维普中文期刊产品整合服务
37篇 您的检索式:作者名="Zepeng Zhang"
    题名 作者 年代 出处 被引量
1Traditional Chinese Medicine in the prevention and treatment of stable angina pectoris in patients with coronary heart disease based on the theory of 'phlegm and blood stasis' under guidance of evidence-based medicine:a prospective cohort study显示文摘OBJECTIVE: To ascertain whether continuous treatment with Traditional Chinese Medicine(TCM) combined with standardized drug therapy from Western Medicine can further reduce the incidence of cardiovascular events in patients with coronary heart disease and angina and reduce the incidence of angina pectoris in patients with coronary heart disease.METHODS: A multicenter, prospective cohort study of 1042 patients in 22 hospitals was conducted. A total of 423 patients with angina pectoris were treated with standardized Western Medicine alone(control group) and 619 with a combination of Chinese and Western Medicine(exposure group). The two groups underwent follow-up for 1 year to establish whether there was any improvement in the incidence of cardiovascular events or change in the curative effect.RESULTS: The incidence of primary endpoint events in the combined-exposure group decreased by 0.45%(P > 0.05) and the incidence of secondary terminal events decreased by 5.25% in comparison with the control group(P < 0.05). The total angina pectoris score clearly decreased in the Western Medicine group over the first 6 months, but the decline was more apparent in the combined-exposure group.CONCLUSION: Compared with treatment using standardized Western Medicine alone, providing TCM combined with Western medical treatment reduced the incidence of cardiovascular events in patients with stable angina pectoris(grade Ⅱ endpoint) and effectively improved the curative effect.CHEN Ying XIAO Xue XU Xiaolin DENG Yue ZHANG Zepeng 2021Journal of Traditional Chinese Medicine2021,41,1:19
2Spatial correlation-based characterization of acoustic emission signal-cloud in a granite sample by a cube clustering approach显示文摘To extract more in-depth information of acoustic emission(AE)signal-cloud in rock failure under triaxial compression,the spatial correlation of scattering AE events in a granite sample is effectively described by the cube-cluster model.First,the complete connection of the fracture network is regarded as a critical state.Then,according to the Hoshen-Kopelman(HK)algorithm,the real-time estimation of fracture con-nection is effectively made and a dichotomy between cube size and pore fraction is suggested to solve such a challenge of the one-to-one match between complete connection and cluster size.After,the 3D cube clusters are decomposed into orthogonal layer clusters,which are then transformed into the ellip-soid models.Correspondingly,the anisotropy evolution of fracture network could be visualized by three orthogonal ellipsoids and quantitatively described by aspect ratio.Besides,the other three quantities of centroid axis length,porosity,and fracture angle are analyzed to evaluate the evolution of cube cluster.The result shows the sample dilatancy is strongly correlated to four quantities of aspect ratio,centroid axis length,and porosity as well as fracture angle.Besides,the cube cluster model shows a potential pos-sibility to predict the evolution of fracture angle.So,the cube cluster model provides an in-depth view of spatial correlation to describe the AE signal-cloud.Dongjie Xue Zepeng Zhang Cheng Chen Jie Zhou Lan Lu Xiaotong Sun Yintong Liu 2021International Journal of Mining Science and Technology2021,31,4:5
3Using thermodynamic parameters to study self-healing and interface properties of crumb rubber modified asphalt based on molecular dynamics simulation显示文摘The thermodynamic property of asphalt binder is changed by the addition of crumb rubber,which in turn influences the self-healing property as well as the cohesion and adhesion within the asphalt-aggregate system.This study investigated the self-healing and interface properties of crumb rubber modified asphalt(CRMA)using thermodynamic parameters based on the molecular simulation approach.The molecular models of CRMA were built with representative structures of the virgin asphalt and the crumb rubber.The aggregate was represented by SiO2 and Al2O3 crystals.The selfhealing capability was evaluated with the thermodynamic parameter