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| 1 | 面向21世纪的卒中新定义:美国心脏病学会和美国卒中学会声明显示文摘尽管脑血管病有着全球性影响且对其病理生理学的认识有了很多进步,但是'卒中'这一术语在临床实践、临床研究或公共卫生评估中的定义却不一致。传统的定义依据于临床,却没有考虑到科学技术的进步。美国心脏协会(AHA)和美国卒中协会(ASA)卒中分会组织了写作小组,为21世纪卒中新定义撰写专家共识性声明。中枢神经系统(CNS)梗死,指由缺血所导致的脑、脊髓或视网膜的细胞死亡,是基于持续性损害的神经病理学、神经影像学和(或)临床证据。CNS梗死表现为一个临床谱:缺血性卒中特指伴有明显症状的CNS梗死,而静息性梗死根据定义指未引起已知的症状的梗死。卒中也还包括脑出血和蛛网膜下腔出血。新定义的卒中结合了临床和组织学标准,可被用于实践、研究和公共卫生评估。 | 俞羚 董荃 宋叶平 江静雯 李卉 刘亮贤 苏爱萍 李焰生 Sacco RL Kasner SE Broderick JP Caplan LR Connors JJ Culebras A Elkind MS George MG Hamdan AD Higashida RT Hoh BL Janis LS Kase CS Kleindorfer DO Lee JM Moseley ME Peterson ED Turan TN Valderrama AL Vinters HV | 2013 | 神经病学与神经康复学杂志2013，10，2： | 188 |
| 2 | IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treat- ment of Cancer Brain Tumor Group显示文摘 | van den Bent M J Dubbink HJ Marie Y Brandes AA Taphoorn MJ Wesseling P Frenay M Tijssen CC Lacombe D ldbaih A van Marion R Kros JM Dinjens WN Gorlia T. Sanson M. | 2010 | 中国神经肿瘤杂志2010，8，1： | 22 |
| 3 | 在没有危险因素的情况下,正常的低密度脂蛋白胆固醇水平与亚临床动脉粥样硬化相关显示文摘普遍认为缺乏心血管病危险因素(cardiovascular risk factors,CVRF)人群的动脉粥样硬化发生风险低,然而,无CVRF的个体仍然有心血管事件发生。为了确定无CVRF个体中亚临床动脉粥样硬化的预测因子, | Fernández-Friera L Fuster V López-Melgar B Oliva B García-Ruiz JM Mendiguren J Bueno H Pocock S Ibánez B Fernández-Ortiz A Sanz J 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，12： | 17 |
| 4 | Intraoperative cell salvage with autologous transfusion in liver transplantation显示文摘Liver transplant(LT) is the primary treatment for patients with end-stage liver disease. About 25000 LTs are performed annually in the world. The potential for intraoperative bleeding is quite variable. However, massive bleeding is common and requires blood transfusion. Allogeneic blood transfusion has an immunosuppressive effect and an impact on recipient survival, in addition to the risk of transmission of viral infections and transfusion errors, among others.Techniques to prevent excessive bleeding or to use autologous blood have been proposed to minimize the negative effects of allogeneic blood transfusion.Intraoperative reinfusion of autologous blood is possible through previous selfdonation or blood collected during the operation. However, LT does not normally allow autologous transfusion by prior self-donation. Hence, using autologous blood collected intraoperatively is the most feasible option. The use of intraoperative blood salvage autotransfusion(IBSA) minimizes the perioperative use of allogeneic blood, preventing negative transfusion