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131篇 您的检索式:作者名="Zenos"
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1Contrast-enhanced ultrasound of histologically proven hepatic epithelioid hemangioendothelioma显示文摘AIM: To analyze contrast-enhanced ultrasound(CEUS) features of histologically proven hepatic epithelioid hemangioendothelioma(HEHE) in comparison to other multilocular benign focal liver lesions(FLL).METHODS: Twenty-five patients with histologically proven HEHE and 45 patients with histologically proven multilocular benign FLL were retrospectively reviewed. Four radiologists assessed the CEUS enhancement pattern in consensus.RESULTS: HEHE manifested as a single(n = 3) or multinodular(n = 22) FLL. On CEUS, HEHE showed rim-like(18/25, 72%) or heterogeneous hyperenhancement(7/25, 28%) in the arterial phase and hypoenhancement(25/25, 100%) in the portal venous and late phases(PVLP), a sign of malignancy. Eighteen patients showed central unenhanced areas(18/25, 72%); in seven patients(7/25, 28%), more lesions were detected in the PVLP. In contrast, all patients with hemangioma and focal nodular hyperplasia showed hyperenhancement as the most distinctive feature(P < 0.01).CONCLUSION: CEUS allows for characterization of unequivocal FLL. By analyzing the hypoenhancement in the PVLP, CEUS can determine the malignant nature of HEHE.Yi Dong Wen-Ping Wang Vito Cantisani Mirko D'Onofrio Andre Ignee Lorenzo Mulazzani Adrian Saftoiu Zeno Sparchez Ioan Sporea Christoph F Dietrich 2016World Journal of Gastroenterology2016,22,19:21
2Nitrate induction triggers different transcriptional changes in a high and a low nitrogen use efficiency maize inbred line显示文摘In higher plants, NO3 can induce its own uptake and the magnitude of this induction is positively related to the external anion concentration. This phenomenon has been characterized in both herbaceous and woody plants. Here,different adaptation strategies of roots from two maize(Zea mays L., ZmAGOs) inbred lines differing in nitrogen use efficiency(NUE) and exhibiting different timing of induction were discussed by investigating NO3 ‐induced changes in their transcriptome. Lo5 line(high NUE) showing the maximum rate of NO3 uptake 4 h after the provision of 200 mmol/L NO3 treatment modulated a higher number of transcripts relative to T250(low NUE) that peaked after 12 h. The two inbred lines share only 368 transcripts that are modulated by the treatment with NO3 and behaved differently when transcripts involved in anion uptake and assimilation were analyzed. T250 line responded to the NO3 induction modulating this group of Researchgenes as reported for several plant species. On the contrary,the Lo5 line did not exhibit during the induction changes in this set of genes. Obtained data suggest the importance of exploring the physiological and molecular variations among different maize genotypes in response to environmental clues like NO3 provision, in order to understand mechanisms underlying NUE.Anita Zamboni Stefania Astolfi Sabrina Zuchi Youry Pii Katia Guardini Paola Tononi Zeno Varanini 2014Journal of Integrative Plant Biology2014,56,11:6
3Viscoelastic tests in liver disease: where do we stand now?显示文摘Hemostasis is a complex physiological process based on the balance between procoagulant and anticoagulant systems to avoid pathological bleeding or thrombosis.The changes in standard coagulation tests in liver disease were assumed to reflect an acquired bleeding disorder,and cirrhotic patients were considered naturally anticoagulated.In the light of the new evidence,the theory of rebalanced hemostasis replaced the old concept.According to this model,the hemostatic alteration leads to a unique balance between pro-coagulant,anticoagulant,and fibrinolytic systems.But the balance is fragile and may prone to bleeding or thrombosis depending on various risk factors.The standard coagulation tests[INR(international normalized ratio),platelet count and fibrinogen]only explore parts of the hemostasis,not offering an entire image of the process.Rotational thromboelastometry(ROTEM)and thromboelastography(TEG)are both point of care viscoelastic tests(VET)that provide real-time and dynamic information about the entire hemostasis process,including clot initiation(thrombin generation),clot kinetics,clot strength,and clot stability(lysis).Despite prolonged PT/INR(international normalized ratio of prothrombin time)and low platelet counts,VET is within the normal range in many patients with both acute and chronic liver disease.However,bleeding remains the dominant clinical issue in patients with liver diseases,especially when invasive interventions are required.VET has been shown to asses more appropriately the risk of bleeding than conventional laboratory tests,leading to decrial use of blood products transfusion.Inappropriate clotting is common but often subtle and may be challenging to predict even with the help of VET.Although VET has shown its benefit,more studies are needed to establish cut-off values for TEG and ROTEM in these populations and standardization of transfusion guidelines before invasive interventions in cirrhotic patients/orthotopic liver transplantation.Alina Buliarca Adelina Horhat Tudor Mocan Rares Craciun Bogdan Procopet Zeno Sparchez 2021World Journal of Gastroenterology2021,27,23:3
