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| 1 | Osteosarcopenia in autoimmune cholestatic liver diseases:Causes,management,and challenges显示文摘Primary biliary cholangitis and primary sclerosing cholangitis(PSC)are the most common cholestatic liver diseases(CLD)in adults and are both characterized by an immune pathogenesis.While primary biliary cholangitis is a model autoimmune disease,with over 90%of patients presenting very specific autoantibodies against mitochondrial antigens,PSC is considered an immune mediated disease.Osteoporosis is the most common bone disease in CLD,resulting in frequent fractures and leading to significant morbidity.Further,sarcopenia is emerging as a frequent complication of chronic liver diseases with a significant prognostic impact and severe implications on the quality of life of patients.The mechanisms underlying osteoporosis and sarcopenia in CLD are still largely unknown and the association between these clinical conditions remains to be dissected.Although timely diagnosis,prevention,and management of osteosarcopenia are crucial to limit the consequences,there are no specific guidelines for management of osteoporosis and sarcopenia in patients with CLD.International guidelines recommend screening for bone disease at the time of diagnosis of CLD.However,the optimal monitoring strategies and treatments have not been defined yet and vary among centers.We herein aim to comprehensively outline the pathogenic mechanisms and clinical implications of osteosarcopenia in CLD,and to summarize expert recommendations for appropriate diagnostic and therapeutic approaches. | Nicola Pugliese Ivan Arcari Alessio Aghemo Andrea G Lania Ana Lleo Gherardo Mazziotti | 2022 | World Journal of Gastroenterology2022，28，14： | 2 |
| 2 | Oxygen radical absorbance capacity assay for antioxidants 显示文摘 | Cao G Alessio HM Cutler RG | 1993 | Fre Rad Boil Med1993，14，3： | 1 |
| 3 | Geographical variation in water relations,hydraulic architecture and terpene composition of Aleppo pine seedlings from Italian provenances显示文摘 | Tognetti R Michelozzi M Alessio G | 1997 | Tree Physiology1997，17，： | 1 |
| 4 | Primary and secondary prevention of atherosclerosis:is there a role for antiox-idants显示文摘 | Paolisso G Esposito R D′Alessio MA Barbieri M | | 0，，04： | 1 |
| 5 | From Plants to Birds:Higher Avian Predation Rates in Trees Responding to Insect Herbivory 显示文摘 | MANTYLA E ALESSIO G A BLANDE J D | 2008 | PLoS 0NE2008，3，7： | 1 |
| 6 | Patterns and technologies for enabling supply chain traceability through collaborative e-business显示文摘 | Alessio Bechini Mario G C A Cimino | 2008 | Information and Software Technology2008，，34： | 1 |
| 7 | Oxygen radical absorbane capacity assay for antioxidants显示文摘 | Cao G Alessio HM Culter RG | 1993 | Fre Rad Bio Med1993，14，： | 1 |
| 8 | Neonatal blood tests to exclude caesarean section as a cause of mater- hal-fetal transmission of hepatitis C 显示文摘 | Giorlandino C Gambuzza G D'Alessio P | 1995 | Lancet1995，346，8979： | 1 |
| 9 | Waler sources and water-use efficiency in Mediterranean coastal dune vegeta- tion显示文摘 | Alessio G A De Lillis M Brugnoli E | 2004 | Plant Biology2004，，6： | 1 |
| 10 | Oxygen - radical absorbance capacity assay tor antioxidants 显示文摘 | Cao G Alessio HM Cutler RG | 1993 | Free Radic Biol Med1993，14，3： | 1 |
| 11 | Oxygen-radi- cal absorbance capacity assay for antioxidants显示文摘 | CAO G ALESSIO H M CUTLER R G | 1993 | Free Radic Biol Med1993，14，3： | 1 |
| 12 | From plants tobirds:Higher avian predation rates in trees responding to in-sect herbivory显示文摘 | M ntyl E Alessio G A Blande J D | 2008 | PLoS One2008，3，7： | 1 |
| 13 | The bactericidal action on Escherichia coli of ZF-RNase-3 is triggered by the suicidal action of the bacterium OmpT protease 显示文摘 | Zanfardino A Pizzo E Di Maro A Varcamonti M D'Alessio G | 2010 | FEBS J2010，277，8： | 1 |
| 14 | Role of the microenvironment in the specification of endothelial progenitors derived from embryonic stem cells显示文摘 | Alessio N Federico B Anna G | 2010 | Microvascular Research2010，79，3： | 1 |
| 15 | Blood contamination of amniotic fluid after amniocentesis in relation to placental location显示文摘 | Giorlandino C Gambuzza G D'Alessio P | 1996 | Prenat Diagn1996，16，2： | 1 |
| 16 | Localization of spherical fruits for robotic harvesting显示文摘 | Alessio P Giorgio G | 2001 | Machine Vision and Application2001，13，2： | 1 |
| 17 | Single--Layer versus multilayer preplanned lightpath restoration显示文摘 | ALESSIO G VALCARENGHI L CASTOLDI P | 2005 | Journal of lightwave technology2005，23，10： | 1 |
| 18 | Zirconium carbide thin films deposited by pulsed laser ablation显示文摘 | ALESSIO L D SANTAGATA A TEGHIL R ZACCAGNINO M ZACCARDO I MAROTTA V FERRO D MARIA G D | 2000 | Appl Surf Sci2000，168，14： | 1 |
| 19 | Abatacept for severe anti-tumor necrosis factor refractory ju- venile idiopathic arthritis-related uveitis显示文摘 | Zulian F Balzarin M Falcini F Martini G Alessio M Cimaz R | 2010 | Arthritis Care Res [Hoboken]2010，62，6： | 1 |
| 20 | Chemoradiation with or without intraoperative radiation therapy in patients with locally recurrent rectal carcinoma: prognostic factor and long term outcome 显示文摘 | Vincenzo Valentini Alessio G Morganti Antonio De Franco | 1999 | Cancer1999，86，： | 1 |
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