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| 1 | Wheel/rail dynamic interaction due to excitation of rail corrugation in high-speed railway显示文摘Characteristics of wheel-rail dynamic interaction due to the rail corrugation in a high-speed railway are analyzed based on the theory of vehicle-track coupled dynamics in this paper.Influences of the corrugation wavelength and depth on the wheel-rail dynamic performance are investigated.The results show that,under the excitation of a measured rail corrugation,the wheel-rail dynamic interaction of high-speed railway is enhanced obviously,and the high-frequency dynamic force between wheel and rail is generated,which has an obvious impact on the vibrations of the wheelset and rail,and little effect on the vibration of the frame and carbody.If the corrugation wavelength is shorter than the sensitive wavelength,the wheel-rail vertical force will increase with the growth of the corrugation wavelength,otherwise,it will decrease.However,the wheel-rail vertical force keeps increasing with the growth of corrugation depth.Furthermore,if the corrugation wavelength is shorter than the sensitive wavelength,the wheel-rail vertical force will increase with the decrease of the running speed,otherwise,it will decrease.It is also found that the critical wavelength of corrugation increases with the growth of the corrugation depth and the running speed,and the critical depth of corrugation is nonlinearly related to the sensitive wavelength. | WANG Kai Yun LIU Peng Fei ZHAI Wan Ming HUANG Chao CHEN Zai Gang GAO JianMin | 2015 | Science China(Technological Sciences)2015，58，2： | 17 |
| 2 | Blue Light-Triggered Chemical Reactions Underlie Phosphate Deficiency-Induced Inhibition of Root Elongation oM/ab/dops/s Seedlings Grown in Petri Dishes显示文摘To tolerate phosphate(Pi)deficiency in the environment,plants alter their developmental and metabolic programs.In the past two decades,researchers have extensively used Petri dish-grown seedlings of the model plant Arabidopsis thaliana to study the molecular mechanisms underlying root developmental responses to Pi deficiency.A typical developmental response of the Petri dish-grown Arabidopsis seedlings to Pi deficiency is the inhibited growth of primary root(PR).This response is generally thought to enhance the production of lateral roots and root hairs,which increases the plant’s ability to obtain Pi and is therefore regarded as an active cellular response.Here,we report that direct illumination of root surface with blue light is critical and sufficient for Pi deficiency-induced inhibition of PR growth in Arabidopsis seedlings.We further show that a blue light-triggered malate-mediated photo-Fenton reaction and a canonical Fenton reaction form an Fe redox cycle in the root apoplast.This Fe redox cycle results in the production of hydroxyl radicals that inhibit PR growth.In addition to revealing the molecular mechanism underlying Pi deficiency-induced inhibition of PR growth,our work demonstrated that this developmental change is not an active cellular response;instead,it is a phenotype resulting from root growth in transparent Petri dishes.This finding is significant because illuminated,transparent Petri dishes have been routinely used to study Arabidopsis root responses to environmental changes. | Zai Zheng Zhen Wang Xiaoyue Wang Dong Liu | 2019 | Molecular Plant2019，12，11： | 12 |
| 3 | A novel colloidal gold immunochromatography assay strip for the diagnosis of schistosomiasis japonica in domestic animals显示文摘Background:Schistosomiasis remains a major public health concern in China and an epidemiological survey has revealed that schistosome-infected bovines and goats are the main transmission sources for the disease.Therefore,development of a sensitive technique for the diagnosis of schistosomiasis in domestic animals is necessary.Method:A novel colloidal gold immunochromatography assay(GICA)strip was developed for detecting Schistosoma japonicum in domestic animals.The colloidal gold was conjugated with recombinant streptococcal protein G(rSPG).As the test and control lines,the schistosome soluble egg antigen and rSPG,respectively,were blotted on nitrocellulose membrane.Results:The