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| 1 | 北京地区医务人员SARS感染的分析显示文摘目的 探讨医务人员SARS医院感染的危险因素。方法 对北京地区 2 0 0 3年 3月 2 0日~ 2 0 0 3年 5月 31日 6 6 6所医院进行医务人员SARS感染调查。结果 医务人员SARS感染的发病期较社会人群前移 ,综合门 (急 )诊医务人员SARS感染发病率占医务人员感染构成比 71 34% ,其中护士占 4 8 81% ,医生占 35 4 9% ;年龄 <4 0岁占 83 5 8% ;医务人员感染暴发为三级医院为主 6 9 2 8%。结论 由于信息封闭、指导诊断失误和控制措施不利导致SARS在北京地区暴发 ,医务人员是首批受感染者同时也是医院感染的传播链 ;必须在人类与疾病的斗争中加强医务人员的职业防护与保健。 | 魏华 李素英 刘坤 吕超英 高居中 北京市SARS医疗救治指挥中心医院感染控制专家组 | 2003 | 中华医院感染学杂志2003，13，8： | 77 |
| 2 | 现代集装箱港口体系演进理论与实证显示文摘集装箱技术的传播深刻影响了港口体系的发展,集装箱港口体系的理论模型重点解析该技术对港口体系空间时序过程的影响机制。基于相关研究进展的回顾与评述,根据港口发展的新现象与新机制,综合Hayuth和Notterboom的理论模型,介绍了集装箱港口体系的最新理论,将其分为前集装箱化、技术试验、巩固集中化、枢纽港中心化、扩散化与离岸枢纽、港口区域化等六个时序阶段,对各阶段的发展特征进行了刻画和解析,并从枢纽港本地约束、集装箱航运模式、物流资源整合、内陆配送网络与干港、政府宏观调控和港口建设市场化等角度揭示了扩散化与离岸枢纽、港口区域化两个最新阶段的发展机制。并以长江三角洲作为案例进行实证,详细解析了长江三角洲集装箱港口体系的演化过程,重点是发展变化与内在机理,验证了本文的集装箱港口体系模型,探讨了该区域可能面临的发展趋势。 | 王成金 César Ducruet | 2011 | 地理研究2011，30，3： | 41 |
| 3 | Epidemiology, demographic characteristics and prognostic predictors of ulcerative colitis显示文摘Ulcerative colitis(UC)is a chronic disease characterized by diffuse inflammation of the mucosa of the colon and rectum.The hallmark clinical symptom of UC is bloody diarrhea.The clinical course is marked by exacerbations and remissions,which may occur spontaneously or in response to treatment changes or intercurrent illnesses.UC is most commonly diagnosed in late adolescence or early adulthood,but it can occur at any age.The incidence of UC has increased worldwide over recent decades,especially in developing nations.In contrast,during this period,therapeutic advances have improved the life expectancy of patients,and there has been a decrease in the mortality rate over time.It is important to emphasize that there is considerable variability in the phenotypic presentation of UC.Within this context,certain clinical and demographic characteristics are useful in identifying patients who tend to have more severe evolution of the disease and a poor prognosis.In this group of patients,better clinical surveillance and more intensive therapy may change the natural course of the disease.The aim of this article was to review the epidemiology and demographic characteristics of UC and the factors that may be associated with its clinical prognosis. | Bruno César da Silva Andre Castro Lyra Raquel Rocha Genoile Oliveira Santana | 2014 | World Journal of Gastroenterology2014，20，28： | 48 |
| 4 | 传染性非典型肺炎的血清学诊断研究显示文摘目的 评估传染性非典型肺炎 (世界卫生组织又称严重急性呼吸综合征 ,SARS)血清病毒特异性抗体检测在SARS诊断中的实用价值 ,了解免疫荧光抗体法 (IFA )和酶联免疫吸附法(ELISA)对SARS病毒特异性抗体检测结果的一致性程度。方法 用IFA和ELISA检测 2 6 7例不同病程SARS患者和 132例对照组血清SARS病毒特异性抗体 ,以敏感度、特异度、阳性预测值(PPV)、阴性预测值 (NPV)和准确度评价其诊断价值 ,并以Kappa值评价两种检测方法结果的一致性。结果以IFA检测的血清特异性IgM类和IgG类抗体阳性率在病程第 11天明显增高 ,病程≥ 11天者 ,IgM类抗体诊断SARS的敏感度为 6 5 6 % ,特异度 10 0 0 % ,PPV 10 0 0 % ,NPV 71 0 % ,准确度 81 3% ;IgG类抗体则分别为敏感度 91 1% ,特异度 97 0 % ,PPV 97 3% ,NPV 90 1% ,准确度93 8%。以ELISA方法所测结果与IFA结果相仿。对IFA和ELISA法检测的一致性检验示Kappa值分别为 0 6 4 0和 0 779。结论 血清病毒特异性抗体在SARS发病 10天以上者阳性率高 ,抗体检测有助于确立发病 10天以上SARS的血清学诊断。IFA和ELISA检测SARS病毒抗体的一致性较好。 | 国家SARS防治紧急科技行动北京组 | 2003 | 中华结核和呼吸杂志2003，26，6： | 46 |
