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| 1 | Surgical management of polycystic liver disease显示文摘Adult polycystic liver disease (PCLD) is an autosomal dominant condition commonly associated with autosomal dominant polycystic kidney disease (ADPKD). However in the last decade, it has been recognized that there is a distinct form of autosomal dominant PCLD that arises without concomitant ADPKD. Early knowledge of the pathogenesis was gained from the study of hepatic cysts in patients with ADPKD. Bile duct overgrowth after embryogenesis results in cystic hepatic dilatations that are known as biliary microhamartomas or von Meyenburg complexes. Further dilatation arises from cellular proliferation and fluid secretion into these cysts. There is a variable, broad spectrum of manifestations of PCLD. Although PCLD is most often asymptomatic, massive hepatomegaly can lead to disabling symptoms of abdominal pain, early satiety, persistent nausea, dyspnea, ascites, biliary obstruction, and lower body edema. Complications of PCLD include cyst rupture and cyst infection. Also, there are associated medical problems, especially intracranial aneurysms and valvular heart disease, which clinicians need to be aware of and evaluate in patients with PCLD. In asymptomatic patients, no treatment is indicated for PCLD. In the symptomatic patient, surgical therapy is the mainstay of treatment tailored to the extent of disease for each patient. Management options include cyst aspiration and sclerosis, open or laparoscopic fenestration, liver resection with fenestration, and liver transplantation. The surgical literature discussing treatment of PCLD, including techniques, outcomes, and complication rates, are summarized in this review. | Robert T Russell C Wright Pinson | 2007 | World Journal of Gastroenterology2007，13，38： | 20 |
| 2 | 人类血压测量方法:美国心脏协会科学声明显示文摘准确的血压测量对高血压诊断与治疗至关重要。该文是美国心脏协会关于人类血压测量的最新科学声明。业已证实,在诊室许多电子血压计可以准确测量血压,同时减少与听诊法有关的人为误差。即使没有一个观察者在场,全自动电子血压计也可以通过多次测量提供较听诊法更准确的血压测量值。研究表明诊室外所测血压与诊室血压比较存在实质性差别。目前认为动态血压监测是诊室外血压评估的参考标准,当动态血压监测不可行或患者不能耐受时,家庭血压监测则是一个替代方法。 | 赵狄(摘译) 练桂丽(审校) Muntner P Shimbo D Carey RM Charleston JB Gaillard T Misra S Myers MG Ogedegbe G Schwartz JE Townsend RR Urbina EM Viera AJ White WB Wright JT Jr | 2019 | 中华高血压杂志2019，27，6： | 16 |
| 3 | 用InSAR数据得到的鲜水河断裂西北段地震间滑动速率显示文摘鲜水河断裂是青藏高原东部边缘附近的高活动性走滑断层系统。我们使用多干涉图方法由ERS-1/2和欧洲环境卫星所获得的十年SAR数据来构建由于鲜水河西北段地震间应变积累而产生的视距形变速率图。该速率图显示了与断层有关的清晰的形变梯度,但是从地表断层迹线看稍向东偏移。通过使用蒙特-卡洛方法对InSAR速率图和GPS数据的共同反演,当锁定深度为3~6km时,以90%置信水平估算出滑动速率为9~12mm/a。此滑动速率与全新世断层滑动速率及历史地震相吻合。我们的结果也揭示不存在显著的跨断层拉伸。将来,上升和下降轨道得出的InSAR数据可能会进一步约束此断层的3D断层滑动速率。 | Wang H Wright T J Biggs J 周平博 | 2013 | 国际地震动态2013，，3： | 4 |
| 4 | 儿童癫痫中的神经元抗体:临床特征和未经免疫治疗的历史队列远期预后显示文摘神经元细胞表面抗体在自身免疫性脑炎的发病中起着明确的作用;早期诊断和治疗的患者预后更好。在不伴脑炎的儿童癫痫中也见神经元抗体阳性的报道。文章旨在评估神经元抗体对儿童癫痫患者远期预后是否有影响。该前瞻性研究患者来自荷兰儿童癫痫研究(Dutch Study of Epilepsy,DSEC)的4个中心,于1988年-1992年期间招募患者(n=178),均未接受免疫治疗。以健康且年龄匹配的骨髓捐赠者作为正常对照(n=112)。所有受试者均使用标准方法,检测血清N-甲基-D-天冬氨酸受体(N-methyl-D-aspartate,NMDAR)、α氨基-3-羟基-5-甲基-4-异恶唑丙酸受体、富含亮氨酸胶质瘤失活1蛋白,接触蛋白相关蛋白2(Contactin associated protein like 2,CASPR2)、contactin-2、谷氨酸脱羧酶和电压门控钾通道(Voltage gated potassium channel,VGKC)-复合物抗体。均未使用脑脊液(Cerebrospinal fluid,CSF)样本检测。并将抗体检测结果与随访15年以上的临床资料进行相关性分析。17例患者(9.5%)神经元抗体检测为阳性,分别为VGKC复合物(n=3),NMDAR(n=7),CASPR2(n=4)和contactin-2(n=3),同时有3名(3/112,2.6%)健康对照者神经元抗体检测为阳性,VGKC复合物(n=1),NMDAR(n=2)(P=0.03)。虽然抗体滴度相对较低(细胞表面抗体≤1:100),但17例阳性样本中有8例(47%)可与活性海马神经元表面结合,提示具有潜在的致病性。在抗体阳性患者中更多见预先存在的认知障碍(9/17vs.33/161,P=0.01)。14例抗体阳性患者接受了规范的抗癫痫药物(AEDs)治疗。其中3例(17%)为耐药性癫痫,但与161例抗体阴性的患者中16例为耐药性癫痫(16人,10%)相比,不存在统计学差异。在6和/或12个月有随访样本的96例患者中,7例之前抗体阳性患者中6例抗体转阴,相反,另有7例患者在随访时第一次出现了抗体阳性。在9.5%的儿童新发癫痫患者中发现低水平的神经元抗体阳性,虽然抗体不一定会持续存在,但在随访中可见神经元抗体由阴性转为阳性,这表明抗体可能是由于神经元的损伤或炎症的继发反应所产生的。此外,由于抗体阳性的儿童癫痫患者对规范AEDs的反应和远期预后与抗体阴性患者没有差异,提示在儿童癫痫中常规进行神经元抗体检测意义不大。抗体阳性组中预先存在的认知障碍的发生率较高,17例患者中7例患者CASPR2和contactin-2抗体阳性,以及17例血清样品中8例与活性海马神经元的结合表明,即使是继发反应,神经元抗体也可能参与到儿童癫痫的共病发生中。 | Sukhvir Wright Ada T Geerts Cornelia Maria Jol-van der Zijde 熊维希 慕洁 | 2017 | 癫痫杂志2017，0，4： | 3 |
