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| 1 | New advances in in-situ thermal desorption technology for contaminated soil显示文摘With the development of ecological civilization and economic construction,remediation of contaminated soils has caused more and more concern of scientists and engineers.Situ thermal desorption is a mature and effective technology which is especially suitable for the contaminated soil of relocated chemical plant[1,2],Compared with in-situ chemical oxidation and ectopic thermal desorption,the in-situ thermal desorption has stronger applicability and higher repair efficiency.The main applications of the in-situ thermal desorption technology are semi-volatile and volatile organic pollutants. | SHI Yan LUO ZiHao WANG YiXuan CAI MaoLin YANG LiMan | 2019 | Science China(Technological Sciences)2019，62，11： | 7 |
| 2 | A method for satellite time series anomaly detection based on fast-DTW and improved-KNN显示文摘In satellite anomaly detection,there are some problems such as unbalanced sample distribution,fewer fault samples,and unobvious anomaly characteristics.These problems cause the extisted anomaly detection methods are difficult to train accurate classification model,and the accuracy of anomaly detection is hard to improve.At the same time,the monitoring data of satellite has high dimension and is difficult to extract effective features.Based on the DTW over-sampling method,this paper realizes the over-sampling of fault samples in satellite time series,and constructs a distributed and balanced time series data set.The Fast-DTW method is applied to calculate the distance between different time series,which can improve the speed of similarity calculation.KNN(K-Nearest Neighbor)method is applied for classification and the best classification result is obtained by search the optimal hyper-parameters k.The results show that the proposed method has high anomaly detection accuracy and consumes short calculation time. | Langfu CUI Qingzhen ZHANG Yan SHI Liman YANG Yixuan WANG Junle WANG Chenggang BAI | 2023 | Chinese Journal of Aeronautics2023，36，2： | 7 |
| 3 | Caking property and active components of coal based on group component separation显示文摘The content and the caking index of the heavy,the dense medium and the loose medium components of coal,obtained by extraction and stripping with CS_2/N-methyl-2-pyrrolidinone mixed solvent(1:1 by volume),were studied and correlated with the caking property of raw coals.Images of the three group components after heat treatment were analyzed.The results show that both caking index(G) and maximum thickness of plastic layer(Y) of coals have a good linear relationship with the content of the medium component;the dense medium and the loose medium components are the two key factors to determine the caking property of raw coals-they are the source materials of fluidity and swelling of coal,respectively;the heavy component without the swelling and fluidity was cohered by the other components;two new indexes,which can extend current understanding of the caking properties,were introduced. | Qin Zhihong Li Xiang Sun Hui Zhao Cuicui Rong Liman | 2016 | International Journal of Mining Science and Technology2016，26，4： | 6 |
| 4 | 建设标准化的城市轨道交通云和大数据平台显示文摘鉴于全国各地城市轨道交通(以下简称“城轨”)建设起步不一且所处阶段不同,特别是对“城轨+信息化”的认识程度深浅有别以及信息化标准因地而异,致使各城市的城轨信息化进程参差不齐,应用程度和水平高低不一。与此同时,随着云计算、大数据、物联网、人工智能及5G等新兴信息技术的飞速发展,城规信息化、智能装备、指挥城规的建设步伐也随之加快。 | 李中浩 ZHANG Liman(译) | 2021 | 城市轨道交通研究2021，24，6： | 5 |
| 5 | 发展智慧城轨 助力智慧城市与交通强国建设显示文摘2020年3月12日,《中国城市轨道交通智慧城轨发展纲要》(以下简称《纲要》)以中城轨〔2020〕10号文件正式颁布实施。《纲要》以习近平新时代中国特色社会主义思想为根本遵循,将智慧城轨建设作为交通强国建设的重要支撑之一。“交通强国”和“智慧城市”建设是以习近平为核心的党中央、国务院的战略部署,是新时代实现交通高质量发展的必由之路。城轨行业必须坚持把智慧城轨作为“交通强国”和“智慧城市”建设的总抓手,统筹规划,系统推进。 | 周晓勤 ZHANG Liman(翻译) | 2020 | 城市轨道交通研究2020，23，5： | 5 |
| 6 | 高铁智能化——中国铁路又出发显示文摘2019年12月30日,世界上首条采用北斗卫星导航的智能高铁--京张高铁开通运营。110年前的1909年10月2日,中国第一条不使用外国资金及人员,由中国人自行设计、建造的京张铁路正式通车。遥想当年,中国要建京张铁路的消息一经传出,外国人便嘲讽'建造这条铁路的中国工程师尚未出生'。詹天佑创造性地在八达岭路段修建了'之'字形线路,使工程费用缩减为外国人预估的1/5;并利用'竖井施工法'开挖隧道,缩短了工期。足见从京张铁路到京张高铁,中国铁路在自主创新的轨道上从不停步,砥砺前行。 | 孙章 ZHANG Liman | 2020 | 城市轨道交通研究2020，23，2： | 4 |
| 7 | 强力推进智慧城市轨道交通建设显示文摘随着我国城市化率的不断提升,特大城市、大城市的数量快速增加,建设与智慧社会相匹配的智慧城市轨道交通(以下简称'城轨')已成为推进交通强国建设的一项重要任务。建设智慧城轨的战略指向是:在自主创新基础上,大力应用数字化、智能化、网络化等新技术革命成果,使之与城轨深度融合,推进城轨信息化,大力发展智能系统、建设智慧城轨。经多次讨论并反复征求领导和专家意见后,《中国城市轨道交通智慧城轨发展纲要》(以下简称《纲要》)已于2020年3月12日以中城轨[2020]10号文件正式颁布实施。 | 包叙定 Zhang Liman | 2020 | 城市轨道交通研究2020，23，4： | 4 |
