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1Crosstalk of liver immune cells and cell death mechanisms in different murine models of liver injury and its clinical relevance显示文摘BACKGROUND: Liver inflammation or hepatitis is a result of pluripotent interactions of cell death molecules, cytokines, chemokines and the resident immune cells collectively called as microenvironment. The interplay of these inflammatory mediators and switching of immune responses during hepatotoxic, viral, drug-induced and immune cell-mediated hepatitis decide the fate of liver pathology. The present review aimed to describe the mechanisms of liver injury, its relevance to human liver pathology and insights for the future therapeutic interventions.DATA SOURCES: The data of mouse hepatic models and relevant human liver diseases presented in this review are systematically collected from Pub Med, Science Direct and the Web of Science databases published in English. RESULTS: The hepatotoxic liver injury in mice induced by the metabolites of CCl4, acetaminophen or alcohol represent necrotic cell death with activation of cytochrome pathway, formation of reactive oxygen species(ROS) and mitochondrial damage. The Fas or TNF-α induced apoptotic liver injury was dependent on activation of caspases, release of cytochrome c and apoptosome formation. The Con A-hepatitis demonstrated the involvement of TRAIL-dependent necrotic/necroptotic cell death with activation of RIPK1/3. The α-Gal Cer-induced liver injury was mediated by TNF-α. The LPS-induced hepatitis involved TNF-α, Fas/Fas L, and perforin/granzyme cell death pathways. The MHV3 or Poly(I:C) induced liver injury was mediated by natural killer cells and TNF-α signaling. The necrotic ischemia-reperfusion liver injury was mediated byhypoxia, ROS, and pro-inflammatory cytokines; however, necroptotic cell death was found in partial hepatectomy. The crucial role of immune cells and cell death mediators in viral hepatitis(HBV, HCV), drug-induced liver injury, non-alcoholic fatty liver disease and alcoholic liver disease in human were discussed.CONCLUSIONS: The mouse animal models of hepatitis provide a parallel approach for the study of human liver pathology. Blocking or stimulating the pathways associated with liver cell death could unveil the novel therapeutic strategies in the management of liver diseases.Hilal Ahmad Khan Muhammad Zishan Ahmad Junaid Ali Khan Muhammad Imran Arshad 2017Hepatobiliary & Pancreatic Diseases International2017,16,3:24
2Correlation between KCNQ1 and KCNJ11 gene polymorphisms and type 2 and posttransplant diabetes mellitus in the Asian Indian population显示文摘Type 2 diabetes mellitus(T2DM)and post-transplant diabetes mellitus(PTDM)share a common pathophysiology.However,diabetes mellitus is a complex disease,and T2DM and PTDM have different etiologies.T2DM is a metabolic disorder,characterized by persistent hyperglycemia,whereas PTDM is a condition of abnormal glucose tolerance,with variable onset after organ transplant.The KCNQ1 and KCNJ11 gene encode potassium channels,which mediate insulin secretion from pancreatic b-cells,and KCN gene mutations are correlated with the development of diabetes.However,no studies have been carried out to establish an association between KCNQ1 and KCNJ11 gene polymorphisms and T2DM and PTDM.Therefore,our study was aimed at the identification of the role of KCNQ1 and KCNJ11 gene polymorphisms associated with T2DM and the risk of developing PTDM in the Asian Indian population.We have carried out a caseecontrol study including 250 patients with T2DM,250 control subjects,42 patients with PTDM and 98 subjects with non-PTDM.PCR-RFLP analysis was carried out following the isolation of genomic DNA from EDTA-blood samples.The results of the present study reveal that two single nucleotide polymorphisms(rs2283228 and rs5210,of the KCNQ1 and KCNJ11 genes,respectively)are associated with both T2DM and PTDM.The results of our study suggest a role of KCNQ1 and KCNJ11 gene variants in the increased risk of T2DM and PTDM in the Asian Indian population.Imran Ali Khan Kiran Kumar Vattam Parveen Jahan Kamal Kiran Mukkavali Qurratulain Hasan Pragna Rao 2015Genes & Diseases2015,2,3:6