lowest detectable serum dilution was 1∶640 for schistosome-infected buffaloes.The cross-reaction rate of GICA was 14.29%with Paramphistomum sp.in buffaloes,16.67%with Haemonchus sp.in goats,and 33.33%with Orientobilharzia sp.in goats.These results were slightly lower and similar to those obtained through ELISA.Moreover,the strips for detecting S.japonicum in mice,rabbits,buffaloes,and goats showed high sensitivity(100.00%,100.00%,100.00%,and 100.00%,respectively)and specificity(100.00%,100.00%,94.23%,and 88.64%,respectively).And the sensitivity or specificity of the GICA strips did not present any significant differences after storage for 12 months at room temperature.When compared with ELISA,the GICA strips exhibited similar sensitivity and specificity in the diagnosis of schistosomiasis in mice,rabbits,buffaloes,and goats.Besides,only 5μl of serum are required for the test and the detection can be completed within 5 min.Conclusion:This study is the first to develop a GICA strip using gold-rSPG conjugate for the diagnosing of schistosomiasis in domestic animals,and preliminary results showed that the developed strip may be suitable for large-scale screening of schistosomiasis in endemic areas. | Rui Xu Jintao Feng Yang Hong Chao Lv Dengyun Zhao Jiaojiao Lin Ke Lu Hao Li Jinming Liu Xiaodan Cao Tao Wang Jinli Zai Zhaozhe Wang Bingguang Jia Qian Han Chuangang Zhu | 2017 | Infectious Diseases of Poverty2017，6，1： | 12 |
| 4 | Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer显示文摘Metastasis,the development of secondary malignant growths at a distance from a primary tumor,is the cause of death for 90%of cancer patients,but little is known about how metastatic cancer cells adapt to and colonize new tissue environments.Here,using clinical samples,patient-derived xenograft(PDX)samples,PDX cells,and primary/metastatic cell lines,we discovered that liver metastatic colorectal cancer(CRC)cells lose their colon-specific gene transcription program yet gain a liver-specific gene transcription program.We showed that this transcription reprogramming is driven by a reshaped epigenetic landscape of both typical enhancers and super-enhancers.Further,we identified that the liver-specific transcription factors FOXA2 and HNF1A can bind to the gained enhancers and activate the liver-specific gene transcription,thereby driving CRC liver metastasis.Importantly,similar transcription reprogramming can be observed in multiple cancer types.Our data suggest that reprogrammed tissue-specific transcription promotes metastasis and should be targeted therapeutically. | Shuaishuai Teng Yang Eric Li Ming Yang Rui Qi Yiming Huang Qianyu Wang Yanmei Zhang Shanwen Chen Shasha Li Kequan Lin Yang Cao Qunsheng Ji Qingyang Gu Yujing Cheng Zai Chang Wei Guo Pengyuan Wang Ivan Garcia-Bassets Zhi John Lu Dong Wang | 2020 | Cell Research2020，30，1： | 11 |
| 5 | Clinical correlates of common corneal neovascular diseases: a literature review显示文摘A large subset of corneal pathologies involves the formation of new vessels(neovascularization), leading to compromised visual acuity. This article aims to review the clinical causes and presentations of corneal neovascularization(CNV) by examining the mechanisms behind common CNV-related corneal pathologies, with a particular focus on herpes simplex stromal keratitis,contact lenses-induced keratitis and CNV secondary to keratoplasty. Moreover, we reviewed CNV in the context of different types of corneal transplantation and keratoprosthesis, and summarized the most relevant treatment available so far. | Nizar Saleh Abdelfattah Mohamed Amgad Amira A Zayed Hamdy Salem Ahmed E Elkhanany Heba Hussein Nawal Abd El-Baky | 2015 | International Journal of Ophthalmology(English edition)2015，8，1： | 10 |
