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| 1 | CPM抑制了由1,4NQ诱导的对骨肌肌质网SR钙通道RyR1的激活效应显示文摘利用7 -diethylamino -3 -(4' -maleimidylphenyl) -4 -methylcoumarin(CPM)甲基化钙通道RyR1上的特异敏感性硫醇的方法 ,对由1 ,4 -naphthoquinone(1,4NQ)诱导的双相性作用进行了研究 ,发现CPM能明显阻碍由1 ,4NQ诱导的对RyR1的激活 ,但对由1 ,4NQ产生的抑制没有明显作用。用经CPM预处理过和没有处理过的样品与1 ,4NQ温育后离心清洗 ,发现未经CPM处理的样品经激活和抑制浓度的1 ,4NQ温育后 ,离心清洗不能消除1 ,4NQ对RyR1的激活和抑制。而经CPM处理后的样品 ,在1 ,4NQ的激活浓度和抑制浓度下 ,离心清洗后未能观测到1 ,4NQ诱导的激活态 ,但抑制态仍然明显存在。以上结果说明 ,CPM所识别的特异活性硫醇参与了1 ,4NQ激活作用 :CPM与此硫醇发生甲基化作用 ,因此阻断了1 ,4NQ对RyR1上的激活部位硫醇发生作用 。 | 夏若虹 Abramson J.Jonathan 李莉 童华 姚松年 | 2002 | 生物物理学报2002，18，1： | 4 |
| 2 | Surgical Resection Versus Palliative Chemoradiotherapy for the Management of Pancreatic Cancer with Local Venous Invasion: A Decision Analysis显示文摘 | Michael A. Abramson Edward W. Swanson Edward E. Whang | 2009 | Journal of Gastrointestinal Surgery2009，，1： | 3 |
| 3 | Prevalence of Colorectal Cancer Surveillance for Ulcerative Colitis in an Integrated Health Care Delivery System显示文摘 | Fernando S. Velayos Liyan Liu James D. Lewis James E. Allison Nicole Flowers Susan Hutfless Oren Abramson Geraldine S. Perry Lisa J. Herrinton | 2010 | Gastroenterology2010，，5： | 3 |
| 4 | Detection of specific polymerase chain reaction product by utilizing the 5'-3' exonuclease activity of Thermus aquaticus DNA polymerase 显示文摘 | Holland PM Abramson RD Watson R | 1991 | Proc Natl Acad Sci U S A1991，88，16： | 3 |
| 5 | Underworld-GT Applied to Guangdong,a Tool to Explore the Geothermal Potential of the Crust显示文摘Geothermal energy potential is usually discussed in the context of conventional or engineered systems and at the scale of an individual reservoir. Whereas exploration for conventional reservoirs has been relatively easy,with expressions of resource found close to or even at the surface,exploration for non-conventional systems relies on temperature inherently increasing with depth and searching for favourable geological environments that maximise this increase. To utilitise the information we do have,we often assimilate available exploration data with models that capture the physics of the dominant underlying processes. Here,we discuss computational modelling approaches to exploration at a regional or crust scale,with application to geothermal reservoirs within basins or systems of basins. Target reservoirs have(at least) appropriate temperature,permeability and are at accessible depths. We discuss the software development approach that leads to effective use of the tool Underworld. We explore its role in the process of modelling,understanding computational error,importing and exporting geological knowledge as applied to the geological system underpinning the Guangdong Province,China. | Steve Quenette Yufei Xi John Mansour Louis Moresi David Abramson | 2015 | Journal of Earth Science2015，26，1： | 2 |
| 6 | Depressive symptoms and risk of functional decline and death in patients with heart failure显示文摘 | Kasl SV Abramson J | 2001 | J Am Coll Cardiol2001，38，1： | 1 |
| 7 | NCCN Clinical Practice Guidelines in Oncology: non-Hodgkin's lymphomas 显示文摘 | Zelenetz AD Abramson JS Advani RH | 2010 | J Natl Compr Canc Netw2010，8，3： | 1 |
| 8 | Dynamics of contained liquids: a personal odyssey 显示文摘 | Abramson H N | 2003 | Applied Mechanics Review2003，56，1： | 1 |
| 9 | Tissue expansion in children: a retrospective study of complications显示文摘 | Gibstein LA Abramson DL Bartlett RA | 1997 | Ann Plast Surg1997，38，4： | 1 |
| 10 | Use of nude mouse xenogratts as preclinical drug screens: in vivo activity of established chemotherapeutic agents against melanoma and ovarian carcinoma xenogratts 显示文摘 | Tactic R Rosen F Abramson I | 1987 | Cancer Treat Rep1987，71，3： | 1 |
| 11 | Prostaglandin E2 synthesis and secretion:the role of PGE2 synthases 显示文摘 | Park JY Pillinger MH Abramson SB | 2006 | Clin Immunol2006，119，： | 1 |
| 12 | Connective tissue growth factor mediates transforming growth factor beta-induced collagen synthesis: down-regulation by cAMP显示文摘 | Frazier KS Abramson S | 1999 | FASEB J1999，13，13： | 1 |
| 13 | The grid economy显示文摘 | David Abramson Srikumar Venugopal | 2005 | Proceedings of the IEEE2005，93，3： | 1 |
| 14 | High-speed drill noise and hearing: audiometric survey of 70 dentists显示文摘 | FORMAN-FRANCO B ABRAMSON A L STEIN T | 1978 | J Am DentAssoc1978，97，5： | 1 |
| 15 | Detection of specific polymerase chain reaction product by utilizing the 5′-3′exonoclease to thermos aquaticus DNA polymerase 显示文摘 | Holland P M Abramson R D Watson R | 1991 | Proc Natl Acd Sci USA1991，88，16： | 1 |
| 16 | A computational economy for grid computing and its implementation in the nimrod-g resource broker显示文摘 | ABRAMSON D BUUYA R GIDDY J | 2002 | Future Generation Computer Systems2002，18，8： | 1 |
| 17 | Detection of specific polymerase chain reaction product by utilizing the 5 '3 ' exonucleas activity of the thermos aquaticus DNA polymerase显示文摘 | Holland P M Abramson R D Watson R | 1991 | Pro Nat Aca Sci USA1991，88，6： | 1 |
| 18 | Allergen immunotherapy for asthma显示文摘 | Abramson MJ Puy RM Weiner JM | 2003 | Cochrane Database Syst Rev2003，，00： | 1 |
| 19 | Coronary vasospasm: a case report and review of the literature显示文摘 | Van Spall H G Overgaard C B Abramson B L | 2005 | Can J Cardiol2005，21，11： | 1 |
| 20 | Cyclooxygenase in biology and disease 显示文摘 | Dubois RN Abramson SB Crofford L | 1998 | FASEB J1998，12，12： | 1 |
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