| 5 | Sr-Nd isotopic compositions of the Changjiang sediments: Implications for tracing sediment sources显示文摘The suspended particulate and fine-grained floodplain sediments were collected from the main stream and tributaries of the Changjiang River for Sr-Nd isotopic measurements. The εNd(0) values gradually decrease downstream from -10.8 on average in the upper reaches to -12.3 in the lower reaches, whereas the 87Sr/86Sr ratios increase correspondingly, averaging 0.721899 and 0.725826 respectively in the upper and middle-lower reaches. The compositional variations primarily reflect the complex con- trols of provenance rocks, chemical weathering, and sediment characters between different catchments, among which the abnormal Sr-Nd isotopic compositions of the Yalong, Fujiang, Tuojiang and Yuanjiang rivers indicate the sediment provenance contributions from the Emeishan Basalt in the upper reaches and the old metamorphic and siliceous rocks in the middle-lower reaches. The Sr-Nd isotopic ratios of the Changjiang sediments can better reflect the average composition of weathered continental crust compared to other major rivers in the world because of the unique source rock types in the Changjiang drainage basin. The recognition of the Sr-Nd isotopic systematics of the Changjiang sediments will contribute to our understanding of the Changjiang evolution history and continental weathering processes during the Cenozoic, and also to reconstructing the paleoenvironmental changes in East China and the marginal seas. | YANG ShouYe1?, JIANG ShaoYong2, LING HongFei2, XIA XiaoPing3, SUN Min3 & WANG DeJie4 1 State Key Laboratory of Marine Geology, Tongji University, Shanghai 200092, China 2 State Key Laboratory for Mineral Deposit Research, Nanjing University, Nanjing 210093, China 3 Departmen of Earth Sciences, The University of Hong Kong, Hong Kong SAR, China 4 Development Research Center, China Geological Survey, Beijing 100083, China | 2007 | Science China Earth Sciences2007，50，10： | 32 |
| 6 | Stability of SARS Coronavirus in Human Specimens and Environment and Its Sensitivity to Heating and UV Irradiation显示文摘The causal agent for SARS is considered as a novel coronavirus that has never been described both in human and animals previously. The stability of SARS coronavirus in human specimens and in environments was studied. Methods Using a SARS coronavirus strain CoV-P9,which was isolated from pharyngeal swab of a probable SARS case in Beijing, its stability in mimic human specimens and in mimic environment including surfaces of commonly used materials or in household conditions, as well as its resistances to temperature and UV irradiation were analyzed. A total of 106 TCID50 viruses were placed in each tested condition, and changes of the viral infectivity in samples after treatments were measured by evaluating cytopathic effect (CPE) in cell line Vero-E6 at 48 h after infectionn. Results The results showed that SARS coronavirus in the testing condition could survive in serum, 1:20 diluted sputum and feces for at least 96 h, whereas it could remain alive in urine for at least 72 h with a low level of infectivity. The survival abilities on the surfaces of eight different materials and in water were quite comparable, revealing reduction of infectivity after 72 to 96 h exposure. Viruses stayed stable at 4℃, at