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| 1 | Crack monitoring method based on Cu coating sensor and electrical potential technique for metal structure显示文摘Advanced crack monitoring technique is the cornerstone of aircraft structural health monitoring.To achieve real-time crack monitoring of aircraft metal structures in the course of service,a new crack monitoring method is proposed based on Cu coating sensor and electrical potential difference principle.Firstly,insulation treatment process was used to prepare a dielectric layer on structural substrate,such as an anodizing layer on 2A12-T4 aluminum alloy substrate,and then a Cu coating crack monitoring sensor was deposited on the structure fatigue critical parts by pulsed bias arc ion plating technology.Secondly,the damage consistency of the Cu coating sensor and2A12-T4 aluminum alloy substrate was investigated by static tensile experiment and fatigue test.The results show that strain values of the coating sensor and the 2A12-T4 aluminum alloy substrate measured by strain gauges are highly coincident in static tensile experiment and the sensor has excellent fatigue damage consistency with the substrate.Thirdly,the fatigue performance discrepancy between samples with the coating sensor and original samples was investigated.The result shows that there is no obvious negative influence on the fatigue performance of the 2A12-T4 aluminum alloy after preparing the Cu coating sensor on its surface.Finally,crack monitoring experiment was carried out with the Cu coating sensor.The experimental results indicate that the sensor is sensitive to crack,and crack origination and propagation can be monitored effectively through analyzing the change of electrical potential values of the coating sensor. | Hou Bo He Yuting Cui Ronghong Gao Chao Zhang Teng | 2015 | Chinese Journal of Aeronautics2015，28，3： | 10 |
| 2 | Confined van der Waals Epitaxial Growth of Two-Dimensional Large Single-Crystal In_(2)Se_(3) for Flexible Broadband Photodetectors显示文摘The controllable growth of two-dimensional(2D)semiconductors with large domain sizes and high quality is much needed in order to reduce the detrimental efect of grain boundaries on device performance but has proven to be challenging.Here,we analyze the precursor concentration on the substrate surface which signifcantly infuences nucleation density in a vapor deposition growth process and design a confned micro-reactor to grow 2D In_(2)Se_(3) with large domain sizes and high quality.Te uniqueness of this confned micro-reactor is that its size is∼102-103 times smaller than that of a conventional reactor.Such a remarkably small reactor causes a very low precursor concentration on the substrate surface,which reduces nucleation density and leads to the growth of 2D In_(2)Se_(3) grains with sizes larger than 200�m.Our experimental results show large domain sizes of the 2D In_(2)Se_(3) with high crystallinity.Te fexible broadband photodetectors based on the as-grown In_(2)Se_(3) show rise and decay times of 140 ms and 25 ms,efcient response(5.6 A/W),excellent detectivity(7×10^(10) Jones),high external quantum efciency(251%),good fexibility,and high stability.Tis study,in principle,provides an efective strategy for the controllable growth of high quality 2D materials with few grain boundaries. | Lei Tang Changjiu Teng Yuting Luo Usman Khan Haiyang Pan Zhengyang Cai Yue Zhao Bilu Liu Hui-Ming Cheng | 2019 | Research2019，，1： | 7 |
| 3 | Review on grid-forming converter control methods in high-proportion renewable energy power systems显示文摘Grid-forming(GFM)converters can provide inertia support for power grids through control technology,stabilize voltage and frequency,and improve system stability,unlike traditional grid-following(GFL)converters.Therefore,in future“double high”power systems,research on the control technology of GFM converters will become an urgent demand.In this paper,we first introduce the basic principle of GFM control and then present five currently used control strategies for GFM converters:droop control,power synchronization control(PSC),virtual synchronous machine control(VSM),direct power control(DPC),and virtual oscillator control(VOC).These five strategies can independently establish voltage phasors to provide inertia to the system.Among these,droop control is the most widely used strategy.PSC and VSM are strategies that simulate the mechanical characteristics of synchronous generators;thus,they are more accurate than droop control.DPC regulates the active power and reactive power directly,with no inner current controller,and VOC is a novel method under study using an oscillator circuit to realize synchronization.Finally,we highlight key technologies and research directions to be addressed in the future. | Yuting Teng Wei Deng Wei Pei Yifeng Li Li Ding Hua Ye | 2022 | Global Energy Interconnection2022，5，3： | 3 |
