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| 1 | 三联药物治疗宫颈鳞状上皮内瘤变患者LEEP术后高危型HPV持续感染的效果显示文摘目的采用匹多莫德配伍利巴韦林片及重组人干扰素α2b栓三联药物治疗宫颈鳞状上皮内瘤变(CIN)患者宫颈高频电波刀电圈切除术(LEEP)后高危型人乳头状瘤病毒(HR-HPV)持续感染的临床效果。方法选取2014年6月至2015年12月在安徽省妇幼保健院宫颈疾病中心就诊、经宫颈疾病三阶梯筛查联合第二代杂交捕获实验(HC-2)证实CIN病变合并HR-HPV感染,行LEEP术、术后1年仍为HR-HPV持续感染者,共70例患者,按随机数字表法分为对照组与试验组,每组35例。试验组采用匹多莫德配伍利巴韦林片及重组人干扰素α2b栓三联药物治疗,对照组仅使用重组人干扰素α2b栓治疗。两组患者均在停药3个月后进行液基细胞学检测(TCT)、HC-2检查。结果药物治疗3个月后,两组患者TCT结果差异有统计学意义(χ~2=8.403,P=0.038);对照组复查HR-HPV阳性率高于试验组,差异有统计学意义(χ~2=4.629,P=0.031);对照组、试验组患者病毒DNA载量分别为(19.14±62.07)和(0.96±2.67),两组差异无统计学意义(t=9.056,P=0.004)。结论匹多莫德配伍利巴韦林片及重组人干扰素α2b栓三联药物治疗能有效降低HR-HPV持续感染,值得推广应用。 | 周曙光 刘波 谢婷婷 陈果 张华 张和平 BOBOLE Amos | 2018 | 安徽医学2018，39，3： | 22 |
| 2 | 皮质下小血管病诊断的共识声明显示文摘血管性认知损害是用于描述一组涉及大血管和小血管的散发性和遗传性异质性疾病的诊断术语。皮质下小血管病可导致腔隙性梗死和进行性白质损害。被称为宾斯旺格病(Binswanger's disease, BD)的进行性白质损害患者构成了从单纯血管性疾病到合并神经变性病变的疾病谱。BD患者是一个相对同质性的亚组,存在缺氧缺血、腔隙性梗死和炎症,它们协同作用破坏血脑屏障和髓鞘。通过临床、脑脊液、神经心理学和影像学检查获得的多模式疾病标记物能促进该亚组患者的鉴别。本共识声明确定了一系列基于基础病理学改变的潜在生物学标记物,这将有助于诊断以及将来协作性治疗试验的患者选择。 | Gary A Rosenberg Anders Wallin Joanna M Wardlaw Hugh S Markus Joan Montaner Leslie Wolfson Costantino Iadecola Berislav V Zlokovic Anne Joutel Martin Dichgans Marco Duering Reinhold Schmidt Amos D Korczyn Lea T Grinberg Helena C Chui Vladimir Hachinski 王训师 张劼 陈涵丰 俞娅美 徐子奇 罗本燕 | 2016 | 国际脑血管病杂志2016，24，6： | 18 |
| 3 | A review of the development of full cell lithium-ion batteries: The impact of nanostructured anode materials显示文摘锂离子电池为消费者电子学市场作为最好的便携式的精力存储设备出现了。在 lithiumion 电池的开发的最近的进步被选择阳极材料的使用获得了,它以能力,周期的稳定性,和率能力在性能驾驶了改进。在这方面,研究集中于设计和完整的房间锂离子电池的电气化学的性能,最新利用开发了阳极材料,广泛地被报导了,并且在开发的大迈进被做了。Nanostructured 阳极材料主要作出贡献到完整的房间锂离子电池的发展。与这在头脑,我们在硬币房间的表演总结 nanostructured 阳极材料的影响完整的锂离子电池。这评论也讨论对完整的房间锂离子电池的研究的挑战和前景。 | Muhammad-Sadeeq Balogun Weitao Qiu Yang Luo Hui Meng Wenjie Mai Amos Onasanya Titus K. Olaniyi Yexiang Tong | 2016 | Nano Research2016，9，10： | 18 |
| 4 | 雪藻高密度连续培养中生物量和花生四烯酸的高产率显示文摘以 1 .4cm和 2 .8cm光径的平板光生物反应器 ,恒定高光强 [2 4 0 0 μE/(m2 ·s) ],通气、无菌高密度连续培养雪地绿藻 (简称雪藻 )。连续采收并补充等量新鲜培养液 ,当藻体生物量(以去灰分干重表示 ,AFDW)达恒态时 ,研究雪藻比生长速率 (SGR)、藻体的生物产量、总脂肪酸 (TFA)和花生四烯酸 (AA)产率。结果表明 ,尽管随着比生长速率增加 ,雪藻高密度连续培养体系的AA/TFA、TFA/AFDW和AA/AFDW三个指标有不同程度的降低 ,但生物产量、总脂肪酸及其花生四烯酸产出都相当高。 2 .8cm光径的平板光生物反应器中 ,雪藻SGR为0 .2d- 1 时 ,每平方米光照面积日获 35 .3gAFDW的高产量 ;SGR 0 .1 35d- 1 时 ,TFA产率最大 ,为7.0g/(m2 ·d) ,此时AA产率也最高 ,达 2 .6g/(m2 ·d)。尽管 1 .4cm光径的反应器的培养体积比前者下降了 5 0 % ,但细胞浓度明显提高 ,单位光照面积的AFDW和TFA最大日产率只下降了37.3%和 1 0 % ,分别为 2 2 .1和 6.3g/(m2 ·d) ,而AA的最大日产率也是 2 .6g/(m2 ·d)。结果还表明 ,氮或磷营养亏缺能明显提高雪藻AA含量的各项指标 ,同时高光强也有利于雪藻累积AA。 | 刘建国 刘伟 Zvi Cohen Amos Richmond | 2002 | 海洋与湖沼2002，33，5： | 15 |
| 5 | 腔镜微创食管癌切除术的学习过程分析显示文摘目的总结腔镜微创食管癌切除术(MIE)的学习过程。方法选取同一组医生连续完成的MIE手术100例,按手术时间顺序分为3组:第1、2组各25例行胸腔镜并常规开腹手术,第3组50例行胸腹腔镜手术.分别记录手术时间、出血量、正常结构保护及并发症发生情况、术后ICU观察时间、住院时间、术后肿瘤病理及淋巴结清扫情况等临床资料,比较各组之间的差异。结果全组中96例患者顺利完成MIE,4例患者中转开胸,无中转开腹。中位手术时间310min,中位失血量200ml,中位清扫淋巴结22枚,总体并发症发生率50%。第1组与第2组比较,在保留奇静脉弓(P=0.010)、保留支气管动静脉(P=0.038)及左侧喉返神经胸段术中暴露率(P=0.048)方面的差异有统计学意义。前50例与后50例比较,在胸部手术时间(P=0.000)、失血量(P=0.025)、保留奇静脉弓(P=0.001)、保留支气管动静脉(P=0.000)、胸野淋巴结清扫(P=0.022)、左喉返神经链淋巴结清扫(P=0.000)及该神经起始部术中暴露率(P=0.002)方面的差异有统计学意义。结论MIE学习过程较长.应循序渐进。随着经验的积累和手术技巧的提升.MIE将逐渐显示其独特的优势并替代传统开胸食管癌切除术。 | 谢绚 傅剑华 王军业 张旭 罗孔嘉 杨富 Amos Ela Bella 李小海 | 2012 | 中华胃肠外科杂志2012，15，9： | 15 |