room temperature (20℃) and at 37℃ for at least 2 h without remarkable change in the infectious ability in cells, but were convened to be non-infectious after 90-, 60- and 30-min exposure at 56℃, at 67℃ and at 75℃, respectively. Irradiation of UV for 60 min on the virus in culture medium resulted in the destruction of viral infectivity at an undetectable level. Conclusion The survival ability of SARS coronavirus in human specimens and in environments seems to be relatively strong. Heating and UV irradiation can efficiently eliminate the viral infectivity. | SHU-MING DUAN, XIN-SHENG ZHAO, RUI-FU WEN, JING-JING HUANG, GUO-HUA PI, SU-XIANG ZHANG, JUN HAN, SHENG-LI BI, LI RUAN, XIAO-PING DONGAND SARS RESEARCH TEAMInstitute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention,Ying-Xin Rd. 100, Beijing 100052, China | 2003 | Biomedical and Environmental Sciences2003，16，3： | 29 |
| 7 | SARS对中国经济的影响与对策显示文摘传染性非典型性肺炎的肆虐 ,在给人民生命健康造成危害的同时 ,也对我国的政治、经济、法律、社会等方面产生了影响。为了及时研究这种影响 ,提出应对措施 ,为党和政府决策提供咨询服务 ,南开大学组成以副校长逄锦聚教授为负责人的课题组 ,拨出专项经费 ,集中经济学、管理学、政治学、社会学、法学等学科的几十位教师和研究生 ,于 2 0 0 3年 4月底展开了 SA RS对中国政治、经济、法律、社会的影响与对策的研究。至 5月下旬 ,课题组完成了相应的四个主报告以及 SARS对我国宏观经济、物流产业、对外贸易、股票市场、保险业、引进外资和旅游业的影响与对策等二十余份分报告。这些成果分别报送了中央和天津市领导部门 ,有的内容以内部文稿的形式报中央领导同志参阅 ,有的被《人民日报》等报刊发表。在上述研究的基础上 ,本刊组织了这期笔谈。 | 南开大学SARS对经济影响研究课题组 | 2003 | 南开学报(哲学社会科学版)2003，，4： | 23 |
| 8 | Feasibility and safety of autologous bone marrow mononuclear cell transplantation in patients with advanced chronic liver disease显示文摘AIM: To evaluate the safety and feasibility of bone marrow cell (BMC) transplantation in patients with chronic liver disease on the waiting list for liver transplantation. METHODS: Ten patients (eight males) with chronic liver disease were enrolled to receive infusion of autologous bone marrow-derived cells. Seven patients were classified as Child-Pugh B and three as Child-Pugh C. Baseline assessment included complete clinical and laboratory evaluation and abdominal MRI. Approximately 50 ml of bone marrow aspirate was prepared by centrifugation in a ficoll-hypaque gradient. At least of 100 millions of mononuclear-enriched BMCs were infused into the hepatic artery using the routine technique for arterial chemoembolization for liver tumors. Patients were followed up for adverse events up to 4 mo. RESULTS: The median age of the patients was 52 years (range 24-70 years). All patients were discharged 48 h after BMC infusion. Two patients complained ofmild pain at the bone marrow needle puncture site. No other complications or specific side effects related to the procedure were observed. Bilirubin levels were lower at 1 (2.19 ± 0.9) and 4 mo (2.10 ± 1.0) after cell transplantation that baseline levels (2.78 ± 1.2). Albumin levels 4 mo after BMC infusion (3.73 ± 0.5) were higher than baseline levels (3.47 ± 0.5). International normalized ratio (INR) decreased from 1.48 (SD = 0.23) to 1.43 (SD = 0.23) one month after cell transplantation. CONCLUSION: BMC infusion into hepatic artery of patients with advanced chronic liver disease is safe and feasible. In addition, a decrease in mean serum bilirubin and INR levels and an increase in albumin levels are observed. Our data warrant further studies in order to evaluate the effect of BMC transplantation in patients with advanced chronic liver disease. | Andre Castro lyra Milena Botelho Pereira Soares luiz Flavio Maia da Silva Marcos Fraga Fortes André Goyanna Pinheiro Silva Augusto César de Andrade Mota Sheilla A Oliveira Eduardo lorens Braga Wilson Andrade de Carvalho Bernd Genser Ricardo Ribeiro dos Santos luiz Guilherme Costa lyra | 2007 | World Journal of Gastroenterology2007，13，7： | 21 |