| 4 | Nutritional properties of Europen eel(Anguilla anguilla)bone peptide-calcium and its apoptosis effect on Caco-2 cells显示文摘The present study aimed at making a rational usage for European eel bone by-products by preparing Europen eel bone peptide chelated calcium(EBPC-Ca).Nutritional properties and bioactivity of EBPC-Ca were evaluated.Results showed that nutritional properties of calcium ions will cause intra-and inter-molecular folding and aggregation of peptide to uniformly form EBPC-Ca chelate.The chelated compound of EBPC and calcium ion triggered a strong apoptosis in heterogeneous human epithelial colorectal adenocarcinoma(Caco-2)in concentration-and time-dependent manners.Western blot analysis revealed that the EBPC-Ca induced apoptosis may be the result of a blocked autophagy flux through mitochondrial-dependent pathway.Additionally,the increase in FGF-23 protein expression inhibited the absorption of calcium ions and alleviated cell apoptosis.It was also found that the cell apoptosis occurs with significant increases in the levels of reactive oxygen species(ROS)and Ca^(2+)in the cells,indicating the anti-tumor potential of EBPC-Ca may involve multiple channels. | Hui Teng Yuewei Qian Xiaoyun Fan Hui Cao Yuting Tian Lei Chen | 2022 | Food Science and Human Wellness2022，11，6： | 3 |
| 5 | Corrosion and aging of organic aviation coatings:A review显示文摘Organic anticorrosive aviation coatings are an effective guarantee for aviation structure,since aircraft corrosion can lead to great economic losses.Whether it is during ground parking or air cruises,organic aviation coatings are important barriers to the corrosion of aviation structure.With the vigorous development of the aviation industry,organic aviation coatings continue to meet the challenges of diverse,complex,and harsh service environments.This review analyzes and summarizes the research status of the types and development of organic aviation coatings,influencing factors and mechanisms,experimental methods,calendar life research methods,and modification methods.It also summarizes the research results that have been achieved to date.The current research deficiencies in the equivalence relationship between atmospheric exposure and artificial acceleration,failure criteria and life prediction were pointed out,and nano-modification technology,and future research strategies and directions that need breakthroughs are discussed. | Tianyu ZHANG Teng ZHANG Yuting HE Yuchen WANG Yaping BI | 2023 | Chinese Journal of Aeronautics2023，36，4： | 2 |
| 6 | Climate technology transfer in BRI era:needs,priorities,and barriers from receivers’perspective显示文摘Technology is an instrument to build BRI relationships,mitigate the environmental and climate impacts of BRI projects,as well as to enhance environmental sustainability in the regions.This study aims to reposition China in global climate technology transfer in BRI era and to obtain initial knowledge on needs,priorities,and barriers from the receivers’perspective.Focus group method with aid of questionnaire survey and follow-up face-to-face interviews was adopted to capture the major issues directly expressed by receivers from these countries.A total of 63 valid questionnaires were collected,and 13 respondents were face-to-face interviewed.The results confirmed that energy and agriculture were the most prioritized sectors for mitigation and adaptation in the developing countries alongside OBOR.The prioritized technologies for mitigation included cogeneration,solar photovoltaic,and biomass/biogas electricity.Irrigation,conservation agriculture,and soil management were prioritized for adaptation in agricultural sector,and water recycling and reuse,source water protection,and urban drainage management in water resource sector.Technology cost during installation