| 6 | Icariin Improves Cognitive Impairment after Traumatic Brain Injury by Enhancing Hippocampal Acetylation显示文摘Objective: To examine the effect of icariin(ICA) on the cognitive impairment induced by traumatic brain injury(TBI) in mice and the underlying mechanisms related to changes in hippocampal acetylation level. Methods: The modified free-fall method was used to establish the TBI mouse model. Mice with post-TBI cognitive impairment were randomly divided into 3 groups using the randomised block method(n=7): TBI(vehicle-treated), low-dose(75 mg/kg) and high-dose(150 mg/kg) of ICA groups. An additional sham-operated group(vehicle-treated) was employed. The vehicle or ICA was administrated by gavage for 28 consecutive days. The Morris water maze(MWM) test was conducted. Acetylcholine(ACh) content, m RNA and protein levels of choline acetyltransferase(Ch AT), and protein levels of acetylated H3(Ac-H3) and Ac-H4 were detected in the hippocampus. Results: Compared with the sham-operated group, the MWM performance, hippocampal ACh content, m RNA and protein levels of Ch AT, and protein levels of Ac-H3 and Ac-H4 were significantly decreased in the TBI group(P<0.05). High-dose of ICA significantly ameliorated the TBI-induced weak MWM performance, increased hippocampal ACh content, and m RNA and protein levels of Ch AT, as well as Ac-H3 protein level compared with the TBI group(P<0.05). Conclusion: ICA improved post-TBI cognitive impairment in mice by enhancing hippocampal acetylation, which improved hippocampal cholinergic function and ultimately improved cognition. | ZHANG Zi-gang WANG Xin ZAI Jin-hai SUN Cai-hua YAN Bing-chun | 2018 | Chinese Journal of Integrative Medicine2018，24，5： | 9 |
| 7 | TiO2 coated urchin-like SnO2 microspheres for efficient dye-sensitized solar cells显示文摘 | Amit Thapa Jiantao Zai Hytham Elbohy Prashant Poudel Nirmal Adhikari Xuefeng Qian Qiquan Qiao | 2014 | Nano Research2014，7，8： | 7 |
| 8 | Semiparametric Quantile Modelling of Hierarchical Data显示文摘 | Mao Zai TIAN Man Lai TANG Ping Shing CHAN | 2009 | Acta Mathematica Sinica,English Series2009，25，4： | 7 |
| 9 | Oxidation Modification of Polyacrylonitrile-Based Carbon Fiber and Its Electro-Chemical Performance as Marine Electrode for Electric Field Test显示文摘A novel sensor for ocean electric field testing has been fabricated by polyacrylonitrile-based on carbon fibers with electro-chemical oxidation.The surface profile characteristics of the carbon fibers were characterized by scanning electron microscope,Fourier transform infrared spectra and contact angle.Cyclic voltammetry and Tafel curves have been used to study its electro-chemical performances.Two identical electrodes in sea water as the electric field sensor will swiftly respond to applied electric field which causes positive and negative ions to move in opposite direction,resulting in a electric potential difference(ΔE).Test result indicates that the offset potential is typically below 1 m V with a drift of 60-170μVd^-1.Typical self noise level is 1.07 nV√Hz^(1/2)@1 Hz.The electric field response indicates that the modified electrode pair shows better response to AC sine signal of amplitude and frequency(5 mV and 1 mHz)respectively than its blank.The electric field response model of the modified electrodes is creatively presented according to its electric double layer capacitance and Faraday pseudo-capacitance.Many advantages of the carbon fiber electric field electrode will make it have potential application prospect. | ZAI Xuerong LIU Ang TIAN Yuhua CHAI Fanggang FU Yubin | 2020 | Journal of Ocean University of China2020，19，2： | 7 |
| 10 | Formation of NiFe_2O_4/Expanded Graphite Nanocomposites with Superior Lithium Storage Properties显示文摘A Ni Fe_2O_4/expanded graphite(Ni Fe_2O_4/EG)nanocomposite was prepared via a simple and inexpensive synthesis method. Its lithium storage properties were studied with the goal of applying it as an anode in a lithium-ion battery. The obtained nanocomposite exhibited a good cycle performance, with a capacity of 601 m Ah g^(-1)at a current of 1 A g^(-1)after 800 cycles. This good performance may beattributed to the enhanced electrical conductivity and layered structure of the EG. Its high mechanical strength could postpone the disintegration of the nanocomposite structure,efficiently accommodate volume changes in the Ni Fe_2O_4-based anodes, and alleviate aggregation of Ni Fe_2O_4 nanoparticles. | Yinglin Xiao Jiantao Zai Bingbing Tian Xuefeng Qian | 2017 | Nano-Micro Letters2017，9，3： | 7 |
