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| 1 | Performance of low-cost ejectors显示文摘 | Lima Neto I E De Melo Porto R | 2004 | Journal of Irrigation and Drainage Engineering2004，130，2： | 1 |
| 2 | Aframework for integrating non-functionalrequirements into conceptual models显示文摘 | Cysneiros Luiz Marcio Julio Cesar Sampaio doPrado Leite Jaime de Melo Sabat Neto | 2001 | Requirements Eng2001，6，： | 1 |
| 3 | Adenosinerich elements present in the 5'-untranslated region of PABP mRNA can selectively reduce the abundance and translation of CAT mRNAs in vivo显示文摘 | Eduardo O M Osvaldo P de Melo Neto | 2003 | FEBS Letters2003，，546： | 1 |
| 4 | Orthotopic Liver Transplantation Without Venovenous Bypass: 125 Cases From a Single Center显示文摘 | L.E.C. Miranda P.S.V. de Melo B.D. Sabat A.L. Tenório D.L. Lima O.C.L.F. Neto A.G. Amorim J.L. Fernandez F.I.B. de Macedo C.M. Lacerda | 2012 | Transplantation Proceedings2012，，8： | 1 |
| 5 | Treatment of hemorrhage intracranial dissections显示文摘 | Anxionnat R de Melo Neto JF Bracard S | 2003 | Neurosurgery2003，53，2： | 1 |
| 6 | Systemic inflammatory response secondary to abdomi- nal compartment syndrome: stage for multiple organ fail- ure显示文摘 | Rezende Neto J B Moore E E Melo de Andrade M V | 2002 | J Trauma2002，53，6： | 1 |
| 7 | Cross-sectional study to determine viral hepatitis knowledge in different urban populations in Brazil显示文摘AIM To evaluate viral hepatitis knowledge among individuals from different resource areas and health conditions to identify possible gaps.METHODS A cross-sectional, descriptive study was carried out among 447 individuals from five distinct populations in Brazil: Southeast Viral Hepatitis Ambulatory(n = 100), South(n = 89) and Northeast(n = 114) Health Center, Southeast(n = 77) and Northeast(n = 67) low resource areas. All individuals answered a questionnaire assessing sociodemographic characteristics and viral hepatitis awareness. The perception was scored based on the average number of correct answers of all participants and categorized as 'low'(0-28 correct answers) or 'desirable'(29-46 correct answers). Associations between sociodemographic characteristics and perception were also evaluated.RESULTS A low level of knowledge was observed in individuals from Northeast Health Center, Northeast and Southeast low resource areas while desirable knowledge was observed in individuals from Viral Hepatitis Ambulatory and South Health Center. According to sociodemographic characteristics, desirable scores were more common among those with secondary education(47.1%), those who declared themselves as white(46.3%), and those who lived in houses with three individuals(25.5%). Multivariate analysis showed an association between viral hepatitis perception and type of population. CONCLUSION The results demonstrated high level of knowledge among study participants from health clinics from the Southeast region of Brazil and the importance of education programs in increasing the level of knowledge in low resource areas. | Helena Medina Cruz Jakeline Ribeiro Barbosa Jeová Keny Baima Colares Antonio Henrique Almeida de Moraes Neto Maria de Fátima Leal Alencar Francisco Inácio Bastos Jurema Corrêa da Mota Filipe Aníbal Carvalho-Costa Claudia Alexandra Pontes Ivantes Lia Laura Lewis-Ximenez Livia Melo Villar | 2018 | World Journal of Hepatology2018，10，11： | 1 |
| 8 | Treatment of hemorrhage intracranial dissections 显示文摘 | Anxionnat R Ferreira de Melo Neto 1 Bracard S | 2003 | Neur~sttrgetT2003，53，： | 1 |
| 9 | Treatment of hemorrhagic intracranial dissections显示文摘 | Anxionnat R de Melo Neto JF Bracard S | 2003 | Neurosurgery2003，53，： | 1 |
| 10 | Medicinal plants of the caatinga (semi-arid) vegetation of NE Brazil: A quantitative approach显示文摘 | Ulysses Paulino de Albuquerque Patrícia Muniz de Medeiros Alyson Luiz S. de Almeida Júlio Marcelino Monteiro Ernani Machado de Freitas Lins Neto Joabe Gomes de Melo Janaina Patrícia dos Santos | 2007 | Journal of Ethnopharmacology2007，，3： | 1 |