| 6 | 前景理论:风险决策分析显示文摘本文批评了风险决策的描述性模型期望效用理论,并提出了一种替代性模型,称为前景理论。风险前景中的选择显示出几种与效用理论的基本原则不一致的普遍效应。特别是,相对于确定获得的结果,人们低估仅仅可能的结果。这种倾向称为磁定抛它可以归因于包括确定收益选择中的风险厌恶和包括确定损失选择中的风险寻求。 | Daniel Kahneman Amos Tversky 胡宗伟(译) | 2008 | 经济资料译丛2008，，1： | 14 |
| 7 | Advances in prospect theory: Cumulative representation of uncertainty显示文摘 | Amos Tversky Daniel Kahneman | 1992 | Journal of Risk and Uncertainty1992，，4： | 10 |
| 8 | Metabolic complications in liver transplant recipients显示文摘The metabolic syndrome(MS), which includes obesity,dyslipidaemia, hypertension and hyperglycaemia according to the most widely accepted definitions now used, is one of the most common post-transplant complications, with a prevalence of 44%-58%. The MS, together with the immunosuppression, is considered the main risk factor for the development of cardiovascular disease(CVD) in transplant recipients, which in turn accounts for 19%-42% of all deaths unrelated to the graft. The presence of MS represents a relative risk for the development of CVD and death of 1.78. On the other hand, non-alcoholic fatty liver disease(NAFLD), considered as the manifestation of the MS in the liver, is now the second leading reason for liver transplantation in the United States after hepatitis C and alcohol. NAFLD has a high rate of recurrence in the liver graft and a direct relation with the worsening of other metabolic disorders, such as insulin resistance or diabetes mellitus. Consequently, it is vitally important to identify and treat as soon as possible such modifiable factors as hypertension, overweight, hyperlipidaemia or diabetes in transplanted patients to thus minimise the impact on patient survival. Additionally, steroid-free regimens are favoured, with minimal immunosuppression to limit the possible effects on the development of the MS. | Miguel Jiménez-Pérez Rocío González-Grande Edith Omonte Guzmán Víctor Amo Trillo Juan Miguel Rodrigo López | 2016 | World Journal of Gastroenterology2016，22，28： | 10 |
| 9 | PHYSIOLOGICAL INHIBITORY EFFECT OF OCS IN ARACHIDONIC ACID-RICH PARIETOCHLORIS INCISA (TREBOUXIOPHYCEAE, CHLOROPHYTA)显示文摘Parietochloris incisa is an arachidonic acid rich snow green alga. The main physiological profiles, such as ash free dry weight (AFDW), chlorophyll, carotenoid, protein and total fatty acids (TFA), in this alga exposed to old culture supernatant (OCS) at the decline phase or its crude ethyl acetate extracts (CEAE) were investigated by using tubular photobioreactors of different diameters. Results showed that both OCS and CEAE had strong inhibitory effect on the above physiological parameters. The longer the culture was exposed to OCS and the more CEAE were added into the algal culture, the more the