| 9 | 严重急性呼吸综合征患者肾上腺糖皮质激素使用的多因素COX回归分析显示文摘目的 探讨SARS治疗中糖皮质激素 (GCS)的疗效及使用方法。方法 收集北京市SARS病历资料 ,对全部病例进行分析诊断 ,建立数据库 ,输入每日临床症状、体格检查及辅助检查。共 12 91例临床诊断病例资料完整 ,作为研究对象 ,分别进行单因素分析及COX多因素回归分析。GCS均换算为甲泼尼龙的剂量 (mg/d)。结果 共 10 84例使用了GCS治疗 ,占总例数的 83 96 % ,未使用GCS者为 2 0 7例。两组年龄 (t =- 1 0 8,P >0 0 5 )、住院距离发病的时间差异均无显著意义(P >0 0 5 )。多因素COX回归分析显示应用GCS组较未用组的病死危险性略高 ,RR为 1 334(95 %可信区间 :0 5 88~ 3 0 2 6 )。其中有基础病使用GCS者RR为 2 0 86 (95 %可信区间 :0 6 94~ 6 2 6 7) ,无基础疾病者为 0 5 36 (95 %可信区间 0 14 6~ 1 970 ) ,P >0 0 5。无基础病患者 ,起始剂量、最大剂量、平均剂量、累积剂量与病死率均呈现“J”型关系 ,过低和过高均增加病死相对危险度 ,中间剂量病死危险略有降低 ,但差异均无显著意义 (P >0 0 5 )。病死相对危险度最低的起始剂量、最大剂量、平均剂量、累积剂量依次为 80~ 16 0mg/d、80~ 16 0mg/d、<80mg/d、10 0 0~ 30 0 0mg。无基础病发病14d以内开始使用GCS者病死RR均小于 1,在 15d后使? | 王广发 李楠 武阳丰 谢高强 林江涛 黄慈波 夏国光 韩德民 北京市SARS医疗救治指挥中心科技攻关组 | 2004 | 中华医学杂志2004，84，13： | 19 |
| 10 | 突发公共卫生事件的应急管理美国与中国的案例显示文摘随着全球一体化和信息多元化的发展,日益突出的突发公共卫生事件已经成为任何国家或政府都必须认真对待的重大问题。近期发生的SARS事件,不仅是一次恶性疫病的传播,更已发展成为开放和信息多元化背景下的全球性公共事务危机,这不仅对我国的政府治理结构和治理能力提出重大挑战,而且也对全球协同应对危机的能力构成了严峻考验。 | 清华大学危机管理研究中心SARS危机应急课题组 | 2003 | 世界知识2003，，10： | 17 |
| 11 | Diagnosis of pancreatic tumors by endoscopic ultrasound-guided fine-needle aspiration显示文摘AIM: To evaluate the diagnostic accuracy of endoscopic ultrasound-guided fi ne-needle aspiration (EUS-FNA) for pancreatic solid tumors larger or smaller than 3 cm, and cystic lesions. METHODS: From January/1997 to December/2006, 611 patients with pancreatic tumors were subjected to EUS-FNA. The fi nal diagnosis was obtained either by surgery (356 cases) or after a mean clinical follow-up of 11.8 mo in the remaining patients. RESULTS: There were 405 solid tumors, 189 cystic lesions and 17 mixed. Pancreatic specimens for cytological assessment were successfully obtained by EUS-FNA in 595 (97.4/) cases. There were 352 (57.6/) malignancies and 259 (42.4/) benign tumors. Among the malignancies, pancreatic adenocarcinomas accounted for 67/ of the lesions. Overall, the sensitivity, specifi city, positive and negative predictive values, and accuracy of EUS-FNA were, respectively, 78.4/, 99.2/, 99.3/, 77.2/ and 87.2/. Specif ically for solid tumors, the same parameters for neoplasms larger and smaller than 3 cm were, respectively, 78.8/ vs 82.4/, 100/ vs 98.4/, 100/ vs 99/, 54.8/ vs 74.1/ and 83.1/ vs 87.8/. For cystic lesions, the values were, respectively, 72.2/, 99.3/, 97.5/, 91/ and 92.2/. CONCLUSION: EUS-FNA can be used to sample pancreatic tumors in most patients. Even though the negative predictive value is inadequate for large solid tumors, the results are rather good for small solid tumors, especially concerning the sensitivity, negative predictive value and diagnostic accuracy. Among all pancreatic lesions, EUS-FNA for cystic lesions canreveal the best negative predictive value and diagnostic accuracy, both higher than 90/. | José Celso Ardengh César Vivian Lopes Luiz Felipe Pereira de Lima Juliano Rodrigues de Oliveira Filadélfi o Venco Giulio Cesare Santo José Luiz Pimenta Módena | 2007 | World Journal of Gastroenterology2007，13，22： | 17 |
