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| 1 | Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development显示文摘Dear Editor,Previously,the Mendelian phe no types in huma n oocyte maturation arrest,fertilization failure and early embryonic arrest,are largely underestimated.In recent years,'missing'Men delian phe no types and genes in these processes are beginning to be uncovered by us and others(Huang et al.,2014;Alazami et al..2015;Feng et al.,2016;Xu et al.,2016;Chen et al.,2017;Sang et al.,2019).However,the genetic basis for majority of patients resulting from abnormalities in these phe no types remains to be elucidated. | Lin Zhao Songguo Xue Zhongyuan Yao Juanzi Shi Biaobang Chen Ling Wu Lihua Sun Yao Xu Zheng Yan Bin Li Xiaoyan Mao Jing Fu Zhihua Zhang Jian Mu Wenjing Wang Jing Du Shuai Liu Jie Dong Weijie Wang Qiaoli Li Lin He Li Jin Xiaozhen Liang Yanping Kuang Xiaoxi Sun Lei Wang Qing Sang | 2020 | Protein & Cell2020,11,12: | 10 |
| 2 | A 2-kb Mycovirus Converts a Pathogenic Fungus into a Beneficial Endophyte for Brassica Protection and Yield Enhancement显示文摘Mycoviruses are viruses that infect fungi,and hypovirulence-associated mycoviruses have the potential to control fungal diseases.However,it is unclear how mycovirus-mediated hypovirulent strains live and survive in the field,and no mycovirus has been applied for field crop protection.In this study,we found that a previously identified small DNA mycovirus(SsHADV-1)can convert its host,Sclerotinia sclerotiorum,from a typical necrotrophic pathogen to a beneficial endophytic fungus.SsHADV-1 downregulates the expression of key pathogenicity factor genes in S.sclerotiorum during infection.When growing in rapeseed,the SsHADV-1-infected strain DT-8 significantly regulates the expression of rapeseed genes involved in defense,hormone signaling,and circadian rhythm pathways.As a result,plant growth is promoted and disease resistance is enhanced.Field experiments showed that spraying DT-8 at the early flowering stage can reduce the disease severity of rapeseed stem rot by 67.6%and improve yield by 14.9%.Moreover,we discovered that SsHADV-1 could also infect other S.sclerotiorum strains on DT-8-inoculated plants and that DT-8 could be recovered from dead plants.These findings suggest that the mycoviruses may have the ability to shape the origin of endophytism.Our discoveries suggest that mycoviruses may influence the origin of endophytism and may also offer a novel strategy for disease control in which mycovirus-infected strains are used to improve crop health and release mycoviruses into the field. | Hongxiang Zhang Jiatao Xie Yanping Fu Jiasen Cheng Zheng Qu Zhenzhen Zhao Shufen Cheng Tao Chen Bo Li Qianqian Wang Xinqiang Liu Binnian Tian David B.Collinge Daohong Jiang | 2020 | Molecular Plant2020,13,10: | 9 |
| 3 | Effect of a comprehensive therapy plus Gushenyutai plaster administered at Guanyuan(CV 4) on male infertility associated with semen non-liquefaction显示文摘OBJECTIVE: To observe the clinical effect of Gushenyutai plaster administered at the Guanyuan(CV4) acupoint on male infertility associated with semen non-liquefaction.METHODS: Sixty-two male patients with infertility caused by semen non-liquefaction were random-ized into a treatment and control group. The control group received comprehensive therapy, which included oral administration of clarithromycin sustained release tablets, hip bath with Zhongyaoxiaoyan granules, prostate massage, and transurethral microwave treatment. The treatment group was administered Gushenyutai plaster in addition to the comprehensive therapy. Both groups were treated for 8 weeks. After treatment, the clinical effect and pregnancy rate were assessed and compared between the two groups.RESULTS: The effective rate of the treatment group was significantly higher than that of the control group(96.77% vs 70.97%, P<0.05) and the pregnancy rates of the treatment group and control groups were 38.71% and 16.13%, respectively(P<0.05).CONCLUSION: The effect of Gushenyutai plaster plus comprehensive therapy was better than that of the comprehensive therapy alone on male infertility induced by semen non-liquefaction. | Shaofang Peng Yanping Zheng Kangzhuang Zheng Ke Lin Juhong Wu Wenqin Zheng Yongzhong Li Yang Li Chuangjian Lin | 2014 | Journal of Traditional Chinese Medicine2014,34,6: | 6 |