| 8 | A BODIPY-based Fluorescent Probe for Thiophenol显示文摘 | Dongxiang Zhang Ning Xu Liman Xian Haoying Ge Jiangli Fan Jianjun Du Xiaojun Peng | 2018 | Chinese Journal of Chemistry2018，36，2： | 3 |
| 9 | Profiling of hepatocellular carcinoma neoantigens reveals immune microenvironment and clonal evolution related patterns显示文摘Objective: Neoantigens derived from tumor-specific genomic alterations have demonstrated great potential for immunotherapeutic interventions in cancers. However, the comprehensive profile of hepatocellular carcinoma(HCC) neoantigens and their complex interplay with immune microenvironment and tumor evolution have not been fully addressed.Methods: Here we integrated whole exome sequencing data, transcriptome sequencing data and clinical information of 72 primary HCC patients to characterize the HCC neoantigen profile, and systematically explored its interactions with tumor clonal evolution, driver mutations and immune microenvironments.Results: We observed that higher somatic mutation/neoantigen load was associated with better clinical outcomes and HCC patients could be further divided into two subgroups with distinct prognosis based on their neoantigen expression patterns. HCC subgroup with neoantigen expression probability high(NEP-H) showed more aggressive pathologic features including increased incidence of tumor thrombus(P=0.038), higher recurrence rate(P=0.029),more inclined to lack tumor capsule(P=0.026) and with more microsatellite instability sites(P=0.006). In addition,NEP-H subgroup was also characterized by higher chance to be involved in tumor clonal evolution [odds ratio(OR)=46.7, P<0.001]. Gene set enrichment analysis revealed that upregulation of MYC and its targets could suppress immune responses, leading to elevated neoantigen expression proportion in tumor cells. Furthermore, we discovered an immune escape mechanism that tumors could become more inconspicuous by evolving subclones with less immunogenicity. We observed that smaller clonal mutation clusters with higher immunogenicity in tumor were more likely to involve in clonal evolution. Based on identified neoantigen profiles, we also discovered series of neoantigenic hotspot genes, which could serve as potential actionable targets in future.Conclusions: Our results revealed the landscape of HCC neoantigens and discovered two clinically relevant subgroups with distinct neoantigen expression patterns, suggesting the neoantigen expression should be fully considered in future immunotherapeutic interventions. | Zhenli Li Geng Chen Zhixiong Cai Xiuqing Dong Lei He Liman Qiu Yongyi Zeng Xiaolong Liu Jingfeng Liu | 2021 | Chinese Journal of Cancer Research2021，33，3： | 3 |
| 10 | Structural basis for specific flagellin recognition by t ~ILR protein NAIP5显示文摘充满域的核苷酸绑定和包含蛋白质(NLR ) 的充满白氨酸的重复(LRR ) 作为细胞内部的有免疫力的受体工作检测导出病原体或导出主人的信号的存在。NLR 怎么察觉到他们的 ligands 的机制留下逃犯。这里,我们与 cryo 电子显微镜学在 4.28 点决定的 NLR 蛋白质 NAIP5 和 NLRC4 在建筑群报导细菌的 flagellin 衍生物的结构吗?分辨率。结构表明 flagellin 衍生物形成包括 NAIP5 的 BIR1 和 LRR 与多重领域交往的二平行 helices。对在 flagellin 衍生物的将近完全的埋葬的 NAIP5 结果有约束力,因此稳定 NAIP5 的活跃符合构造。flagellin 的极端 C 终端方面被抛锚到 NAIP5 的一个位地抑制的有约束力的衣袋,它多半由 NAIP5 为不同细菌的 flagellins 的辨别充当一个结构的决定因素,一个观点进一步由生物化学的数据支持了。一起拿,我们的结果使位于 NLR ligand 下面的分子的机制清楚些感觉。 | Xinru Yang Fan Yang Weiguang Wang Guangzhong Lin Zehan Hu Zhifu Han Yijun Qi Liman Zhang Jiawei Wang Sen-Fang Sui Jijie Chai | 2018 | Cell Research2018，28，1： | 2 |
| 11 | 新冠肺炎疫情防控与新型城市轨道交通系统开发显示文摘新冠肺炎疫情防控工作给我们的一大启示是:全社会需要大力加强公共卫生以及传染病防治领域的供给侧改革。为了从容应对各种疫情,让疫情对社会经济的影响降到最小,国家应建设完善的公共卫生与防疫基础设施。而对于城市公共交通网络中的主要组成部分——轨道交通,也应是完善公共卫生与防疫基础设施中的重要一环。 | 孙章 ZHANG Liman(Translated) | 2020 | 城市轨道交通研究2020，23，3： | 2 |
| 12 | Promotion of cardiac differentiation of brown adipose derived stem cells by chitosan hydrogel for repair after myocardial infarction显示文摘 | Haibin Wang Jinxin Shi Yan Wang Yujing Yin Liman Wang Jianfeng Liu Zhiqiang Liu Cuimi Duan Ping Zhu Changyong Wang | 2014 | Biomaterials2014，，： | 2 |
