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| 1 | Near-infrared fluorescence guided esophageal reconstructive surgery: A systematic review显示文摘BACKGROUND After an esophagectomy, the stomach is most commonly used to restore continuity of the upper gastrointestinal tract. These esophago-gastric anastomoses are prone to serious complications such as leakage associated with high morbidity and mortality. Graft perfusion is considered to be an important predictor for anastomotic integrity. Based on the current literature we believe Indocyanine green fluorescence angiography(ICGA) is an easy assessment tool for gastric tube(GT) perfusion, and it might predict anastomotic leakage(AL).AIM To evaluate feasibility and effectiveness of ICGA in GT perfusion assessment and as a predictor of AL.METHODS This study was designed according to the PRISMA guidelines and registered in the PROSPERO database. PubMed and EMBASE were independently searched by 2 reviewers for studies presenting data on intraoperative ICGA GT perfusion assessment during esophago-gastric reconstruction after esophagectomy.Relevant outcomes such as feasibility, complications, intraoperative surgical changes based on ICGA findings, quantification attempts, anatomical data and the impact of ICGA on postoperative anastomotic complications, were collected by 2 independent researchers. The quality of the included articles was assessed based on the Methodological Index for Non-Randomized Studies. The 19 included studies presented data on 1192 esophagectomy patients, in 758 patients ICGA was used perioperative to guide esophageal reconstruction.RESULTS The 19 included studies for qualitative analyses all described ICGA as a safe and easy method to evaluate gastric graft perfusion. AL occurred in 13.8% of the entire cohort, 10% in the ICG guided group and 20.6% in the control group(P <0.001). When poorly perfused cases are excluded from the analyses, the difference in AL was even larger(AL well-perfused group 6.3% vs control group 20.5%, P <0.001). The AL rate in the group with an altered surgical plan based on the ICG image was 6.5%, similar to the well perfused group(6.3%) and significantly less than the poorly perfused group(47.8%)(P < 0.001), suggesting that the technique is able to identify and alter a potential bad outcome.CONCLUSION ICGA is a safe, feasible and promising method for perfusion assessment. The lower AL rate in the well perfused group suggest that a good fluorescent signal predicts a good outcome. | Elke Van Daele Yves Van Nieuwenhove Wim Ceelen Christian Vanhove Bart P Braeckman Anne Hoorens Jurgen Van Limmen Oswald Varin Dirk Van de Putte Wouter Willaert Piet Pattyn | 2019 | World Journal of Gastrointestinal Oncology2019，11，3： | 3 |
| 2 | Flexible fabrication of microlenses in polymer layers with exeimer laser ablation显示文摘 | NAESSENS K OTTEVAERE H van DAELE P | 2003 | Appl Sur Sci2003，208，15： | 1 |
| 3 | Enhancement of 2,4-dichlorophenoxyacetic acid (2,4-D) degradation in soil by dissemination of catabolic plasmids 显示文摘 | Top E M Van Daele P De Saeyer N | 1998 | J Gen Mol Microbiol1998，73，： | 1 |
| 4 | Structural identifi- ability of biokinetic models of activated sludge respiration 显示文摘 | Dochain D Vanrolleghem P A Van Daele M | 1995 | Wa- ter Research1995，，29： | 1 |
| 5 | Polymorphisms in the lectin pathway genes as a possible cause of early chronic Pseudomonas aeruginosa colo- nization in cystic fibrosis patients 显示文摘 | Haerynck F Van Steen K Cattaert T Loeys B Van Daele S Schelstraete P | 2012 | Hum Immunol2012，3，11： | 1 |
| 6 | Long-term follow-up of re- sidual disease in acute lymphoblastic leukemia patients in complete remission using clonogeneic IgH probes and the polymerase chain reaetion显示文摘 | Nizet Y Van Daele S Lewalle P | 1993 | Blood1993，82，5： | 1 |
| 7 | The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound 显示文摘 | Briejers M R Bosmans J P Van Daele P | 2001 | Eur J Pharmacol2001，423，1： | 1 |
| 8 | Comparison of selenite and selenate apparent absorption and retention in in fants using stable isotope methodology 显示文摘 | Van Dael P Davidsson L Ziegler E E | 2002 | Pediat Res2002，51，： | 1 |
| 9 | Synthetics analgesics: N-( 1--4-substituted 4-piperidinyl) N2arylalkanamides显示文摘 | Van Daele P G H De Bruyn M F L Boey J M | 1976 | Arzneim-Forsch(Drug Res)1976，26，8： | 1 |
| 10 | Comparison of selenite and selenate apparent absorption and retention in infants using stableisotope methodology 显示文摘 | Van Dael P Davidsson L Ziegler E E | 2002 | Pediat Res2002，51，： | 1 |
| 11 | Bone mineral density in non insulin dependent diabetes mellitus显示文摘 | Van Daele P L R D Burger H | 1995 | Ann Intern Med1995，122，： | 1 |
| 12 | Long-term follow-up of residual disease in acute lymphoblastic leukemia patients in complete remission using clonogeneic IgH probes and the polymerase chain reaction显示文摘 | Nizet Y Van Daele S Lewalle P | 1993 | Blood1993，82，5： | 1 |
| 13 | Pulmonary function and maximal transrepiratory pressures in ankylonsing spondylitis显示文摘 | Vanderschueren D Decramer M Van Den Daele P | 1989 | Ann Rheum Dis1989，48，8： | 1 |
| 14 | Long-term follow-up of residual disease in acute lymphoblastic leukemia patients in complete remission using clonogeneic IgH probes and the polymerase chain reaction显示文摘 | Nizet Y Van Daele S Lewalle P | 1993 | Blood1993，82，5： | 1 |
| 15 | Practical identifiability of a biokinetic model of activated sludge respiration 显示文摘 | VANROLLEGHEM P A VAN DAELE M DOCHAIN D | 1995 | Wat Res1995，29，： | 1 |
| 16 | Bone density in non-insulin-dependent diabetes mellitus the Rotterdam Study显示文摘 | VAN DAELE P L STOLK R P BURGER H | 1995 | Ann Intern Med1995，122，6： | 1 |
| 17 | Pulmonary function and maximal transrepiratory pressures in ankylonsing spondylitis显示文摘 | Vanderschueren D Decramer M Van Den Daele P | 1989 | Ann Rheum Dis1989，48，8： | 1 |
| 18 | Recycling of guided mode light emission in planar mierocavity light emitting diodes显示文摘 | De Neve H Van Daele J B P Demeester P | 1997 | Applied Physics Letters1997，70，7： | 1 |
| 19 | Structural identi- fiability of bioklnetie models of activated sludge respiration 显示文摘 | Dochain D Vanrolleghem P A Van Daele M | 1995 | Water Research1995，29，： | 1 |
| 20 | Host nutritional selenium status as a driving force for influenza virus mutations显示文摘 | Nelson HK Shi Q Van Dael P | 2001 | FASEB J2001，15，10： | 1 |
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