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| 1 | Giant squamous cell carcinoma of the gallbladder: A case report显示文摘BACKGROUND Gallbladder cancer is the most common malignant tumor of the biliary tract. The majority of cases are adenocarcinoma. Squamous cell carcinoma is the histological type present in 12% of all neoplasias accounting for approximately 12% of gallbladder neoplasms. It can occur in its pure form reaching 1%-3% of the tumors. Many patients are at an advanced stage when diagnosed and have bad therapeutic efficacy. CASE SUMMARY A 45-year-old male patient presented with left flank pain for 1 year and irradiated to the mesogastric region. He denied fever, vomiting, and any other intestinal changes. He reported a weight loss of 10 kg in a period of 7 mo. He denied alcoholism, smoking, drug use, or prior illness. Computed tomography of the abdomen showed in the gallbladder fossa a voluminous mesogastric heterogeneous collection that had a thick and irregular capsule with liquid and gaseous contents. A predominantly hypoattenuating rounded material with partially calcified margins measuring about 2.0 cm related to gallstone was also emphasized. No lymphadenomegalies or free fluid was observed in the abdominal cavity. Patient underwent laparotomy where a huge tumor was observed affecting the transverse colon and gallbladder. This mass was resected en bloc removing gallbladder and transverse colon together with corresponding mesocolon and regional lymphadenectomy. There were no complications in the postoperative period. Although oncological treatment was performed, the patient died 6 mo after surgery. CONCLUSION Squamous cell carcinoma represents a rare disease. Patients often present with large, bulky tumors with involvement of adjacent organs. In spite of progress in surgical techniques and adjuvant chemotherapy, the prognosis remains poor. | Marcelo AF Ribeiro Junior Murillo de Lima Favaro Stephanie Santin Cintia Magalhaes Silva Ana Paula Marconi Iamarino | 2019 | World Journal of Clinical Cases2019，7，18： | 2 |
| 2 | Recent insights intothe pathogenesis of bacterial sepsis显示文摘 | Anas AA Wiersinga WJ de Vos AF | 2010 | Neth J Med2010，68，4： | 1 |
| 3 | Role of CD14 in lung inflam?mation and infection显示文摘 | Anas A van der Poll T de Vos AF | 2010 | Crit Care2010，14，2： | 1 |
| 4 | Molluscicidal properties of some species of Annona显示文摘 | Santos AF San t'Ana AE | | 0，，： | 1 |
| 5 | Inheritance of capsaicin and dihydrocap:aicin, determined by HPLC-ESI/MS, in an in- traspecific cross of capsicum annuum L 显示文摘 | ANA GC RAM ANA AF | 2007 | J Agr Food Chem2007，55，17： | 1 |
| 6 | Protective effect of ions against cell death induced by acid stress in Saccharomyces显示文摘 | Sant'Ana GS Paes LS Paiva AF | | 0，，05： | 1 |
| 7 | Molluscicidal properties of some species of Annona 显示文摘 | Santos AF Sant' Ana AE | 2001 | Phytomedicine2001，8，2： | 1 |
| 8 | Recent insights into the pathogenesis of bacterial sepsis显示文摘 | Anas AA Wiersinga WJ de Vos AF | | 0，，： | 1 |
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