| 12 | SARS患者T细胞和免疫球蛋白动态变化的研究显示文摘目的 研究传染性非典型肺炎 (SARS)患者免疫功能及其在病程中的变化。方法 用流式细胞仪测定 12 4例不同病程SARS患者外周血CD3+ 、CD4 + 和CD8+ T细胞计数 ,同时测定免疫球蛋白 ,另设 5 1例获得性免疫缺陷综合征 (AIDS)患者和 5 7名健康人为对照组 ;对SARS患者进行病程分组 ,比较不同病程免疫功能的变化。结果 SARS组CD3+ [(5 89± 4 35 )× 10 6/L]、CD4 + [(316± 2 6 7)× 10 6/L]和CD8+ T细胞 [(2 15± 16 5 )× 10 6/L]均显著低于健康对照组 [(116 3± 32 4 )× 10 6/L、(6 4 1±186 )× 10 6/L和 (4 0 5± 14 6 )× 10 6/L],但CD4 + T细胞高于AIDS组 [(15 3± 10 5 )× 10 6/L],CD3+ 和CD8+T细胞则低于AIDS组 [(112 2± 5 72 )× 10 6/L、(96 9± 5 4 6 )× 10 6/L](P值均 <0 0 1)。SARS组和AIDS组分别有 5 4例 (4 4 % )和 39例 (76 % )CD4 + T细胞 <2 0 0× 10 6/L。SARS患者外周血T细胞亚群计数在病程 10~ 12d达最低值。SARS组血清IgG(15 1g/L± 8 5g/L)和IgE(0 6g/L± 0 9g/L)水平高于健康对照组 (12 4g/L± 2 2g/L ,0 3g/L± 0 6g/L)。结论 SARS患者CD3+ 、CD4 + 及CD8+ T细胞均显著减少 ,病程 10~ 12d为最低值阶段。 | 国家SARS防治紧急科技行动北京组 | 2003 | 中华医学杂志2003，83，12： | 16 |
| 13 | 北京市SARS临床诊断病例住院费用及影响因素分析显示文摘目的 了解2003年北京市救治SARS患者的住院费用和影响住院费用的因素。方法统计北京市SARS临床诊断病例数据库中资料完整的1272例SARS患者住院人均费用和日均费用及其构成情况,并采用多因素线性回归来探索影响费用的因素。结果 北京市SARS患者的人均住院费用和日均住院费用分别为18 767.50元/人和632.02元/天。总费用构成中药物治疗花费占65.78%。经单因素分析、分层分析和多元线性回归分析表明:住院天数越长花费越大,病情越重花费越大,早期发病患者花费显著高于晚期发病患者,医务人员住院费用显著高于非医务人员,有基础病的患者平均花费显著高于无基础疾病的患者,公费医疗患者花费显著高于自费医疗患者,采用机械通气的患者花费显著高于未采用机械通气的患者。结论 SARS患者住院费用较高,影响SARS患者住院费用的因素有住院天数、病情、住院时期、职业、基础病及付费方式等。 | 肖峰 陈博文 武阳丰 王月香 韩德民 北京市SARS医疗救治指挥中心科技攻关组 | 2004 | 中华流行病学杂志2004，25，4： | 12 |
| 14 | Phase Ⅰ of cardiac rehabilitation:A new challenge for evidence based physiotherapy显示文摘Cardiac rehabilitation protocols applied during the inhospital phase(phaseⅠ)are subjective and their results are contested when evaluated considering what should be the three basic principles of exercise prescription:specificity,overload and reversibility.In this review,we focus on the problems associated with the models of exercise prescription applied at this early stage in-hospital and adopted today,especially the lack of clinical studies demonstrating its effectiveness.Moreover,we present the concept of'periodization'as a useful tool in the search for better results. | Rafael Michel de Macedo JoséRocha Faria-Neto Costantino Ortiz Costantini Dayane Casali Andrea Pires Muller Costantino Roberto Costantini Katherine Athayde Teixeira de Carvalho Luiz César Guarita-Souza | 2011 | World Journal of Cardiology2011，3，7： | 11 |
| 15 | Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for patients with previously untreated advanced oesophagogastric cancer (REAL3): a randomised, open-label phase 3 trial显示文摘 | Tom Waddell Ian Chau David Cunningham David Gonzalez Alicia Frances Clare Okines Andrew Wotherspoon Claire Saffery Gary Middleton Jonathan Wadsley David Ferry Wasat Mansoor Tom Crosby Fareeda Coxon David Smith Justin Waters Timothy Iveson Stephen Falk Sar | 2013 | Lancet Oncology2013，，6： | 10 |