3Electrocatalytic N_(2) reduction to NH3 with high Faradaic efficiency enabled by vanadium phosphide nanoparticle on V foil显示文摘To develop highly efficient electrochemical catalysts for N2 fixation is important to sustainable ambient NH_(3) production through the N_(2) reduction reaction(NRR).Herein,we demonstrate the development of vanadium phosphide nanoparticle on V foil as a high-efficiency and stable catalyst for ambient NH3 production with excellent selectivity.The high Faradaic efficiency of 22%with a large NH3 yield of 8.35×10^(−11) mol·s^(−1)·cm^(−2)was obtained at 0 V vs.the reversible hydrogen electrode in acid solution,superior to all previously studied V-based NRR catalysts.Density functional theory calculations are also utilized to have an insight into the catalytic mechanism.Peipei Wei Qin Geng Ali Imran Channa Xin Tong Yongsong Luo Siyu Lu Guang Chen Shuyan Gao Zhiming Wang Xuping Sun 2020Nano Research2020,13,11:4
4β-Ga_2O_3 thin film grown on sapphire substrate by plasmaassisted molecular beam epitaxy显示文摘Monoclinic gallium oxide(Ga_2O_3) has been grown on(0001) sapphire(Al_2O_3) substrate by plasma-assisted molecular beam epitaxy(PA-MBE). The epitaxial relationship has been confirmed to be [010]( 2ˉ01) β-Ga_2O_3||[ 011ˉ0](0001)Al_2O_3 via in-situ reflection high energy electron diffraction(RHEED) monitoring and ex-situ X-ray diffraction(XRD) measurement. Crystalline quality is improved and surface becomes flatter with increasing growth temperature, with a best full width at half maximum(FWHM) of XRD ω-rocking curve of( 2ˉ01) plane and root mean square(RMS) roughness of 0.68° and 2.04 nm for the sample grown at 730 °C,respectively. Room temperature cathodoluminescence measurement shows an emission at ~417 nm, which is most likely originated from recombination of donor–acceptor pair(DAP).Jiaqi Wei Kumsong Kim Fang Liu Ping Wang Xiantong Zheng Zhaoying Chen Ding Wang Ali Imran Xin Rong Xuelin Yang Fujun Xu Jing Yang Bo Shen Xinqiang Wang 2019Journal of Semiconductors2019,40,1:4
5Synergistic antibacterial effect of honey and Herba Ocimi Basilici against some bacterial pathogens显示文摘OBJECTIVE: To evaluate the antibacterial activity of the combination of different honey brands and methanolic fraction of Herba Ocimi Basilici using agar well diffusion assay. METHODS: The antibacterial activity was determined against thirteen pathogenic bacterial clinical isolates including six gram negative(Klebsiella pneumonia, Pseudomonas aeroginosa, Escherichia coli, Salmonella typhi, Salmonella typhimirium, Xanthomonas campestris) and six gram positive strains(Enterococcus faecalis faecalis, Bacillus subtilis, Staphylococcus aureus, Clostridium perfringens type C, Clostridium perfringens type D, Clostridium chauvoei). Agar well diffusion method was used while zones of inhibition were measured with vernier scale. RESULTS: At higher concentration, all the honey brands showed good to significant activity. The highest activity was observed for Hamdard brand honey(27.60±0.40) against Enterococcus faecalis. CONCLUSION: These results revealed that combinations of plant extracts of Herba Ocimi Basilici with honey can be used for the development of potent and novel antibacterial agents.Ali Talha Khalil Imran Khan Kafeel Ahmad Yusra Ali Khan Momin Khan Muhammad Jaseem Khan 2013Journal of Traditional Chinese Medicine2013,33,6:4
6Seedling-lump integrated non-destructive monitoring for automatic transplanting with Intel RealSense depth camera显示文摘Non-destructive plant growth parameters measurement is an important concern in automatic-seedling transplanting.Recently,several image-basedmonitoring approaches have been proposed and potentially developed for several agricultural applications.The presented study proposed and developed a RealSense-based machine vision system for the close-shot seedling-lump integrated monitoring.The strategy was based on the close-shot depth information.Further,the point cloud clustering and suitable algorithms were applied to obtain the segmentation of 3D seedling models.In addition,the data processing pipeline was developed to assess the differentmorphological parameter of 4 different seedling varieties.The experiments were carried out with 4 different seedling varieties(pepper,tomato,cucumber,and lettuce)and trained under different light conditions(light and dark).Moreover,analysis results showed that therewas not significantly different(p<0.05)found towards light and dark environments due to close-shot near-infrared