and operation was stressed as the most important factor constraining the application and diffusion of climate technologies.But communication including language,information,and ways of communication,was also identified as an important factor.This implied that the conventional climate technology transfer need adapt to changing contexts of BRI and be complemented with innovative approaches involving multi-actors in different phases of climate technology development.Due to the limited representativeness of the sample,the results can hardly be generalized to all the countries,but raised interesting topics for future researches. | Minpeng Chen Lei Zhang Fei Teng Jingjing Dai Zhuang Li Ziqi Wang Yuting Li | 2020 | Ecosystem Health and Sustainability2020，6，1： | 1 |
| 7 | Numerical Analysis of Static Performance Comparison of Friction Stir Welded versus Riveted 2024-T3 Aluminum Alloy Stiffened Panels显示文摘Most researches on the static performance of stiffened panel joined by friction stir welding(FSW) mainly focus on the compression stability rather than shear stability. To evaluate the potential of FSW as a replacement for traditional rivet fastening for stiffened panel assembly in aviation application, finite element method(FEM) is applied to compare compression and shear stability performances of FSW stiffened panels with stability performances of riveted stiffened panels. FEMs of 2024-T3 aluminum alloy FSW and riveted stiffened panels are developed and nonlinear static analysis method is applied to obtain buckling pattern, buckling load and load carrying capability of each panel model. The accuracy of each FEM of FSW stiffened panel is evaluated by stability experiment of FSW stiffened panel specimens with identical geometry and boundary condition and the accuracy of each FEM of riveted stiffened panel is evaluated by semi-empirical calculation formulas. It is found that FEMs without considering weld-induced initial imperfections notably overestimate the static strengths of FSW stiffened panels. FEM results show that, buckling patterns of both FSW and riveted compression stiffened panels represent local buckling of plate between stiffeners. The initial buckling waves of FSW stiffened panel emerge uniformly in each plate between stiffeners while those of riveted panel mainly emerge in the mid-plate. Buckling patterns of both FSW and riveted shear stiffened panels represent local buckling of plate close to the loading corner. FEM results indicate that, shear buckling of FSW stiffened panel is less sensitive to the initial imperfections than compression buckling. Load carrying capability of FSW stiffened panel is less sensitive to the initial imperfections than initial buckling. It can be concluded that buckling loads of FSW panels are a bit lower than those of riveted panels whereas carrying capabilities of FSW panels are almost equivalent to those of riveted panels with identical geometries. Finite element method for simulating static performances of FSW and riveted stiffened panels is proposed and evaluated and some beneficial conclusions are obtained, which offer useful references for analysis and application of FSW to replace rivet fastening in aviation stiffened panel assembly. | SHAO Qing HE Yuting ZHANG Teng WU Liming | 2014 | Chinese Journal of Mechanical Engineering2014，27，4： | 0 |
| 8 | Cyasterone inhibits IL-1β-mediated apoptosis and inflammation via the NF-κB and MAPK signaling pathways in rat chondrocytes and ameliorates osteoarthritis in vivo显示文摘Osteoarthritis is a prevalent global joint disease,which is characterized by inflammatory reaction and cartilage degradation.Cyasterone,a sterone derived from the roots of Cyathula officinalis Kuan,exerts protective effect against several inflammationrelated diseases.However,its effect on osteoarthritis remains unclear.The current study was designed to investigate the potential antiosteoarthritis activity of cyasterone.Primary chondrocytes isolated from rats induced by interleukin(IL)-1βand a rat model stimulated by monosodium iodoacetate(MIA)were used for in vitro and in vivo experiments,respectively.The results of in vitro experiments showed that cyasterone apparently counteracted chondrocyte apoptosis,increased the expression of collagen II and aggrecan,and restrained the production of the inflammatory factors inducible