| 4 | Regulation of non-classical immune parameters in immune thrombocytopenic purpura mice by a spleen-invigorating,qi-replenishing and blood-containing formula显示文摘Objective:This study investigated the regulatory effect of non-classical immune parameters on immune thrombocytopenic purpura(ITP)mice by a spleen-invigorating,qi-replenishing and blood-containing formula(SQBF).Method:A total of 80 BALB/c mice were randomly divided into four equal groups(20 mice each):control group,model group,prednisone group and spleen-invigorating,qi-replenishing and blood-containing(SQBF)group.Mice in the model group,prednisone group,and SQBF group were administered anti-platelet serum to induce ITP.The dynamic variations of platelet counts in ITP mice were measured with an automatic blood analyzer before modeling and 48 h,and 8,12 and 15 days following APS injection.Levels of b-endorphin(b-EP),vasoactive intestinal peptide(VIP)and salivary IgA(SIgA)were detected by enzyme-linked immunosorbent assay(ELISA)on 15th day of experiment.Results:SQBF enhanced peripheral blood platelet counts in ITP mice similar to that of prednisone,and both groups showed a statistically significant response compared with the model group(P<.01).The SQBF significantly decreased b-EP levels compared with the model and prednisone intervention groups(P<.05),significantly increased the levels of VIP and SIgA in ITP mice compared with the model group(P<.05)and had significant protective effects on the thymus of ITP mice compared with the model group(P<.01).Conclusions:The SQBF had a similar effect to prednisone with regards to enhancing peripheral blood platelet counts in ITP mice.Furthermore,it decreased b-EP levels and increased VIP and SIgA,and protected the thymus.This shows that,on base of the brain-gut axis functions,some non-classical immune vascular active factors or neurotransmitters are also involved in immune responses,and also have relationship with the onset of ITP and bleeding and/or hemostasis.It needs further study to determine whether a change in these active factors is related to immediate hemostasis. | Tiantian Li Hao He Li Hou Yue Xu Xiaoyong Wu Yanping Sun Lei Zheng Zhixiong Chen Xinyi Chen Bei Qin | 2015 | Journal of Traditional Chinese Medical Sciences2015,2,2: | 6 |
| 5 | Catalysis under shell: Improved CO oxidation reaction confined in Pt@h-BN core-shell nanoreactors显示文摘Core-shell nanostructures consisting of active metal cores and protective shells often exhibit enhanced catalytic performance, in which reactants can access a small part of the core surfaces through the pores in the shells. In this study, we show that Pt nanoparticles (NPs) can be embedded into few-layer hexagonal boron nitride (h-BN) overlayers, forming Pt@h-BN core-shell nanocatalysts. The h-BN shells not only protect the Pt NPs under harsh conditions but also allow gaseous molecules such as CO and O2 to access a large part of the Pt surfaces through a facile intercalation process. As a result, the Pt@h-BN nanostructures act as nanoreactors, and CO oxidation reactions with improved activity, selectivity, and stability occur at the core-shell interfaces. The confinement effect exerted by the h-BN shells promotes the Pt-catalyzed reactions. Our work suggests that two-dimensional shells can function as robust but flexible covers on nanocatalyst surfaces and tune the surface reactivity. | Mengmeng Sun Qiang Fu Lijun Gao Yanping Zheng Yangyang Li Mingshu Chen Xinhe Bao | 2017 | Nano Research2017,10,4: | 5 |
