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57篇 您的检索式:作者名="ADOLFSSON J"
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1Anti-inflammatory effects of bifidobacteria by inhibition of LPS-induced NF-κB activation显示文摘AIM: Different strains of bifidobacteria were analysed for their effects on HT-29 intestinal epithelial cells (IECs) in in vitro models both of the non-inflamed and inflamed intestinal epithelium. METHODS: A reporter gene system in HT-29 cells was used to measure levels of NF-KB activation after challenge with bifidobacteria or after bacterial pre-treatment following LPS challenge. IL-8 protein and pro-inflammatory gene expression was investigated using normal HT-29 cells. RESULTS: None of the bifidobacteria tested induced activation of nuclear factor KB (NF-KB) indicating that bifidobacteria themselves do not induce inflammatory events in IECs. However, six out of eight bifidobacteria tested inhibited lipopolysaccharide- (LPS-) induced NFKB activation in a dose- and strain-dependent manner. In contrast, NF-KB activation in response to challenge with tumor necrosis factor-α(TNF-α) was affected by none of the tested bifidobacteria, indicating that the inhibitory effect of bifidobacteria is specific for LPS-induced inflammation in IECs. As shown with two of the six inhibitionpositive bifidobacteria, LPS-induced inhibition of NFKB activation was accompanied by a dose-dependent decrease of interleukin 8 (IL-8) secretion and by lower mRNA levels for IL-8, TNF-a, cyclooxygenase 2 (Cox-2), and intercellular adhesion molecule 1 (ICAM-1). CONCLUSION: Some strains of bifidobacteria are effective in inhibiting LPS-induced inflammation and thus might be appropriate candidates for probiotic intervention in chronic intestinal inflammation.Christian U Riedel Francis Foata David Philippe Oskar Adolfsson Bernhard J Eikmanns Stephanie Blum 2006World Journal of Gastroenterology2006,12,23:14
2Identifying childfunctioning from an ICF-CY perspective: Everyday life sit-uations explored in measures of participation 显示文摘Adolfsson M Malmqvist J Pless M 2011DisabilRehabil2011,33,1314:1
3The HCL-32: towards a self-assessment tool for hypomanic symptoms in outpatients显示文摘Angst J Adolfsson R Benazzi F 2005JAffect Disord2005,88,:1
4Identifying childfunctioning from an ICF-CY perspective: Everyday life sit-uations explored in measures of participation 显示文摘Adolfsson M Malmqvist J Pless M 2011DisabilRehabil2011,33,1314:1
5Bone response to free form- fabricated hydroxyapatite and zirconia scaffolds: a histological study in the human maxilla显示文摘Malmstrom J Slotte C Adolfsson E 2009Clin Oral Implants Res2009,,20:1
6Endogenously formed nitric oxide modulates cell growth in bladder cancer cell lines 显示文摘Morcos E Jansson OT Adolfsson J 1999Urology1999,53,:1
7Key Role of flt3 Ligand in Regulation of the Common Lymphoid Progenitor but Not in Maintenance of the Hematopoietic Stem Cell Pool显示文摘Ewa Sitnicka David Bryder Kim Theilgaard-M?nch Natalija Buza-Vidas J?rgen Adolfsson Sten Eirik W Jacobsen 2002Immunity2002,,4:1
8Upregulation of Flt3 Expression within the Bone Marrow Lin ? Sca1 + c-kit + Stem Cell Compartment Is Accompanied by Loss of Self-Renewal Capacity显示文摘J?rgen Adolfsson Ole Johan Borge David Bryder Kim Theilgaard-M?nch Ingbritt ?strand-Grundstr?m Ewa Sitnicka Yutaka Sasaki Sten E.W Jacobsen 2001Immunity2001,,4:1
9Nitril oxide synthase activity in the human urogenital tract 显示文摘Ehren I Adolfsson J Wiklund NP 1994Urol Res1994,22,5:1
10Bone ingrowth in zirconia and hydroxyapatite scaffolds with identical macroporos- ity显示文摘Malmstrom J Adolfsson E Emanuelsson L 2008J Mater Sci Mater Med2008,19,9:1
11Cutting force model for multi-toothed cutting processes and force measuring equipment for face milling显示文摘ADOLFSSON C STAHL J 1995International Journal of Machine Tools and Manufacture1995,35,12:1
12The HCL-32 : Towards a self-assessment tool for hypomanic symptoms in outpatients 显示文摘Angst J Adolfsson R Bennazzi F 2005J Affect Disord2005,88,:1
13Identification of Lin(-)Sca1(+)c-kit(+)CD34(+)Flt3(-) short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients显示文摘Yang L Bryder D Adolfsson J 2005Blood2005,105,:1
14Identification of Lin(-) Scal(+) kit(+)CD34(+) Flt3- short-term hematopoietie stem cells capable of rapidly reconstituting and rescuing myeloahlated transplant recipients显示文摘Yang L Bryder D Adolfsson J 2005Blood2005,105,7:1
15Patterns of triangular fibrocartilage complex (TFCC) injury associated with severely dorsally displaced extrarticular distal radius fractures显示文摘Scheer J H Adolfsson L E 2012Injury2012,43,6:1
16The management of category T1 a - T1 b (Incidental) prostate cancer: can we predict who needs treatment 显示文摘Adolfsson J 2008Eur Urol2008,54,1:1
17Design and simulation of component-based manufacturing machine sys- tems显示文摘ADOLFSSON J NG A OLOFSGARD P 2002Mechatronics2002,,12:1
18Upregulation of Flt3 expression within the bone marrow Lin ( - ) Scal ( + ) c-kit ( + ) stem cell compartment is accompanied by loss of self-renewal capacity 显示文摘Adolfsson J Borge O J Bryder D 2001Immunity2001,15,4:1
19hnpact of comor bidity on management and mortality in women diagnosed with breast cancer 显示文摘Berglund A Wigertz A Adolfsson J 2012Breast Cancer Res Treat2012,135,1:1
20Continuous glucose monitoring-- a study of the Enlite sensor during hypo - and hyperbaric conditions 显示文摘Adolfsson P Ornhagen H Jendle J 2012Diabetes Technol Ther2012,14,6:1
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