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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Multimodality treatment in locore-gional gynecological cancer: cervical cancer treatment update显示文摘 | Poveda A Gonzalez-Martin A | 2008 | Ann Oncol2008，19，7： | 1 |
| 3 | Leucocytoclastic vasculitis associated with golimumab 显示文摘 | pAMIES A CASTRO S POVEDA MJ | 2013 | Rheumatology (Oxford)2013，52，10： | 1 |
| 4 | Economic development and growth in Colombia:an empirical analysis with super-efficiency DEA and panel data显示文摘 | Poveda A C | 2011 | Sociol-Economic Planning Sciences2011，45，4： | 1 |
| 5 | Analog Current-mode Implementation of a One-cycle Integrated Controller for Switching Power Converters显示文摘 | E Alarcon A Poveda | 2001 | IEEE Transactions on Power Electronics2001，，1： | 1 |
| 6 | Anti-angiopoietin therapy with trebananib for recurrent ovarian cancer (TRINOVA-1): a randomised, multicentre, double-blind, placebo-controlled phase 3 trial 显示文摘 | Monk B J Poveda A Vergote I | 2014 | Lancet Oncol2014，15，8： | 1 |
| 7 | Gemcitabine in patients with ovarian cancer显示文摘 | Poveda A | 2005 | Cancer Treat Rev2005，，4： | 1 |
| 8 | Economic development and growth in Colombia: an empirical analysis with super-efficiency DEA and panel data显示文摘 | Poveda A C | 2011 | Socio-Economie Planning Sciences2011，45，4： | 1 |
| 9 | Gemcitabine in patients with ovarian cancer 显示文摘 | Poveda A | 2005 | Cancer Treat Rev2005，，4： | 1 |
| 10 | A randomized phase II (RP2) trial of ridaforolimus (R) compared with progestin (P) or chemotherapy (C) in female adult patients with advanced endometrial carcinoma显示文摘 | Oza A M Poveda A Clamp AR | 2011 | J Clin Oncol2011，29，24： | 1 |
| 11 | Contribution of nitric oxide to exercise-induced changes in healthy volunteers:effects of acute exercise and long-term physical training显示文摘 | Poveda JJ Riestra A Salas E | 1997 | Eur J Clin Invest1997，27，11： | 1 |
| 12 | Multimodality treatment in locore- gional gynecological cancer:cervical cancer treatment update 显示文摘 | Poveda A Gonzalez-Martin A | 2008 | Ann Oneol2008，19，7： | 1 |
| 13 | Spanish Group for Sarcoma Research: Deletions affecting codons 557-558 of the c-KIT gene indicate a poor prognosis in patients with com- pletely resected gastrointestinal stromal tumors: a study by the Spanish Group for Sarcoma Research (GEIS) 显示文摘 | Martin J Poveda A Llombart-Bosch A | 2005 | J Clin On- col2005，23，25： | 1 |
| 14 | Intraoperative monito- ring of the recurrent laryngeal nerve during thyroidectomy : a stan- dardlized approach part2 显示文摘 | Poveda MCD Dionigi G Sitgessrra A | 2012 | Endocr Surg2012，4，1： | 1 |
| 15 | Treatmentguidelines in ovarian cancer 显示文摘 | Poveda V A Casado H A Cervantes R A | 2007 | Clin Transl Oncol2007，9，5： | 1 |
| 16 | Circulating tumor cells predict progression free survival and overall survival in patients with relapsed/recurrent advanced ovarian cancer 显示文摘 | Poveda A Kaye SB McCormack R | 2011 | Gynecol Oncol2011，122，3： | 1 |
| 17 | Agerelated responses of vasoactive factors during acute exercise显示文摘 | Poveda J J Berrazueta J R Ochoteco A | 1998 | Horm Metab Res1998，30，11： | 1 |
| 18 | Fenta nyl-trazodone- paracetamol triple drug combination mul timodal analgesia in a mouse model of visceral pain显示文摘 | Ferndndez- DuenasV Poveda R Ferndndez A | 2011 | Phar macol BiochemBehav2011，98，3： | 1 |
| 19 | Model parametric Hamiltonians and bonding theoretical tools in simulation of catalytic reaction steps:Hydrotreatment of oil components显示文摘 | Poveda M Sierraalta A | 1997 | Journal of Molecular Catalysis A:Chemical1997，119，： | 1 |
| 20 | Management of recurrent ovarian cancer with systemic therapy显示文摘 | Poveda A | 2007 | EJC2007，，5： | 1 |
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