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| 1 | Carcinogenic Helicobacter pylori in gastric pre-cancer and cancer lesions: Association with tobacco-chewing显示文摘AIM:To investigate the low gastric cancer incidence rate relative to the highly prevalent Helicobacter pylori(H.pylori)infection;data relevant to H.pylori infection during gastric carcinogenesis in Indian patients is currently lacking.METHODS:The present study examines the prevalence of H.pylori infection in DNA derived from 156endoscopic gastric biopsies of different disease groups that represent gastric pre-cancer[intestinal metaplasia(n=15),dysplasia(n=15)],cancer[diffuse adenocarcinoma(n=44),intestinal adenocarcinoma(n=21)],and symptomatic but histopathologically-normal controls(n=61).This was done by generic ureC polymerase chain reaction(PCR)and cagA-specific PCR that could specifically identify the carcinogenic H.pylori strain.RESULTS:Our analysis showed the presence of H.pylori infection in 61%of symptomatic histopathologically-normal individuals,however only 34%of control tissues were harboring the cagA+H.pylori strain.A similar proportion of H.pylori infection(52%)and cagA(26%)positivity was observed in the tumor tissue of the gastric cancer group.In comparison,H.pylori infection(90%)and cagA positivity(73%)were the highest in gastric pre-cancer lesions.In relation to tobacco and alcohol abuse,H.pylori infection showed an association with tobacco chewing,whereas we did not observe any association between tobacco smoking or alcohol abuse with prevalence of H.pylori infection in the tissue of any of the patient groups studied.CONCLUSION:High incidence of H.pylori infection and carcinogenic cagA positive strain in pre-cancer lesions during gastric carcinogenesis may be | Arvind Pandey Satyendra Chandra Tripathi Sutapa Mahata Kanchan Vishnoi Shirish Shukla Sri Prakash Misra Vatsala Misra Suresh Hedau Ravi Mehrotra Manisha DwivediZ Alok C Bharti | 2014 | World Journal of Gastroenterology2014，20，22： | 4 |
| 2 | Information and effort in contingent valuation surveys: application to global climate change using national internet samples 显示文摘 | Berrens R P Alok K Bohara H C | 2004 | Journal of Environmental Economics and Management2004，47，： | 1 |
| 3 | Preparation of O,O- Diet-hylphosphorochloridothionate by Chlorination of O,O- Diethylphosphorodithioie Acid With Sulphur Monochloride显示文摘 | ALOK K B RAMESH C R NALEEN B | 1978 | Indian J Chem1978，16，： | 1 |
| 4 | Computerized Control of the VOD Process With the Application of a Mass Spectrometer 显示文摘 | Alok C Cerhard B Harald S | 1988 | Metallurgical Plant and Technology1988，，5： | 1 |
| 5 | Wear character- istics of plasma sprayed nickel-aluminum composite coatings 显示文摘 | Mishra S C Satapathy Alok Chhaithanya M | 2009 | Journal of Reinforced Plastics and Composites2009，28，23： | 1 |
| 6 | Anti-human popillomavirus therapeutics:Facts & future显示文摘 | Alok C Bharti S Sutapa M | 2009 | Indian J Med Res2009，130，： | 1 |
| 7 | Making sense of technology trends in the information tech- nology landscape: a design science approach 显示文摘 | GEDIMINASADOMAVICIUS JESSE C BOCKSTEDT ALOK GUP- TA | 2008 | MIS Quarterly2008，32，4： | 1 |
| 8 | Osmotic regulation of cell function and possible clinical applications显示文摘 | Alok S H Naoyuki H Yu C H | 2004 | Shock2004，21，： | 1 |
| 9 | Wedler Design and synthesis of new transition-state analog in- hibitors of aspartate transcarbamylase显示文摘 | G King Farrington Alok Kumar Frederick C | 1985 | J Med Chem1985，28，11： | 1 |
| 10 | Strength and durability characteristics of copper tailing concrete显示文摘 | Thomas B Alok D Gupta C R | 2013 | Construction and Building Materials2013，48，： | 1 |
| 11 | Imn-nickel bimetallic nanoparticles for reductive degradation of azo dye Orange G in aqueous solution显示文摘 | Alok D B Rajeev C C Chandrashekhar V R | 2008 | Applied Catalysis B: Environmental2008，79，3： | 1 |
| 12 | A high-performance application data environment for large-scale scientific computations显示文摘 | SHEN X H LIAO W K ALOK C | 2003 | IEEE Transactions on Parallel and Distributed Systems2003，14，12： | 1 |
| 13 | Nuclear factor-κB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients,and suppression of these transcription factors leads to apoptosis显示文摘 | Alok C Bharti Shishir Shishodia | 2004 | Blood2004，103，： | 1 |
| 14 | Iron- nickel bimetallic nanoparticles for reductive degradation of azo dye Orange G in aqueous soluion 显示文摘 | ALOK D RAJEEV C C CHANDRASHEKHAR V R | 2008 | Appl Catal B : Environ2008，79，： | 1 |
| 15 | Nuclear factor-kappa Band cancer:its role in prevention and therapy显示文摘 | Alok C Bharat B | 2002 | Biochem Phamacol2002，64，3： | 1 |
| 16 | Effect of atenolol on cadmium-induced testicular toxicity in male rats显示文摘 | BISWAS N M RANOJOY S G ALOK C | 2001 | Repro Toxicol2001，15，6： | 1 |
| 17 | 显示文摘 | Majumder M Aloke Kumar C Biswanath M | 2009 | New- York: Transport and Optical Properties of Nanomaterials- ICTOPON2009，，： | 1 |
| 18 | DNA Damage induced by industrial solid waste leachates in: Drosophila melanogaster a mechanistic approach 显示文摘 | Hifzur R S Anurag S Subash C G Ramesh C M Alok D Daya K S Dehapratim K C | 2008 | Environmental and Molecular Mutagenesis2008，49，： | 1 |
| 19 | A subset of quasars identified by large values of their doppler redshift 显示文摘 | Lu L Z Qin Y P Gupta Alok C | 2007 | The Astrophysical Journal2007，669，1： | 1 |
| 20 | Technology roles and paths of influence in an ecosystem model of technology evolution 显示文摘 | Gediminas Adomavicius Bockstedt J C Alok Gupta Kauffman R J | 2007 | Information Technology and Management2007，8，2： | 1 |
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