detection.However,the results revealed that the stem diameter relationship between RealSense and the manual method was found for R^2=0.68 cucumber,R^2=0.54 tomato,R^2=0.35 pepper,and R^2=0.58 lettuce seedlings.Whereas,the seedling height relationship between RealSense and the manual methodwas found higher than R^2=0.99,0.99,0.99,and 0.99 for pepper,tomato,cucumber,and lettuce,respectively.Based on the experiment results,it was concluded that the RGB-D integrated monitoring system with the purposed method could be practiced for nursery seedlings most promisingly without high labour requirements in terms of ease of use.The system revealed a good sturdiness and relevance for plant growth monitoring.Additionally,it has the perspective for future practical value to real-time vision servo operations for transplanting robots.Tabinda Naz Syed Liu Jizhan Zhou Xin Zhao Shengyi Yuan Yan Sami Hassan Ahmed Mohamed Imran Ali Lakhiar 2019Artificial Intelligence in Agriculture2019,,3:4
7Discovering interlinkages between major cryptocurrencies using high‑frequency data: new evidence from COVID‑19 pandemic显示文摘Through the application of the VAR-AGARCH model to intra-day data for three cryptocurrencies(Bitcoin,Ethereum,and Litecoin),this study examines the return and volatility spillover between these cryptocurrencies during the pre-COVID-19 period and the COVID-19 period.We also estimate the optimal weights,hedge ratios,and hedging effectiveness during both sample periods.We find that the return spillovers vary across the two periods for the Bitcoin–Ethereum,Bitcoin–Litecoin,and Ethereum–Litecoin pairs.However,the volatility transmissions are found to be different during the two sample periods for the Bitcoin–Ethereum and Bitcoin–Litecoin pairs.The constant conditional correlations between all pairs of cryptocurrencies are observed to be higher during the COVID-19 period compared to the pre-COVID-19 period.Based on optimal weights,investors are advised to decrease their investments(a)in Bitcoin for the portfolios of Bitcoin/Ethereum and Bitcoin/Litecoin and(b)in Ethereum for the portfolios of Ethereum/Litecoin during the COVID-19 period.All hedge ratios are found to be higher during the COVID-19 period,implying a higher hedging cost compared to the pre-COVID-19 period.Last,the hedging effectiveness is higher during the COVID-19 period compared to the pre-COVID-19 period.Overall,these findings provide useful information to portfolio managers and policymakers regarding portfolio diversification,hedging,forecasting,and risk management.Imran Yousaf Shoaib Ali 2020Financial Innovation2020,6,1:4
8Mechanical strength of wheat grain varieties influenced by moisture content and loading rate显示文摘Mechanical shear resistance of wheat grain is a significant concern for the designers and researchers related to the design of threshing,handling and processing machinery of the field crops.The grain mechanical properties directly affect the machine geometry and its operational parameters.The present study was carried out to determine the shear resistance of five wheat varieties(Locally names;TD-02,Sindhu-1105,Benazir,China and SKD-118)influenced by moisture content(16.7%,18.7%and 19.5%)and loading rate(3 mm/s,6 mm/s and 9 mm/s).However,some physio-dimensional properties(length,width,thickness,slenderness ratio,surface area and sphericity)were obtained at different moisture contents.The results showed that the shear resistance reduced by increasing the moisture content and loading rate.The average shear resistance decreased from 10.45 N to 3.74 N for 3-9 mm/s loading rate at moisture content of 16.7%to 19.5%.Thus,the maximum correlation(r=0.905)of shear resistance obtained at 16.7%,whereas minimum correlation(r=0.692)obtained at 19.5%.The shear resistance of wheat grain was highly significant(p<0.05)at 9 mm/s for 19.5%.Shear resistance decreased with an increase in the moisture content in the grain whereas deformation is increasing with the increase of moisture content.However,the maximum bulk density of wheat grain obtained at 19.5%for SKD-118,while the minimum obtained at 16.7%for TD-02.It is recommended that the design and modification of wheat grain processing equipment should be executed on the physio-mechanical properties of grain varieties.Yaoming Li Farman Ali Chandio Zheng Ma Imran Ali Lakhiar Abdul Razaque Sahito Fiaz Ahmad Irshad Ali Mari Umer Farooq Muhammad Suleman 2018International Journal of Agricultural and Biological Engineering2018,11,4:4
