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| 1 | Distribution of heavy metals in sediments of the Pearl River Estuary,Southern China:Implications for sources and historical changes显示文摘The distribution of heavy metals(Pb,Zn,Cd and As) in sediments of the Pearl River Estuary was investigated.The spatial distribution of heavy metals displayed a decreasing pattern from the turbidity maxima to both upstream and downstream of the estuary,which suggested that suspended sediments played an important role in the trace metal distribution in the Pearl River Estuary.In addition,metal concentrations were higher in the west part of the estuary which received most of the pollutants from the Pearl River.In the sediment cores,fluxes of heavy metals were consistent with a predominant anthropogenic input in the period 1970-1990.From the mid-1990s to the 2000s,there was a significant decline in heavy metal pollution.The observed decline has shown the result of pollution control in the Pearl River Delta.However,it is noteworthy that the metal concentrations in the most recent sediment still remained considerably high.Taken together,the enrichment of heavy metals in sediments was largely controlled by anthropogenic pollution. | Feng Ye Xiaoping Huang Dawen Zhang Lei Tian Yanyi Zeng | 2012 | Journal of Environmental Sciences2012，24，4： | 18 |
| 2 | Combining sap flow measurement-based canopy stomatal conductance and ^(13)C discrimination to estimate forest carbon assimilation显示文摘The available methods for studying C uptake of forest and their problems in practices are reviewed, and a new approach to combining sap flow and 13C techniques is proposed in this paper. This approach, obtained through strict mathematic derivation, combines sap flow measure-ment-based canopy stomatal conductance and 13C discrimi-nation to estimate instantaneous carbon assimilation rate of a forest. Namely the mean canopy stomatal conductance (gc) acquired from accurate measurement of sap flux density is integrated with the relationship between 13C discrimination (?) and Ci/Ca (intercellular/ambient CO2 concentrations) and with that between Anet (net photosynthetic rate) and gCO2 (stomatal conductance for CO2) so that a new relation be-tween forest C uptake and ? as well as gc is established. It is a new method of such kind for studying the C exchange be-tween forest and atmosphere based on experimental ecology. | ZHAO Ping LU Ping MA Ling SUN Guchou RAO Xingquan CAI Xi'an ZENG Xiaoping | 2005 | Chinese Science Bulletin2005，50，18： | 9 |
| 3 | Newborn screening with targeted sequencing:a multicenter investigation and a pilot clinical study in China显示文摘Different newborn screening(NBS) programs have been practiced in many countries since the 1960 s. It is of considerable interest whether next-generation sequencing is applicable in NBS. We have developed a panel of 465 causative genes for 596 early-onset, relatively high incidence, and potentially actionable severe inherited diseases in our Newborn Screening with Targeted Sequencing(NESTS) program to screen 11,484 babies in 8 Women and Children’s hospitals nationwide in China retrospectively. The positive rate from preliminary screening of NESTS was 7.85%(902/11,484). With 45.89%(414/902) follow-up of preliminary positive cases, the overall clinically confirmative diagnosis rate of monogenic disorders was 12.07%(50/414), estimating an average of 0.95%(7.85% × 12.07%) clinical diagnosis rate, suggesting that monogenic disorders account for a considerable proportion of birth defects. The disease/gene spectrum varied in different regions of China. NESTS was implemented in a hospital by screening 3923 newborns to evaluate its clinical application. The turn-around time of a primary report, including the sequencing period of < 7 days, was within 11 days by our automatic interpretation pipeline. Our results suggest that NESTS is feasible and cost-effective as a first-tier NBS program, which will change the status of current clinical practice of NBS in China. | Chanjuan Hao Ruolan Guo Xuyun Hu Zhan Qi Qi Guo Xuanshi Liu Yuanhu Liu Yanhua Sun Xiaofen Zhang Feng Jin Xiujie Wu Ren Cai Dingyuan Zeng Xijiang Hu Xiaohua Wang Xiaoping Ji Wenjie Li Quansheng Xing Lanfang Mu Xiulian Jiang Xue Yang Weimin Yang Yan Zhang Qianli Yin Xin Ni Wei Li | 2022 | Journal of Genetics and Genomics2022，49，1： | 7 |
