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| 1 | Management of syndesmotic injuries:What is the evidence?显示文摘Ankle fractures are accompanied by a syndesmotic injury in about 10% of operatively treated ankle fractures. Usually, the total rupture of the syndesmotic ligaments with an external rotation force is associated with a Weber type B or C fracture or a Maisonneuve fracture. The clinical assessment should consist of a comprehensive history including mechanism of injury followed by a specific physical examination. Radiographs, and if in doubt magnetic resonance imaging, are needed to ascertain the syndesmotic injury. In the case of operative treatment the method of fixation, the height and number of screws and the need for hardware removal are still under discussion. Furthermore, intraoperative assessment of the accuracy of reduction of the fibula in the incisura using fluoroscopy is difficult. A possible solution might be the assessment with intraoperative three-dimensional imaging. The aim of this article is to provide a current concepts review of the clinical presentation, diagnosis and treatment of syndesmotic injuries. | Marc Schnetzke Sven Y Vetter Nils Beisemann Benedict Swartman Paul A Grützner Jochen Franke | 2016 | World Journal of Orthopedics2016，7，11： | 4 |
| 2 | The effect of human proinsulin C-peptide on erythrocyte deformability in patients with type 1 diabetes mellitus显示文摘 | Kunt T Schneider S Pfützner A | 1999 | Diabetologia1999，42，4： | 1 |
| 3 | Efficacy and safety of rivaroxaban or fondaparinux thromboprophylaxis in major orthopedic surgery: findings from the ORTHO‐TEP registry显示文摘 | J. BEYER‐WESTENDORF J. LüTZNER L. DONATH O. C. RADKE E. KUHLISCH A. HARTMANN N. WEISS S. WERTH | 2012 | Journal of Thrombosis and Haemostasis2012，，10： | 1 |
| 4 | Initial combination ther-apy with saxagliptin and metformin provides sustained glycaemiccontrol and is well tolerated for up to 76 weeks显示文摘 | Pfützner A Paz-Pacheco E Allen E | 2011 | Diabetol ObesMetab2011，13，6： | 1 |
| 5 | Improvement of cardiovascular risk markers by pioglitazone is independent from glycemic control:results from the pioneer study显示文摘 | Pfützner A Marx N Lübben G | | Journal of the American College of Cardiology0，，： | 1 |
| 6 | GSH attenuates organ injury and improves function after transplantation of fatty livers显示文摘 | Pratschke S Angele MK Grützner U | 2010 | Eur Surg Res2010，45，1： | 1 |
| 7 | Interuationale und national Entwicklungstendenzen anf der Grundlage der Ergebnisse der olymisch en sommerspiele und der olypiazklusanalyse 2004 mit folgerungen für den olympiazyklus bis 2008显示文摘 | PF(U)TZNER A REI M | | 0，，01： | 1 |
| 8 | TRACP 5b and CTX as osteological markers of delayed fracture healing显示文摘 | A. Moghaddam U. Müller H.J. Roth A. Wentzensen P.A. Grützner G. Zimmermann | 2010 | Injury2010，，： | 1 |
| 9 | Induction of cytotoxicity against autologous tumour cells by interleukin-12:evidence for intrinsic anti-tumor immune capacity in curatively resected gastrointestinal tumour patients显示文摘 | Michael Str?hlein Klaus-Uwe Grützner Friedrich-Wilhelm Schildberg Markus Heiss | 2002 | Cancer Immunology Immunotherapy2002，，9： | 1 |
| 10 | A PCR scheme for differentiation of organisms belonging to the Mycoplasma mycoides cluster显示文摘 | H. Hotzel K. Sachse H. Pfützner | 1996 | Veterinary Microbiology1996，，1： | 1 |
| 11 | Tailoring of novolak resins for photoresist applications using a two step synthesis procedure显示文摘 | Bahr G Westerwelle U Grǘtzner G | 1997 | SPIE Proceedings1997，，3049： | 1 |
| 12 | Clinical and laboratory evaluation of specific chemiluminescence assays for intact and total proinsulin显示文摘 | Pfützner A Kunt T Langenfeld M | 2003 | Clin Chem Lab Med2003，41，9： | 1 |