| 11 | Clinical features, endoscopic polypectomy and STK11 gene mutation in a nine-month-old Peutz-Jeghers syndrome Chinese infant显示文摘AIM: To investigate multiple polyps in a Chinese PeutzJeghers syndrome(PJS) infant. METHODS: A nine-month-old PJS infant was admitted to our hospital for recurrent prolapsed rectal polyps for one month. The clinical characteristics, a colonoscopic image, the pathological characteristics of the polyps and X-ray images of the intestinal perforation were obtained. Serine threonine-protein kinase 11(STK11) gene analysis was also performed using a DNA sample from this infant.RESULTS: Here we describe the youngest known Chinese infant with PJS. Five polyps, including a giant polyp of approximately 4 cm × 2 cm in size, were removed from the infant's intestine. Laparotomy was performed to repair a perforation caused by pneumoperitoneum. The pathological results showed that this child had PJS. Molecular analysis of the STK11 gene further revealed a novel frameshift mutation(c.64_65het_del AT) in exon 1 in this PJS infant.CONCLUSION: The appropriate treatment method for multiple polyps in an infant must be carefully considered. Our results also show that the STK11 gene mutation is the primary cause of PJS. | Zhi-Heng Huang Zai Song Ping Zhang Jie Wu Ying Huang | 2016 | World Journal of Gastroenterology2016，22，11： | 7 |
| 12 | PDK1 plays a critical role in regulating cardiac function in mice and human显示文摘背景 PDK1 是在哺乳动物的开发起一个关键作用的必要蛋白质 kinase。老鼠缺乏 PDK1 在 E9.5 导致多重畸形和胚胎的致命性。阐明在心的 PDK1 的角色,我们调查了在不同生长时期和在我们采用了的人的失败的 heart.Methods 发信号的 PDK1 的改变在心缺乏 PDK1 的鼠标的心脏的显型产生 PDK1flox/flox 的 Cre/loxP 系统:-MHC-Cre 老鼠,明确地在出生在心肌删除了 PDK1,和 tamoxifen 可诱导的心特定的 PDK1 猛烈老鼠(PDK1flox/flox : MerCreMer 老鼠) ,在哪个 PDK1 与 tamoxifen 响应处理在心肌层被删除。从人的失败的心和正常的心的 Transmural 心肌的纸巾从左室的顶被取样分析由西方的 blotting.Results PDK1flox/flox 表明小径的 PDK1/Akt 的活动:-MHC-Cre 老鼠在 5 和 10 个星期死于心失败旧。PDK1flox/flox-MerCreMer 老鼠在 8 个星期在 tamoxifen 处理的开始以后从 5 ~ 21 个星期死于心失败旧。我们在人的失败的心纸巾发现那个表达式 PDK1 的层次显著地与我们的结果建议的控制 hearts.Conclusion 相比被减少发信号的那 PDK1 网络参加在鼠标调整心脏的生存能力和功能,并且可以也涉及人的心失败疾病。 | DI Ruo-min FENG Qiu-ting CHANG Zai LUAN Qing ZHANG Yang-yang HUANG Jun LI Xin-li YANG Zhong-zhou | 2010 | Chinese Medical Journal2010，，17： | 7 |
| 13 | Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis显示文摘Lung injury and fibrosis represent the most significant outcomes of severe and acute lung disorders,including COVID-19.However,there are still no effective drugs to treat lung injury and fibrosis.In this study,we report the generation of clinical-grade human embryonic stem cells(hESCs)-derived immunity-and matrix-regulatory cells(IMRCs)produced under good manufacturing practice requirements,that can treat lung injury and fibrosis in vivo.We generate IMRCs by sequentially differentiating hESCs with serum-free reagents.IMRCs possess a unique gene expression profile distinct from that of umbilical cord mesenchymal stem cells(UCMSCs),such as higher expression levels of proliferative,immunomodulatory and anti-fibrotic genes.Moreover,intravenous delivery of IMRCs inhibits both pulmonary inflammation and fibrosis in mouse models of lung injury,and significantly improves the survival rate of the recipient mice in a dose-dependent manner,likely through paracrine regulatory mechanisms.IMRCs are superior to both primary UCMSCs and the FDA-approved drug pirfenidone,with an excellent efficacy and safety profile in mice and monkeys.In light of public health crises involving pneumonia,acute lung injury and acute respiratory distress syndrome,our findings suggest that IMRCs are ready for clinical trials on lung disorders. | Jun Wu Dingyun Song Zhongwen Li Baojie Guo Yani Xiao Wenjing Liu Lingmin Liang Chunjing Feng Tingting Gao Yanxia Chen Ying Li Zai Wang Jianyan Wen Shengnan Yang Peipei Liu Lei Wang Yukai Wang Liang Peng Glyn Nigel Stacey Zheng Hu Guihai Feng Wei Li Yan Huo Ronghua Jin Ng Shyh-Chang Qi Zhou Liu Wang Baoyang Hu Huaping Dai Jie Hao | 2020 | Cell Research2020，30，9： | 7 |
| 14 | Heterogeneously supported pseudo-single atom Pt as sustainable hydrosilylation catalyst显示文摘 | Huachao Zai Yizhou Zhao Shanyu Chen Lei Ge Changfeng Chen Qi Chen Yujing Li | 2018 | Nano Research2018，11，5： | 6 |