| 13 | Effect of methanolic extract of Tetrapleura tetraptera(Schum and Thonn)Taub leaves on hyperglycemia and indices of diabetic complications in alloxan-induced diabetic rats显示文摘Objective:To investigate the ameliorative role of Tetrapleura tetraplera(Schum and Thonn)Taub(T.tetraplera)leaf in hyperglycemia with associated conditions like oxidative stress,kidney damage and disorders in lipid metabolism.Methods:Five groups of five rats each intraperitoneally received the following treatment schedules for 7 d:untreated normal control,untreated alloxan-diabetic control,diabetic treated with glibenclamide,normal rats treated with extract(50 mg/kg)and diabetic rats treated with the extract.Evaluations were made for fasting blood sugar,body weight changes,malondialdehyde,aspartate aminotransferase,alanine aminotransferase,bilirubin,superoxide dismutase,catalase,lipid profile,packed cell volume,hemoglobin,urea and creatinine in all the rats.Results:Whereas the untreated diabetic rats showed a significant decrease(P<0.05)in packed cell volume,superoxide dismutase,catalase and high-density lipoprotein-cholesterol with a concomitant increase in the levels of malondialdehyde,fasting blood sugar,aspartate aminotransferase,alanine aminotransferase,bilirubin,urea and creatinine,administration of methanolic extract of T.tetraplera leaf or glibenclamide alleviated these altered parameters in the treated rats.Conclusions:Methanolic extract of T.tetraplera leaves possesses a potent capacity for treatment of diabetes and the accompanying complications,including oxidative stress and hyperlipidemia. | Sunday Ene-Ojo Atawodi Ojochenemi Ejeh Yakubu Mubarak Labaran Liman Dorothy Uju iliemene | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，4： | 1 |
| 14 | Dna computing on surfaces显示文摘 | Liu Q Liman W | 2000 | Nature2000，，403： | 1 |
| 15 | Expression of vascular en- dothelial growth factor receptors and their ligands in rat ute- rus during the postpartum involution period 显示文摘 | Sagsoz H Liman N Alan E | 2015 | Biotech Histochem2015，，： | 1 |
| 16 | Object segmentation using ant colony optimization algorithm and fuzzy entropy显示文摘 | Tao Wenbing Jin Hai Liu Liman | 2007 | Pattern Recognition letters2007，28，7： | 1 |
| 17 | Clinicaland radiological differences in posterior reversibleencephalopathy syndrome betweenpatients withpreeclampsia-eclampsia and other predisposing diseases显示文摘 | Liman TG Bohner G Heuschmann PU | 2012 | Eur J Neurol2012，19，7： | 1 |
| 18 | New vessels alter stroke: postischemie neo- vascularization and regeneration 显示文摘 | Liman TG Endres M | 2012 | Cerebrovasc Dis2012，33，5： | 1 |
| 19 | Mass culture of mammalian cells显示文摘 | Mc Limans W F | 1979 | Methods in Enzymology1979，58，： | 1 |
| 20 | Gas Leakage Detection and Pressure Difference Identification by Asymmetric Differential Pressure Method显示文摘Currently,the measurement methods for pneumatic system leakage include bubbling,ultrasonic,and pressure detection methods.These methods are sensitive to high-precision sensors,long detection times,and stable external environments.The traditional differential pressure method involves severe differential pressure fluctuations caused by environmental pressure fluctuations or electromagnetic noise interference of sensors,leading to inaccurate detection.In this paper,a differential pressure fitting method for an asymmetric differential pressure cylinder is proposed.It overcomes the limitation of the detection efficiency caused by the asynchronous temperature recovery of the two chambers in the asymmetric differential pressure method and uses the differential pressure substitution equation to replace the differential calculation of the differential pressure.The improved differential pressure method proposes an innovation based on the detection principle and calculation method.Additionally,the influence of the parameters in the differential pressure substitution equation on the leakage calculation results was simulated,and the specific physical significance of the parameters of the differential pressure substitution equation was explained.The experiments verified the fitting effect and proved the accuracy of this method.Compared with the traditional differential pressure method,the maximum leakage deviation of inhibition was 0.5 L/min.Therefore,this method can be used to detect leaks in air tanks. | Yan Shi Jiaqi Chang Yixuan Wang Xuelin Zhao Qingzhen Zhang Liman Yang | 2022 | Chinese Journal of Mechanical Engineering2022，35，2： | 1 |
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