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1Report of an international workshop to standardize baseline evaluation and response criteria for primary CNS lymphoma.显示文摘Abrey LE Batchelor TT Ferreri A J Gospodarowicz M Pulczynski EJ Zucca E Smith JR Korfel A Soussain C DeAngelis LM Neuwelt EA O′Neill BP Thiel E Shenkier T Graus F van den Bent M Seymour JF Poortmans P Armitage JO Cavalli F 2005中国神经肿瘤杂志2005,3,3:53
2急性儿茶酚胺暴露引起可逆的无心脏细胞再生的心肌细胞损伤显示文摘儿茶酚胺增加心脏收缩力,但暴露于高浓度儿茶酚胺或长时间暴露可引起心脏损伤。最近的一项研究表明,小鼠单次皮下注射异丙肾上腺素(isoproterenol,ISO;200 mg/kg)导致急性心肌细胞死亡(8%-10%),但在1个月之内心脏完整修复。心脏再生是通过内源性原癌基因蛋白质cKit+心脏干细胞介导新的心肌细胞形成。刘莉 叶鹏 Wallner M Duran JM Mohsin S Troupes CD Vanhoutte D Borghetti G Vagnozzi RJ Gross P Yu D Trappanese DM Kubo H Toib A Sharp TE Harper SC Volkert MA Starosta T Feldsott EA Berretta RM Wang T Barbe MF Molkentin JD Houser SR 2016中华高血压杂志2016,24,8:4
3弓形虫感染引起小胶质细胞与神经元的接触以及细胞体周边抑制性突触丧失显示文摘大脑内的感染和炎症会引起神经元连通性和功能的改变。细胞内的原生动物寄生虫,弓形虫,是一种感染脑部的病原体,可引起脑炎和癫痫发作。这种寄生虫的持续感染还与行为改变和发生精神疾病(包括精神分裂症)的风险增加有关。目前来自人类和小鼠模型的研究证据表明,癫痫发作和精神分裂症均由抑制性突触的丧失或功能障碍引起。与此相符,我们最近报道了持续性弓形虫感染改变谷氨酸脱羧酶67(GAD67)的分布,该酶在抑制性突触中催化GABA的合成。这些变化可能反映突触前装置在抑制性神经元中的重新分布或抑制性神经末梢的丧失。为了直接评估后者的可能性,我们采用序列块面扫描电子显微镜(SBFSEM)并量化寄生虫感染后新皮质和海马中的细胞体周边抑制性突触。持续感染不仅导致明显的细胞体周边突触丧失,而且还诱导髓样来源的细胞对神经元细胞体的包封。免疫组织化学、遗传和超微结构分析显示,这些髓样来源的细胞包括活化的小胶质细胞。最后,超微结构分析确定了包膜于细胞体周围神经末梢的髓样来源的细胞,提示它们可能会主动置换或吞噬突触元件。因此,这些结果表明,活化的小胶质细胞有助于寄生虫感染后细胞体周围抑制突触损失,并对于弓形虫的持续感染可能如何导致癫痫发作和精神疾病提供了一种新的机制。Carrillo GL Ballard VA Glausen T Boone Z Teamer J Hinkson CL Wohlfert EA Blader IJ Fox MA 杜一星(编译) 2020神经损伤与功能重建2020,15,3:2
4Cell spreadingand focal adhesion dynamics are regulated by spacing of integrinligands显示文摘Cavalcanti-Adam EA Volberg T Micoulet A 2007Biophys J2007,92,8:1
5Concurrent administration of interferon alfa-2b and beta-la显示文摘Tanvetyanon T Stadtmauer EA Kerson LA 2003Ann Pharmacother2003,37,1:1
6Differences in somatic perception in female patients with irritable bowel syndrome with and without fibromyalgia 显示文摘Chang L Mayer EA Johnson T 2000Pain2000,84,23:1
7Mitochondrial DNA and the mammalian oocyte 显示文摘Shoubridge EA Wai T 2007Curr Top Dev Biol2007,77,:1
8Cellular and physiologicalmechanisms underlying blood flow regulation in the retinachoroid in health disease显示文摘Kur J Newman EA Chan-Ling T 2012Proq Retin Eye Res2012,31,:1
9Age-dependent associations between chronic periodontitis/edentulism and risk of coronary heart disease显示文摘Dietrich T Jimenez M Krall Kaye EA 2008Circulation2008,117,13:1
10NO induced migraine attack:strong increase in plasma calcitonin gene-related peptide(CGRP)con-centration and negative correlation with platelet serotonin release显示文摘Juhasz G Zsombok T Modos EA 2003Pain2003,106,3:1
11Calture of human endothelial cells derived from umbilical veins indentification by mrophdogic and immunology criteria显示文摘Jaffe EA takahara T Yamaguchi N 1973J Clin Invest1973,52,:1
12Benzopyrene, but Not 2, 3, 7, 8-TCDD, induces G2/M cell cycle arrest, p21CIP1 and p53 phosphorylation in human choriocarcinoma JEG-3 cels: a distinct signaling pathway显示文摘Drukteinis JS Medrano T Ablordeppey EA 2005Placenta2005,26,:1
13Pathogenic flavivirus-es显示文摘Gould EA Solomon T 0,,:1
14NO-induced migraine attack: strong increase in plasma calcitonin gene related peptide (CGRP) eoncentrationand negative correlation with platelet serotonin release显示文摘Juhasz G Zsombok T Modos EA 2003Pain(0340 - 3959)2003,106,3:1
15Dlk, a putative mammalian homeotic gene differentially expressed in small cell lung carcinoma and neuroendocrine tumor cell line显示文摘Laborda J Sausville EA Hoffman T 1993J Biol Chem1993,268,6:1
16Serum interleukin45 soluble receptor in relation to interleukin-6 in stroke patients 显示文摘Dziedzic T Gryz EA Turaj W 2004J Mol Neurosci2004,24,2:1
17Molecular evolution of the HSP70 multigene family显示文摘Boorstein WR Ziegelhoffer T Craig EA 1994J Mol Euo1994,38,:1
18Biopsy of anterior Mediastinal masses under local anesthesia 显示文摘Rendina EA Venuta F De Giacoma T 2002Ann Thorac Surg2002,74,5:1
19Serum interleukin-6 soluble receptor in relation to interleukin-6 in stroke patients 显示文摘Dziedzic T Gryz EA Turaj W 2004J Mol Neurosei2004,24,:1
20Understanding and treating lateral ankle sprains and their consequences: a con- straints-based approach显示文摘Wikstrom EA Hubbard-Turner T McKeon PO 2013Sports Med2013,43,6:1
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