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| 1 | 抗氧化水凝胶的研究进展显示文摘活性氧(ROS)是人体代谢过程中的重要中间产物,对维持人类正常生理活动起着关键作用,但其过度表达会引起一系列炎症反应,从而导致相关疾病的发生。近年来,随着对活性氧机理研究的深入,利用抗氧化材料清除ROS逐渐成为治疗炎症疾病的重要策略。其中,抗氧化水凝胶因其突出的生物相似性与多功能性,被视作清除体内ROS的重要材料之一。总结了目前抗氧化水凝胶的研究进展,包括材料的抗氧化机理、具体制备方法及其在生物医学领域的具体应用,并对抗氧化水凝胶的未来发展进行了展望。 | 陈鹏 杨凤英 顾志鹏 李乙文 | 2021 | 功能高分子学报2021，34，2： | 4 |
| 2 | A multifunctional biomedical patch based on hyperbranched epoxy polymer and MXene显示文摘Biomedical patches play fundamental roles in various applications such as wound closure and tissue regeneration.The hybrid patches integrating versatile properties will prominently improve the therapeutic effects in clinical applications.Herein,an epoxy network loading curcumin and Ti3 C2 TxMXenes were developed as a hybrid biomedical patch.The hybrid patch was basically prepared through an epoxy/thiol curing chemistry,and its topological structure can be destructed and rearranged as a vitrimer does due to the active transesterification at high temperature.The resulted hybrid patch exhibits shape-morphing capability,multi-substrate adhesion,self-healing ability,and photothermal effects under 980 nm near infrared(NIR).Additionally,the asprepared hybrid patch possesses strong UV-shielding,excellent oxidation resistance(ROS scavenging efficiency was 89.3%in3 min),highly effective antibacterial vitality(more than 99%)against S.aureus and E.coli,and good cytocompatibility.As a proof of concept,the present multifunctional hybrid patch broadens the potential applications in the biomedical field. | ZOU Yang JIN Xin ZHANG XiaoPing KONG XiaoLing ZHANG Qian XIE XianHua LIU ChangJun KE LinNan LIU WenGuang WANG Wei | 2021 | Science China(Technological Sciences)2021，64，12： | 2 |
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