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| 1 | Intraductal papillary neoplasm of the bile ducts: A case report and literature review显示文摘Intraductal papillary neoplasm of the bile duct(IPNB) is a rare bile duct neoplasm mostly found in far eastern nations where hepatolithiasis and clonorchiasis infections are endemic. In western countries,it is very rare and the etiology is unknown. In this article,we report the first IPNB patient we encountered in our clinic and a literature review. The patient is a 38-yearold female with a history of choledocholithiasis who presented with obstructive jaundice. She was found to have a papillary mass at the junction of the right hepatic duct and common hepatic duct with six masses in the liver parenchyma. The immunophenotypic and histologic features of the tumor are consistent with IPNB,gastric subtype. The patient had a partial hepatectomy and has been receiving palliative chemotherapy. In a search of Pub Med database,we collected 354 IPNB patients reported in 22 articles. In these patients,52.8% were from Japan and 27.7% were from western countries including the United States(11.0%). The age of the patients ranged from 35 to 80 years old with an average of 64.6. Male/female ratio was 1.5. Macroscopically,57.5% of the tumors were in the left lobe and 29.5% were in the right lobe. The average size of the tumor were 4.2 cm at the time of diagnosis. Histologically,pancreato-biliary subtype accounted for 41.8%,intestinal 28.0%,gastric 13.5% and oncocytic 16%. An invasive component is most often present in the pancreato-biliary and gastric subtypes. Despite recent advanced technologies,diagnosis of IPNB is still challenging,especially in western countries due to its rarity. Defined clinicopathologic features are in demand for the accurate diagnosis and proper treatment. | Yaohong Tan Clara Milikowski Yanelba Toribio Adam Singer Claudia P Rojas Monica T Garcia-Buitrago | 2015 | World Journal of Gastroenterology2015，21，43： | 19 |
| 2 | Condensed tannin biosynthesis genes are regulated separately from other flavonoid biosynthesis genes in apple fruit skin显示文摘 | Adam M T Benjamin E U Robinson S P | 2006 | Plant Science2006，170，： | 1 |
| 3 | Rheological character-ization of animal fats and their mixtures with#2 fuel oil显示文摘 | GOODRUM J W GELLER D P ADAMS T T | 2003 | BiomassBioenergy2003，24，3： | 1 |
| 4 | Pharmacokinetlcs of floffenicol in veal calves 显示文摘 | VARMA K J ADAMS P E POWERS T E | 1986 | J Vet Phannacol Therap1986，9，： | 1 |
| 5 | Measurements of acute cerebral infarction: a clinical examination scale 显示文摘 | Brott T Adams H P Jr Olinger C P | 1989 | Stroke1989，20，7： | 1 |
| 6 | Sensitive de- tection of occult breast cancer by the reverse - transcriptase poly- merase chain reaction显示文摘 | DATI?A Y H ADAMS P T DROBYKI W R_ | 1994 | J Clin Oncol1994，12，6： | 1 |
| 7 | Nucleotide sequence, polymorphism, and evolution of ovine MHC class Ⅱ DQA genes 显示文摘 | Scott P C Gogolin-Ewens K J Adams T E | 1991 | Immunogenetics1991，34，2： | 1 |
| 8 | Healthy, Wealthy, and Wise? Tests for Direct Causal Paths Between Health and Socioeconomic Status 显示文摘 | ADAMS P HURD M MCFADDEN D MERRILL A RIBEI- RO T | 2003 | Journal of Econometrics2003，112，： | 1 |
| 9 | A fiber-opticDNA biosensor microarrary for the analysis of gene expression显示文摘 | Boles T C Adams C P | 1996 | Nat Biochnol1996，14，13： | 1 |
| 10 | Crystallography & NMR system: A new software suite for maeromoleeular structure determination显示文摘 | Brunger A T Adams P D Clore G M | 1998 | Aeta Crystallogr D Biol Crystallogr1998，54，5： | 1 |
| 11 | Pharmacokinetics of florfenicol in veal carves 显示文摘 | Varma K J Adams P E Powers T E | 1986 | Veterinary Pharmacology Therapie1986，，4： | 1 |
| 12 | A genetic basis for IFN-gamma production and T-bet expression in humans 显示文摘 | Hohler T Reuss E Adams P | 2005 | J Immunol2005，175，8： | 1 |
| 13 | Vitamin D-directed rheostatic regu- lation of monocyte antibacterial responses 显示文摘 | Adams J S Ren S Liu P T | 2009 | J lmmunol2009，182，7： | 1 |
| 14 | Potential taxonomic use of random amplified polymorphic DNA (RAPD):a case study in Brassica显示文摘 | Demeke T Adams R P Chibbar R | 1992 | Theoretical and Applied Genetics1992，84，： | 1 |
| 15 | Nucleotide sequence,polymorphism,and evolution of ovine MHC class II DQA genes显示文摘 | Scott P C Gogolin-Ewens K J Adams T E | 1991 | Immunogenetics1991，34，2： | 1 |
| 16 | The Electrical Properties of MIS Capacitors with AlN Gate Dielectrics显示文摘 | Adam T Kolodzey J Swann C P | 2001 | Applied Surface Science2001，428，： | 1 |
| 17 | The effect of mouth opening on the biomass and community structure of microphytobenthos in a small oligotrophic estuary显示文摘 | Skinner T Adams J Gama P | | 0，，1： | 1 |
| 18 | Single-post inductive obstacle in rectangular waveguide显示文摘 | Leviatan Y Li P G Adams A T | 1983 | IEEE transactions on microwave theory and techniques1983，，31： | 1 |
| 19 | Field response of alfalfa looper and cabbage looper moths (Lepidoptera: Noetuidac, Plusiinae) to single and binary blends of floral odorants显示文摘 | Landolt P J Adams T Zack R S | 2006 | Environmental Entomology2006，35，2： | 1 |
| 20 | Guidelineson diag- nosis and management of acute pulmonary embolism 显示文摘 | Adam T Chairperson Arnuaud P | 2008 | Eur Heart J2008，29，18： | 1 |
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