wetting time,work of cohesion and diffusivity.The interface properties were evaluated by characterizing the adhesion capability,the debonding potential and the moisture susceptibility of the asphalt-aggregate interface.The self-healing capability of CRMA is found to decrease as the rubber content increases.The asphalt-Al2O3 interface with higher rubber content has stronger adhesion and moisture stability.But the influence of crumb rubber on the interfacial properties of asphalt-SiO2 interface has no statistical significance.Comparing with the interfacial properties of the asphalt-SiO2 interface,the asphalt-Al2O3 interface is found to have a stronger adhesion but a worse moisture susceptibility for its enormous thermodynamic potential for water to displace the asphalt binder.Dongliang HU Jianzhong PEI Rui LI Jiupeng ZHANG Yanshun JIA Zepeng FAN 2020Frontiers of Structural and Civil Engineering2020,14,1:5
4Instability characteristics of a co-rotating wingtip vortex pair based on bi-global linear stability analysis显示文摘The Stereo Particle Image Velocimetry(SPIV)technology is applied to measure the wingtip vortices generated by the up-down symmetrical split winglet.Then,the temporal biglobal Linear Stability Analysis(bi-global LSA)is performed on this nearly equal-strength corotating vortex pair,which is composed of an upper vortex(vortex-u)and a down vortex(vortex-d).The results show that the instability eigenvalue spectrum illustrated by(ωr,ω_(i))contains two types of branches:discrete branch and continuous branch.The discrete branch contains the primary branches of vortex-u and vortex-d,the secondary branch of vortex-d and coupled branch,of which all of the eigenvalues are located in the unstable half-plane ofω_(i)>0,indicating that the wingtip vortex pair is temporally unstable.By contrast,the eigenvalues of the continuous branch are concentrated on the half-plane ofω_(i)<0 and the perturbation modes correspond to the freestream perturbation.In the primary branches of vortex-u and vortex-d,Mode P_(u) and Mode Pd are the primary perturbation modes,which exhibit the structures enclosed with azimuthal wavenumber m and radial wavenumber n,respectively.Besides,the results of stability curves for vortex-u and vortex-d demonstrate that the instability growth rates of vortex-u are larger than those of vortex-d,and the perturbation energy of Mode P_(u) is also larger than that of Mode Pd.Moreover,the perturbation energy of Mode P_(u) is up to 0.02650 and accounts for 33.56%percent in the corresponding branch,thereby indicating that the instability development of wingtip vortex is dominated by Mode P_(u).By further investigating the topological structures of Mode P_(u) and Mode Pd with streamwise wavenumbers,the most unstable perturbation mode with a large azimuthal wavenumber of m=5-6 is identified,which imposes on the entire core region of vortex-u.This large azimuthal wavenumber perturbation mode can suggest the potential physical-based flow control strategy by manipulating it.Zepeng CHENG Siyi QIU Yang XIANG Chun SHAO Miao ZHANG Hong LIU 2021Chinese Journal of Aeronautics2021,34,5:4
5Ultracompact dual-mode waveguide crossing based on subwavelength multimode-interference couplers显示文摘We propose and experimentally demonstrate a novel ultracompact dual-mode waveguide crossing based on subwavelength multimode-interference couplers for a densely integrated on-chip mode-division multiplexing system.By engineering the lateral-cladding material index and manipulating phase profiles of light at the nanoscale using an improved inverse design method, a subwavelength structure could theoretically realize the identical beat length for both TE_0 and TE1, which can reduce the scale of the device greatly. The fabricated device occupied a footprint of only 4.8 μm× 4.8 μm. The measured insertion losses and crosstalks were less than 0.6 d B and-24 d B from 1530 nm to 1590 nm for both TE0 and TE1 modes, respectively. Furthermore, our scheme could also be expandedto design waveguide crossings that support more modes.WEIJIE CHANG LULUZI LU XINSHU REN DONGYU LI ZEPENG PAN MENGFAN CHENG DEMING LIU MINMING ZHANG 2018Photonics Research2018,6,7:4