| 11 | Treatment of hemorrhagic intracranial diseases显示文摘 | Anxionnat R de Melo Neto JF Bracard S | 2003 | Neurosurgery2003，53，2： | 1 |
| 12 | Vibrio spp.from Macrobrachium amazonicum prawn farming are inhibited by Moringa oleifera extracts显示文摘Objective:To investigate the in vitro antimicrobial potential of extracts of stem,leaves,flowers,pods and seeds of Moringu okifera(M.okifera) against Vibrio spp.from hatchery water and the prawn Mmrobrachium amazonicum.Methods:The ethanol extracts of stem,leaves,pods and seeds and chloroform extract of flowers of M.oleifera were tested against Vibrio cholerue(V.cholerae) serogroups non-O1/non-O139(n=4).Vibrio vulnificus(n=l) and Vibrio mimicus(n=1).Escherichia coli(E.coli)(ATCC(?) 25922) was used as quality control.Vibrio species were obtained from Macmbrachium amazonicum prawns and from hatchery water from prawn farming.The Minimum Inhibitory Concentration(MIC) was determined by broth microdilution method.Results:The best result was obtained with the ethanol extract of pods,which inhibited three strains of the V.choleme,Vibrio vulnificus,Vibrio minimis and E.coli(MIC range 0.312-5.000 mg/mL).The chloroform extract of flowers was effective against all V.chokrae strains and E.coli(MIC range 0.625-1.250 mg/mL).However,the ethanol extracts of stem and seeds showed low effectiveness in inhibiting the bacterial growth.Conclusions:The extracts of pods,flowers and leaves of M.oleifera have potential for the control of Vibrio spp.Further studies are necessary to isolate the bioaetive compounds responsible for this antimicrobial activity. | Raimunda Samia Nogueira Brilhante Jamille Alencar Sales Celia Maria de Souza Sampaio Francisco Geraldo Barbosa Manoel de Araujo Neto Paiva Glaucia Morgana de Melo Guedes Lucas Pereira de Alencar Yago Brito de Ponte Tereza de Jesus Pinheiro Gomes Bandeira Jose Luciano Bezerra Moreira Debora de Souza Collares Maia Castelo-Branco Waldemiro de Aquino Pereira-Neto Rossana de Aguiar Cordeiro Jose Julio Costa Sidrim Marcos Fabio Gadelha Rocha | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，11： | 1 |
| 13 | Treatment of hemorrhagic intracranial dissections 显示文摘 | Anxionnat R de Melo Neto JF Braeard S | 2008 | Neurosurgery2008，62，63： | 1 |
| 14 | Treatment of hemorrhage intracranial dissections显示文摘 | Anxionnat R Ferreira de Melo Neto J Bracard S | 2003 | Neurosurgery2003，53，2： | 1 |
| 15 | Physiological responses to salt stress in young umbu plants显示文摘 | Elizamar Ciríaco da Silva Rejane Jurema Mansur Custódio Nogueira Francisco Pinheiro de Araújo Natoniel Franklin de Melo André Dias de Azevedo Neto | 2007 | Environmental and Experimental Botany2007，，1： | 1 |
| 16 | Use of conducting polypyrrole blends as gas sensors 显示文摘 | de Melo C P Neto B B de Lima E G | 2005 | Sensors and Actuators B2005，109，： | 1 |
| 17 | Medicinal plants in the healing of dry socket in rats: microbiological and microscopic analysis 显示文摘 | De MELO E J M Jr RAPOSO M J NETO J A L | 2002 | Phytomedicine2002，9，2： | 1 |
| 18 | Performance of low-cost ejectors显示文摘 | Neto I E L De Melo Porto R | 2004 | Journal of Irrigation and Drainage Engineering2004，130，2： | 1 |
| 19 | Antibacterial activity and inhibition against Staphylococcus aureus NorA efflux pump by ferulic acid and its esterified derivatives显示文摘Objective:To evaluate the inhibitory activity of ferulic acid and four of its esterified derivatives(methyl,ethyl,propyl,and butyl)against resistance mechanisms in Staphylococcus aureus strains.Methods:Ferulic acid derivatives were obtained by esterification with methanol,ethanol,propanol,and butanol,and then characterized by hydrogen and carbon-13 nuclear magnetic resonance analysis.The minimum inhibitory concentrations(MIC)of ferulic acid and its esterified derivatives,ethidium bromide,and norfloxacin were obtained using the microdilution test,while the efflux pump inhibition test was conducted by examining reduction in the MICs of norfloxacin and ethidium bromide.Molecular docking was