above physiological properties were inhibited. Arachidonic acid (AA), the dominant component of fatty acids in this alga, was also seriously inhibited with respect to total TFA, AFDW of cell mass, or culture volume, due to a probable reduction of enzymes activities catalyzing chain elongation from C18:1ω9 to AA. These results incontestably evidenced that some CEAE dissolving substances existing in OCS, like auto inhibitors, inhibited P. incisa growth through feedback. Hence, any efficient removal of auto inhibitors from algal culture to decrease their bioactivity could be good for maximal production of desired products like AA. | 刘建国 张成武 Zvi Cohen Amos Richmond | 2002 | Chinese Journal of Oceanology and Limnology2002，20，3： | 7 |
| 10 | 新型可回收全覆膜镍钛合金支架治疗难治性食管良性狭窄显示文摘目的探讨自行设计的新型可回收抗反流全覆膜镍钛合金支架治疗难治性食管良性狭窄的疗效。方法2009年11月至2011年5月间中山大学肿瘤防治中心胸科采用新型支架治疗难治性食管良性狭窄患者8例。在支架置入术后第1、7、30和60天以及拔除支架术后1、2、3和6个月,进行胃镜和食管吞钡检查,评价患者吞咽功能改善及并发症发生情况。结果8例患者均成功置入新型支架.术后吞咽功能较术前明显改善(P〈0.05)。经9个月的中位随访,已拔除支架6例,其吞咽功能亦较术前明显改善(P〈0.05):支架继续留置2例,其中1例支架置入术后已15个月,目前仍进普通饮食:另1例支架置入术后2个月吞咽功能较术前改善.但3个月后吞咽功能减退至术前水平。8例患者远期吞咽功能改善率为7/8。术后再狭窄1例:支架脱落2例:肉芽过度增生3例,其中支架覆膜破裂致肉芽向内生长2例。结论新型可回收全覆膜镍钛合金支架置入食管良性狭窄术后和拔除支架后吞咽功能明显改善.远期再狭窄发生率低:但支架脱落发生率仍较高.支架覆膜材料易破裂.仍需进一步改进。 | 李小海 胡祎 杨弘 Amos Ela Bella 傅剑华 | 2011 | 中华胃肠外科杂志2011，14，11： | 7 |
| 11 | Advances in prospect theory: Cumulative representation of uncertainty显示文摘 | Amos Tversky Daniel Kahneman | | Journal of Risk and Uncertainty0，，： | 6 |
| 12 | 枯竭老油田采油的地震监测和岩石物性研究显示文摘老油田上产新油的主攻目标是油田的可采油量与不可采油量(由于残留饱和度)之间的巨大差距。造成这种差距的主要原因是诸如油藏渗透率、孔隙压力、饱和度及压缩系数的不均匀分布。为描述这些不均匀分布,以岩石物性为解释基础的地震勘探显然是合适的方法。当前,结合岩石物性研究,地震方法体现为两种不同的用途:1)油藏描述;2)采油监测。油藏描述提供我们开采前油藏中流体流动的不均匀分布情况。采油监测通过重复地震观测,记录地震数据变化。这些变化是由于采油过程中地下流体压力或组份变化所造成的。用孔隙压力,流体及其温度的变化解释地震数据变化,对认识岩石当前的物理状态非常有用。因此该种监测必将成为采油管理、特别是在对非均匀油藏注水和蒸汽采油管理的关键技术。 | Amos Nur Li Fang | 1994 | 国外油气勘探1994，6，3： | 6 |
| 13 | Exporting National Champions:China's Outward Foreign Direct Investment Finance in Comparative Perspective显示文摘We examine the extent to which Chinese development banks have financed the globalization of China's 'national champion'firms:specifically,through outward foreign direct investment(OFDI).We create a database of Chinese finance for OFDI and compare our results to the existing literature and available data on Japan,Korea and other Asian nations.We estimate the total value of China 's OFDI finance from 2002 to 2012 at US$140bn.As a percentage of total OFDI,China's lending is roughly three times higher than Japan 's,the previous global leader in OFDI finance.We identify two major reasons for China 's high(31 percent)ratio of OFDI lending to total OFDI.First,China has a greater incentive to give OFDI loans than Japan or Korea ever did because its borrowers are state-owned so it can more easily channel funds to targeted areas.Second,China has a greater capacity to give OFDI loans because it has significantly higher savings and foreign exchange reserves than Japan and Korea. | Kevin P.Gallagher Amos Irwin | 2014 | China & World Economy2014，22，6： | 5 |
