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| 1 | Successful photodynamic therapy for biliary papillomatosis:A case report显示文摘Papillomatosis of the bile duct is a rare disease with a high risk of malignant transformation. Therapeutical options include partial hepatectomy and liver transplantation. A previously healthy 65-years old male developed jaundice and right upper abdominal quadrant pain in 1996. A villous adenoma of the distal bile duct was diagnosed. A Whipple procedure was performed. In 2002 the patient turned symptomatic again. Another adenoma was found in the right hepatic duct resulting in a right hepatectomy. Two years later the patient again developed cholestasis. After drainage of the left hepatic duct with a percutaneous transhepatic cholangial drainage (PTCD) catheter, a recurrent biliary adenomatosis was diagnosed by cholangioscopy. As there was no surgical option left, the patient received photodynamic therapy (PDT) for the recurrent biliary papillomatosis. Three mo after he received further photodynamic therapies, the bile duct epithelium appeared normal and the patient had no signs of adenomatosis, both macroscopically and histologically. The follow-up cholangioscopy in late 2005 revealed only a small papilloma without the need for intervention. In early 2006, the patient died of multi organ failure without signs of extrahepatic cholestasis or cholangitis at the age of 75, 10 years after the diagnosis of biliary papillomatosis was established. The patient exceeded the average life expectancy of patients with biliary papillomatosis by far. Thus, PDT might be a sufficient therapeutic option for recurrent papillomatosis patients with no significant side effects. | Lars P Bechmann Philip Hilgard Andrea Frilling Brigitte Schumacher Hideo A Baba Guido Gerken Thomas Zoepf | 2008 | World Journal of Gastroenterology2008，14，26： | 7 |
| 2 | Neuroendocrine tumor disease: an evolving landscape 显示文摘 | Frilling A AkerstrSm G Falconi M | 2012 | Endocr Relat Cancer2012，19，5： | 1 |
| 3 | Increased major histocompatibility complex (MHC) expression in nontoxic goiters is associated with iodide depletion,enhanced ability of the follicular thyroglobulin to increase MHC gene expression,and thyroid autoantibodies显示文摘 | Schuppert F Ehrenthal D Frilling A | 2000 | J Clin Endocrinol Metab2000，85，2： | 1 |
| 4 | Resectability of hepato- cellular carcinoma: evaluation of 333 consecutive cases at a single hepatobiliary specialty center and systematic review of the literature 显示文摘 | Sotiropoulos GC Lang H Frilling A | 2006 | Hepatogastroenterology2006，53，69： | 1 |
| 5 | Timing and risk factors of hepate- ctomy in the management of complications following laparoscopic cholecystectomy 显示文摘 | Li J Frilling A Nadalin S | 2012 | J astrointest Surg2012，16，： | 1 |
| 6 | A perspective on non-catalytic Src homology (SH) adaptor signalling proteins显示文摘 | Reebye V Frilling A Hajitou A | 2012 | Cell Signal2012，24，2： | 1 |
| 7 | Resectability of hep-atocellular carcinoma:evaluation of 333 consecutive cases at a single hepatobiliary specialty center and systematic review of the literature显示文摘 | Sotiropoulos GC Lang H Frilling A | | 0，，69： | 1 |
| 8 | Transactivation deficient? TAp73 acts as an oncogene显示文摘 | Stiewe T Zimmermann S Frilling A | 2002 | Cancer Res2002，62，13： | 1 |
| 9 | Living donor liver transplantation in adults显示文摘 | BROELSCH CE FRILLING A TESTA G | 2003 | Eur Gastroenterol Hepatol2003，15，： | 1 |
| 10 | Value of preoperative diagnostic modalities in patients with recurrent thyroid carcinoma 显示文摘 | FRILLING A GORGES R TECKLENBORG K | 2000 | Surgery2000，128，4： | 1 |
| 11 | Resectability of hepatocellular careinoma:evaluation of 333 consecutive cases at a single hepatobiliary specialty center and systematic review of the literature显示文摘 | Sotiropoulos GC Lang H Frilling A | 2006 | Hepatogastroenterology2006，53，69： | 1 |
| 12 | Management of concomitant hepatic artery injury in patients with iatrogenic major bile duct injury after laparoscopic cholecysteetomy显示文摘 | Li J Frilling A Nadalin S | 2008 | Brit J Surg2008，95，： | 1 |
| 13 | Major bile duct injuries after laparoscopic cholecystectomy: a tertiary center experience 显示文摘 | Frilling A Li J Weber F | 2004 | J Gastrointest Surg2004，8，： | 1 |
| 14 | Major bile duct injuries after laparoscopic cholecystectomy:a tertiary center experience显示文摘 | Frilling A Li J Weber F | 2004 | J Gastrointest Surg2004，8，6： | 1 |
| 15 | Transactivation deficient delta TA p73 acts as an oncogene显示文摘 | Stiewe T Zimmermann S Frilling A | 2002 | Cancer Res2002，62，13： | 1 |
| 16 | Gallblader endometriosis as a cause of occult bleeding显示文摘A 17-year-old girl with colicky abdominal pain andchronic anemia presented to the gastrointestinal serviceof the University Hospital of Essen. In the routineworkup, there were no pathological findings despitethe anemia. Because of the fluctuation of symptomswith a climax at the time of menstruation, consecutiveultrasound studies were performed revealing a visiblemass inside the gallbladder. This finding was confirmedby a magnetic resonance imaging (MRI) study performedat the same time. Because of the severe anemia by thattime, a cholecystectomy was performed, and histologyreconfirmed the diagnosis of isolated gallbladderendometriosis. The patient recovered well and has hadno recurrence of the disease to date. | K Saadat-Gilani L Bechmann A Frilling G Gerken A Canbay | 2007 | World Journal of Gastroenterology2007，13，33： | 1 |
| 17 | Major bile duct injuries after laparoscopic cholecystectomy:a tertiary center experience显示文摘 | Frilling A Li J Weber F | 2004 | J Gastrointest Surg2004，8，6： | 1 |
| 18 | Management of concomitant hepatic artery injury in patients with iatrogenic major bile duct injury after laparoscopie cholecystectomy 显示文摘 | Li J Frilling A Nadalin S | 2008 | Br J Surg2008，95，： | 1 |
| 19 | Recommendations for management of patients with neuroendocrine liver metastases显示文摘 | Frilling A Modlin IM Kidd M | 2014 | Lancet Oncol2014，15，1： | 1 |
| 20 | Neuroendocrine tumor disease : an evolving landscape 显示文摘 | Frilling A Akerstrom G Falconi M | 2012 | Endocr-Relat Cancer2012，19，5： | 1 |
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