| 13 | 1 Antiinflammatoryeffects of pioglitazone and/or simvastatin in high cardiovascularrisk patients with elevated high sensitivity C -reactive protein:the PIOSTAT study显示文摘 | Hanefeld M Marx N Pt ti tzner A et a | 2007 | JAm CollCardio2007，49，3： | 1 |
| 14 | Heine oxygenase-1 protects human hepatocytes in vitro against warm and cold hypoxia显示文摘 | Tzner E Liu L Shimada M | 2004 | J Hepatol2004，41，5： | 1 |
| 15 | Influence of Glucose Control and Improvement of Insulin Resistance on Microvascular Blood Flow and Endothelial Function in Patients with Diabetes Mellitus Type 2显示文摘 | THOMASFORST GEORGLüBBEN CLOTHILDEHOHBERG PETERKANN CHRISTIANSACHARA VOLKERGOTTSCHALL CHRISTIANEFRIEDRICH REINERRO?KOPF ANDREASPFüTZNER | 2010 | Microcirculation2010，，7： | 1 |
| 16 | Repeatability of measurements of the rectal temperature and comparison of vaginal and rectal temperature in puerperal sows显示文摘 | Stiehler T Heuwieser W Pf(u)tzner A | 2013 | Tierarztl Prax Ausg G Grosstiere Nutztiere2013，41，4： | 1 |
| 17 | 3D printing of patient-specific implants for osteochondral defects: workflow for an MRI-guided zonal design显示文摘Magnetic resonance imaging(MRI)is a common clinical practice to visualize defects and to distinguish different tissue types and pathologies in the human body.So far,MRI data have not been used to model and generate a patient-specific design of multilayered tissue substitutes in the case of interfacial defects.For orthopedic cases that require highly individual surgical treatment,implant fabrication by additive manufacturing holds great potential.Extrusion-based techniques like 3D plot-ting allow the spatially defined application of several materials,as well as implementation of bioprinting strategies.With the example of a typical multi-zonal osteochondral defect in an osteochondritis dissecans(OCD)patient,this study aimed to close the technological gap between MRI analysis and the additive manufacturing process of an implant based on dif-ferent biomaterial inks.A workflow was developed which covers the processing steps of MRI-based defect identification,segmentation,modeling,implant design adjustment,and implant generation.A model implant was fabricated based on two biomaterial inks with clinically relevant properties that would allow for bioprinting,the direct embedding of a patient’s own cells in the printing process.As demonstrated by the geometric compatibility of the designed and fabricated model implant in a stereolithography(SLA)model of lesioned femoral condyles,a novel versatile CAD/CAM workflow was successfully established that opens up new perspectives for the treatment of multi-zonal(osteochondral)defects. | David Kilian Philipp Sembdner Henriette Bretschneider Tilman Ahlfeld Lydia Mika Jörg Lützner Stefan Holtzhausen Anja Lode Ralph Stelzer Michael Gelinsky | 2021 | Bio-Design and Manufacturing2021，4，4： | 1 |
| 18 | Computer-assisted and conventional total knee replacement:A comparative,prospective,randomized study with radiological and CT evaluation显示文摘 | Lützner J Krummenauer F Wolf C | 2008 | J Bone Joint Surg Br2008，90，8： | 1 |
| 19 | High-sensitivity C-reactive protein as cardiovascular risk marker in patients with diabetes mellitus显示文摘 | Pfützner A Forst T | 2006 | Diabetes Technol Ther2006，8，1： | 1 |
| 20 | Saxagliptin given in combination with metformin as initial therapy improves glycaemic control in patients with type 2 diabetes compared with either monotherapy:a randomized controlled trial显示文摘 | Jadzinsky M Pfützner A Paz-Pacheco E | 2009 | Diabetes Obes Metab2009，11，6： | 1 |
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