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| 1 | Predictive value of multi-detector computed tomography for accurate diagnosis of serous cystadenoma:Radiologic-pathologic correlation显示文摘AIM:To identify multi-detector computed tomography(MDCT) features most predictive of serous cystadenomas(SCAs),correlating with histopathology,and to study the impact of cyst size and MDCT technique on reader performance.METHODS:The MDCT scans of 164 patients with surgically verified pancreatic cystic lesions were reviewed by two readers to study the predictive value of various morphological features for establishing a diagnosis of SCAs.Accuracy in lesion characterization and reader conf idence were correlated with lesion size(≤3cm or≥3cm) and scanning protocols(dedicated vs routine).RESULTS:28/164 cysts(mean size,39 mm;range,8-92mm) were diagnosed as SCA on pathology.The MDCT features predictive of diagnosis of SCA were microcystic appearance(22/28,78.6%),surface lobulations(25/28,89.3%) and central scar(9/28,32.4%).Stepwise logistic regression analysis showed that only microcystic appearance was signifi cant for CT diagnosis of SCA(P=0.0001).The sensitivity,specificity and PPV of central scar and of combined microcystic appearance and lobulations were 32.4%/100%/100% and 68%/100%/100%,respectively.The reader confidence was higher for lesions>3cm(P=0.02) and for MDCT scans performed using thin collimation(1.25-2.5mm) compared to routine 5 mm collimation exams(P>0.05).CONCLUSION:Central scar on MDCT is diagnostic of SCA but is seen in only one third of SCAs.Microcystic morphology is the most significant CT feature in diagnosis of SCA.A combination of microcystic appearance and surface lobulations offers accuracy comparable to central scar with higher sensitivity. | Anjuli A Shah Nisha I Sainani Avinash Kambadakone Ramesh Zarine K Shah Vikram Deshpande Peter F Hahn Dushyant V Sahani | 2009 | World Journal of Gastroenterology2009，15，22： | 11 |
| 2 | Antioxidant, antimicrobial and cytotoxic potential of condensed tannins from Leucaena leucocephala hybrid-Rendang显示文摘Condensed tannins(CTs)are one of the promising compounds due to their potentially health-promoting qualities.In this study,CTs were extracted from a Leucaena leucocephala hybrid-Rendang and subjected to various biological studies including antioxidant(using Ferric reducing antioxidant power(FRAP),DPPH and ABTS radical scavenging assay),anti-microbial(against different pathogens)and cytotoxic activities(toward human breast adenocarcinoma(MCF-7),human colon carcinoma(HT29),human cervical carcinoma(HeLa)and human liver carcinoma(HepG2)cell lines)in cancer cells through in vitro experiments.The structural characteristics and purity of CTs extract were determined using 13C NMR.The results showed that CTs exhibited higher in vitro antioxidant activities(2257.12±80.55 mg TEAC/g extract,605.3±1.82 mg TEAC/g extract and 1014.03±1.20 mg TEAC/g extract in FRAP,ABTS and DPPH assay,respectively)and demonstrated anti-microbial activities toward selected Gram’s positive and Gram’s negative bacteria tested with MIC and MBC value at 6.25–50 mg/mL.Furthermore,among other selected cancer cells,CTs also demonstrated cytotoxic activity toward human breast cancer cells(MCF-7)(IC50=38.33±2.08mg/mL).Characteristic of apoptosis such as cell shrinkage,nuclear condensation and apoptotic bodies were shown in MCF-7.These preliminary investigations have provided scientific rationale to use CTs as an alternative therapy for various oxidative and inflammatory associated diseases.©2016 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved. | Mazni Abu Zarin Ho Yin Wan Azizul Isha Nurdin Armania | 2016 | Food Science and Human Wellness2016，5，2： | 9 |