effects without negatively impacting other clinical outcomes. The use of IBSA in patients with cancer is still a matter of debate due to the theoretical risk of reinfusion of tumor cells. However, studies have demonstrated the safety of IBSA in several surgical procedures, including LT for hepatocellular carcinoma. Considering the literature available to date, we can state that IBSA should be routinely used in LT, both in patients with cancer and in patients with benign diseases. | Marcelo A Pinto Marcio F Chedid Leo Sekine Andre P Schmidt Rodrigo P Capra Carolina Prediger Jo?o E Prediger Tomaz JM Grezzana-Filho Cleber RP Kruel | 2019 | World Journal of Gastrointestinal Surgery2019，11，1： | 16 |
| 5 | Wireless capsule endoscopy显示文摘Wireless capsule endoscopy is a new technique that allows complete exploration of the small bowel without external wires. Its role has been analyzed in many small bowel diseases such as obscure gastrointestinal bleeding, Crohn's disease and gastrointestinal polyposis syndromes with promising results. Studies on other pathologies (i.e. small bowel tumour, celiac disease) are under evaluation to define the role of this technique. | A Mata J Llach JM Bordas | 2008 | World Journal of Gastroenterology2008，14，13： | 12 |
| 6 | 男性迟发性性腺功能减退症的检查、治疗和监测:国际男科学会(ISA)、国际老年男性研究会(ISSAM)、欧洲泌尿外科学会(EAU)、欧洲泌尿外科学院(EAA)和美国男科学会(ASA)联合推荐显示文摘简介
人口学资料明确显示:老年人口占总人口的百分率正逐年增加。当前,有关老年男性雄激素缺乏的问题逐渐成为令人感兴趣、但又充满争议的世界性话题。已经有横向和纵向的研究资料表明,随着年龄增大,成年男子的雄激素水平逐渐降低, | Wang C Nieschlage E Swerdloff R Behre HM Hellstrom WJ Gooren LJ Kaufman JM Legros JJ Lunenfeld B Morales A Morley JE Schulman C Thompson IM Weidner W Wu FCW 伍学焱(翻译) | 2011 | 国际生殖健康/计划生育杂志2011，30，1： | 8 |
| 7 | Lack of Efficacy of Bevacizumab Plus Irinotecan in Children with Recurrent Malignant Glioma and Diffuse Brainstem Glioma:A Pediatric Brain Tumor Consortium Study显示文摘PURPOSE:A phase Ⅱ study of bevacizumab(BVZ) plus irinotecan(CPT-11) was conducted in children with recurrent malignant glioma(MG) and intrinsic brainstem glioma(BSG).PATIENTS AND METHODS:Eligible patients received two doses of BVZ | Gururangan S Chi SN Young Poussaint T Onar-Thomas A Gilbertson RJ Vajapeyam S Friedman HS Packer RJ Rood BN Boyett JM Kun LE | 2010 | 中国神经肿瘤杂志2010，8，2： | 7 |
| 8 | 婴儿主导早产儿喂养方式显示文摘近年来,婴儿主导喂养方式(infant driven feeding,IDF)被广泛应用,但其临床获益研究较少,本研究以早产儿为观察对象,分析IDF是否较传统的医生主导喂养方式(practitioner driven feeding,PDF)有优势。IDF是按照较客观的评分表实施喂养,通过反映早产儿觉醒度及活动能力的"准备程度评分"决定是否经口喂养; | 周颖 冯琪 Wellington A Perlman JM | 2016 | 中国新生儿科杂志2016，31，6： | 5 |