6High phosphate removal using La(OH)3 loaded chitosan based composites and mechanistic study显示文摘Our present study was to prepare a biomass-supported adsorbents with high adsorptive capacity and high selectivity to prevent the accelerated eutrophication in water body.To this end,different metal hydroxide(La,Zr and Fe)first was successfully loaded on chitosan microspheres.Then the quaternary ammonium group with different content was introduced into the adsorbent by polymerization.By comparison of adsorption properties,chitosanLa(OH)3-quaternary ammonium-20%(CS-La-N-20%)has strong adsorption to phosphate(160 mg/g)by immobilizing nano-sized La(OH)3 within a quaternary-aminated chitosan and it maintain high adsorption in the presence of salt ions.The pH results indicated that the CS-La-N-20%would effectively sequestrate phosphate over a wide pH range between 3 and 7 without significant La3+leaching.What’s more,adsorption capacity on the introduce of positively charged quanternary-aminated groups was significantly higher than that of the unmodified adsorbents at alkaline conditions.The column adsorption capacity reached 1300 bed volumes(BV)when phosphate concentration decreased until 0.5 mg/L at 6 BV/hr.The column adsorption/desorption reveals that no significant capacity loss is observed,indicating excellent stability and repeated use property.Characterizations revealed that phosphate adsorption on CS-La-N-20%through ligand exchange(impregnated nano-La(OH)3)and electrostatic attraction(positively charged quanternary-aminated groups).All the results suggested that CS-La-N-20%can serve as a promising adsorbent for preferable phosphate removal in realistic application.Shaopeng Zhang Yi Zhang Jie Ding Zepeng Zhang Chao Gao Muslim Halimi Hary Demey Zhen Yang Weiben Yang 2021Journal of Environmental Sciences2021,33,8:3
7Stretchable,Rehealable,Recyclable,and Reconfigurable Integrated Strain Sensor for Joint Motion and Respiration Monitoring显示文摘Cutting-edge technologies of stretchable,skin-mountable,and wearable electronics have attracted tremendous attention recently due to their very wide applications and promising performances.One direction of particular interest is to investigate novel properties in stretchable electronics by exploring multifunctional materials.Here,we report an integrated strain sensing system that is highly stretchable,rehealable,fully recyclable,and reconfigurable.This system consists of dynamic covalent thermoset polyimine as the moldable substrate and encapsulation,eutectic liquid metal alloy as the strain sensing unit and interconnects,and off-the-shelf chip components for measuring and magnifying functions.The device can be attached on different parts of the human body for accurately monitoring joint motion and respiration.Such a strain sensing system provides a reliable,economical,and ecofriendly solution to wearable technologies,with wide applications in health care,prosthetics,robotics,and biomedical devices.Chuanqian Shi Zhanan Zou Zepeng Lei Pengcheng Zhu Guohua Nie Wei Zhang Jianliang Xiao 2021Research2021,,1:3
8On Correlation Properties of Boolean Functions显示文摘ZHUO Zepeng ZHANG Weiguo GAO Sheng XIAO Guozhen 2011Chinese Journal of Electronics2011,20,1:3
9Inhibition of p53 and/or AKT as a new therapeutic approach specifically targeting ALT cancers显示文摘While the majority of all human cancers court teract telomere shortening by expressing telomerase,-15%of all cancers maintain telomere length by a telomerase?independent mechanism known as alternative lengthening of telomeres(ALT).Here,we show that high load of intrinsic DNA damage is present in ALT cancer cells,leading to apoptosis stress by activating p53-independent,but JNK/c-IVIyc-dependent apoptotic pathway.Notably,ALT cells expressing wild-type p53 show much lower apoptosis than p53-deficient ALT cells.Mechanistically,we find that intrinsic DNA damage in ALT cells induces low level of p53 that is insufficient to initiate the transcription of apoptosis-related genes,but is sufficient to stimulate the expression of key components of mTORC2(mTOR and Rictor),which in turn leads to phosphorylation of AKT.Activated AKT(p-AKT)thereby stimulates downstream anti-apoptotic events.Therefore,p53 and AKT are the key factors that suppress sponta?neous apoptosis in ALT cells.Indeed,inhibition of p53 or AKT selectively induces rapid death of ALT cells in vitro,and p53 inhibitor severely suppresses the growth of ALT-cell xenograft tumors in mice.These findings reveal a previously unrecognized function of p53 in antiapoptosis and identify that the inhibition of p53 or AKT has a potential as therapeutics for specifically targeting ALT cancers.Yuanlong Ge Shu Wu Zepeng Zhang Xiaocui Li Feng Li Siyu Yan Haiying Liu Junjiu Huang Yong Zhao 2019Protein & Cell2019,10,11:2