| 3 | Arterial enlargement, tortuosity, and intimal thickening in response to sequential exposure to high and low wall shear stress显示文摘 | Eiketsu Sho Hiroshi Nanjo Mien Sho Mikio Kobayashi Masayo Komatsu Koichi Kawamura Chengpei Xu Christopher K Zarins Hirotake Masuda | 2004 | Journal of Vascular Surgery2004，，3： | 2 |
| 4 | Reporting standards for endovascular aortic aneurysm repair显示文摘 | Elliot L. Chaikof Jan D. Blankensteijn Peter L. Harris Geoffrey H. White Christopher K. Zarins Victor M. Bernhard Jon S. Matsumura James May Frank J. Veith Mark F. Fillinger Robert B. Rutherford K.Craig Kent | 2002 | Journal of Vascular Surgery2002，，： | 2 |
| 5 | Influence of storage on peptides subunits composition of rice oryzenin显示文摘 | Chrastil J Zarins Z | 1992 | Journal of Agricultureand Food Chemistry1992，40，： | 1 |
| 6 | Finite element modeling of blood flow in arteries 显示文摘 | Thomas J R Hughes Zarins C K | 1998 | Computer Methods in Applied Mechanics and Engineering1998，158，： | 1 |
| 7 | Finite element modeling of blood flow in arteries显示文摘 | Hughes DJR Zarins CK | 1998 | Computer Methods in Applied Mechanics and Engineering1998，158，： | 1 |
| 8 | Compensatory enlargement of human atherosclerotic coronary arteries显示文摘 | Glagov S Weisenberg E Zarins CK | 1987 | N Engl J Med1987，316，： | 1 |
| 9 | What is the signifi- cance of endoleaks and endotension显示文摘 | Heikkinen MA Arko FR Zarins CK | 2004 | Surg Clin North Am2004，84，5： | 1 |
| 10 | Retarding effect of lowered heart rate on coronary atherosclerosis显示文摘 | Glagov S Zarins CK | 1984 | Science1984，226，： | 1 |
| 11 | Relative contribution of wall shear stress and injury in experimental intimal thickening at PTFE end-to-side arterial anastomoses 显示文摘 | Lath F Jones SA Zarins CK | 2002 | J Biomech Eng2002，124，1： | 1 |
| 12 | Shear stress regulation of artery lumen diameter in experimental atherogenesis显示文摘 | Zarins CK Zatina MA Giddens DP | 1987 | J Vasc Surg1987，5，： | 1 |
| 13 | Acute muscle and tendon injuries in athletes 显示文摘 | ZARINS B CIULLO J V | 1983 | Clin Sports Med1983，，2： | 1 |
| 14 | Pulsatile flow and atherosclerosis in the human carotid bifurcation :Positive correlation between plaque location and low oscillating shear stress显示文摘 | Ku D N Giddens D P Zarins C K | 1985 | Arteriosclerosis1985，5，3： | 1 |
| 15 | Pulsatile flow and atherosclerosis in the human carotid bifurcation显示文摘 | Ku DN Giddens DP Zarins C K | 1985 | Atherosclerosis1985，5，： | 1 |
| 16 | The impact of aortic endografts on renal function显示文摘 | Alsac JM Zarins CK Heikkinen MA | 2005 | J Vasc Surg2005，41，6： | 1 |
| 17 | Hemodynamics and atherosclerosis: insights and perspectives gained from studies of human arteries 显示文摘 | Zarins C Giddens DP and Ku DN | 1988 | Arch Pathol Lab Med1988，112，10： | 1 |
| 18 | Pulsatile flow and atherosclerosis in the human carotid bifurcation: positive correlation between plaque location and low oscillating shear stress显示文摘 | Ku DN Giddens DP Zarins CK Glagov S | 1985 | Arterioselerosis1985，5，： | 1 |
| 19 | Compensatory enlargement of human atherosclerotic coronary arteries显示文摘 | Glagov S Weisenberg E Zarins CK | 1987 | N Engl J Med1987，316，： | 1 |
| 20 | Influence of storage on peptide subunitcomposition of rice oryzenin 显示文摘 | Chrastil J Zarins Z M | 1992 | Journal of Agricultural and FoodChemistry1992，40，6： | 1 |
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