| 14 | 国际绝经协会(IMS)关于绝经后激素治疗的最新建议显示文摘 | Amos Pines David W.Sturdee Martin H.Birkhuser Hermann P.G.Schneider Marco Gambacciani Nick Panay 孙爱军 王瑾晖 | 2007 | 生殖医学杂志2007，16，6： | 4 |
| 15 | Preference and belief: Ambiguity and competence in choice under uncertainty显示文摘 | Chip Heath Amos Tversky | 1991 | Journal of Risk and Uncertainty1991，，1： | 3 |
| 16 | 平板式光生物反应器的Parietochloris incisa超高密度培养显示文摘利用平板式光生物反应器对一种新分离的微藻Parietochlorisincisa进行了室外放大培养研究。在最适培养条件下 ,实现了对该微藻的超高密度培养 ,使单位培养体积和单位培养面积的细胞生物量分别达到了 7.35g/ (L·d)和 96 .12 g/ (m2 ·d) | 王长海 Amos Richmond | 2000 | 烟台大学学报(自然科学与工程版)2000，13，3： | 3 |
| 17 | Human parvovirus B19-associated hematopathy in HIV disease:need for clinicopathological revisit显示文摘Persons living with HIV infection occasionally suffer from anemia due to varying causes.These include the use of zidovudine,malnutrition especially vitamin B12and iron deficiency,opportunistic infections by Mycobacterium tuberculosis,Pneumocystis jiroveci,and direct hematological effects of HIV infection itself within the marrow microenvironment.Persistent Parvovirus B19(B19V)infection is a clinically important and treatable etiology of anemia in HIV-infected persons.B19V is known to show singular tropism and | Idris Abdullahi Nasir Jessy Thomas Medugu Amos Dangana | 2018 | The Journal of Biomedical Research2018，32，1： | 3 |
| 18 | 更年期医学:欧洲男女更年期协会2004/2005关于围绝经期和绝经后激素补充治疗的立场声明显示文摘目前从大量的随机对照临床试验(RCT)中已得出结论性的证据:对于经历令人痛苦的更年期症状的围绝经期和绝经后妇女,任何形式的全身HRT均可以缓解症状,没有其它治疗手段能产生相似效果。尽管这种证据与日俱增,但如何提供最好的临床医疗以减轻绝经症状和预防较远期的绝经后退化性疾病,仍在争论之中。当提供更年期医药时,HRT的剂量和方案的个体化是基于与症状的严重程度和绝经时间相关的最低有效剂量的原则。然而,在有症状的妇女中,尚没有多少关于长期应用不同HRT方案的资料,同时赖以说明心血管疾病、乳腺癌和骨质疏松症的基线风险的影响。在大多数病例中,个体化的处方联同生活方式的调整就可能对更年期症状、生活质量、性问题和骨质疏松症产生最终有益的作用,罕见严重副反应。基于最近的流行病学研究,不少是来自WHI中单用雌激素组的结果,欧洲男女更年期协会(EMAS)支持在有症状的妇女中进行新的HRT方案的研究,以提高临床中受益和风险之间的平衡,包括生活质量方面特有的信息;并解释美国和欧洲之间在治疗模式上的传统差异,以及在BMI、生活方式和饮食习惯方面的不同所产生的影响。对于早绝经(<45岁)的妇女,现有的资料支持HRT所特有的总体益处。目前,具有骨质疏松性骨折高危险性的妇女可考虑应用较长期的全身HRT,尤其是当其它治疗措施既不恰当又疗效不佳时,因为此时收益大于风险。而对于泌尿生殖道症状,已认为长期的局部雌激素治疗可能安全和有效。 | Sven O.Skouby Farook Al-Azzawi David Barlow Joaquin Calaf-Alsina Erdogan Ert ungealp Anne Gompel Alessandra Graziottin Decebal Hudita Amos ines Serge Rozenberg Gran Samsioe John C.Stevenson 陈瑛 | 2005 | 国外医学(妇幼保健分册)2005，16，5： | 3 |
| 19 | Maximum standardized uptake value on PET/CT in preoperative assessment of lymph node metastasis from thoracic esophageal squamous cell carcinoma显示文摘The presence of lymph node metastasis is an important prognostic factor for patients with esophageal cancer.Accurate assessment of lymph nodes in thoracic esophageal carcinoma is essential for selecting appropriate treatment and forecasting disease progression.Positron emission tomography combined with computed tomography(PET/CT)is becoming an important tool in the workup of esophageal carcinoma.Here,we evaluated the effectiveness of the maximum standardized uptake value(SUVmax)in assessing lymph node