10On-chip cyclic-AWG-based 12 × 12 silicon wavelength routing switches with minimized port-to-port insertion loss fluctuation显示文摘With the rapidly increasing bandwidth requirements of optical communication networks, compact and low-cost large-scale optical switches become necessary. Silicon photonics is a promising technology due to its small footprint, cost competitiveness, and high bandwidth density. In this paper, we demonstrate a 12 × 12 silicon wavelength routing switch employing cascaded arrayed waveguide gratings(AWGs) connected by a silicon waveguide interconnection network on a single chip. We optimize the connecting strategy of the crossing structure to reduce the switch's footprint. We develop an algorithm based on minimum standard deviation to minimize the port-toport insertion loss(IL) fluctuation of the switch globally. The simulated port-to-port IL fluctuation decreases by about 3 dB compared with that of the conventional one. The average measured port-to-port IL is 13.03 dB, with a standard deviation of 0.78 dB and a fluctuation of 2.39 dB. The device can be used for wide applications in core networks and data centers.ZEPENG PAN SONGNIAN FU LULUZI LU DONGYU LI WEIJIE CHANG DEMING LIU MINMING ZHANG 2018Photonics Research2018,6,5:2
11Ultrasound-assisted preparation and charaterization of anionic sufactant modified montmorillonites显示文摘Zhang Zepeng Liao Libing Xia Zhiguo 0,,04:1
12Structure-guided manipulation of the regioselectivity of the cyclosporine A hydroxylase CYP-sb21 from Sebekia benihana显示文摘The cytochrome P450 enzyme CYP-sb21 from the rare actinomycete Sebekia benihana is capable of hydroxylating the immunosuppressive drug molecule cyclosporine A(CsA)primarily at the 4th N-methyl leucine(MeLeu4),giving rise toγ-hydroxy-N-methyl-L-Leu4-CsA(CsA-4-OH).This oxidative modification of CsA leads to dramatically reduced immunosuppressive activity while retaining the hair growth-promoting side-effect,thus demonstrating great application potential in both pharmaceutical and cosmetic industries.However,this P450 enzyme also hydroxylates CsA at the unwanted position of the 9th N-methyl leucine(MeLeu9),indicating that the regioselectivity needs to be improved for the development of CsA-4-OH into a commercial hair growth stimulator.Herein,we report the crystal structure of CYP-sb21 in its substrate-free form at 1.85Å.Together with sequence and 3D structure comparisons,Autodock-based substrate docking,molecular dynamics(MD)simulation,and site-directed mutagenesis,we identified a number of key residues including R294,E264,and M179 that can improve catalytic efficiency or change the regioselectivity of CYP-sb21 towards CsA,setting the stage for better enzymatic preparation of CsA-4-OH.This study also provides new insights into the substrate recognition and binding mechanism of P450 enzymes that accommodate bulky substrates.Fengwei Li Li Ma Xingwang Zhang Jingfei Chen Feifei Qi Yinyue Huang Zepeng Qu Lishan Yao Wei Zhang Eung-Soo Kim Shengying Li 2020Synthetic and Systems Biotechnology2020,5,3:1
13Super enhancers targeting ZBTB16 in osteogenesis protect against osteoporosis显示文摘As the major cell precursors in osteogenesis, mesenchymal stem cells(MSCs) are indispensable for bone homeostasis and development. However, the primary mechanisms regulating osteogenic differentiation are controversial. Composed of multiple constituent enhancers, super enhancers(SEs) are powerful cis-regulatory elements that identify genes that ensure sequential differentiation. The present study demonstrated that SEs were indispensable for MSC osteogenesis and involved in osteoporosis development. Through integrated analysis, we identified the most common SE-targeted and osteoporosis-related osteogenic gene,ZBTB16. ZBTB16, positively regulated by SEs, promoted MSC osteogenesis but was expressed at lower levels in osteoporosis.Mechanistically, SEs recruited bromodomain containing 4(BRD4) at the site of ZBTB16, which then bound to RNA polymerase IIassociated protein 2(RPAP2) that transported RNA polymerase Ⅱ(POL Ⅱ) into the nucleus. The