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| 1 | IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treat- ment of Cancer Brain Tumor Group显示文摘 | van den Bent M J Dubbink HJ Marie Y Brandes AA Taphoorn MJ Wesseling P Frenay M Tijssen CC Lacombe D ldbaih A van Marion R Kros JM Dinjens WN Gorlia T. Sanson M. | 2010 | 中国神经肿瘤杂志2010，8，1： | 22 |
| 2 | 国际胃袖状切除专家共识:基于>12000手术病例的最佳操作指南显示文摘腹腔镜胃袖状切除术(1aparoscopic sleeve gastrectomy,LSG)系相对较新的减重手术方式。因其操作相对简单、治疗肥胖合并疾病及减重效果明显,逐步得以广泛接受。目前美国代谢与减重手术协会将其推荐为肥胖症治疗的单独标准术式。2011年3月25~26日, | 苏远涛 徐安安 朱江帆 Diaz AA Arvidsson D Baker RS Basso N Bellanger D Boza C El Mourad H France M Gagner M Galvao-Neto M Higa KD Himpens J Hutchinson CM Jacobs M Jorgensen JO Jossart G Lakdawala M Nguyen NT Nocca D Prager G Pomp A Ramos AC Rosenthal RJ Shah S Vix M Wittgrove A Zundel N | 2013 | 中国微创外科杂志2013，13，9： | 12 |
| 3 | Detection of dietary plant-based small RNAs in animals显示文摘 | Jian Yang Lisa M Farmer Abia AA Agyekum Kendal D Hirschi | 2015 | Cell Research2015，25，4： | 9 |
| 4 | Juvenile polyposis syndrome显示文摘Juvenile polyposis syndrome is a rare autosomal dominant syndrome characterized by multiple distinct juvenile polyps in the gastrointestinal tract and an increased risk of colorectal cancer.The cumulative life-time risk of colorectal cancer is 39% and the relative risk is 34.Juvenile polyps have a distinctive histology characterized by an abundance of edematous lamina propria with inflammatory cells and cystically dilated glands lined by cuboidal to columnar epithelium with reactive changes.Clinically,juvenile polyposis syndrome is defined by the presence of 5 or more juvenile polyps in the colorectum,juvenile polyps throughout the gastrointestinal tract or any number of juvenile polyps and a positive family history of juvenile polyposis.In about 50%-60% of patients diagnosed with juvenile polyposis syndrome a germline mutation in the SMAD4 or BMPR1A gene is found.Both genes play a role in the BMP/TGF-beta signalling pathway.It has been suggested that cancer in juvenile polyposis may develop through the socalled 'landscaper mechanism' where an abnormal stromal environment leads to neoplastic transformation of the adjacent epithelium and in the end invasive carcinoma.Recognition of this rare disorder is important for patients and their families with regard to treatment,follow-up and screening of at risk individuals.Each clinician confronted with the diagnosis of a juvenile polyp should therefore consider the possibility of juvenile polyposis syndrome.In addition,juvenile polyposis syndrome provides a unique model to study colorectal cancer pathogenesis in general and gives insight in the molecular genetic basis of cancer.This review discusses clinical manifestations,genetics,pathogenesis and management of juvenile polyposis syndrome. | Lodewijk AA Brosens Danielle Langeveld W Arnout van Hattem Francis M Giardiello G Johan A Offerhaus | 2011 | World Journal of Gastroenterology2011，17，44： | 7 |
| 5 | 血压变异性预测自发性脑出血患者的院内不良预后显示文摘越来越多的证据表明,较高的收缩压变异性(systolicblood pressure variability ,SBPV)可能与脑出血患者的不良预后相关。该研究探讨了 SB PV 与院内脑出血预后之间的关系。研究者在2个医疗系统中收集了10年的自发性脑出血患者的连续数据。记录人口统计学、病史、实验室测试、计算机断层扫描数据、院内治疗情况以及神经和功能评估。在入院后24h内获取血压记录。 | 刘青 叶鹏 Divani AA Liu X Di Napoli M Lattanzi S Ziai W James ML Jafarli A Jafari M Saver JL Hemphill JC Vespa PM Mayer SA Petersen A | 2019 | 中华高血压杂志2019，27，8： | 6 |