metastasis in esophageal squamous cell carcinoma(ESCC)prior to surgery.Fifty-nine surgical patients with pathologically confirmed thoracic ESCC were retrospectively studied.These patients underwent radical esophagectomy with pathologic evaluation of lymph nodes.They all had18F-FDG PET/CT scans in their preoperative staging procedures.None had a prior history of cancer.The pathologic status and PET/CT SUVmax of lymph nodes were collected to calculate the receiver operating characteristic(ROC)curve and to determine the best cutoff value of the PET/CT SUVmax to distinguish benign from malignant lymph nodes.Lymph node data from 27 others were used for the validation.A total of 323 lymph nodes including 39 metastatic lymph nodes were evaluated in the training cohort,and 117lymph nodes including 32 metastatic lymph nodes were evaluated in the validation cohort.The cutoff point of the SUVmax for lymph nodes was 4.1,as calculated by ROC curve(sensitivity,80%;specificity,92%;accuracy,90%).When this cutoff value was applied to the validation cohort,a sensitivity,a specificity,and an accuracy of 81%,88%,and 86%,respectively,were obtained.These results suggest that the SUVmax of lymph nodes predicts malignancy.Indeed,when an SUVmax of 4.1 was used instead of 2.5,FDG-PET/CT was more accurate in assessing nodal metastasis. | Amos JM Ela Bella Ya-Rui Zhang Wei Fan Kong-Jia Luo Tie-Hua Rong Peng Lin Hong Yang Jian-Hua Fu | 2014 | Chinese Journal of Cancer2014，33，4： | 3 |
| 20 | Caspase-3 expression in metastatic lymph nodes of esophageal squamous cell carcinoma is prognostic of survival显示文摘AIM:To assess whether differential expression of caspase-3 in paired metastatic lymph nodes(LNs)is prognostic of survival in patients with resectable esophageal squamous cell carcinoma(ESCC).METHODS:Capases-3 expression was evaluated immunohistochemically in 122 pairs of primary ESCCs and regional metastatic LNs assembled on tissue microarrays.The impact of caspase-3 expression on survival outcomes was analyzed by the Kaplan-Meier method and Cox proportional hazards regression model.RESULTS:The level of caspase-3 expression was significantly higher in LN metastases than in primary tumors(P<0.001).Caspase-3 expression in the primary tumors was associated with longer median survival(23 mo vs21 mo,P=0.033),whereas higher expression in paired metastatic LNs was associated with shorter median survival(20 mo vs 22 mo,P=0.043).Multivariate analysis showed that both were independent prognostic factors.CONCLUSION:Caspase-3 expression in metastatic LNs may be a potential independent predictor of poorer overall survival in patients with resected ESCC and LN metastasis.Protein expression in metastatic tumors may be a biomarker prognostic of survival. | Xiu-Shen Wang Kong-Jia Luo Amos Ela Bella Shan-Shan Bu Jing Wen Shui-Shen Zhang Yi Hu | 2014 | World Journal of Gastroenterology2014，20，15： | 2 |
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