subsequent synergistic regulation of POL Ⅱ carboxyterminal domain(CTD) phosphorylation by BRD4 and RPAP2 initiated ZBTB16 transcriptional elongation, which facilitated MSC osteogenesis via the key osteogenic transcription factor SP7. Bone-targeting ZBTB16 overexpression had a therapeutic effect on the decreased bone density and remodeling capacity of Brd4^(fl/fl)Prx1-cre mice and osteoporosis(OP) models.Therefore, our study shows that SEs orchestrate the osteogenesis of MSCs by targeting ZBTB16 expression, which provides an attractive focus and therapeutic target for osteoporosis.Wenhui Yu Zhongyu Xie Jinteng Li Jiajie Lin Zepeng Su Yunshu Che Feng Ye Zhaoqiang Zhang Peitao Xu Yipeng Zeng Xiaojun Xu Zhikun Li Pei Feng Rujia Mi Yanfeng Wu Huiyong Shen 2023Bone Research2023,11,3:1
14Kinetic Limits of Graphite Anode for Fast‑Charging Lithium‑Ion Batteries显示文摘Fast-charging lithium-ion batteries are highly required,especially in reducing the mileage anxiety of the widespread electric vehicles.One of the biggest bottlenecks lies in the sluggish kinetics of the Li^(+)intercalation into the graphite anode;slow intercalation will lead to lithium metal plating,severe side reactions,and safety concerns.The premise to solve these problems is to fully understand the reaction pathways and rate-determining steps of graphite during fast Li^(+)intercalation.Herein,we compare the Li^(+)diffusion through the graphite particle,interface,and electrode,uncover the structure of the lithiated graphite at high current densities,and correlate them with the reaction kinetics and electrochemical performances.It is found that the rate-determining steps are highly dependent on the particle size,interphase property,and electrode configuration.Insufficient Li^(+)diffusion leads to high polarization,incomplete intercalation,and the coexistence of several staging structures.Interfacial Li^(+)diffusion and electrode transportation are the main rate-determining steps if the particle size is less than 10μm.The former is highly dependent on the electrolyte chemistry and can be enhanced by constructing a fluorinated interphase.Our findings enrich the understanding of the graphite structural evolution during rapid Li^(+)intercalation,decipher the bottleneck for the sluggish reaction kinetics,and provide strategic guidelines to boost the fast-charging performance of graphite anode.Suting Weng Gaojing Yang Simeng Zhang Xiaozhi Liu Xiao Zhang Zepeng Liu Mengyan Cao Mehmet Nurullah Ateş Yejing Li Liquan Chen Zhaoxiang Wang Xuefeng Wang 2023Nano-Micro Letters2023,15,11:1
15Localized-domains staging structure and evolution in lithiated graphite显示文摘Intercalation provides to the host materials a means for controlled variation of many physical/chemical properties and dominates the reactions in metal‐ion batteries.Of particular interest is the graphite intercalation compounds with intriguing staging structures,which however are still unclear,especially in their nanostructure and dynamic transition mechanism.Herein,the nature of the staging structure and evolution of the lithium(Li)‐intercalated graphite was revealed by cryogenic‐transmission electron microscopy and other methods at the nanoscale.The intercalated Li‐ions distribute unevenly,generating local stress and dislocations in the graphitic structure.Each staging compound is found macroscopically ordered but microscopically inhomogeneous,exhibiting a localized‐domains structural model.Our findings uncover the correlation between the long‐range ordered structure and short‐range domains,refresh the insights on the staging structure and transition of Li‐intercalated/deintercalated graphite,and provide effective ways to enhance the reaction kinetic in rechargeable batteries by defect engineering.Suting Weng Siyuan Wu Zepeng Liu Gaojing Yang Xiaozhi Liu Xiao Zhang Chu Zhang Qiuyan Liu Yao Huang Yejing Li Mehmet NAteş Dong Su Lin Gu Hong Li Liquan Chen Ruijuan Xiao Zhaoxiang Wang Xuefeng Wang 2023Carbon Energy2023,5,1:1
