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402篇 您的检索式:作者名="A Smart"
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1Radiofrequency ablation for early oesophageal squamous neoplasia:Outcomes form United Kingdom registry显示文摘AIM:To report outcomes on patients undergoing radiofrequency ablation(RFA)for early oesophageal squamous neoplasia from a National Registry.METHODS:A Prospective cohort study from 8 tertiary referral centres in the United Kingdom.Patients with squamous high grade dysplasia(HGD)and early squamous cell carcinoma(ESCC)confined to the mucosa were treated.Visible lesions were removed by endoscopic mucosal resection(EMR)before RFA.Following initial RFA treatment,patients were followed up 3monthly.Residual flat dysplasia was treated with RFA until complete reversal dysplasia(CR-D)was achieved or progression to invasive Squamous cell cancer defined as infiltration into the submucosa layer or beyond.The main outcome measures were CR-D at 12 mo from start of treatment,long term durability,progression to cancer and adverse events.RESULTS:Twenty patients with squamous HGD/ESCC completed treatment protocol.Five patients(25%)had EMR before starting RFA treatment.CR-D was 50%at12 mo with a median of 1 RFA treatment,mean 1.5(range 1-3).Two further patients achieved CR-D with repeat RFA after this time.Eighty per cent with CR-D remain dysplasia free at latest biopsy,with median follow up 24 mo(IQR 17-54).Six of 20 patients(30%)progressed to invasive cancer at 1 year.Four patients(20%)required endoscopic dilatations for symptomatic structuring after treatment.Two of these patients have required serial dilatations thereafter for symptomatic dysphagia with a median of 4 dilatations per patient.The other 2 patients required only a single dilatation to achieve an adequate symptomatic response.One patient developed cancer during follow up after end of treatment protocol.CONCLUSION:The role of RFA in these patients re-mains unclear.In our series 50%patients responded at12 mo.These figures are lower than limited published data.Rehan J Haidry Mohammed A Butt Jason Dunn Matthew Banks Abhinav Gupta Howard Smart Pradeep Bhandari Lesley Ann Smith Robert Willert Grant Fullarton Morris John Massimo Di Pietro Ian Penman Marco Novelli Laurence B Lovat 2013World Journal of Gastroenterology2013,19,36:7
2Annual growth banding in a cave stalagmite显示文摘Baker A Smart P Edwards R 1993Nature1993,364,:2
3GDF11 modulates NGN3+ islet progenitor cell number and promotes beta-cell differentiation in pancreas development显示文摘Harmon E B Apelqvist A A Smart N G 2004Development2004,131,24:1
4High-resolution records of soil humification and paleoclimate change from variations in speleothem luminescence excitation and emission wavelengths 显示文摘Baker A Genty D Smart P 1998Geology1998,26,10:1
5Extending theinformation-theoretic measures of the dynamic com-plexity of manufacturing systems 显示文摘Smart J Calinescu A Huatuco H L 2013International Journal of Production Research2013,51,2:1
6Optimization of a small-scale fermentation test to predict the premature yeast flocculation potential of malts显示文摘Panteloglou A G Box W G Smart K A 2010J Inst Brew2010,116,4:1
7Lactoferricin, a new antimicrobial peptide显示文摘E M Jones A Smart G Bloomberg 1994Joumal of Applied Bacteriology1994,77,:1
8Efficacy of Muscodor albus forthe control of Phytophthora blight of sweet pepper and butternutsquash 显示文摘Camp A R Dillard H R Smart C D 2008Plant Disease2008,92,11:1
9Reverse auctions as a support mechanism in flexible supply chains显示文摘Smart A Harrison A 2002International Journal of Logistics: Research and Applications2002,5,3:1
10L-Proline Functional- ized Polymers Prepared by RAFT Polymerization and Their Assemblies as Supported Organoeatalysts显示文摘Lu A Smart T P Epps T H 2011Mac- romo12011,44,18:1
11Online reverse auctions and their role in buyer supplier relationships显示文摘 Harrison A 2003Journal of Purchasing and Supply Management2003,9,:1
12Thiopurine methyltransferase activity in a sample population of black subjects in Florida显示文摘ones CD Smart C Titus A 1993Clin Pharmacol Ther1993,53,3:1
13Annual growth banding in a cave stalagmite显示文摘Baker A Smart P L Edwards R L Richards D A 1993Nature1993,364,:1
14The influence of sodium carbonate in sodium aluminosilicate crystallization and solubility in sodium aluminate solutions显示文摘ZHENG K L GERSON A R ADDAL-MENSAH J SMART R S C 1997J Crystal Growth1997,171,:1
15Caveolins, liquidordered domains and signal transduction 显示文摘Smart E J Graf G A McNiven M A 1999Molecular and Cellular Biology1999,19,:1
16Transcriptional regulation of hepat-ic stellate cell activation显示文摘Mann D A Smart D E 2002Gut2002,50,6:1
17Annual growth banding in a cave stalagmite显示文摘Baker A Smart P L Edwards R L 1993Nature1993,364,:1
18Speleothem luminescence intensity and spectral characteristics: Signal calibration and a record of palaeovegetation change 显示文摘Baker A Barnes W Smart P 1996Chemical Geology1996,130,:1
19Personal relations and divergent economies: a case study of Hong Kong ivestment, in south China显示文摘mart J Smart A 1991Interna- tiond of Urban and Regional Research1991,5,2:1
20Pratical considerations in photon correlation experiments显示文摘Brown R G W Smart A E 1997Appl Opt1997,36,30:1
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