4Endoscopic or percutaneous biliary drainage in hilar cholangiocarcinoma:When and how?显示文摘Hilar cholangiocarcinoma (hCCA) is a primary liver tumor associated with a dimprognosis. The role of preoperative and palliative biliary drainage has long beendebated. The most common techniques are endoscopic retrograde cholangiopancreatography(ERCP) and percutaneous transhepatic biliary drainage (PTBD);however, recently developed endoscopic ultrasound-assisted methods are gainingmore atention. Selecting the best available method in any specific scenario iscrucial, yet sometimes challenging. Thus, this review aimed to discuss theavailable techniques, indications, perks, pitfalls, and timing-related issues in themanagement of hCCA. In a preoperative setting, PTBD appears to have someadvantages: low risk of postprocedural complications (namely cholangitis) andbetter priming for surgery. For palliative purposes, we propose ERCP/PTBDdepending on the experience of the operators, but also on other factors: the levelof bilirubin (if very high, rather PTBD), length of the stenosis and the presence ofcholangitis (PTBD), ERCP failure, or altered biliary anatomy.Tudor Mocan Adelina Horhat Emil Mois Florin Graur Cristian Tefas Rares Craciun Iuliana Nenu Mihaela Spârchez Zeno Sparchez 2021World Journal of Gastrointestinal Oncology2021,13,12:3
5Epilepsy triggered by mefloquine in an adult traveler to Uganda显示文摘We report a case of a traveler who visited Uganda for 8 d, and took mefloquine one tablet/week for malaria prophylaxis. After the second dose, he suffered from two episodes of loss of consciousness with seizures, therefore mefloquine was discontinued. During the flight back after full recovery, seizures reoccurred while he was on board, he was disembarked in Addis Ababa and then transferred to Nairobi. After repatriation to Italy, he experienced four other similar episodes. The patient was still on full dose anticonvulsant therapy one year and a half after, as any attempt at reduced dose was unsuccessful. Currently, three agents(mefloquine, atovaquone/proguanil, and doxycycline) are recommended for malaria chemoprophylaxis, with similar efficacy but different adverse event profiles, regimens, and prices. Considering that mefloquine is associated with a higher risk of neurologic and psychiatric adverse events than the alternative regimens, we suggest considering mefloquine as a second line choice after atovaquone/progua-nil and doxycycline for short-term travelers.Federico Gobbi Andrea Rossanese Dora Buonfrate Andrea Angheben Chiara Postiglione Zeno Bisoffi 2014World Journal of Clinical Cases2014,2,1:2
6一座传授木材技术的木建筑显示文摘在瑞士的汝拉山脚下,有一座人口约5万的小城市——比尔(Biel/Bienne),自19世纪起就一直拥有繁荣的工业和手表制造业。与这座城市的工业氛围相得益彰的,是充满实用精神的应用科学教育。所属于伯尔尼应用科学大学(Bern University of Applied Sciences)的比尔高等木材技术学校(Higher Technical School of Wood Biel,HTS)即坐落于这里。Marcel Meili Markus Peter Zeno Vogel Thomas Kühne Marc Loeliger Andreas Schmidt Thomas Schnabel Urs Schnenberger Othmar Villiger 2018世界建筑2018,,7:2
7Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials显示文摘JENS KONDRUP HENRIK H?JGAARD RASMUSSEN OLE HAMBERG ZENO STANGA 2003Clinical Nutrition2003,,3:2
8Evaluating OpenFace:an open-source automatic facial comparison algorithm for forensics显示文摘This article studies the application of models of OpenFace(an open-source deep learning algorithm)to forensics by using multiple datasets.The discussion focuses on the ability of the software to identify similarities and differences between faces based on images from forensics.Experiments using OpenFace on the Labeled Faces in the Wild(LFW)-raw dataset,the LFW-deep funnelled dataset,the Surveillance Cameras Face Database(SCface)and ForenFace datasets showed that as the resolution of the input images worsened,the effectiveness of the models degraded.In general,the effect of the quality of the query images on the efficiency of OpenFace was apparent.Therefore,OpenFace in its current form is inadequate for application to forensics,but can be improved to offer promising uses in the field.Angeliki Fydanaki Zeno Geradts 2018Forensic Sciences Research2018,3,3:2