| 9 | Gallbladder tuberculosis: False-positive PET diagnosis of gallbladder cancer显示文摘Gallbladder tuberculosis (GT) is an extremely rare disease, and very few cases have been reported in the literature. The first case of GT was described in 1870 by Gaucher. A correct preoperative diagnosis of GT is unusual, and it is frequently confused with various gallbladder diseases. We present a new case of a patient who underwent surgery with the preoperative diagnosis of gallbladder cancer after a false positive positron emission tomography scan in the diagnostic work-up. | JM Ramia K Muffak A Fernández J Villar D Garrote JA Ferron | 2006 | World Journal of Gastroenterology2006，12，40： | 5 |
| 10 | 急性儿茶酚胺暴露引起可逆的无心脏细胞再生的心肌细胞损伤显示文摘儿茶酚胺增加心脏收缩力,但暴露于高浓度儿茶酚胺或长时间暴露可引起心脏损伤。最近的一项研究表明,小鼠单次皮下注射异丙肾上腺素(isoproterenol,ISO;200 mg/kg)导致急性心肌细胞死亡(8%-10%),但在1个月之内心脏完整修复。心脏再生是通过内源性原癌基因蛋白质cKit+心脏干细胞介导新的心肌细胞形成。 | 刘莉 叶鹏 Wallner M Duran JM Mohsin S Troupes CD Vanhoutte D Borghetti G Vagnozzi RJ Gross P Yu D Trappanese DM Kubo H Toib A Sharp TE Harper SC Volkert MA Starosta T Feldsott EA Berretta RM Wang T Barbe MF Molkentin JD Houser SR | 2016 | 中华高血压杂志2016，24，8： | 4 |
| 11 | 凝血酶受体活化与血小板膜糖蛋白Ⅰ bα的异位分布机制显示文摘目的 检测凝血酶受体活化过程中血小板膜糖蛋白 (GP)Ⅰbα的动态分布及其细胞骨架蛋白的改变,揭示GPⅠbα的异位分布机制与凝血酶受体在血小板信号传递中的作用。方法 以凝血酶受体活化肽 (thrombinreceptoractivatingpeptide,TRAP)诱导血小板活化,应用流式细胞术比较刺激前后血小板膜表面GPⅠbα及P 选择素的表达,并通过转移电泳及免疫沉淀技术,分析细胞骨架中GPⅠbα、肌动蛋白、肌球蛋白的变化。观测细胞松弛素 (Cytochalasin) D与腺苷三磷酸双磷酸酶(Apyrase)Ⅶ对血小板活化过程的影响。结果 TRAP作用后促使血小板活化,流式细胞术检测结果显示其P 选择素水平显著升高,而GPⅠbα先呈现进行性减少,而后逐渐回升的可逆性变化。抑制剂作用后这一过程受到不同程度影响,其中细胞松弛素D能阻滞GPⅠbα的内移, ApyraseⅦ对活化过程中GPⅠbα的逆转没有影响,只对它的恢复起作用,促使GPⅠbα迅速返回细胞表面。细胞骨架蛋白分析结果也表明肌动蛋白、肌球蛋白与GPⅠbα受刺激后呈先增加后减少的动态变化趋势。细胞松弛素D能阻滞GPⅠbα、肌动蛋白与肌球蛋白向骨架中心的转位, ApyraseⅦ则能加快骨架蛋白在骨架中心的消散。免疫印迹证实GPⅠbα的这种可逆性变化与血小板膜骨架紧密相关。 | 韩悦 JM Pasquet A Nurden 王兆钺 阮长耿 | 2005 | 中华血液学杂志2005，26，3： | 3 |
| 12 | 稳定性冠状动脉疾病患者的尿11-脱氢血栓素B_2与死亡率的关系显示文摘已有研究证明,应用阿司匹林抗血小板治疗可减少冠状动脉疾病(coronary artery disease,CAD)患者的不良预后。阿司匹林不可逆地抑制血小板环加氧酶1(cyclooxygenase-1,COX-1)并减弱血栓烷A2(thromboxane A2,TXA2)介导的血小板聚集, | 刘莉 叶鹏 McCullough PA Vasudevan A Sathyamoorthy M Schussler JM Velasco CE Lopez LR Swift C Peterson M Bennett-Firmin J Schiffmann R Bottiglieri T | 2017 | 中华高血压杂志2017，25，1： | 3 |