| 4 | Edge biomarkers for classification and prediction of phenotypes显示文摘In general,a disease manifests not from malfunction of individual molecules but from failure of the relevant system or network,which can be considered as a set of interactions or edges among molecules.Thus,instead of individual molecules,networks or edges are stable forms to reliably characterize complex diseases.This paper reviews both traditional node biomarkers and edge biomarkers,which have been newly proposed.These biomarkers are classified in terms of their contained information.In particular,we show that edge and network biomarkers provide novel ways of stably and reliably diagnosing the disease state of a sample.First,we categorize the biomarkers based on the information used in the learning and prediction steps.We then briefly introduce conventional node biomarkers,or molecular biomarkers without network information,and their computational approaches.The main focus of this paper is edge and network biomarkers,which exploit network information to improve the accuracy of diagnosis and prognosis.Moreover,by extracting both network and dynamic information from the data,we can develop dynamical network and edge biomarkers.These biomarkers not only diagnose the immediate pre-disease state but also detect the critical molecules or networks by which the biological system progresses from the healthy to the disease state.The identified critical molecules can be used as drug targets,and the critical state indicates the critical point of disease control.The paper also discusses representative biomarker-based methods. | ZENG Tao ZHANG WanWei YU XiangTian LIU XiaoPing LI MeiYi LIU Rui CHEN LuoNan | 2014 | Science China(Life Sciences)2014，57，11： | 5 |
| 5 | TiO_2-coated SnO_2 hollow spheres as anode materials for lithium ion batteries显示文摘TiO2-coated SnO2(TCS) hollow spheres,which are new anode materials for lithium ion(Li-ion) batteries,were prepared and characterized with X-ray diffraction(XRD) ,scanning electron microscopy(SEM) ,transmission electron microscopy(TEM) ,cyclic voltammetry(CV) ,and galvanostatic charge/discharge tests.The results obtained from XRD,SEM,and TEM show that TiO2 can be uniformly coated on the surface of SnO2 hollow spheres with the assistance of anionic surfactant.The cyclic voltammograms indicate that both TiO2 and SnO2 ex-hibit the activity for Li-ion storage.The charge/discharge tests show that the prepared TCS hollow spheres have a higher reversible coulomb efficiency and a better cycling stability than the uncoated SnO2 hollow spheres. | YI Jin LI Xiaoping HU Shejun LI Weishan ZENG Ronghua FU Zhao CHEN Lang | 2011 | Rare Metals2011，30，6： | 4 |
| 6 | Cumene Liquid Oxidation to Cumene Hydroperoxide over CuO Nanoparticle with Molecular Oxygen under Mild Condition显示文摘CuO nanoparticle 经由湿化学方法被综合并且被 X 光检查描绘衍射(XRD ) ,氮吸附解吸附作用,和扫描电子显微镜学(SEM ) 。有分子的氧的 cumene 的催化氧化在 CuO nanoparticle 上被学习。催化剂作为与常规方法, CuO/Al2O3,或同类的铜催化剂在可比较的反应条件下面准备的 CuO 相比显示出显著地更高的活动。用在为 7 h 的 358 K 的 0.25 g CuO nanoparticle 催化剂和 0.1 摩尔 cumene 的 cumene 变换, cumene 水疗院过氧化物(CHP ) 收益,和选择分别地是 44.2% , 41.2% 和 93.2% 。催化剂能被再循环。在 6 个再循环的实验以后,催化活动的损失都没被观察。 | Meiying Zhang Lefu Wang Hongbing Ji Bing Wu Xiaoping Zeng | 2007 | Journal of Natural Gas Chemistry2007，16，4： | 4 |
| 7 | Karyotype Analysis of Gazania rigens Varieties显示文摘For studying species origin, systematic evolution and phylogenetic relationship of Gazania rigens, four different G. rigens varieties, with different flower colors, were subjected to chromosome karyotype analysis. The somatic chromosome number in three varieties ‘Hongwen', ‘Xingbai'and ‘Richu' was 2n = 10, while in ‘Zhongguo Xunzhangju' it was 2n = 20. We speculate that the cardinal number of chromosomes in G. rigens plants is x = 5, in which case ‘Zhongguo Xunzhangju' is a tetraploid. The karyotype formulae of ‘Hongwen', ‘Xingbai' and ‘Richu' were 2n = 8m + 2sm,2n = 8m + 2sm and 2n = 10 m respectively. The karyotype formula of ‘Zhongguo Xunzhangju' was 2n = 18 m + 2sm. The asymmetrical karyotype coefficients of the four G. rigens varieties ranged from 53.80% to 58.84%. Only ‘Richu' had a ‘1A' karyotype, while the others were relatively symmetric ‘2A'. Karyotype analysis indicates that the three introduced varieties have a close genetic relationship. | ZENG Jiashi WANG Dongxu WU Yangqing GUO Xiaoyu ZHANG Yazhou LU Xiaoping | 2016 | Horticultural Plant Journal2016，2，5： | 3 |