9Clothing identification via deep learning:forensic applications显示文摘Attribute-based identification systems are essential for forensic investigations because they help in identifying individuals.An item such as clothing is a visual attribute because it can usually be used to describe people.The method proposed in this article aims to identify people based on the visual information derived from their attire.Deep learning is used to train the computer to classify images based on clothing content.We first demonstrate clothing classification using a large scale dataset,where the proposed model performs relatively poorly.Then,we use clothing classification on a dataset containing popular logos and famous brand images.The results show that the model correctly classifies most of the test images with a success rate that is higher than 70%.Finally,we evaluate clothing classification using footage from surveillance cameras.The system performs well on this dataset,labelling 70%of the test images correctly.Marianna Bedeli Zeno Geradts Erwin van Eijk 2018Forensic Sciences Research2018,3,3:2
10Blocked isocyanates Ⅲ Part B: Uses and applications of blocked isocyanates 显示文摘Douglas A W Zeno W W J 2001Progress in Organic Coatings2001,41,:1
11Advance image segmentation显示文摘Zeno S D 1984Image Vision Computing1984,1,:1
12Should triglycerides and the triglycerides to high-density lipoprotein cholesterol ratio be used as surrogates for insulin resistance? 显示文摘Kim-DornerSJ Deuster PA Zeno SA 2010Metabolism2010,59,:1
13Contrast - Enhanced Ultrasound in Assessing Therapeutic Response in Ablative Treatments of Hepatocellular Carcinoma 显示文摘Zeno Sparchez Pompilia Radu Ofelia Anton 2009Gastrointestin Liver Dis2009,18,2:1
14Novel approaches in search for biomarkers of cholangiocarcinoma显示文摘Cholangiocarcinoma(CCA)arises from the ductular epithelium of the biliary tree,either within the liver(intrahepatic CCA)or more commonly from the extrahepatic bile ducts(extrahepatic CCA).This disease has a poor prognosis and a growing worldwide prevalence.The poor outcomes of CCA are partially explained by the fact that a final diagnosis is challenging,especially the differential diagnosis between hepatocellular carcinoma and intrahepatic CCA,or distal CCA and pancreatic head adenocarcinoma.Most patients present with an advanced disease,unresectable disease,and there is a lack in non-surgical therapeutic modalities.Not least,there is an acute lack of prognostic biomarkers which further complicates disease management.Therefore,there is a dire need to find alternative diagnostic and follow-up pathways that can lead to an accurate result,either singlehandedly or combined with other methods.In the'-omics'era,this goal can be attained by various means,as it has been successfully demonstrated in other primary tumors.Numerous variants can reach a biomarker status ranging from circulating nucleic acids to proteins,metabolites,extracellular vesicles,and ultimately circulating tumor cells.However,given the relatively heterogeneous data,extracting clinical meaning from the inconsequential noise might become a tall task.The current review aims to navigate the nascent waters of the non-invasive approach to CCA and provide an evidence-based input to aid clinical decisions and provide grounds for future research.Lavinia-Patricia Mocan Maria Ilieș Carmen Stanca Melincovici Mihaela Spârchez RareșCrăciun Iuliana Nenu Adelina Horhat Cristian Tefas Zeno Spârchez Cristina Adela Iuga Tudor Mocan Carmen Mihaela Mihu 2022World Journal of Gastroenterology2022,28,15:1
15Adsorption and polymer film formation on metal nanoclusters显示文摘Tadd E Zeno A Zubris M 2003Macromolecules2003,36,:1
16A'Post-Honeymoon Period' measles outbreak in Muyinga sector, Burundi显示文摘Rober T C Robert W Zeno B 1994International Journal of Epidemiology1994,23,1:1
17Nutritional screening tools in daily clinical practice: the focus on cancer显示文摘Michèle Leuenberger Silvia Kurmann Zeno Stanga 2010Supportive Care in Cancer2010,,2:1
18Forensic visual evidence显示文摘Jurrien Bijhold Arnout Ruifrok Zeno Geradts 2010A Review2010,,:1
19A‘Post - Honeymoon Period' measles outbreak in muyinga sector , Burundi 显示文摘Rober T C Robert W Zeno B 1994International Journal of Epidemiology1994,23,1:1
20Infection rates after 3175 total hip and total knee replacements performed with and without a horizontal unidirectional filtered air-flow System 显示文摘Salvati E A Robinson R P Zeno S M 1982J Bone Joint Surg (Am)1982,64,4:1
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