9Slippery Photothermal Trap for Outstanding Deicing Surfaces显示文摘Ice accumulation is a safety and operational threat in power lines,wind turbines,and transportations.Surfaces having both passive anti-icing and active deicing functionalities are very rare.Here,we report a self-cleaning slippery photothermal trap,which is icephobic passively and deice the surfaces actively by converting sun light to heat at the ice-substrate interface.The photothermal trap consists of three layers:a candle soot layer act as solar radiation absorber,a magnetic iron oxide Fe_(3)O_(4) nanoparticles layer act as heat spreader for lateral dispersal of sun light,and Room Temperature Vulcanized(RTV)insulation to reduce the transverse heat loss.Upon illumination under microsolar 300,the temperature of the surface increased by 40℃ within 200 s.The heat confinement at the magnetic Fe_(3)O_(4) na-noparticles layer leads to rapid increase of the surface temperature,ice start to melt and silicone lubricant facilitates the ice removal.The slippery photothermal trap removed the frozen droplet(10 fiL)within 40 s upon the illumination of sun light and the frozen droplet was completely converted into water after 7 min illumination of solar light at-20℃.The developed slippery photothermal trap also melted the fully frost covered layer within 100 s at-20℃ under sunlamp.The average defrosted length(25 mm)was also observed by irradiation of laser light for 45 s.The self-cleaning slippery photothermal coating showed outstanding deicing performance at subzero temperature for long term due to the infusion of silicone oil into the nanostructures and same chemical composition with binder.Muhammad Imran Jamil Qiongyan Wang Amjad Ali Munir Hussain Tariq Aziz Xiaoli Zhan Qinghua Zhang 2021Journal of Bionic Engineering2021,18,3:3
10Technical efficiency of hybrid maize growers: A stochastic frontier model approach显示文摘This study investigated the effect of credit constraints and credit unconstraints on the technical efficiency of hybrid maize growers in the Khyber Pakhtunkhwa Province(KPK) of Pakistan. The primary data were collected by a direct elicitation method from 510 maize growers of KPK Province. Stochastic frontier model techniques were used for technical efficiency analyses. The results revealed that the mean technical efficiency difference between the two groups was 10.2%. The results of technical inefficiency effect modeling demonstrated that education of the household head, family size, number of married family members, off-farm income, farming experience, tractor drill, water irrigation through a lined course, certified seed, extension services, household saving variables, and a credit size variable had positive effects on technical efficiency for both credit constrained farmers(CCFs) and credit unconstrained farmers(UCCFs). In addition, age of household head and fragmented land values had negative effects on technical efficiency for both groups. However, the interest rate had positive and negative impacts on the technical efficiency of CCFs and UCCFs, respectively. Our results have significant implications for policies related to land use, interest rate, and banking sector expansion in the rural areas of Pakistan.Imad Ali HUO Xue-xi Imran Khan Hashmat Ali Khan Baz Sufyan Ullah Khan 2019Journal of Integrative Agriculture2019,18,10:3
11Livestock production and population census in Pakistan:Determining their relationship with agricultural GDP using econometric analysis显示文摘Livestock is a subsector of Pakistan agriculture which contributes approximately 56%of value addition in agriculture and nearly 11%to the gross domestic product(GDP).Livestock production makes a major contribution to agriculture value added services.In order to highlight the actual performance of livestock production and livestock and poultry products,the study explored the relationship between agricultural GDP and livestock product output,including milk,beef,mutton,poultry meat,eggs,wool,hair,skins,hides and bones,in Pakistan over the 35 year period from 1980 to 2015.Time series data were collected from the National Food Security and Research,the Economic Survey of Pakistan and the Pakistan Bureau of Statistics(various