|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | G2A is an oncogenic G protein-coupled receptor显示文摘 | Zohn I E Klinger M Karp X | 2000 | Oncogene2000，19，34： | 1 |
| 2 | The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroport- in disease显示文摘 | Zohn IE De Domenico I Pollock A | 2007 | Blood2007，109，10： | 1 |
| 3 | Chronic exposure to high-density polyethylene microplastic through feeding alters the nutrient metabolism of juvenile yellow perch (Perca flavescens)显示文摘Microplastics are emergent contaminants threatening aquatic organisms including aquacultured fish.This study investigated the effects of high-density polyethylene(HDPE,100 to 125 mm)on yellow perch(Perca flavescens)based on integrative evaluation including growth performance,nutritional status,nutrient metabolism,fish health,and gut microbial community.Five test diets(0,1,2,4,or 8 g HDPE/100 g diet)containing 41%protein and 10.5%lipid were fed to juvenile perch(average body weight,25.9±0.2 g;n=15)at a feeding rate of 1.5%to 2.0%body weight daily.The feeding trial was conducted in a flow-through water system for 9 wk with 3 tanks per treatment and 15 yellow perch per tank.No mortality or HDPE accumulation in the fish was found in any treatments.Weight gain and condition factor of fish were not significantly impacted by HDPE(P>0.05).Compared to the control group,fish fed the 8%HDPE diet had significantly decreased levels of protein and ash(P<0.05).In response to the increasing levels of HDPE exposure,the hepatosomatic index value,hepatocyte size,and liver glycogen level were increased,but lipid content was reduced in the liver tissues.Compared to the control treatment,fish fed the 8%HDPE diet had significant accumulations of total bile acids and different metabolism pathways such as bile acid biosynthesis,pyruvate metabolism,and carnitine synthesis.Significant enterocyte necrosis was documented in the foregut of fish fed the 2%or 8%HDPE diet;and significant cell sloughing was observed in the midgut and hindgut of fish fed the 8%HDPE diet.Fish fed the 2%HDPE diet harbored different microbiota communities compared to the control fish.This study demonstrates that HDPE ranging from 100 to 125 mm in feed can be evacuated by yellow perch with no impact on growth.However,dietary exposure to HDPE decreased whole fish nutrition quality,altered nutrient metabolism and the intestinal histopathology as well as microbiota community of yellow perch.The results indicate that extended exposure may pose a risk to fish health and jeopardize the nutrition quality of aquacultured end product.This hypothesis remains to be investigated further. | Xing Lu Dong-Fang Deng Fei Huang Fabio Casu Emma Kraco Ryan J.Newton Merry Zohn Swee J.Teh Aaron M.Watson Brian Shepherd Ying Ma Mahmound A.O.Dawood Lorena M.Rios Mendoza | 2022 | Animal Nutrition2022，，2： | 1 |
| 4 | G2A is an oncogenic G protein-coupled receptor 显示文摘 | Zohn IE Klinger M Karp X | 2000 | Oncogene2000，19，： | 1 |
| 5 | Rho GTPase-dependent transformation by G protein coupled receptors 显示文摘 | Whitehead I P Zohn IE Der CJ | 2001 | Onco- gene2001，20，： | 1 |
| 6 | p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation显示文摘 | Zohn IE Li Y Skolnik EY | 2006 | Ce112006，125，5： | 1 |
| 7 | Rho family proteins and Ras transformation:the RHOad less traveled gets congested显示文摘 | Zohn IM Campbell SL Khosravi-Far | 1998 | Oncogene1998，17，11： | 1 |
| 8 | C2A is an oneogenic G-protein -coupled receptor显示文摘 | ZOHN I E KLINGER M KARP X | 2000 | Oncogene2000，19，： | 1 |
| 9 | G2A is an oncogenie G protein-coupled receptor显示文摘 | Zohn I E Klinger M Karp X | 2000 | Oneogene2000，19，34： | 1 |
| 10 | The visceral yolk sac endoderm provides for absorption of nutrients to the embryo during neurulation显示文摘 | Zohn IE Sarkar AA | 2010 | Birth Defects Res A Clin Mol Teratol2010，88，8： | 1 |
| 11 | G2A is an oncogenic G protein-coupled receptor 显示文摘 | Zohn IE Klinger M Karp X | 2000 | Oncogene2000，19，： | 1 |
| 12 | p38 and a p38- interacting protein are critical for downregulation of E- cadherin during mouse gastrulation显示文摘 | ZOHN IE LI YQ SKOLNIK EY | 2006 | Cell2006，125，5： | 1 |
| 13 | The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation显示文摘 | Becker-Heck A Zohn IE Okabe N | | 0，，1： | 1 |
| 14 | G2A is an oncogenic G protein-coupled receptor 显示文摘 | Zohn IE Klinger M Karp X | 2000 | Oncogene2000，19，： | 1 |
| 15 | p38 and a p38-interaeting protein are critical for downregulation of E-cadherin during mouse gastrulation 显示文摘 | Zohn IE Li Y Skolnik EY | 2006 | Cell2006，125，5： | 1 |
| 16 | p38 and a p38-interacting protein are critical for downregulation of E-eadherin during mouse gastrulation显示文摘 | Zohn IE Li Y Skolnik EY | 2006 | Cell2006，125，5： | 1 |
| 17 | The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation显示文摘 | Becker-Heck A Zohn IE Okabe N | 2011 | Nat Genet2011，43，1： | 1 |
| 18 | 查看详情显示文摘 | Zohn E Wiebusche K | | 0，，： | 1 |
| 19 | The coiled-coil domain containing protein CCDC40is essential for motile cilia function and left-right axis formation显示文摘 | Becker-Heck A Zohn IE Okabe N | 2011 | Nat Genet2011，43，： | 1 |
| 20 | Rho family proteins and Ras transformation: the RHOad less traveled gets congested 显示文摘 | ZOHN I M CAMPBELL S L KHOSRAVI-FAR R | 1998 | Oncogene1998，17，11： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员