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| 1 | The roles of MAPKs in disease显示文摘印射响应许多 ligands 和房间刺激涉及大量的细胞的小径和功能的家族 ases transduce 信号。MAPK 的异常或不恰当的功能现在在从癌症到煽动性的疾病到肥胖和糖尿病的疾病被识别了。在许多房间类型, MAPK ERK1/2 被连接到细胞增殖。因为在地岬和 B-Raf 的变化,能激活 ERK1/2 串联,在许多人的肿瘤被发现, ERK1/2 被认为在一些癌症起一个作用。发信号的反常 ERK1/2 也在 polycystic 肾疾病被发现了,并且象 cardio-facio-cutaneous 症候群那样的严肃的发展混乱在 ERK1/2 串联的部件从变化产生。ERK1/2 在区分得好的房间是必要的并且在神经原并且在上皮的极性的维护被连接了到长期的 potentiation。另外, ERK1/2 为在胰腺的贝它房间的胰岛素基因抄写是重要的,它响应传播葡萄糖的增加生产胰岛素在有机体允许有效葡萄糖利用和存储。导致或镇压的营养素和荷尔蒙胰岛素分泌物以在贝它房间上反映能分泌的需求的一种方式激活或禁止 ERK1/2。在这和另外的规章的小径的骚乱可以导致对某些人的混乱的病原学的 ERK1/2 的贡献。 | Michael C Lawrence Arif Jivan Chunli Shao Lingling Duan Daryl Goad Elma Zaganjor Jihan Osborne Kathleen McGlynn Steve Stippec Svetlana Earnest Wei Chen Melanie H Cobb | 2008 | Cell Research2008，18，4： | 64 |
| 2 | Handheld high-throughput plasmonic biosensor using computational on-chip imaging显示文摘We demonstrate a handheld on-chip biosensing technology that employs plasmonic microarrays coupled with a lens-free computational imaging system towards multiplexed and high-throughput screening of biomolecular interactions for point-of-care applications and resource-limited settings.This lightweight and field-portable biosensing device,weighing 60 g and 7.5 cm tall,utilizes a compact optoelectronic sensor array to record the diffraction patterns of plasmonic nanostructures under uniform illumination by a single-light emitting diode tuned to the plasmonic mode of the nanoapertures.Employing a sensitive plasmonic array design that is combined with lens-free computational imaging,we demonstrate label-free and quantitative detection of biomolecules with a protein layer thickness down to 3 nm.Integrating large-scale plasmonic microarrays,our on-chip imaging platform enables simultaneous detection of protein mono-and bilayers on the same platform over a wide range of biomolecule concentrations.In this handheld device,we also employ an iterative phase retrieval-based image reconstruction method,which offers the ability to digitally image a highly multiplexed array of sensors on the same plasmonic chip,making this approach especially suitable for high-throughput diagnostic applications in field settings. | Arif E Cetin Ahmet F Coskun Betty C Galarreta Min Huang David Herman Aydogan Ozcan Hatice Altug | 2014 | Light(Science & Applications)2014，3，1： | 6 |
| 3 | Force-displacement model foranalysis of pulsed-GMAW显示文摘 | Arif N Lee J H Yoo C D | 2009 | Journal of Physics D:AppliedPhysics2009，42，3： | 1 |
| 4 | Making a case for offsite construction in China 显示文摘 | ARIF M EGBU C | 2010 | Engineering Construction and Architectural Management2010，17，6： | 1 |
| 5 | Cemented carbide cutting tool: Laster processing and thermal stress analysis显示文摘 | YILBAS B S ARIF A F M KARATAS C AHSAN M | 2007 | Applied Surface Science2007，253，： | 1 |
| 6 | Modelling of globular transfer considering momentum flux in GMAW 显示文摘 | Arif N Lee J H Yoo C D | 2008 | Journal of Phys- ics D:Applied Physics2008，，41： | 1 |
| 7 | Phenacoccus solenopsis Tinsley (Sternorrhyncha: Coccoidea: Pseudococcidae), an invasive mealybuy damaging cotton in Pakistan and India,with a discussion on seasonal morphological variation显示文摘 | Hodgson C J Abbas G Arif M J | 2008 | Zootaxa2008，1913，： | 1 |
| 8 | Predominance of interaction among wild-type alleles of CYP11B2 in himalayan natives associates with high-altitude adaptation 显示文摘 | RAJPUT C ARIF E VIBHUTI A | 2006 | Bioehem Biophys Res Commun2006，348，2： | 1 |
| 9 | Synchronization and storage models for multimedia objects显示文摘 | Thomas D C Little Arif Ghafoor | 1990 | IEEE Journal on Selected Areas in Communications1990，8，3： | 1 |
| 10 | Decomposition and ignition of the high-nitrogen compound triamino-guanidinium azotetrazolate(TAGZT)显示文摘 | Bryce C T Arif N A Steven F S et al | 2006 | Propellants Explosives Pyrotechnics2006，31，3： | 1 |
| 11 | Metal-based antibacterial and antifungal amino acid derived Schiff bases: their synthesis, characterization and in vitro biological activity 显示文摘 | Zahid H C Arif M Sarfraz M | 2007 | Appl Organometal Chem2007，21，： | 1 |
| 12 | Antioxidant activity andproline content of leaf extracts from Dorystoechas hastate显示文摘 | Arife A K Bengi E Yelda C E | 2008 | Food Chemistry2008，111，： | 1 |
| 13 | Phenacoccus solenopsls Tinsley ( Stemorrhyncha: Coccoidea :Pseudoeoccidae), an invasive mealybug damaging cotton in Pakistan and India,with a discussion on seasorml monphological variation显示文摘 | HODGSON C ABBAS G ARIF M J | 2008 | Zootaxa2008，1913，： | 1 |
| 14 | Host rock characteristics and source of chromium and beryllium for emerald mineralization in the ophiolitic rocks of the Indus Suture Zone in Swat,NW Pakistan显示文摘 | Arif M Henry D J Moon C J | | 0，，： | 1 |
| 15 | Aggregate investment and investor sentiment显示文摘 | Arif S and Lee C M C | 2014 | Review of Financial Studies2014，27，11： | 1 |
| 16 | Race/ethnicity, income, chronic asthma, and mental health: a cross- sectional study using the behavioral risk factor surveillance system 显示文摘 | Bandiera F C Pereira D B Arif A A | 2008 | Psychosom Med2008，70，1： | 1 |
| 17 | A review of heat pump drying: Part 1-Systems, models and studies 显示文摘 | Neslihan C Arif H | 2009 | Energy Conversion and Management2009，50，： | 1 |
| 18 | Laser control melting of alumina surfaces and thermal stress analysis 显示文摘 | Yilbas B S Karatas C Arif A F M | 2011 | Optics and Laser Technology2011，43，： | 1 |
| 19 | The efficacy of Ankaferd Blood Stopper in antithrombotic drug-induced primary and secondary hemostatic abnormalities of a rat-bleeding model显示文摘 | Ali Kosar Handan S Cipil Arif Kaya Burak Uz Ibrahim C Haznedaroglu Hakan Goker Oktay Ozdemir Sevil Ercetin Serafettin Kirazli Huseyin Cahit Firat | 2009 | Blood Coagulation & Fibrinolysis2009，，3： | 1 |
| 20 | Phenacoccus solenopsis Tinsley ( Sternorrhyncha : Coccoiea : Pseudococcidae ) , an invasive mealybug damaging cotton in Pakistan and India, with a discussion on seasonal monphological variation 显示文摘 | Hodgson C Abbas G Arif M J | 2008 | Zootaxa2008，1913，： | 1 |
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