| 6 | High spatial and temporal resolution synthetic aperture phase microscopy显示文摘A new optical microscopy technique,termed high spatial and temporal resolution synthetic aperture phase microscopy(HISTR-SAPM),is proposed to improve the lateral resolution of wide-field coherent imaging.Under plane wave illumination,the resolution is increased by twofold to around 260 nm,while achieving millisecond-level temporal resolution.In HISTR-SAPM,digital micromirror devices are used to actively change the sample illumination beam angle at high speed with high stability.An off-axis interferometer is used to measure the sample scattered complex fields,which are then processed to reconstruct high-resolution phase images.Using HISTR-SAPM,we are able to map the height profiles of subwavelength photonic structures and resolve the period structures that have 198 nm linewidth and 132 nm gap(i.e.,a full pitch of 330 nm).As the reconstruction averages out laser speckle noise while maintaining high temporal resolution,HISTR-SAPM further enables imaging and quantification of nanoscale dynamics of live cells,such as red blood cell membrane fluctuations and subcellular structure dynamics within nucleated cells.We envision that HISTR-SAPM will broadly benefit research in material science and biology. | Cheng Zheng Di Jin Yanping He Hongtao Lin Juejun Hu Zahid Yaqoo Peter T.C.So Renjie Zhou | 2020 | Advanced Photonics2020,2,6: | 5 |
| 7 | A New Understanding of Channel Patterns and Facies Models of the Shallow Lake Delta Facies of Fuyu Oil Reservoir in Songliao Basin,China显示文摘摘要:在 Songliao 盆的 Fuyu 水库,在那里发生一系列开发得好的古怪的浅湖三角洲外形,它能被划分到象上面的三角洲平原 subfacies,更低的三角洲平原 subfacies,和三角洲前面 subfacies 的如此的三。在他们之中,上面的三角洲平原 subfacies 主要种近似支流隧道;更低的三角洲平原 subfacies 主要增长远侧的。全部 Fuyu 水库主要开发了 7 种支流隧道模式:proximal/ 远侧的蜿蜒地流类型支流隧道,近似 / 远侧的低蜿蜒的类型支流隧道,近似 / 远侧的直类型支流隧道,和水下的支流隧道。在这些模式之中,近似、远侧的蜿蜒地流的类型支流隧道有点酒吧并且更好的排序和泥的低内容的更大的厚度;而且,他们是主要水库并且发生在 Quan-4th 的底部成员。水下的支流隧道的沙洲有更高的泥内容,并且用作更差的水库,并且主要发生在 Quan-4th 成员的顶。 | LI Yanping CHEN Shumin SONG Yongzhong ZHANG Erhua SHEN Jiagang ZHENG Jianbin | 2008 | Acta Geologica Sinica(English Edition)2008,82,3: | 3 |
| 8 | SOLUTION OF DIFFERENT HOLES SHAPE BORDERS OF FIBRE REINFORCED COMPOSITE PLATES BY INTEGRAL EQUATIONS显示文摘有不同的洞的合成材料盘子的精确边界条件被成立在非同类的各向异性的有弹性、复杂的功能理论之上由保角的印射的方法解决复杂的洞的边界条件问题。然后要求的二压力功能基于由边界条件不可分的 Cauchy。用矩形洞和翅膀出入孔在合成材料板上打开结构和分析答案的最后的压力分布被完成。对洞边压力集中因素的影响在不同负担和纤维方向盒子下面被讨论,然后对比计算被完成女性。 | LI Cheng ZHENG Yanping CHEN Zhongzhong | 2007 | Chinese Journal of Mechanical Engineering2007,20,5: | 3 |
| 9 | INTEGRAL EQUATION METHOD'S APPLICATION IN HOLE-EDGE STRESS OF COMPOSITE MATERIAL PLATE WITH DIFFERENT SHAPED HOLES显示文摘The strength of composite plate with different hole-shapes is always one of the most important but complicated issues in the application of the composite material.The holes will lead to mutations and discontinuity to the structure.So the hole-edge stress concentration is always a serious phenomenon.And the phenomenon makes the structure strength decrease very quickly to form dangerous weak points.Most partial damage begins from these weak points.According to the complex variable functions theory,the accurate boundary condition of composite plate with different hole-shapes is founded by conformal mapping method to settle the boundary condition problem of complex hole-shapes.Composite plate with commonly hole-shapes in engineering is studied by several complex variable stress function.The boundary integral equations are founded based on exact boundary conditions.Then the exact hole-edge stress analytic solution of composite plate with rectangle holes and wing manholes is resolved.Both of offset axis loadings and its influences on the stress concentration coefficient of the hole-edge are discussed.And comparisons of different loads along various offset axis on the hole-edge stress distribution of orthotropic plate with rectangle hole or wing manhole arc madc.It can bc concluded that hole-edge with continuous variable curvatures might help to decrease the stress concentration coefficient;and smaller angle of outer load and fiber can decrease the stress peak value. | LI Cheng ZHENG Yanping | 2008 | Chinese Journal of Mechanical Engineering2008,21,6: | 3 |