| 16 | ^(40)Ar-^(39)Ar and U-Pb ages of metadiorite from the East Kunlun Orogenic Belt: Evidence for Early-Paleozoic magmatic zone and excess argon in amphibole minerals显示文摘Single-grain zircon U-Pb and amphibole 40Ar-39Ar dating have been conducted on a deformed and metamorphosed diorite in the East Kunlun Orogenic Belt, which intruded into the middle Proterozoic Kuhai Group exposed in the south of Xiangride region, Dulan County, NW Qinghai Province. The zircon gives a concordant U-Pb age of (446.5±9.1) Ma. The amphibole yields Ar plateau age of (488.0±1.2) Ma and an isochronal age of (488.9±5.6) Ma. Age results of both stepwise released Ar and conventional K-Ar analysis are remarkably higher than that of zircon U-Pb, suggesting that the amphibole contains excess argon and the amphibole plateau age cannot be taken as the timing of metamorphism or deformation. The zircon age is interpreted to be crystallization age of the diorite pluton, which suggests that an Early-Paleozoic magmatic zone indeed existed in the East Kunlun Orogenic Belt stretching along the region south to the Golmud, Normuhong and Xiangride. | CHEN Nengsong, SUN Min, ZHANG Kexin & ZHU YunhaiFaculty of Earth Sciences, China University of Geosciences, Wuhan 430074, China Department of Earth Sciences, The University of Hong Kong, Hong Kong SAR, China | 2001 | Chinese Science Bulletin2001，46，4： | 10 |
| 17 | Growth mechanism of octahedron-like BaMoO_4 microcrystals processed in microwave-hydrothermal:Experimental observations and computational modeling显示文摘Octahedron-like BaMoO4 microcrystals were synthesized by the co-precipitation method at room temperature and processed in microwave-hydrothermal at 413 K for different times (from 30 min to 5 h). These microcrystals were analyzed by X-ray diffraction (XRD),field-emission gun scanning electron microscopy (FEG-SEM) and transmission electron microscopy (TEM). XRD patterns showed that this material presents a tetragonal structure without the presence of deleterious phases. FEG-SEM and TEM micrographs revealed that the BaMoO4 microcrystals present an octahedron-like morphology with agglomerate nature and poly-disperse particle size distribution. These micrographs also indicated that the microcrystals grow along the [0 0 1] direction. The observed crystallographic planes in these structures were modeled computationally and a crystal growth model was proposed in order to explain the morphological changes as a function of processing time. | Laécio Santos Cavalcante Júlio César Sczancoski Rircado Luis Tranquilin José Arana Varela Elson Longo Marcelo Ornaghi Orlandi | 2009 | Particuology2009，7，5： | 9 |
| 18 | Port Integration in China: Temporal Pathways, Spatial Patterns and Dynamics显示文摘Over the past two decades, numerous ports located in China have participated in port integration strategies, thus influencing the entire port system. The current research is initiated in order to examine the nature of port integration in China, including associated temporal pathways, spatial patterns and dynamics. Results indicate that port integration in China has been characterized by a significant increase at the turn of the 21 st century, comprising thirteen distinguishable pathways typified by differing dynamics, particularly between the northern and southern ports. Pathways were found to include 44 seaports and river ports, chiefly concentrated in the Bohai Rim, Yangtze(Changjiang) River Delta, Beibu Gulf and the southeastern Fujian, thus representing