| 15 | Host immune cellular reactions in corneal neovascularization显示文摘Corneal neovascularization(CNV) is a global important cause of visual impairment. The immune mechanisms leading to corneal heme- and lymphangiogenesis have been extensively studied over the past years as more attempts were made to develop better prophylactic and therapeutic measures. This article aims to discuss immune cells of particular relevance to CNV, with a focus on macrophages, Th17 cells, dendritic cells and the underlying immunology of common pathologies involving neovascularization of the cornea. Hopefully, a thorough understanding of these topics would propel the efforts to halt the detrimental effects of CNV. | Nizar S.Abdelfattah Mohamed Amgad Amira A Zayed | 2016 | International Journal of Ophthalmology(English edition)2016，9，4： | 5 |
| 16 | CoFe_2O_4-Graphene Nanocomposites Synthesized through An Ultrasonic Method with Enhanced Performances as Anode Materials for Li-ion Batteries显示文摘Co Fe2O4-graphene nanosheets(Co Fe2O4-GNSs) were synthesized through an ultrasonic method, and their electrochemical performances as Li-ion battery electrode were improved by annealing processes. The nanocomposites obtained at 350 °C maintained a high specific capacity of 1,257 m Ah g-1even after 200 cycles at 0.1 A g-1. Furthermore,the obtained materials also have better rate capability, and it can be maintained to 696, 495, 308, and 254 m Ah g-1at 1, 2,5, and 10 A g-1, respectively. The enhancements realized in the reversible capacity and cyclic stability can be attributed to the good improvement in the electrical conductivity achieved by annealing at appropriate temperature, and the electrochemical nature of Co Fe2O4 and GNSs during discharge–charge processes. | Yinglin Xiao Xiaomin Li Jiantao Zai Kaixue Wang Yong Gong Bo Li Qianyan Han Xuefeng Qian | 2014 | Nano-Micro Letters2014，6，4： | 5 |
| 17 | High power and stable P-doped yolk-shell structured Si@C anode simultaneously enhancing conductivity and Li^(+)diffusion kinetics显示文摘Silicon is a low price and high capacity ancxje material for lithium-ion batteries.The yolk-shell structure can effectively accommodate Si expansion to improve stability.However,the limited rate performance of Si anodes can't meet people's growing demand for high power density.Herein,the phosphorus-doped yolk-shell Si@C materials(P-doped Si@C)were prepared through carbon coating on P-doped Si/SiO_(x)matrix to obtain high power and stable devices.Therefore,the as-prepared P-doped Si@C electrodes delivered a rapid increase in Coulombic efficiency from 74.4%to 99.6%after only 6 cycles,high capacity retention of-95%over 800 cycles at 4 A·g^(-1),and great rate capability(510 mAh·g^(-1)at 35 A·g^(-1)).As a result,P-doped Si@C anodes paired with commercial activated carbon and LiFePO_(4)cathode to assemble lithium-ion capacitor(high power density of〜61,080 W·kg^(-1)at 20 A·g^(-1))and lithium-ion full cell(good rate performance with 68.3 mAh·g^(-1)at 5 C),respectively.This work can provide an effective way tofurther improve power density and stability for energy storage devices. | Ming Chen Qinnan Zhou Jiantao Zai Asma Iqbal TsegayeTadesse Tsega Boxu Dong Xuejiao Liu Yuchi Zhang Changyu Yan Liang Zhao Ali Nazakat SharelPeisan E CheeTongJohn Low Xuefeng Qian | 2021 | Nano Research2021，14，4： | 5 |
| 18 | Multifractal characteristics of shale and tight sandstone pore structures with nitrogen adsorption and nuclear magnetic resonance显示文摘Based on the experiments of nitrogen gas adsorption(N_2 GA) and nuclear magnetic resonance(NMR),the multifractal characteristics of pore structures in shale and tight s andstone from the Chang 7 member of Trias sic Yanchang Formation in Ordos Basin,NW China,are investigated.The multifractal spectra obtained from N2 GA and NMR are analyzed with pore throat structure parameters.The results show that the pore size distributions obtained from N2 GA and NMR are different,and the obtained multifractal characteristics vary from each other.The specific surface and total pore volume obtained by N2 GA experiment have correlations with multifractal characteristics.For the core samples with the similar specific surface,the value of the deviation of multifractal spectra Rd increases with the increase in the proportion of large pores.When the proportion of macropores is small,the Rd value will increase with the increase in specific surface.The multifractal characteristics of pore structures are influenced by specific surface area,average pore size and adsorption volume measured from N2 GA experiment.The multifractal characteristic parameters of tight sandstone measured from NMR spectra are larger than those of shale,which may be caused by the differences in pore size distribution and porosity of shale and tight sandstone. | Fu-Yong Wang Kun Yang Yun Zai | 2020 | Petroleum Science2020，17，5： | 4 |