| 8 | Characteristics of SARS-CoV-2 Delta variant-infected individuals with intermittently positive retest viral RNA after discharge显示文摘SARS-CoV-2-infected patients will be discharged when viral ribonucleic acid(RNA)is consecutively negative at least twice over a 24-h interval.However,we have demonstrated that positive retest viral RNA,a particular clinical phenomenon initially observed in discharged SARS-CoV-2-infected patients in early 2020[1,2],is the occasional reoccurrence of Polymerase Chain Reaction(PCR)-detectable viral RNA but not reinfection[3]. | Lu Li Jingyan Tang Zhiwei Xie Qingxin Gan Guofang Tang Zhongwei Hu Huimin Zeng Jingrong Shi Jiaojiao Li Yan Li Changwen Ke Min Kang Dan Liang Huan Lu Yuwei Tong Xilong Deng Jinxin Liu Hongzhou Lu Fuxiang Wang Fengyu Hu Feng Li Nanshan Zhong Xiaoping Tang | 2022 | National Science Review2022，9，10： | 3 |
| 9 | Conserved and differentiated functions of CIK receptor kinases in modulating stem cell signaling in Arabidopsis显示文摘The shoot apical meristem(SAM)and root apical meristem(RAM)act as pools of stem cells that give rise to aboveground and underground tissues and organs in higher plants,respectively.The CLAVATA3(CLV3)-WUSCHEL(WUS)negative-feedback loop acts as a core pathway controlling SAM homeostasis,while CLV3/EMBRYO SURROUNDING REGION(ESR)40(CLE40)and WUSCHEL-RELATED HOMEOBOX5(WOX5),homologs of CLV3 and WUS,direct columella stem cell fate.Moreover,CLV3 INSENSITIVE KINASES(CIKs)have been shown to be essential for maintaining SAM homeostasis,whereas whether they regulate the distal root meristem remains to be elucidated.Here,we report that CIKs are indispensable for transducing the CLE40 signal to maintain homeostasis of the distal root meristem.We found that the cik mutant roots displayed disrupted quiescent center and delayed columella stem cell(CSC)differentiation.Biochemical assays demonstrated that CIKs interact with ARABIDOPSIS CRINKLY4(ACR4)in a ligand-independent manner and can be phosphorylated by ACR4 in vitro.In addition,the phosphorylation of CIKs can be rapidly induced by CLE40,which partially depends on ACR4.Although CIKs act as conserved and redundant regulators in the SAM and RAM,our results demonstrated that they exhibit differentiated functions in these meristems. | Yafen Zhu Chong Hu Yanwei Cui Li Zeng Sunjingnan Li Mingsong Zhu Fanhui Meng Shuting Huang Li Long Jing Yi Jia Li Xiaoping Gou | 2021 | Molecular Plant2021，14，7： | 2 |
| 10 | Interaction of hsa-miR-381 and glioma suppressor LRRC4 is involved in glioma growth显示文摘 | Hailin Tang Xiaoping Liu Zeyou Wang Xiaoling She Xi Zeng Min Deng Qianjin Liao Xiaofang Guo Rong Wang Xiaoling Li Fang Zeng Minghua Wu Guiyuan Li | 2011 | Brain Research2011，，： | 1 |
| 11 | Research of multi- population agent genetic algorithm for feature selection显示文摘 | Li Yongming Zhang Sujuan Zeng Xiaoping | 2009 | Expert Systems with Applications2009，36，： | 1 |
| 12 | Controlling the lateral and vertical dimensions of Bi2Se3 nanoplates via seeded growth显示文摘nanostructures 的形态学的调整经常是一项令人满意却挑战性的任务。我们采用了播种生长方法并且导致了运动控制综合双性人 < 潜水艇 class= “ a-plus-plus ” > 2 Se < 潜水艇 class= “ a-plus-plus ” > 有可修改的形态学的 3 nanoplates。由操作先锋答案与注射泵在被注入种子答案的率,二个特殊生长模式能被认识到。与快注射,双性人的厚度<潜水艇class=“ a-plus-plus ”> 2 Se <潜水艇class=“ a-plus-plus ”>当边长度从 160 nm (种子)长大了到 12 m 时, 3 nanoplates 稍微从 7.5 nm (种子)增加了到 9.5 nm ,在播种生长的 6 个连续回合以后。与慢注射,厚度和边长度分别地在 6 轮生长以后同时增加了到 35 nm 和 6 m。这二个模式能被看作在原子免职和表面移植之间的一场比赛。产品出现了有趣,厚度依赖者拉曼性质。另外, NIR 透明,高度传导性、灵活的双性人<潜水艇class=“ a-plus-plus ”> 2 Se <潜水艇class=“ a-plus-plus ”> 3 有不同厚度的薄电影被同样综合的双性人的集会构造<潜水艇class=“ a-plus-plus ”> 2 Se <潜水艇class=“ a-plus-plus ”> 3 nanoplates 。这条途径能显著地与多样的形态学基于播种生长和运动控制支持万用的 nanostructures 的发展。 | Awei Zhuang Yuzhou Zhao Xianli Liu Mingrui Xu Youcheng Wang Unyong Jeong Xiaoping Wang Jie Zeng | 2015 | Nano Research2015，8，1： | 1 |
