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| 1 | Proposal of an ultrasonographic classification for hepatic alveolar echinococcosis: Echinococcosis multilocularis Ulm classification-ultrasound显示文摘AIM: To establish an ultrasonographic classification based on a large sample of patients with confirmed hepatic alveolar echinococcosis(AE).METHODS: Clinical data and ultrasonography(US) findings of 185 patients(100 males; 85 females; mean age at diagnosis: 51.4 ± 17.6 years; mean age at time of US examination: 58.7 ± 18.2 years) were retrospectively reviewed with respect to the US morphology of hepatic AE lesions. The sonomorphological findings were grouped according to a five-part classification scheme.RESULTS: Application of the new classification resulted in the following distribution of sonomorphological patterns among the patients examined: hailstorm(54.1%); pseudocystic(13.5%); ossification(13.0%); hemangioma-like(8.1%); and metastasis-like(6.5%). Only 4.9% of lesions could not be assigned to a sonomorphological pattern.CONCLUSION: The sonomorphological classification proposed in the present study facilitates the diagnosis,interpretation and comparison of hepatic alveolar echinococcosis in routine practice and in the context of scientific studies. | Wolfgang Kratzer Beate Gruener Tanja EM Kaltenbach Sarina Ansari-Bitzenberger Peter Kern Michael Fuchs Richard A Mason Thomas FE Barth Mark M Haenle Andreas Hillenbrand Suemeyra Oeztuerk Tilmann Graeter | 2015 | World Journal of Gastroenterology2015,21,43: | 16 |
| 2 | WONCA研究论文摘要汇编——老年患者因患多种疾病接受全科诊疗时的自感健康状况:一项在德国进行的横断面研究显示文摘背景随着预期寿命的延长,罹患多种疾病的人数也在上升。然而在患有多种疾病的人群中,了解生活质量健康影响因素者寥寥无几。本试验旨在确定老年患者因患多种疾病接受基层医疗服务时,与其自感健康状况(SRH)相关的影响因素。方法从德国境内的8个研究中心158个全科医疗点中,选出因患多种疾病接受基层医疗服务、年龄65~85岁的3 189例老年患者进行横断面研究。通过面对面的访谈,收集有关患病情况、危险因素、智力水平、机体功能状态以及社会经济状况的资料。 | Nützel A Dahlhaus A Fuchs A 周淑新 | 2014 | 中国全科医学2014,17,17: | 10 |
| 3 | 维生素D对心力衰竭患者全因死亡率的影响:4000U/d维生素D口服3年随机临床试验结果显示文摘循环25-羟基维生素D[25-hydroxyvitamin D,25(OH)D]〈75nmol/L与死亡率风险的非线性增加相关。这种低25(OH)D水平在心力衰竭患者中很常见。因此,Zittermann等进行研究检查口服维生素D补充剂能否降低晚期心力衰竭患者的死亡率。 | 刘莉 叶鹏 Zittermann A Ernst JB Prokop S Fuchs U Dreier J Kuhn J Knabbe C Birschmann I Schulz U Berthold HK Pilz S Gouni-Berthold I Gummert JF Dittrich M Brgermann J | 2017 | 中华高血压杂志2017,25,10: | 7 |
| 4 | 标准辅助化疗基础上增加塞来昔布或安慰剂对Ⅲ期结肠癌患者无复发生存的疗效对比研究:CALGB/SWOG 80702(Alliance)随机对照研究显示文摘背景:既往观察性和随机对照研究已表明阿司匹林和环氧化酶-2(COX-2)抑制剂可降低肠道息肉和肠癌的发生风险。COX-2抑制剂塞来昔布治疗非转移性结肠癌的效果尚未明确。目的:本研究旨在明确FOLFOX辅助化疗基础上增加塞来昔布是否能提高Ⅲ期结肠癌患者的无复发生存率。方法:本研究为在美国、加拿大的654个中心开展的采用2×2析因设计的Ⅲ期临床研究,从2010年6月至2015年11月共纳入2526例Ⅲ期结肠癌患者,随访时间截止为2020年8月10日。以化疗时长和是否接受塞来昔布治疗作为2个随机因素,入组患者被随机分配接受3个月或6个月的FOLFOX辅助化疗(每两周1次)及随机接受联合3年塞来昔布(400 mg QD,n=1263)或安慰剂(n=1261)治疗。主要终点测量指标为3年无复发生存率(DFS),次要终点测量指标包括总生存、不良反应及心血管特异性不良事件。本次仅报道以是否接受塞来昔布治疗的随机分组研究结果。结果:入组患者平均年龄(61±11)岁,1134例(44.9%)为女性,最终2524例被纳入初步分析。患者治疗方案依从性(即接受塞来昔布或安慰剂治疗2.75年以上或持续治疗至复发、死亡或不可接受的不良事件)在塞来昔布组和安慰剂组分别为70.8%和69.9%。经过6年中位随访期,塞来昔布组和安慰剂组各有337例和363例患者出现疾病复发或死亡,3年无复发生率分别为76.3%和73.4%(疾病复发或死亡风险比HR=0.89,95%CI:0.76~1.03,P=0.12)。塞来昔布治疗对DFS的影响不会因辅助化疗时长(3个月或6个月)而存在差异(交互作用P=0.61)。两组5年生存率分别为84.3%和81.6%(死亡风险比HR=0.86,95%CI:0.72~1.04,P=0.13)。任何级别的高血压病发生率在塞来昔布组和安慰剂组分别为14.6%和10.9%,而2级或以上肌酐水平升高的发生率在两组分别为1.7%和0.5%。结论:对于Ⅲ期结肠癌患者,在标准辅助化疗的基础上联合3年塞来昔布治疗与安慰剂比较,对患者无复发生存率的改善不明显。 | 邱萌 MEYERHARDT J A SHI Q FUCHS C S | 2021 | 结直肠肛门外科2021,27,3: | 6 |