| 19 | Decreasing nitrogen assimilation under drought stress by suppressing DST-mediated activation of Nitrate Reductase 1.2 in rice显示文摘Nitrogen is an essential nutrient for plant growth and development,and plays vital roles in crop yield.Assimilation of nitrogen is thus fine-tuned in response to heterogeneous environments.However,the regulatory mechanism underlying this essential process remains largely unknown.Here,we report that a zinc-finger transcription factor,drought and salt tolerance(DST),controls nitrate assimilation in rice by regulating the expression of OsNR1.2.We found that loss of function of DSTresults in a significant decrease of nitrogen use efficiency(NUE)in the presence of nitrate.Furtherstudy revealed that DST is required for full nitrate reductase activity in rice and directly regulates the expression of OsNR1.2,a gene showing sequence similarity to nitrate reductase.Reverse genetics and biochemistry studies revealed that OsNR1.2 encodes an NADH-dependent nitrate reductase that is required for high NUE of rice.Interestingly,the DST-OsNR1.2 regulatory module is involved in the suppression of nitrate assimilation under drought stress,which contributes to drought tolerance.Considering the negative role of DST in stomata closure,as revealed previously,the positive role of DST in nitrogen assimilation suggests a mechanism couplingni-trogen metabolism and stomata movement.The discovery of this coupling mechanism will aid the engi-neering of drought-tolerant crops with high NUE in the future. | Mei-Ling Han Qiao-Yan Lv Jing Zhang Tao Wang Chao-Xing Zhang Ru-Jiao Tan Ya-Ling Wang Li-Yuan Zhong Yi-Qun Gao Zhen-Fei Chao Qian-Qian Li Gen-Yun Chen Zai Shi Hong-Xuan Lin Dai-Yin Chao | 2022 | Molecular Plant2022，15，1： | 4 |
| 20 | The LRXs-RALFs-FER module controls plant growth and salt stress responses by modulating multiple plant hormones显示文摘Salt stress is a major environmental factor limiting plant growth and productivity.We recently discovered an important new salt tolerance pathway,where the cell wall leucine-rich repeat extensins LRX3/4/5,the RAPID ALKALINIZATION FACTOR(RALF)peptides RALF22/23 and receptor-like kinase FERONIA(FER)function as a module to simultaneously regulate plant growth and salt stress tolerance.However,the intracellular signaling pathways that are regulated by the extracellular LRX3/4/5-RALF22/23-FER module to coordinate growth,cell wall integrity and salt stress responses are still unknown.Here,we report that the LRX3/4/5-RALF22/23-FER module negatively regulates the levels of jasmonic acid(JA),salicylic acid(SA)and abscisic acid(ABA).Blocking JA pathway rescues the dwarf phenotype of the lrx345 and fer-4mutants,while disruption of ABA biosynthesis suppresses the salt-hypersensitivity of these mutants.Many salt stress-responsive genes display abnormal expression patterns in the lrx345 and fer-4 mutants,as well as in the wild type plants treated with epigallocatechin gallate(EGCG),an inhibitor of pectin methylesterases,suggesting cell wall integrity as a critical factor that determines the expression pattern of stress-responsive genes.Production of reactive oxygen species(ROS)is constitutively increased in the lrx345 and fer-4mutants,and inhibition of ROS accumulation suppresses the salt-hypersensitivity of these mutants.Together,our work provides strong evidence that the LRX3/4/5-RALF22/23-FER module controls plant growth and salt stress responses by regulating hormonal homeostasis and ROS accumulation. | Chunzhao Zhao Wei Jiang Omar Zayed Xin Liu Kai Tang Wenfeng Nie Yali Li Shaojun Xie Yuan Li Tiandan Long Linlin Liu Yingfang Zhu Yang Zhao Jian-Kang Zhu | 2021 | National Science Review2021，8，1： | 3 |
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