| 6 | 《认知行为疗法减轻耳鸣、听觉过敏及恐声症所致痛苦的现状》摘译显示文摘1耳鸣的定义和心理学影响耳鸣是没有外部声音刺激的情况下对声音的感知。耳鸣常见描述有:嗡嗡声、高音调噪声、口哨声、瀑布声、砂轮声、铃声、静电噪声等,大约20%的患者无法描述他们的耳鸣声。大多数耳鸣患者伴有某种程度的听力损失,但并非所有的听力损失患者都有耳鸣。英国最近一项针对在耳鸣和听觉过敏诊所就诊的445例患者的研究表明,耳鸣的响度与听力损失的严重程度有关。 | 余炎林(摘译) 张剑宁(审校) Aazh H Landgrebe M Danesh AA | 2021 | 听力学及言语疾病杂志2021，29，1： | 3 |
| 7 | Cardiorenal syndrome显示文摘 | Ronco C Haapio M House AA | | 0，，： | 2 |
| 8 | Water permeability of aquaporin-4 is decreased by protein kinase C and dopamine显示文摘 | Zelenina M Zelenin S Bondar AA | 2002 | Am J Physiol Renal Physiol2002，283，2： | 2 |
| 9 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 10 | Complications neuropathy:pathogenetic considerations显示文摘 | Greene DA Sima AA Stevens M J | | 0，，： | 2 |
| 11 | Correlation between Saccharomyces cerevisiae DNA in intestinal mucosal samples and anti-Saccharomyces cerevisiae antibodies in serum of patients with IBD显示文摘瞄准:调查在粘膜 S 的 ASCA 和存在之间的关联。在 CD, ulcerative (UC ) 病人和控制的一张人口的啤酒 DNA。方法:S。cerevisiae 特定的教材和一根荧光灯的探针为 5' exonuclease 实时 PCR (TaqMan ) 试金被设计,它是用为在实时的 PCR 产品的察觉的一根荧光灯标签的探针的一个同质的系统。我们在一组 76 煽动性的肠疾病(IBD ) 与 ASCA 调查结果分析了 PCR 结果的关系病人(31 CD, 45 UC ) 并且 22 健康控制(HC ) 。结果:ASCA (IgA 或 IgG ) 在 19 是积极的(61%) 有 CD 的病人, 12 (27%) 与 HC 的 UC 和没有。PCR 扩大在 10 从最后的结果被禁止并且排除(22%) UC 病人, 7 (22%) CD 病人,并且 6 (30%) HC。在里面仅仅, 15 粘膜取样, S。啤酒 DNA 被实时 PCR 检测,包括 7 (29%) 在 CD, 7 (19%) 在 UC, 1 (6%) 在 HC。在 4 CD 并且在 4 个 UC 病人, ASCA 和粘膜 S。啤酒是积极的。粘膜 S。啤酒在 3 UC,和 3 个 CD 病人在有否定 ASCA IgA 和 IgG 的联合是在场的。结论:自从 S 的存在,我们结束那。在结肠的粘膜活体检视标本的啤酒是很稀罕的, ASCA 是不大可能的被连续暴露向 S 解释。在粘膜的啤酒。因此, ASCA 形成必须在生命更早发生,层次在免疫学的此后仍然保持相对稳定易受影响的人。 | RC Mallant-Hent M Mooij BME von Blomberg RK Linskens AA van Bodegraven PHM Savelkoul | 2006 | World Journal of Gastroenterology2006，12，2： | 2 |
| 12 | 内皮细胞活化与高血压患者的认知功能有关显示文摘高血压与认知功能障碍和痴呆的发生有关,可能是因为高血压是引发脑损伤的一个重要危险因素,脑损伤是脑小血管病的一种表现。已发现内皮细胞活化和炎症在脑小血管病的发病机制中发挥重要作用。该研究调查以几种血管标志物为基础的内皮细胞活化或炎症的综合积分是否与原发性高血压患者3年后的认知功能有关。 | Uiterwijk R Huijts M Staals J Rouhl RP De Leeuw PW Kroon AA Van Oostenbrugge RJ 陈云 叶鹏 | 2016 | 中华高血压杂志2016，24，6： | 2 |
| 13 | Myoblast transplantation for heart failure 显示文摘 | Menasche P Hagege AA Scorsin M | 2001 | Lancet2001，357，9252： | 1 |
| 14 | Hormonal control of androgen receptor function through Sirtl 显示文摘 | Fu M Liu M Sauve AA | 2006 | Mol Cell Biol2006，26，21： | 1 |
| 15 | Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation 显示文摘 | Babcock AA Wirenfeldt M Holm T | 2006 | J Neurosci2006，26，12： | 1 |
| 16 | Survivin promoter polymorphism and cervical carcinogenesis显示文摘 | Borbely AA Murvai M Szarka K | 2007 | J Clin Patho12007，60，3： | 1 |
| 17 | Genome-wide RNAi analysis of growth and viability in drosophila cells 显示文摘 | Boutros M Kiger AA Armknecht S | 2004 | Science2004，303，5659： | 1 |
| 18 | Increasing insulin resistance is associated with a decrease in leydig cell testosterone secretion in men显示文摘 | Hardin M Dwyer AA | 2005 | Clin Endocrinol Metab2005，90，： | 1 |
| 19 | Stryland Time-resolvedZ-scan measuremelRs of optical nonlinearties显示文摘 | HEIK-BAHAE M SAID AA | 1994 | Optical society of America1994，11，6： | 1 |
| 20 | Urinary interleukin-18 is an acute kidney injury biomarker in critically ill children显示文摘 | Washburn KK Zappitelli M Arikan AA | 2008 | Nephrol Dial Transplant2008，23，2： | 1 |
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