| 10 | Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis显示文摘The plant aluminum(Al)-activated malate transporter ALMT1 mediates the efflux of malate to chelate the Al in acidic soils and underlies the plant Al resistance.Here we present cryo-electron microscopy(cryo-EM)structures of Arabidopsis thaliana ALMT1(AtALMT1)in the apo,malate-bound,and Al-bound states at neutral and/or acidic pH at up to 3.0Åresolution.The AtALMT1 dimer assembles an anion channel and each subunit contains six transmembrane helices(TMs)and six cytosolicα-helices.Two pairs of Arg residues are located in the center of the channel pore and contribute to malate recognition.Al binds at the extracellular side of AtALMT1 and induces conformational changes of the TM1-2 loop and the TM5-6 loop,resulting in the opening of the extracellular gate.These structures,along with electrophysiological measurements,molecular dynamic simulations,and mutagenesis study in Arabidopsis,elucidate the structural basis for Al-activated malate transport by ALMT1. | Jiangqin Wang Xiafei Yu Zhong Jie Ding Xiaokang Zhang Yanping Luo Ximing Xu Yuan Xie Xiaoxiao Li Tian Yuan Shao Jian Zheng Wei Yang Jiangtao Guo | 2022 | Cell Research2022,32,1: | 3 |
| 11 | Tensile properties analysis of CFRP-titanium plate multi-bolt hybrid joints显示文摘Hybrid joints have better tensile properties than pure bonded and bolted bolts,and are increasingly used in the aerospace field.Tensile tests are carried out for the Hybrid Bonded/Bolted(HBB)joints of Carbon Fiber Reinforced Polymer(CFRP)laminate and titanium alloy plate under different bolt numbers,and the corresponding load–displacement curves are obtained.At the same time,based on Continuum Damage Mechanics(CDM)theory,which is derived from 3D Hashin failure criteria,and a Cohesive Zone Model(CZM),the tensile strength prediction model of the composite laminate-titanium alloy plate multi-bolted HBB joint was established,and the numerical simulation results were in good agreement with the experimental height,which validate the feasibility of the model.The difference in the bearing capacity of HBB joints under different numbers of bolts is compared and analyzed.On this basis,the influence of inter-bolt distance on the tensile properties of the HBB joints is explored.The results show that the double-nail HBB joints can effectively improve the end warpage and low bearing capacity of the single-nail HBB joints.The tensile failure load of the double-nail HBB joints under the standard lap width(30 mm)is 82.6%higher than that of the single nail,the tensile failure load of the three-bolt HBB joints is 34.1%higher than that of the double nail.For the three-bolt HBB joint,the joint strength is controlled by the adhesive and the external bolt,while the internal bolt is redundant,the hybrid joint can be simplified by reducing the middle bolt.The inter-bolt distance has a great influence on the failure load of the hybrid joint.Increasing the inter-bolt distance can effectively improve the bearing capacity of the structure. | Yanping ZHENG Chaoyu ZHANG Ying TIE Xu WANG Mingkun LI | 2022 | Chinese Journal of Aeronautics2022,35,3: | 2 |
| 12 | Preservation Effect of Prochloraz-manganese Chloride Complex on Postharvest ‘Shatangju'( Citrus reticulata)Fruits显示文摘[Objective]The paper was to solve the weakness of heavy postharvest diseases and non-endurable storage of‘Shatangju',to improve the preservation effect of‘Shatangju'. [Method] Fruits were dipped in different concentrations of prochloraz-manganese chloride complex solutions. The postharvest weight loss rate,soluble solids content and decay rate of fruits were determined,and the safety of chemical agents was observed and evaluated. [Result]Prochloraz-manganese chloride complex had significant preservation effect on postharvest‘Shatangju'fruits,and the appropriate concentration was 0. 15%-0. 20%( effective content);the decay rates of fruits stored at room temperature for 15,30,45,60 and 90 d were 0,5%,< 10%,< 10% and < 30%; there was no specific changes in smell and flavor of non-decayed fruits. [Conclusion] Prochloraz-manganese chloride complex solution had significant preservation effect on ‘Shatangju'by inhibiting and reducing the growth and development of pathogenic bacteria,and the effect was much better under refrigeration condition. | Xu Chengxiang Zheng Fuqing Ma Yanping Zhang Xujia | 2016 | Plant Diseases and Pests2016,7,5: | 2 |