also carried out using the Schrodinger Suite 2015 molecular modeling software.A three-dimensional model of NorA efflux pump was generated using I-TASSER.The best scoring model was used as a receptor for ligand-receptor docking.Results:The methyl and butyl ester derivatives did not demonstrate significant antimicrobial activity.However,a significant synergic effect was evidenced when norfloxacin was combined with the ethyl and propyl esterified derivatives.The docking study demonstrated favorable energy of interaction between ferulate derivatives and NorA,and amino acid residues TYR57,TYR58,and LEU255 were present commonly in stabilizing all complexes.The PCA analysis corroborated the docking hypothesis that the lipophilic character and hydrogen bond interactions were the most relevant characteristics involved with NorA inhibitors.The pharmacokinetic parameters of ferulic acid derivatives showed good ADMET properties,demonstrating that they can be easily absorbed and have no effect or inhibit the cytochrome P450 enzyme complex,revealing their potential as drug candidates.Conclusions:This study provides strong evidence that the molecular basis for this activity is potentially due to the NorA efflux pump. | Patrícia Gonçalves Pinheiro Gilvandete Maria Pinheiro Santiago Francisco Erivaldo Freitas da Silva Ana Carolina Justino de Araújo Cícera Rejane Tavares de Oliveira Priscilla Ramos Freitas Janaína Esmeraldo Rocha JoséBezerra de Araújo Neto Maria Milene Costa da Silva Saulo Relison Tintino Irwin Rose Alencar de Menezes Henrique Douglas Melo Coutinho JoséGalberto Martins da Costa | 2021 | Asian Pacific Journal of Tropical Biomedicine2021，11，9： | 0 |
| 20 | Enterobacteria and Vibrio from Macrobrachium amazonicum prawn farming in Fortaleza,Ceará,Brazil显示文摘Objective:To investigate the isolation of enterobacteria associated with Macrobrachium amazonicum(M.amazonicum) farming and evaluate the in vitro antimicrobial susceptibility of Vibrio strains.Methods:Strains were isolated from female M.amazonicum prawns and environmental and hatchery water.Biochemical assays were used to identify bacterial genera and those belonging to the genus Vibrio were submitted to further analyses for species identification,through Vitek 2 automated system and scrotyping.Susceptibility test was performed according to Clinical Laboratory Standards Institute.Results:The following genera of enlerobacteria were recovered:Enterobacter(n=11),Citrobacter(n=10),Proteus(n=2),Serratia(n=2),Kluyvera(n=2),Providencia(n=2),Cedecea(n=1),Escherichia(n=1).Edwardsiella(n=1) and BulliauxeUa(n=1).As for Vibrio,three species were identified:Vibrio cholerae non-O1/non-O139(n=4).Vibrio vulnificus(V.vulnificus)(n=1) and Vibrio mimicus(n=1).Vibrio spp.showed minimum inhibitory concentrations values within the susceptibility range established by Clinical Laboratory Standards Institute for almost all antibiotics,except for V.vulnificus,which presented intermediate profile to ampicillin.Conclusions:Enterobacteria do not seem to be the most important pathogens associated with M.amazonicum farming,whereas the recovery of Vibrio spp.from larviculture,with emphasis on Vibrio cholerae and V.vulnificus,deserves special attention due to their role as potentially zoonotic aquaculture-associated pathogens.Furthermore,the intermediate susceptibility of V.vulnificus to ampicillin reflects the importance of monitoring drug use in prawn farming. | Débora de Souza Collares Maia Castelo-Branco Jamille Alencar Sales Raimunda Samia Nogueira Brilhante Glaucia Morgana de Melo Guedes Yago Brito de Ponte Celia Maria de Souza Sampaio Tereza de Jesus Pinheiro Gomes Bandeira José Luciano Bezerra Moreira Lucas Pereira de Alencar Manoel de Araújo Neto Paiva Rossana de Aguiar Cordeiro André Jalles Monteiro Waldemiro de Aquino Pereira-Neto José Júlio Costa Sidrim Marcos Fábio Gadelha Rocha | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，1： | 0 |
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