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		题名	作者	年代	出处	被引量
	1	Global histone post-translational modifications and cancer:Biomarkers for diagnosis,prognosis and treatment?显示文摘Global alterations in epigenetic landscape are now recognized as a hallmark of cancer. Epigenetic mechanismssuch as DNA methylation,histone modifications,nucleosome positioning and non-coding RNAs are proven to have strong association with cancer. In particular,covalent post-translational modifications of histone proteins are known to play an important role in chromatin remodeling and thereby in regulation of gene expression. Further,histone modifications have also been associated with different aspects of carcinogenesis and have been studied for their role in the better management of cancer patients. In this review,we will explore and discuss how histone modifications are involved in cancer diagnosis,prognosis and treatment.	Shafqat Ali Khan Divya Reddy Sanjay Gupta	2015	World Journal of Biological Chemistry2015，6，4：	4
	2	H3K27甲基化与EZH2在B细胞非霍奇金淋巴瘤中表观遗传调控的研究进展显示文摘异常的组蛋白修饰与DNA甲基化是表观遗传学研究的重要领域,两者相互作用可导致特定基因的转录激活或抑制。H3K27的甲基化水平及其甲基转移酶EZH2可能与B细胞非霍奇金淋巴瘤(B-cell NHL)的特殊分型及不良预后密切相关。本文着重介绍H3K27me3与EZH2在B细胞非霍奇金淋巴瘤中的发生和发展过程的作用及相应机制。	邓玉洁朱伟峰陈刚陈君敏	2015	肿瘤防治研究2015，42，12：	1

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