| 13 | Safety and Effectiveness of SA58 Nasal Spray Against COVID-19 Infection in Medical Personnel:An Open-Label,Blank-Controlled Study—Hohhot City,Inner Mongolia Autonomous Region,China,2022显示文摘Summary What is already known about this topic?The active ingredient of the SA58 Nasal Spray is a broad-spectrum neutralizing antibody with a high neutralizing capacity against different Omicron subvariants in vitro studies.What is added by this report?This study demonstrated the safety and effectiveness of SA58 Nasal Spray against coronavirus disease 2019(COVID-19)infection in medical personnel for the first time.What are the implications for public health practice?This study provides an effective approach for the public to reduce their risk of COVID-19 infection.The findings of this research have the potential to significantly reduce the risk of infection and limit human-to-human transmission in the event of a COVID-19 outbreak. | Shujie Si Canrui Jin Jianping Li Yunlong Cao Biao Kan Feng Xue Xiaoliang Sunney Xie Liang Fang Gang Zeng Shuo Zhang Yaling Hu Xiaoping Dong | 2023 | China CDC weekly2023，5，10： | 1 |
| 14 | Re- search of multi-population agent genetic algorithm for feature selec- tion 显示文摘 | LI Yongming ZHANG Sujuan ZENG Xiaoping | 2009 | Expert Systems with Applications2009，36，7： | 1 |
| 15 | Achieving cooperation in multiparty alliances:A social dilemma approach to partnership management 显示文摘 | Ming Zeng Xiaoping Chen | 2003 | Academy of Management Review2003，28，4： | 1 |
| 16 | Blind source separation based on high-resolution time–frequency distributions显示文摘 | Jing Guo Xiaoping Zeng Zhishun She | 2011 | Computers and Electrical Engineering2011，，1： | 1 |
| 17 | Detecting andBlocking P2P Botnets Through Contact Tracing Chains显示文摘 | Huang Zhiyong Zeng Xiaoping Liu Yong | 2010 | International Journal of Internet Protocol Technology2010，5，12： | 1 |
| 18 | A functional polymorphism at miR-491-5p binding site in the 3′-UTR of MMP-9 gene confers increased risk for atherosclerotic cerebral infarction in a Chinese population显示文摘 | Mei Yuan Qiong Zhan Xiaomei Duan Bingxin Song Sian Zeng Xiaoping Chen Qidong Yang Jian Xia | 2012 | Atherosclerosis2012，，： | 1 |
| 19 | A new strategy for urinary sediment segmentation based on wavelet,morphology and combination method显示文摘 | Li Yongming Zeng Xiaoping | 2006 | Computer Methods and Programs in Biomedicine2006，7，： | 1 |
| 20 | Spectrum Allocation for Cognitive Radio Networks with Non-Deterministic Bandwidth of Spectrum Hole显示文摘The spectrum allocation for cognitive radio networks(CRNs) has received considerable studies under the assumption that the bandwidth of spectrum holes is static. However, in practice, the bandwidth of spectrum holes is time-varied due to primary user/secondary user(PU/SU) activity and mobility, which result in non-determinacy. This paper studies the spectrum allocation for CRNs with non-deterministic bandwidth of spectrum holes. We present a novel probability density function(PDF) through order statistics as well as its simplified form to describe the statistical properties of spectrum holes, with which a statistical spectrum allocation model based on stochastic multiple knapsack problem(MKP) is formulated for spectrum allocation with non-deterministic bandwidth of spectrum holes. To reduce the computational complexity, we transform this stochastic programming problem into a constant MKP through exploiting the properties of cumulative distribution function(CDF), which can be solved via MTHG algorithm by using auxiliary variables. Simulation results illustrate that the proposed statistical spectrum allocation algorithm can achieve better performance compared with the existing algorithms when the bandwidth of spectrum holes is time-varied. | Jie Huang Xiaoping Zeng Xiaoheng Tan Xin Jian Yuan He | 2017 | China Communications2017，14，3： | 1 |
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