| 13 | A Preliminary Analysis on the Applicability of ERA5 Reanalysis Data in Guangdong Province显示文摘In order to effectively use the ERA5 reanalysis data,observation data in and around Guangdong Province was used to evaluate the reanalysis data by analyzing the correlation coefficient and deviation. The results showed that among the surface elements,the sea level pressure and air temperature performed the best reproducibility,second the relative humidity and wind speed,and they had better performance in the Pearl River Delta and its surrounding areas,while the worst was wind direction. Except the relative humidity,elements had better performance at higher levels than lower levels among the ERA5 reanalysis upper-air data. | Yanping ZHENG | 2020 | Meteorological and Environmental Research2020,11,2: | 2 |
| 14 | A durable 4-1BB-based CD19 CAR-T cell for treatment of relapsed or refractory non-Hodgkin lymphoma显示文摘Objective:Previous studies reported that 4-1BB-based CD19 chimeric antigen receptor(CAR)-T cells were more beneficial for the clinical outcomes than CD28-based CAR-T cells,especially the lower incidence rate of severe adverse events.However,the median progression-free survival(mPFS)of 4-1BB-based product Kymriah was shorter than that of CD28-based Yescarta(2.9 months vs.5.9 months),suggesting that Kymriah was limited in the long-term efficacy.Thus,a safe and durable 4-1BB-based CD19 CAR-T needs to be developed.Methods:We designed a CD19-targeted CAR-T(named as IM19)which consisted of an FMC63 scFv,4-1BB and CD3ζintracellular domain and was manufactured into a memory T-enriched formulation.A phase I/II clinical trial was launched to evaluate the clinical outcomes of IM19 in relapsed or refractory(r/r)B cell non-Hodgkin lymphoma(B-NHL).Dose-escalation investigation(at a dose of 5×10^(5)/kg,1×10^(6)/kg and 3×106/kg)was performed in 22 r/r B-NHL patients.All patients received a single infusion of IM19 after 3-day conditional regimen.Results:At month 3,the overall response rate(ORR)was 59.1%,the complete response rate(CRR)was 50.0%.The mPFS was 6 months and the 1-year overall survival rate was 77.8%.Cytokine release syndrome(CRS)occurred in 13 patients(59.1%),with 54.5%of grade 1−2 CRS.Only one patient(4.5%)experienced grade 3 CRS and grade 3 neurotoxicity.Conclusions:These results demonstrated the safety and durable efficacy of a 4-1BB-based CD19 CAR-T,IM19,which is promising for further development and clinical investigation. | Zhitao Ying Ting He Shanzhao Jin Xiaopei Wang Wen Zheng Ningjing Lin Meifeng Tu Yan Xie Lingyan Ping Weiping Liu Lijuan Deng Yanping Ding Xuelian Hu Bing Bu Xin’an Lu Yuqin Song Jun Zhu | 2022 | Chinese Journal of Cancer Research2022,34,1: | 2 |
| 15 | Reactive Effect of Low Intensity He-Ne Laser upon Damaged Ultrastructure of Human Erythrocyte Membrane in Fenton System by Atomic Force Microscopy显示文摘发现 modulating 的机制有低紧张 He-Ne 激光行动的红血球的 deform 能力,我们在人的红血球的超微结构上学习了低紧张 He-Ne 激光的效果膜。红血球在暴露他们到低紧张 He-Ne 激光前从 aFenton 反应系统与自由激进分子一起被对待。损坏红血球膜的超微结构被原子力量显微镜学检验。结果证明红血球膜变得很不平,膜的表面上的分子在与自由激进分子一起对待以后集合了进不同大小尺寸的粒子。在非照耀的组和 He-Ne 激光比较分子的粒子的会众的度照耀( 9 mW 和 18 mW )组织,我们发现在激光的分子的粒子的平均尺寸照耀组在非照耀的组是比那小的,显示低紧张激光让了修理功能到红血球膜的损坏由自由激进分子生产了。 | Yanhong CU Zhouyi GUO Yanping ZHAO Ying ZHENG Yanfang QIAO Jiye CAI Songhao LIU | 2007 | Acta Biochimica et Biophysica Sinica2007,39,7: | 2 |
| 16 | Daylight and thermal performance of a switchable ethylene tetra-fluoro-ethylene cushion with dynamic control in different climates显示文摘Switchable multi-layer ethylene tetra-fluoro-ethylene(ETFE)cushion controls the natural light and heat flux passing through the cushion with varying outdoor conditions by dynamically modifying its properties.In this paper,the switchable ETFE cushions with ink printing of different optical and thermal properties were adopted as the window in a typical office model,and the indoor daylight and energy consumption were simulated by using Grasshopper software.Experimental model was built to validate the numerical