| 13 | Resection of a rapid-growing 40-cm giant liver hemangioma显示文摘Hemangiomas are the most frequent benign tumors of the liver. Most hemangiomas are asymptomatic and therefore largely diagnosed only in routine screening tests. Usually they are small and require no specific treatment. In some situations they can reach great dimensions, causing some discomfort to the patient. Resection of liver hemangioma is indicated in cases of great dimension tumors causing symptoms such as pain, nausea or bloating caused by compression of adjacent organs. We report a case of a rare giant hemangioma with rapid growth in short time:a 50 year old female reported to our institution with a 40 cm giant liver hemangioma and then underwent a left hepatectomy. | Andreas JM Koszka Fabio G Ferreira Caio GG de Aquino Maurício A Ribeiro André S Gallo Elisa MC Aranzana Luiz A Szutan | 2010 | World Journal of Hepatology2010，2，7： | 3 |
| 14 | 膝骨关节炎的家庭训练显示文摘膝骨关节炎的家庭训练膝骨关节炎是造成骨骼肌肉伤残的一个主要原因。治疗的目的包括减轻疼痛和提高功能。大量研究表明,家庭训练可以有效提高膝骨关节炎患者的肌力,减轻疼痛,提高功能。这篇系统评价和meta分析的目的在于阐明家庭训练项目对于这个疾病治疗的有效性。这篇综述纳入了对膝骨关节炎患者实施家庭训练项目和住院或非住院物理治疗的比较的实验。兴趣指标是疼痛和功能。通过系统回顾,16篇研究纳入进来。家庭训练项目的干预包括开链和闭链运动。 | Anwer S Alghadir A Brismée JM 何成奇 | 2017 | 中国康复2017，32，1： | 2 |
| 15 | Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischemic limb显示文摘 | Isner JM Pieczek A Schainfeld R | | 0，，： | 2 |
| 16 | 外科减肥手术后高血压缓解和复发的预测因素显示文摘目前,只有很少量研究涉及外科减肥手术后高血压得到缓解和复发的影响因素,没有可用于预测高血压复发相关因素的信息。该研究的目的是评估在外科减肥手术后第1年和第3年里高血压的缓解情况和复发率,并寻找可能的预测因素。 | Benaiges D Sagué M Flores-Le Roux JA Pedro-Botet J Ramón JM Villatoro M Chillarón JJ Pera M Más A Grande L Goday A 陈云 | 2016 | 中华高血压杂志2016，24，9： | 2 |
| 17 | 体位性低血压和心脑血管疾病风险、认知功能下降、跌倒及全因死亡率之间的关系显示文摘许多研究结果表明,体位性低血压(orthostatic hypotension,OH)可能是心脑血管风险和全因死亡率的独立预测因子,尤其是在老年人群。1996年的共识将OH统一定义为站立3 min内收缩压下降≥20mm Hg(1mm Hg=0.133kPa)和(或)舒张压下降≥10mm Hg。方法: | Angelousi A Girerd N Benetos A Frimat L Gautier S Weryha G Boivin JM 刘莉 叶鹏 | 2014 | 中华高血压杂志2014，22，8： | 2 |
| 18 | 胱氨酸结石的经皮手术和体外震波治疗显示文摘报道经皮肾镜取石及体外震波碎石治疗9例胱氨酸结石。仅经皮肾镜取石的6次住院中,5次成功,1次有残留结石;仅作体外震波碎石的13次住院中,结石完全破碎5次,部分破碎5次,未破碎3次;两者合并应用的4次住院中先行经皮肾镜取石或体外震波碎石各2次。并对此种结石不易粉碎的原因和治疗成功的因素等进行了讨论。 | 何家扬 Martin X Gelet A Dubernard JM | 1990 | 临床泌尿外科杂志1990，5，2： | 2 |
| 19 | Aging and Parkinson's disease:Substantia nigra regional selectivity显示文摘 | Fearnley JM Lees A | 1991 | Brain1991，114，5： | 2 |
| 20 | 老年女性蔬菜硝酸盐的摄入与颈动脉粥样硬化和缺血性脑血管病的相关性显示文摘膳食硝酸盐的短期增加可通过形成一氧化氮和其他氮氧化物来改善血管健康。其是否可降低长期血管疾病风险尚未得到验证,为了明确这一点,Bondonno教授团队调查了植物来源的硝酸盐摄入与老年女性颈总动脉内膜中层厚度(common carotid artery intimamedia thickness,CCA-IMT)、斑块严重程度和缺血性脑血管疾病事件的关系(n=1226),方法:纳入研究对象,确定基线时(1998年)的蔬菜硝酸盐摄入量、生活方式因素和心血管病危险因素。 | 刘莉 叶鹏 Bondonno CP Blekkenhorst LC Prince RL Ivey KL Lewis JR Devine A Woodman RJ Lundberg JO Croft KD Thompson PL Hodgson JM | 2017 | 中华高血压杂志2017，25，9： | 2 |
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