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| 1 | Recent Advances in Researches on Physiologically Active Substances in Holothurians显示文摘In this report, we reviewed recent literature on physiologically active substances from sea cucumbers (SCs) andtheir activities together with results obtained from our study. Preventive properties against lipid metabolism were reported inrats using a whole SC preparation with no particular constituent specified. Administration of the preparation lowered serumand hepatic cholesterol levels and improved the HDL/LDL ratio. These functions may be attributed to the stimulatory effectof the extract on the secretion of cholesterol in feces. Novel fucosylated chondroitin sulfates (FCSs) from Ludwigothureagrisea significantly induced fibroblast growth factor 2-dependent angiogenesis in human umbilical vein endothelial cells (HU-VECs). The proangiogenetic activity seemed attributable to the action of the sulfated fucose branches on the polysaccharide.SCs contain mycosporine-like amino acids (MAAs) that are capable of absorbing UV. A biogenetic precursor of MAAs wasfirst reported in SCs. The anti-proliferative effects of a branched chain fatty acid from a sea cucumber on prostate cancercells was reported with the activity of 5-lipoxygenase. Glycosphingolipid constituents in SCs have been systematically ana-lyzed over the past ten years. The results showed that the gangliosides in several SCs differed from those of mammals in thata sialic acid of SC gangliosides directly binded to glucose of cerebroside. Neuritogenic activity of the glycosphingolipids wasdemonstrated in vitro experiments and may lead to the development of therapeutic products for neurological disorders. Ourstudy also showed that sphingoid bases, the hydrolyzed products of glycosphingolipids from SCs, induced significant apoptosisin several tumor cell lines. | Hirata Takashi Zaima Nobuhiro Yamashita Kyoko Noguchi Ryoko XUE Changhu Sugawara Tatsuya | 2005 | Journal of Ocean University of China2005，4，3： | 14 |
| 2 | Ag/AAO纳米有序阵列复合结构等效光学参量的确定显示文摘引入厚度偏差Δd,修正了薄膜透射率表达式.基于Ag/AAO纳米有序阵列复合结构实验透射光谱(500—2700nm)的两条极值包络线,定义了一个优化函数,结合最优化数值算法尝试确定具有较强吸收的Ag/AAO纳米有序阵列复合结构的等效光学参量.由此计算了该结构的等效折射率n、等效消光系数k、平均等效厚度-d以及厚度偏差Δd.该方法对Ag/AAO纳米复合结构平均等效厚度的相对计算误差仅为0.3%,与实测厚度基本一致,且Ag/AAO纳米复合结构的模拟透射谱与实验透射光谱在500—2700nm波段范围内相符.这表明该计算方法可有效确定Ag/AAO纳米复合结构的等效光学参量,并与实验结果是自洽的. | 王建 王成伟 李燕 刘维民 Zaima Shigeaki | 2005 | 物理学报2005，54，12： | 5 |
| 3 | Thermal stresses problems in industry 1 : On thermoelastie distortion in machine metals显示文摘 | Takeuti Y Zaima S Noda N | 1978 | J Thermal Stresses1978，1，2： | 1 |
| 4 | Re-ignition surges at reactor current interruption in cable-system GIS显示文摘 | ZAIMA E NISHIWAKI S ISHIKAWA M | 1990 | IEEE Transaction on Power Delivery1990，5，2： | 1 |
| 5 | Visualization of central stellate fibrosis in hyaline vascular type Castleman's disease显示文摘 | Ota T Mitsuyoshi A Zaima M | | 0，，838： | 1 |
| 6 | Interfacial reactions of Ti/ and Zr/Si1-xGex/Si contacts with rapid thermal annealing显示文摘 | Yasuda Y Nakatsuka O Zaima S | 2000 | Thin Solid Films2000，373，1： | 1 |
| 7 | Studies on the constituents from the fruits of Phaleria macrocarpa 显示文摘 | Oshimi S Zaima K Matsuuo Y | 2008 | Journal of Natural Medicines2008，62，2： | 1 |
| 8 | Clinical course of 44 cases of localized type vitiligo 显示文摘 | Zaima H Koga M | 2002 | J Dermatol2002，29，： | 1 |
| 9 | Thermal stresses problems in industry 1 : On thermoelastic distortion in machine metals显示文摘 | Takeuti Y Zaima S Ncda N | 1978 | Thermal Stresses1978，1，2： | 1 |
| 10 | Hydroxylated and non-hydroxylated sulfatide are distinctly distributed in the human cerebral cortex显示文摘 | Yuki D Sugiura Y Zaima N Akatsu H Hashizume Y Yamamoto T Fujiwara M Sugiyama K Setou M | | 0，，： | 1 |
| 11 | Thermal stresses problems in industry 1: On thermoelastic distortion in machine metals显示文摘 | Takeuti Y Zaima S Noda N | 1978 | Thermal Stresses1978，1，2： | 1 |
| 12 | Thermal stresses problems in industry 1:on thermo-elastic distortion in machine metals显示文摘 | Takeuti Y Zaima S Noda N | 1978 | Thermal Stresses1978，1，： | 1 |
| 13 | Dislocation reduction of GaSb on GaAs by metalorganic chemical vapor deposition with epitaxial lateral overgrowth 显示文摘 | ZAIMA K HASHIMOTO R EZAKI M | 2008 | J of Crystal Growth2008，310，23： | 1 |
| 14 | Preparation and properties of Ta2O5films by LPCVD for ULSI application显示文摘 | ZAIMA S FURUTA T YASUDA Y | 1990 | J Electrochem Soc1990，137，4： | 1 |
| 15 | Visualization of central stellate fibrosis in hyaline vascular type Castleman disease 显示文摘 | Ota T Mitsuyoshi A Zaima A | 1997 | Br J Rad1997，70，： | 1 |
| 16 | Observation of lightning by means of Time-of-arrival type lightning location system显示文摘 | Zaima Eiichi Mochizuki | 1997 | Electrical Engineer- ing in Japan(English Translation of Denki Gakkai Ronbunshi)1997，120，1： | 1 |
| 17 | Study of lightning surge overvoltages at substations due to direct lightning strokes to phase conductors显示文摘 | Takami J Okabe S Zaima E | 2010 | IEEE Transactions on Power Delivery2010，25，1： | 1 |
| 18 | Fibroid in pregnancy:characteristics,complica-tions and management显示文摘 | Zaima A Ash A | 2011 | Postgrad Med J2011，87，1034： | 1 |
| 19 | Lightning surge overvoltages at substations due to backflashover with assumed lightning current waveforms based on observations显示文摘 | Takami J Okabe S Zaima E | 2010 | IEEE Transactions on Power Delivery2010，25，4： | 1 |
| 20 | Observation of current waveshape of lighting strokes on transmission towers 显示文摘 | Narita T Yamada T Zaima E | 2000 | IEEE Trans PD2000，15，1： | 1 |
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