16Effect of microbial fermentation on the sensory characteristics and chemical compositions of Chinese sweet tea(Lithocarpus litseifolius(Hance)Chun)显示文摘Sweet tea,which has hundreds of years of use among in Chinese folk,is a traditional herbal tea with pleasant sweetness,bitterness and astringency.In the current study,we used traditional microbial fermentation to improve sensory characteristics of sweet tea,especially for the reduction of bitterness and astringency.The dynamic changes of non-volatile,volatile compounds and microbial community were investigated during microbial fermentation.The contents of polyphenols,flavonoids,soluble sugar,soluble protein,catechins and dihydrochalcones decreased significantly while the tea pigments,free amino acids and gallic acid content inversely increased during microbial fermentation.A total of 61 volatile compounds were identified and quantified in sweet tea,of which 20 key compounds were identified as odor active compounds(OAV),including 3 aldehydes,1 ketone,4 alcohols,9 esters,4 alkenes and 3 other compounds.In addition,eight fungi and four bacteria were considered as core microorganisms,such as Aspergillus,Alternaria,Cladosporium,Epicoccum,Itersonilia,Penicillium,Periconia,Wallemia,Aureimonas,Enterobacter,Klebsiella and Stenotrophomonas,which were significantly correlated with non-volatile compounds and flavor compounds.These results provided theoretical guidance for processing of fermented sweet tea.Weimin Huang Changyi Zhang Zepeng Gu Cheng Li Zhengfeng Fang Zhen Zeng Zhiqing Zhang Bin Hu Hong Chen Wenjuan Wu Tiqiang Wang Xiguo Lan Yuntao Liu 2022Food Bioscience2022,46,2:1
17New method of pre- paration and property study of the montmorillonite modified with CTAB显示文摘ZHANG Jichu ZHANG Zepeng HU Bo 2011Advanced Materials Research2011,284,:1
18Synergistic effect of cationic and anionic surfactants for the modification of Ca-montmo- rillonite显示文摘ZHANG Zepeng ZHANG Jichu LIAO Libing 2013Materials Research Bulletin2013,48,5:1
19MIL-101(Cr)-decorated Ti/TiO_(2) anode for electrochemical oxidation of aromatic pollutants from water显示文摘Hydroxyl radicals(·OH) generated on anode play a vital role in electrochemical oxidation(EO) of organic pollutants for water treatment. Inspired by the four-electron oxygen evolution reaction(OER), we supposed an anode-selection strategy to stabilize deeply oxidized states(*O and*OOH) which are beneficial to generating·OH. To verify the hypothesis, a candidate anode component(MIL-101(Cr), a well-known metal-organic framework with active variable-valence transition metal centers) was used to coat Ti/TiO_(2)plate to fabricate anodes. Compared to TiO_(2)(101) plane on undecorated anode surface, fast and complete removal of aniline and phenol, and improved energy utilization were achieved on MIL-101(Cr)-coatedTi/TiO_(2)anode. Mechanism investigation, including pollutant degradation pathways, showed the predominate contribution(69.60%–75.13%) of·OH in pollutant mineralization. Density functional theory(DFT)computations indicated Cr site in MIL-101(Cr) was more conducive to stabilizing*O and*OOH, leading to thermodynamical spontaneous generation of·OH. This work opens up an exciting avenue to explore·OH production, and supplies a useful guidance to the development of anode materials for EO process.Zepeng Zhang Yunyun Li Longzhang Dong Zhonglong Yin Ziqi Tian Weiben Yang Zhen Yang 2023Chinese Chemical Letters2023,34,2:0
20Optimum Driving System Design for Dual-Motor Pure Electric Vehicles显示文摘A pure electric vehicle driven by dual motors is taken as the research object and the driving scheme of the driving motor is improved to increase the transmission efficiency of existing electric vehicles.Based on the architecture of the transmission system,we propose vehicle performance parameters and performance indexes of a pure electric vehicle,a time-sharing driving strategy of dual motors.First,the parameters of the battery,motor,and transmission system are matched.Then,the electric vehicle transmission model is built in Amesim and the control strategy is designed in Simulink.With the optimization goal of improving the vehicle’s dynamic performance and driving range,the optimal parameters are determined through analysis.Finally,the characteristics of the motor are tested on the bench.The results show that the energy-saving potential of the timesharing driven double motor is higher,and the driving mileage of the double motor drive is increased by 4%.Hongwei Zhang Weichi Chen Zhuangzhuang Shang Zhifeng Xu Zepeng Gao Yong Chen Hongbin Ren 2020Journal of Beijing Institute of Technology2020,29,4:0
返回顶部 每页显示:
共2页 首页 上一页 第1页 下一页 末页 /2 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费