publications).Livestock data were analysed using the ordinary least squares(OLS)method and the Augmented Dickey-Fuller(ADF)test,and the results were interpreted using the Johansen co-integration test.Our study found that the output of milk,fat,eggs,bones and mutton has a positive,significant relationship to the agricultural GDP of Pakistan,while the output of beef,poultry meat,wool,hair,skins and hides has a negative,insignificant relationship to the agricultural GDP of Pakistan.Therefore,the study suggests that the government of Pakistan initiates new funding schemes for the development of the livestock sector.Abdul Rehman Luan Jingdong Abbas Ali Chandio Imran Hussain 2017Information Processing in Agriculture2017,4,2:3
12茉莉酸对油菜(Brassica napus L.)受镉毒害的缓解作用(英文)显示文摘目的:本研究目的在于了解:(1)喷施外源茉莉酸对受到镉胁迫油菜的作用;(2)是否茉莉酸能够通过增强气体交换,从而保护受到氧化胁迫的地上部分组织的叶绿体,进而通过减少镉的吸收来维持离子平衡;(3)是否通过喷施茉莉酸来对具有减缓镉毒害效应的抗氧化酶的活性进行调节。创新点:茉莉酸能够调节响应胁迫的抗氧化酶的活性,从而通过保护叶绿体免受活性氧(ROS)伤害而提高光合产物的能力,最大限度地缓解油菜植株受到的镉毒害。方法:(1)叶片气体交换;(2)叶片光合色素分析;(3)丙二醛与抗氧化酶活性分析;(4)营养成分分析;(5)透射电镜亚细胞水平观察。结论:茉莉酸对于植物受镉毒害的缓解作用的机理在于减少叶片中镉的积累,从而减轻氧化胁迫过程中产生的ROS对于膜系统的损害程度。Essa ALI Nazim HUSSAIN Imran Haider SHAMSI Zahra JABEEN Muzammil Hussain SIDDIQUI Li-xi JIANG 2018Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2018,19,2:2
13Experimental study of ultrasonic atomizer effects on values of EC and pH of nutrient solution显示文摘The objectives of this research were to reveal how main working parameters of ultrasonic atomizers would influence key properties of the atomized nutrient solution in an aeroponics system.The Yamazaki tomato nutrient solution was selected as a nutrient example.Uniform design(UD)method U_(12)(12^(2)×13)was adopted to arrange the test.In this test,spraying time and interval time were taken as quantitative factors with 12 levels(10,20,30,40,50,60,70,80,90,100,110,and 120 min,respectively),and ultrasonic atomizer frequency was taken as qualitative factor with 3 conditions(28 kHz,107 kHz,1.7 MHz).Based on test data,two regression formulations used to predict the values ofΔEC,andΔpH of atomized Yamazaki tomato nutrient solution was established and inspected.The spraying interval time of ultrasonic atomizers had no significant effect on EC and pH of the atomized Yamazaki tomato nutrient solution;the ultrasonic atomizer frequency was more effective than spraying time on the values of EC and pH;the values of EC and pH became maximum at(f_(3),T_(1))=(1.7 MHz,120 min)and minimum at(f_(1),T_(1))=(28 kHz,10 min).It was concluded that the effect of high-frequency(1.7 MHz)ultrasonic atomizer on EC and pH of the Yamazaki tomato nutrient solution was beyond the standard value for tomato growth.Therefore,the high-frequency(1.7 MHz)ultrasonic atomizer is not suitable for aeroponics cultivation when using the Yamazaki tomato nutrient solution as aeroponics nutrient solution.Imran Ali Lakhiar Xingda Liu Guanqun Wang Jianmin Gao 2018International Journal of Agricultural and Biological Engineering2018,11,5:2
14Effect of family control on corporate dividend policy of firms in Pakistan显示文摘This study examines the impact of family control on the dividend policy of firms in Pakistan,covering the period from 2009 to 2016.It also investigates whether family control moderates the impact of firm-specific factors on the dividend policy.The GMM model for panel data estimation is used.The mean difference univariate analysis shows that family firms differ from nonfamily firms based on financial characteristics.The multivariate analysis shows that family firms pay lower dividends than nonfamily firms.Besides,firm size inversely affects the dividend policy,whereas tangibility positively affects it.Moreover,family control does not moderate the impact of all firm-specific factors on the dividend policy.Overall,family control,size,and tangibility are found to be the main determinants of the dividend policy in Pakistan.Imran Yousaf Shoaib Ali Arshad Hassan 2019Financial Innovation2019,5,1:2