significant spatial regions. Categorically larger seaports have become the primary beneficiaries of port integration. Integration cases were divided into four categories based upon quantified dynamic magnitude including the government-driven mode, market-driven mode, government/market-driven mode and strategic alliance, and into five further categories based upon spatial extent including port internal integration, jurisdictional port integration, port integration across neighbor region, regional port integration and hub-feeder port integration. Results suggest that several factors have effectively driven port integration in China, including legislative tools and spatial planning, optimization of shoreline resources and port functionality, and port competition with the same hinterland. | WANG Chengjin César DUCRUET WANG Wei | 2015 | Chinese Geographical Science2015，25，5： | 8 |
| 19 | 严重急性呼吸综合征54例临床分析显示文摘目的 :探讨当前流行的严重急性呼吸综合征 (SARS)的流行病学、临床表现、实验室检查、X线表现等特点及其治疗和预后。方法 :对我院2003年4月19日—5月31日收治的54例SARS患者的流行病学及临床资料进行分析。结果 :患病年龄为20~83岁 ,平均 (43.61±13.76)岁 ,男27例 ,女27例 ,潜伏期1~19d ,平均 (6.08±4.10)d ,主要临床表现有发热 (100 % ) ,憋气 (64.81% ) ,干咳 (51.85% ) ,发冷 (25.93% ) ,腹泻 (11.11 % )。外周血淋巴细胞降低占74 07% ,血清丙氨酸转氨酶升高29例 (53.70 % ) ,乳酸脱氢酶升高22例 (40.74 % ) ,全部患者X线片均有肺部病变。治疗以糖皮质激素为主 ,给氧、抗病毒、抗生素。本组治疗好转率为96 30%。结论 :SARS传染性强 ,以发热、咳嗽、胸片表现及外周血淋巴细胞降低为临床特点 ,可预防 。 | 天津市传染病医院SARS救治组 | 2003 | 天津医药2003，31，6： | 8 |
| 20 | Relative peripheral refraction across 4 meridians after orthokeratology and LASIK surgery显示文摘Background:To characterize the axial and off-axis refraction across four meridians of the retina in myopic eyes before and after Orthokeratology(OK)and LASIK surgery.Methods:Sixty right eyes with a spherical equivalent(M)between−0.75 to−5.25 D(cylinder<−1.00 D)underwent LASIK(n=26)or OK(n=34)to treat myopia.Axial and off-axis refraction were measured with an open-field autorefractometer before and after stabilized treatments.Off-axis measurements were obtained for the horizontal(35°nasal and temporal retina)and vertical(15°superior and inferior retina)meridians,and for two oblique directions(45–225°and 135–315°)up to 20°of eccentricity.The refractive profile was addressed as relative peripheral refractive error(RPRE).Results:OK and LASIK post-treatment results showed an increase of myopic relative refraction at several eccentric locations.At the four meridians evaluated,the M component of the pre-treatment RPRE values was not statistically different(p>0.05)from the post-treatment RPRE within 30°and 20°of the central visual field after LASIK and OK,respectively.These results demonstrated that the treatment zone warrants an optimal central field of vision.Conclusions:The present study gives an overview of RPRE after refractive corneal reshaping treatments(OK and LASIK)across vertical,horizontal and two oblique meridians together.This allows a 3D representation of RPRE at the retina and shows that the myopic shift induced by both treatments is more relevant in horizontal directions. | António Queirós Ana Amorim-de-Sousa Daniela Lopes-Ferreira César Villa-Collar Ángel Ramón Gutiérrez JoséManuel González-Méijome | 2018 | Eye and Vision2018，5，1： | 8 |
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