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| 1 | Combination Therapy With Infliximab and Azathioprine Is Superior to Monotherapy With Either Agent in Ulcerative Colitis显示文摘 | Remo Panaccione Subrata Ghosh Stephen Middleton Juan R. Márquez Boyd B. Scott Laurence Flint Hubert JF. van Hoogstraten Annie C. Chen Hanzhe Zheng Silvio Danese Paul Rutgeerts | 2013 | Gastroenterology2013，，： | 5 |
| 2 | Ly49 receptors activate angiogenic mouse DBA+ uterine natural killer cells显示文摘 | Patricia DA Lima Megan M Tu Mir Munir A Rahim Annie R Peng B Anne Croy Andrew P Makrigiannis | 2014 | Cellular & Molecular Immunology2014，11，5： | 3 |
| 3 | Pulse pressure and aortic pulse wave are markers of cardiovascular risk in hypertensive populations显示文摘 | Roland Asmar Annie Rudnichi Jacques Blacher Gérard M London Michel E Safar | 2001 | American Journal of Hypertension2001，，2： | 3 |
| 4 | 抑郁症的非药物治疗:系统性综述与证据图显示文摘背景抑郁症非药物治疗的疗效比较目前仍然不清楚。方法我们对一些系统性综述作了概述,回顾了随机对照试验(RCT),比较抑郁症非药物治疗的有效性和认知行为治疗(CBT)。对多个电子数据库在2016年2月之前发表的所有文献进行了检索,不限制语言。成对的评阅人进行资料纳入、数据提炼并评估偏倚的风险。在适用的时候进行了荟萃分析。结果我们收录了367项RCT,纳入了约2000名患者,进行了11种治疗,导出17项独立的头对头比较。通过标准化的量表评估,发现CBT、自然疗法、行为干预与躯体活动干预可以降低抑郁的严重程度。然而,这些非药物干预的相对疗效仍然缺乏。这些干预对临床缓解和复发的效果不清楚。CBT的发生率比抗抑郁药物更低。局限性由于证据缺乏一致性、证据不清或偏倚风险高,导致证据的质量只是低到中等,限制了我们研究结果的可信度。结论抑郁症的非药物治疗能减少抑郁症状,在轻度到重度抑郁症患者中,应当合并抗抑郁药物治疗,一同进行。对于非药物治疗的选择,应当根据患者的价值观、偏好、临床和社会因素来与患者共同作出决定。 | Wigdan H Farah Mouaz Alsawas Maria Mainou Fares Alahdab Magdoleen H Farah Ahmed T Ahmed Essa A Mohamed Jehad Almasri Michael R Gionfriddo Ana Castaneda-Guarderas Khaled Mohammed Zhen Wang Noor Asi Craig N Sawchuk Mark D Williams Larry J Prokop M Hassan Murad Annie LeBlanc | 2017 | 英国医学杂志中文版2017，20，11： | 2 |
| 5 | Disseminated intravascular coagulation associated with massive brain injury显示文摘 | Keimowitz R M Annis B L | 1973 | J Neurosurg1973，39，2： | 2 |
| 6 | Influence of donor age on the differentiation and division capacity of human adipose-derived stem cells显示文摘BACKGROUND Human adipose-derived stromal/stem cells(hASCs)are one of the most useful types of mesenchymal stromal/stem cells,which are adult multipotent cells with great therapeutic potential for the treatment of several diseases.However,for successful clinical application,it is critical that high-quality cells can be obtained.Diverse factors seem to be able to influence cell quality and performance,especially factors related to donors’intrinsic characteristics,such as age.Nevertheless,there is no consensus regarding this characteristic,and there is conflicting information in the literature.AIM To investigate the growth kinetics and differentiation potential of adipose-derived stem cells isolated from the lipoaspirates of elderly and young donors.METHODS hASCs were harvested from liposuctioned adipose tissue obtained from female donors(aged 20-70 years).Cells were distributed into two groups according to age range:old hASCs(oASCs,≥55 years,n=9)and young hASCs(yASCs,≤35 years,n=9).For each group,immunophenotypic characterization was performed by flow cytometry.Population doubling time was assessed over seven days.For adipogenic potential evaluation,lipid deposits were assessed after 7 d,14 d and 21 d of adipogenic induction.Osteogenic potential was verified by analyzing cell mineralization after 14 d,21 d and 28 d of osteogenic induction.mRNA expression of PPARγ2,CEBPA and Runx2 were detected by quantitative reverse transcription polymerase chain reaction.RESULTS hASCs were successfully obtained,cultured,and grouped according to their age:yASCs(26.33±4.66 years old)and oASCs(64.78±4.58 years old).After maintenance of the cells in culture,there were