15Herding behavior in Ramadan and financial crises: the case of the Pakistani stock market显示文摘This study examines herding behavior in the Pakistani Stock Market under different market conditions,focusing on the Ramadan effect and Crisis period by using data from 2004 to 2014.Two regression models of Christie and Huang(Financ Analysts J 51:31-37,1995)and Chang et al.,(J Bank Finance 24:1651-1679,2000)are used for herding estimations.Results based on daily stock data reveal that there is an absence of herding behavior during rising(up)and falling(down)market as well as during high and low volatility in market.While herding behavior is detected during low trading volume days.Yearly analysis shows that herding existed during 2005,2006 and 2007,while it is not evident during rest of the period.However,herding behavior is not detected during Ramadan.Furthermore,during financial crisis of 2007-08,Pakistani Stock Market exhibits herding behavior due to higher uncertainty and information asymmetry.Imran Yousaf Shoaib Ali Syed Zulfiqar Ali Shah 2018Financial Innovation2018,4,1:2
16Effects of different irrigation frequencies and incorporation of rice straw on yield and water productivity of wheat crop显示文摘The current rapid increase in irrigation water consumption is considered unsustainable and threatens the world food production.Therefore,it is mandatory to promote modern techniques and to manage existing conventional irrigation methods.The present study was attempted to determine the effects of different irrigation frequencies and rice straw incorporation rates on yield and water productivity of the wheat crop.The experiment was arranged with randomize complete block design involving nine treatments(RS 0 I 7,RS 0 I 15,RS 0 I 22,RS 1 I 7,RS 1 I 15,RS 1 I 22,RS 2 I 7,RS 2 I 15 and RS 2 I 22)under three replications.Results exposed that the incorporation of rice straw with different irrigation frequencies significantly improved physico-chemical properties of soil.Moreover,soil bulk density,infiltration rate,pH,electrical conductivity significantly decreased and soil porosity significantly increased under all treatments.Furthermore,maximum crop yield and crop water productivity of 7706.4 kg/hm 2 and 1.92 kg/m 3 respectively were found under RS 1 I 15 treatment.Based on experimental results it can be concluded that irrigation frequency and incorporation of rice straw had significant effects on the physico-chemical properties of soil,total grain yield and water productivity of the wheat crop.However,this study suggested that the wheat crop yield and water productivity could be increased by incorporating 1 t/hm 2 rice straw with 15 d of irrigation frequency.Mazhar Hussain Tunio Jianmin Gao Mashooque Ali Talpur Imran Ali Lakhiar Farman Ali Chandio Sher Ali Shaikh Kashif Ali Solangi 2020International Journal of Agricultural and Biological Engineering2020,13,1:2
17Text Sentiment Analysis Using Frequency-Based Vigorous Features显示文摘Sentiment Analysis, an un-abating research area in text mining, requires a computational method for extracting useful information from text. In recent days, social media has become a really rich source to get information about the behavioral state of people(opinion) through reviews and comments. Numerous techniques have been aimed to analyze the sentiment of the text, however, they were unable to come up to the complexity of the sentiments. The complexity requires novel approach for deep analysis of sentiments for more accurate prediction. This research presents a three-step Sentiment Analysis and Prediction(SAP) solution of Text Trend through K-Nearest Neighbor(KNN). At first, sentences are transformed into tokens and stop words are removed. Secondly, polarity of the sentence, paragraph and text is calculated through contributing weighted words, intensity clauses and sentiment shifters. The resulting features extracted in this step played significant role to improve the results. Finally, the trend of the input text has been predicted using KNN classifier based on extracted features. The training and testing of the model has been performed on publically available datasets of twitter and movie reviews. Experiments results illustrated the satisfactory improvement as compared to existing solutions. In addition, GUI(Hello World) based text analysis framework has been designed to perform the text analytics.Abdul Razzaq Muhammad Asim Zulqrnain Ali Salman Qadri Imran Mumtaz Dost Muhammad Khan Qasim Niaz 2019China Communications2019,16,12:2