| 5 | Racial differences in effectiveness of α-fetoprotein for diagnosis of hepatocellular carcinoma in hepatitis C virus cirrhosis显示文摘 | Mindie H Nguyen Ruel T Garcia Peter W Simpson Teresa L Wright Emmet B Keeffe | 2002 | Hepatology2002，，2： | 2 |
| 6 | Paleoredox variations in ancient oceans recorded by rare earth elements in fossil apatite显示文摘 | Wright J Schrader H Holser W T | 1987 | Geochim Cosmochim Acta1987，51，： | 2 |
| 7 | Successful orthotopic liver transplanation forl amivudine-associated YMDD mutant hepatitis B virus显示文摘 | SAAB S KIM M WRIGHT T L | 2000 | Gastroenterology2000，119，5： | 2 |
| 8 | Rotating stall caused by pressure surface flow separation on centrifugal fan blades 显示文摘 | MADHAVAN S WRIGHT T | 1985 | ASME Journal of Engineering for Gas Turbines and Power1985，107，： | 2 |
| 9 | The experimental behavior of double skin composite elements 显示文摘 | WRIGHT H ODUYEMI T EVANS H R | 1991 | Journal of Constructional Steel Research1991，，19： | 1 |
| 10 | Novel 1xN and NxN Integrated Optical Switches Using Self-lmaging Multimode GaAs/Al-GaAs Waveguides显示文摘 | Jenkins R M Heaton J M Wright D R Parker J T Birbeck J C H Smith G W Hilton K P | 1994 | Appl Phys Lett 71994，64，： | 1 |
| 11 | Sub-Acute ruminal acidosis (SARA)in dairy cows显示文摘 | Wright T | 2003 | Ministry of Agriculture Food and Rural Affairs Dairy Sci2003，，85： | 1 |
| 12 | The relationship between HR practices and firm performance : Examining causal order 显示文摘 | Wright P M Gardner T M Moynihan L M | 2005 | Personnel Psychology2005，58，2： | 1 |
| 13 | Gradient projection for sparse reconstruction: applica- tion to compressed sensing and other inverse problems 显示文摘 | Figueiredo M A T Nowak R D Wright S J | 2007 | Selected Topics in Signal Processing2007，1，4： | 1 |
| 14 | The experimental behaviour of double skin composite elements显示文摘 | WRIGHT H D ODUYEMI T O S EVANS H R | 1991 | Journal of Constructional Steel Research1991，19，2： | 1 |
| 15 | The design of double skin composite elements 显示文摘 | Wright H D Oduyemi T O S Evans H R | 1991 | Journal of Constructional Steel Research1991，19，2： | 1 |
| 16 | (+)Abscisic acid, the growth inhibitor induced in detached leaves by a period of wilting显示文摘 | Wright S T C Hiron R W P | 1969 | Natrue1969，224，： | 1 |
| 17 | Expression cloning and cDNA sequenceing of the Na+/glucose cotransporter显示文摘 | Hediger M A Coady M J Ikeda T D Wright E M | 1987 | Nature1987，330，： | 1 |
| 18 | Preadipocyte recruitment in stromal vascular cultures after depletion of committed preadipocytes by immunocytotoxicity显示文摘 | YU Z K WRIGHT J T HAUSMAN G J | 1997 | Obesity Res1997，5，1： | 1 |
| 19 | Molecular-marker-facilitated investigation if quantitative trait loci in maize 4显示文摘 | Edwards M D Helentjaris T Wright S | 1992 | Theor Appl Genet1992，83，： | 1 |
| 20 | A multicenter United stales-Canadian trial to assess lamivudine monotherapy hefor and after liver transplantation for ehronie hepatitis B 显示文摘 | Perrillo RP wright T Rakela J | 2001 | Hepatology2001，33，2： | 1 |
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