no differences in morphology between cells from the young and old donors.Additionally,both groups showed classical immunophenotypic characteristics of mesenchymal stem/stromal cells.The average doubling time indicated that yASCs(4.09±0.94 d)did not significantly differ from oASCs(4.19±1.29 d).Concerning differentiation potential,after adipogenic and osteogenic induction,yASCs and oASCs were able to differentiate to greater levels than the noninduced control cells.However,no differences were found in the differentiation efficiency of yASCs and oASCs in adipogenesis or osteogenesis.Additionally,the mRNA expression of PPARγ2,CEBPA and Runx2 were similar in yASCs and oASCs.CONCLUSION Our findings suggest that age does not seem to significantly affect the cell division or adipogenic or osteogenic differentiation ability of adipose-derived stem cells isolated from lipoaspirates. | Cintia DS Horinouchi María Julia Barisón Anny W Robert Crisciele Kuligovski Alessandra M Aguiar BrunoDallagiovanna | 2020 | World Journal of Stem Cells2020，12，12： | 2 |
| 7 | Hashash,Nonlinear Ground-Response Analysis of Turkey Flat Shallow Stiff-soil Site to Strong Ground Motion显示文摘 | Annie 0 L Kwok Jonathan P Stewart Youssef M A | 2008 | Bulletin ot' the Seis- mological Society of America February2008，98，： | 1 |
| 8 | Uhrafast Carrier Dynamics in Core and Core/shell CdSe Quantum Rods: Role of the Surface and Interface Defects 显示文摘 | CRETI A ANNI M ROSSI M Z | 2005 | Phys Rev B2005，72，： | 1 |
| 9 | Quantitative analysis offlavour precursors and pyruvate levels in different tissues and cultivars ofonion(Allium cepa)显示文摘 | JAMES R B GRAHAM K M ANNIE N | 1999 | Food Chemistry1999，64，2： | 1 |
| 10 | Column test investigation on the performance of monolayer covers made of desulphurized tailings to prevent acid mine drainage 显示文摘 | Demers I Bussiere B Benzaazoua M Mamert M Annie B | 2008 | Minerals Engineering2008，21，4： | 1 |
| 11 | 查看详情显示文摘 | Anni M Manna L Cingolani R Valerini D. Cretí A.Lomascolo M | | 0，，18： | 1 |
| 12 | Settlement preferences and early migration of the tropical sea cucumber Holothuria scabra显示文摘 | Annie M Stephen C Jean-Francois H | 2000 | J Exp Mar Bio Ecol2000，249，： | 1 |
| 13 | Myc potentiates apoptosis by stimulating Bax activity at the mitochondria 显示文摘 | Soucie EL Annis M Sedivy J | 2001 | Mol Cell Biol2001，21，： | 1 |
| 14 | Australia's response to HIV among peo-ple who inject drugs 显示文摘 | Annie M Alex W | 2014 | AIDS Educat Prevent2014，26，3： | 1 |
| 15 | Chemical and Biological Characterization of Patricles by flow cytometry in the Krka estuary, Croatia 显示文摘 | Patricia M T Matin J M Annie F | 1990 | Limnol Oceanogr1990，35，： | 1 |
| 16 | Biochemical and cellular effects of roscovitine,a potent and selective inhibitor of the cyclin- dependent kinesis,cdk2 and cdk5 显示文摘 | Laurent M Annie B Odile M | 1997 | Eur J Biochem1997，243，： | 1 |
| 17 | Hereditary variation in platelet integrin alpha 2 beta 1 density is associated with two silent polymorphisms in the alpha 2 gene coding sequence显示文摘 | Kunicki TJ Kritzik M Annis DS | 1997 | Blood1997，89，6： | 1 |
| 18 | Sperm cells of Zea mays have a complex complement of mRNAs显示文摘 | Engel M L Annie C Christian D | 2003 | Plant Journal2003，34，5： | 1 |
| 19 | Logic model: a tool for performance and management显示文摘 | Annie M Ronald SS John TC | 2001 | Evaluat Program Plann2001，，24： | 1 |
| 20 | Settlement prefer- ences and early migration of the tropical sea cucumber Holothuria scabra显示文摘 | Annie M Stephen C Jean--Francois H | 2000 | J Exp Mar Bio Ecol2000，249，： | 1 |
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