18Anxiolytic potential of ursolic acid derivative-a stearoyl glucoside isolated from Lantana camara L.(verbanaceae)显示文摘Objective:To investigate the anxiolytic activity of newly isolated compound by our lab called ursolic acid stearoyl glucoside(UASG) from the leaves of Lantana camam(L camam).Methods: Column chromatography was used to isolate UASG.Anxiolytic potential was experimentally proved and demonstrated through Elevated plus-maze,Open field and light and dark test. Results:The UASG showed marked increased in time spent(%) and number of frequent movements made by animals in open arm of elevated plus-maze apparatus.In light and dark model,UASG produced marked increase in time spent by animal,number of crossing and reduced duration of immobility in light box.Conclusions:UASG showed significant increase in number of rearing,assisted rearing and number of square crossed in open field established test model.UASG showed its anxiolytic effect in dose dependent manner.Imran Kazmi Muhammad Afzal Babar Ali Zoheir A.Damanhouri Aftab Ahmaol Firoz Anwar 2013Asian Pacific Journal of Tropical Medicine2013,6,6:2
19Effective age of information in real-time wireless feedback control systems显示文摘Ultra-reliable and low-latency communication(URLLC)is one of the most important scenarios in forthcoming fifth generation(5 G)cellular networks to ensure timely exchange of information and realize real-time wireless control.In URLLC,timely information update needs to be guaranteed since control performance,e.g.,control cost and stability,is directly determined by timely control information update.In this paper,we introduce an effective age of information(EAoI)to evaluate the timeliness of information update in control process.We consider the control process with two phases:sensor to controller phase and controller to actuator phase.We adopt first-generate-first-serve(FGFS)M/M/1/1→M/M/1/2 and FGFS M/M/1/1~*→M/M/1/2~*tandem queuing models to represent control process and we use finitestate Markov chains to describe control information updates.By studying state transitions,we calculate the average EAoI for both tandem queuing models.More importantly,we analyze throughput of wireless control systems and its relationship with average EAoI,which provides a guideline for URLLC system design in real-time feedback control systems.Simulation results show the advantage of using EAoI.Bo CHANG Burak KIZILKAYA Liying LI Guodong ZHAO Zhi CHEN Muhammad Ali IMRAN 2021Science China(Information Sciences)2021,64,2:2
20Removal of lead and cadmium ions by single and binary systems using phytogenic magnetic nanoparticles functionalized by 3-marcaptopropanic acid显示文摘The present research study is focused on green fabrication of superparamagnetic Phytogenic Magnetic Nanoparticles(PMNPs), and then its surface functionalization with 3-Mercaptopropionic acid(3-MPA). The resulting material(i.e. 3-MPA@PMNPs) characterized by FTIR, powder XRD, SEM, TEM, EDX, VSM, BET and TGA techniques and then further employed for the investigation of the adsorptive removal of lead(Pb^2+) and cadmium(Cd^2+) ions from aqueous solutions in single and binary systems. The material showed fastest adsorptive rate(98.23%) for Pb^2+ and(96.5%) Cd2+within the contact time of 60 min at pH 6.5 in the single system. The experimental data were fitted well to Langmuir isotherm, indicated monolayer adsorption of both metal ions onto 3-MPA@PMNPs and an estimated comparable adsorptive capacity of 68.41 mg·g^-1(Pb2+) and 79.8 mg·g^-1(Cd2+) at p H 6.5. However, kinetic data agreed well with pseudo-second-order model, and indicated that the removal mainly supported chemisorption and/or ion-exchange mechanism. Thermodynamic parameters such asΔGo,ΔHo, and ΔSo, were-3259.20, 119.35 and 20.73 for Pb^2+, and-1491.10, 45.441 and 7.87 for Cd^2+ at temperature 298.15 K, confirmed that adsorption was endothermic, spontaneous and favorable. The material demonstrated higher selectivity of Pb2+ and its removal efficiency was(98.20 ± 0.3)% in binary system experiments. The material persisted performance up-to seven(07) consecutive treatment cycles without losing their stability and offered comparable fastest magnetic separation(35 s) from aqueous solutions. Therefore, it is recommended that the prepared material can be employed to remove toxic heavy metal ions from water/wastewaters and this 'green' method can easily be implemented at large scale in low economy countries.Imran Ali Changsheng Peng Iffat Naz 2019Chinese Journal of Chemical Engineering2019,27,4:2
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