model.Five locations representing five climate zones in China were selected to analyze the feasibility of the switchable ETFE cushion in different climates.The hourly indoor daylight and heat gain in a single day revealed the effects of the dynamic mechanism of ETFE cushion in improving indoor natural light and thermal environment.In addition,the annual daylight performance at the working area(1.5 m from the window)was simulated.ETFE cushion with printing of the lowest transmittance(ETFE1)was the optimal option for most cities and window-to-wall ratios,with the percentage of annual useful daylight hours up to 78.6%,except for the cases where the window-to-wall ratio(WWR)was 0.35 in Harbin,Beijing,and Hefei.The distribution of useful daylight hours revealed that ETFE cushions with low,medium,and high printing transmittance were suitable for offices where people work in the front,medium,and back region of the room,respectively.Energy consumption calculation revealed that ETFE1 showed advantages over other windows in most cities except for cities highly dominated by heating.ETFE1 delivered up to 33%of energy saving over a year in Kunming compared with the conventional double glazing but was not superior in cities with high heating and low cooling demands,such as Harbin. | Wanfang Zhao Wei He Zhongting Hu Xiaoyu Zheng Sheng Zhang Gaofei Xu Hongbing Chen Yanping Yuan | 2022 | Building Simulation2022,15,1: | 2 |
| 17 | Synthesis and Biological Evaluation of Amino Alcohol Containing 1,3,4-Oxadiazole显示文摘 | WU Yi ZHAO Yanping GUO Jing LV Haoze ZHENG Nan WANG Ensi | 2016 | Chemical Research in Chinese Universities2016,32,5: | 2 |
| 18 | Space Expression of Industry Status Using GIS and SWOT Analysis —Take the Planning Area in Lu'an as an Example显示文摘On the basis of sufficient understanding about the general situation of the Lu'an planning area, Anhui Province, this paper uses strengths weakness opportunity threats(SWOT) analysis to analyze the internal and external factors of the development of the planning area itself; then it analyzes the industrial cluster situation in the planning area, and uses GIS space analysis to analyze the industry status of the planning area, integrating it with the geographic space expression to provide references for formulating the economic development program of the Lu'an planning area. | WANG Hongchen LI Chang ZHENG Yanping | 2015 | Wuhan University Journal of Natural Sciences2015,20,5: | 1 |
| 19 | Effects of opening hole geometric parameters on hole-edge stress field of plates according to a complex variable function model显示文摘 | LI Cheng TIE Ying ZHENG Yanping | 2010 | Advanced Materials Research2010,97,: | 1 |
| 20 | A p53/CPEB2 negative feedback loop regulates renal cancer cell proliferation and migration显示文摘The tumor suppressor p53 transactivates the expression of multiple genes to exert its multifaceted functions and ultimately maintains genome stability.Thus,cancer cells develop various mechanisms to diminish p53 expression and bypass the cell cycle checkpoint.In this study,we identified the gene encoding RNAbinding protein cytoplasmic polyadenylation element-binding protein 2(CPEB2)as a p53 target.In turn,CPEB2 decreases p53 messenger RNA stability and translation to fine-tune p53 level.Specifically,we showed that CPEB2 binds the cytoplasmic polyadenylation elements in the p5330-untranslated region,and the RNA recognition motif and zinc finger(ZF)domains of CPEB2 are required for this binding.Furthermore,we found that CPEB2 was upregulated in renal cancer tissues and promotes the renal cancer cell proliferation and migration.The oncogenic effect of CPEB2 is partially dependent on negative feedback regulation of p53.Overall,we identify a novel regulatory feedback loop between p53 and CPEB2 and demonstrate that CPEB2 promotes tumor progression by inactivating p53,suggesting that CPEB2 is a potential therapeutic target in human renal cancer. | Jiehui Di Guang Zhao Hui Wang Yaoyao Wu Zhongjun Zhao Bao Zhu Yanping Zhang Junnian Zheng Yong Liu Ying Hu | 2021 | Journal of Genetics and Genomics2021,48,7: | 1 |