| 5 | Valeur Deficients Asymptotiques Des Functions Meromorphes显示文摘 | Edrei A Fuchs W H J | 1959 | Comment Math Helv1959,,33: | 2 |
| 6 | Sampling of aerosols显示文摘 | FUCHS N A | 1975 | Atmospheric Environment1975,9,8: | 1 |
| 7 | Klf4 is a transcription factor required for establishing the barrier function of the skin 显示文摘 | SEGRE J A BAUER C FUCHS E | 1999 | Nature Genetics1999,22,4: | 1 |
| 8 | Risk factors for pediattic ventriculoperitoneal shunt infection and predictors of infectious pathogens 显示文摘 | McGirt M J Zaas A Fuchs HE | 2003 | Clin Infect Dis2003,36,7: | 1 |
| 9 | Utility of DNA amplified by degenerate oligonucleotide-primed PCR (DOP-PCR) from the total genome and defined chromosomal regions of field bean显示文摘 | PICH U Houben A Fuchs J | 1994 | Mol Gen Genet1994,24,3: | 1 |
| 10 | Tissueengineering:a 21st century solution to surgical recon-struction显示文摘 | FUCHS J R NASSERI B A VACANTI J P | 2001 | The Annals of Thoracic Surgery2001,72,2: | 1 |
| 11 | Parval- bumin, a cross-reactive fish allergen, contains IgE-binding epitopes sensitive to periodate treatment and Ca^2+ depletion 显示文摘 | Bugajska-Schretter A Elfman L Fuchs T | 1998 | The Journal of Allergy and Clin- ical Immunology1998,101,1: | 1 |
| 12 | A feedback loop comprising lin-28 and let-7 controls pre-let-7maturation during neural stem-cell commitment 显示文摘 | Rybak A Fuchs H Smirnova L Brandt C Pohl EE Nitsch R etal | 2008 | Nat CellBioi2008,10,8: | 1 |
| 13 | Neutrophil extracellular trap(NET)impact on deep vein thrombosis显示文摘 | Fuchs TA Brill A Wagner DD | | 0,,: | 1 |
| 14 | Activation of the Raf-MEK-ERK pathway iS r~quired for neutrophil extracellular trap formation 显示文摘 | Hakkim A Fuchs TA Martinez NE | 2011 | Nat Chem Biol2011,7,2: | 1 |
| 15 | The Human Formin-binding Protein 17(FBP17)Interacts with Sorting Nexin,SNX2,and is an MLL-fusion Partner in Acute Myelogeneous Leukemia显示文摘 | FUCHS U REHKAMP G HAAS O A | 2001 | Proc Natl Acad Sci USA2001,98,15: | 1 |
| 16 | A supraomohyoidal plexus block designed to avoid complications显示文摘 | Feigl G Fuchs A Gries M | 2006 | Surg Radiol Anat2006,28,4: | 1 |
| 17 | Water condensation in hydrophobic nanopores显示文摘 | Desbiens N Demachy I Fuchs A H | 2005 | Angewandte Chemie-Intemational Edition2005,44,33: | 1 |
| 18 | Multiple regions of alpha-synuclein are associated with Parkinson′s disease显示文摘 | MUELLER J C FUCHS J HOFER A | | 0,,04: | 1 |
| 19 | Reproducibility of pulse wave velocity and augmentation index measured by pulse wave analysis显示文摘 | Wilkinson I B Fuchs S A Jansen I M | | 0,,12: | 1 |
| 20 | Implementation of a national nuchal translucency education and quality monitoring program显示文摘 | D’Alton ME Fuchs KM Abuhammad A | 2014 | Obstet Gynecol2014,123,1: | 1 |