 | Improving the safety of chemo- therapy administration:An oncology nurse failure mode and effects a- nalysis显示文摘 | Ashley L Dexter R Marshall F | 2011 | Oncol Nurs For2011，38，6： | 1 |
| 16 | Sequence and genome organization of a human small round-structured(Norwalk like)virus显示文摘 | Lambden P R Caul E O Ashley C R | 1993 | Science1993，259，5094： | 1 |
| 17 | Methods for Researching Gear Whine in Automotive TransaxIes显示文摘 | ASHLEY L D DONALD R H | 1997 | SAE1997，，1： | 1 |
| 18 | Double-blind,placebo-controlled trial of a herpes simplex virus type 2 glycoprotein vaccine in persons at high risk for genital herpes infection显示文摘 | MERTZ G J ASHLEY R BURKE R L | 1990 | J Infect Dis1990，161，4： | 1 |
| 19 | Evaluatian and competitive tendering of Laibin B power plant project in China 显示文摘 | Wang S Q Tiong R L K Ting S K Chew D and Ashley D | 1998 | Journal of Construction Engineering and Management1998，124，4： | 1 |
| 20 | Genetic architecture of artemisiuin-resistant Plasmodium folciparum 显示文摘 | Miotto O Amato R Ashley EA | 2015 | Nature ge- netics2015，47，3： | 1 |
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