nitric oxide synthase(iNOS),cyclooxygenase-2(COX-2),a disintegrin and metalloproteinase with thrombospondin motifs-5(ADAMTS-5),metalloproteinase-3(MMP-3),and metalloproteinase-13(MMP13)induced by IL-1βin chondrocytes.Furthermore,cyasterone ameliorated the inflammation and degenerative progression of osteoarthritis potentially by regulating the nuclear factor kappa B(NF-κB)and mitogen-activated protein kinase(MAPK)pathways.For in vivo experiments,cyasterone significantly alleviated the inflammatory response and cartilage destruction of rats induced by monosodium iodoacetate,where dexamethasone was used as the positive control.Overall,this study laid a theoretical foundation for developing cyasterone as an effective agent for the alleviation of osteoarthritis. | TENG Li SHEN Yue QU Yuhan YANG Longfei YANG Yuting JIAN Xi FAN Shengli ZHANG Lele FU Qiang | 2023 | Chinese Journal of Natural Medicines2023，21，2： | 0 |
| 9 | Modified poly(methyl methacrylate) bone cement in the treatment of Kümmell disease显示文摘Kuümmell disease(KD)causes serious vertebral body collapse in patients.However,only a few case reports have been conducted and the number of patients with KD investigated was limited.Additionally,the frequently used poly(methyl methacrylate)(PMMA)bone cement for KD is limited by excessive modulus and poor biocompatibility.Herein,we aimed to modify PMMA bone cement with mineralized collagen(MC),and compare the clinical effects,image performance and finite ele-ment analysis between the modified bone cement and PMMA bone cement for the treatment of phase I and II KD.Thirty-nine KD patients treated with PMMA bone cement and 40 KD patients treated with MC-modified PMMA bone cement from June 2015 to March 2017 were retrospectively analyzed.The surgical procedure,intraoperative blood loss,hospital stay and complications were compared between different groups.Visual analog scale,Oswestry disability index,anterior verte-bral height,posterior vertebral height,computed tomography value,adjacent vertebral re-fracture,Cobb angle and wedge-shaped correction angle were evaluated.Additionally,the representative sample was selected for finite element analysis.We found that the MC-modified PMMA bone ce-ment could achieve the same effect as that of PMMA bone cement and was associated with better vertebral height restoration in the long term. | Jinjin Zhu Shuhui Yang Yute Yang Teng Yao Gang Liu Shunwu Fan He Zhao Fuzhai Cui Xiumei Wang Guoqiang Jiang Xiangqian Fang | 2021 | Regenerative Biomaterials2021，8，1： | 0 |
| 10 | mRNA-based therapeutics:powerful and versatile tools to combat diseases显示文摘The therapeutic use of messenger RNA(mRNA)has fueled great hope to combat a wide range of incurable diseases.Recent rapid advances in biotechnology and molecular medicine have enabled the production of almost any functional protein/peptide in the human body by introducing mRNA as a vaccine or therapeutic agent.This represents a rising precision medicine field with great promise for preventing and treating many intractable or genetic diseases.In addition,in vitro transcribed mRNA has achieved programmed production,which is more effective,faster in design and production,as well as more flexible and cost-effective than conventional approaches that may offer.Based on these extraordinary advantages,mRNA vaccines have the characteristics of the swiftest response to large-scale outbreaks of infectious diseases,such as the currently devastating pandemic COVID-19.It has always been the scientists’desire to improve the stability,immunogenicity,translation efficiency,and delivery system to achieve efficient and safe delivery of mRNA.Excitingly,these scientific dreams have gradually been realized with the rapid,amazing achievements of molecular biology,RNA technology,vaccinology,and nanotechnology.In this review,we comprehensively describe mRNA-based therapeutics,including their principles,manufacture,application,effects,and shortcomings.We also highlight the importance of mRNA optimization and delivery systems in successful mRNA therapeutics and discuss the key challenges and opportunities in developing these tools into powerful and versatile tools to combat many genetic,infectious,cancer,and other refractory diseases. | Shugang Qin Xiaoshan Tang Yuting Chen Kepan Chen Na Fan Wen Xiao Qian Zheng Guohong Li Yuqing Teng Min Wu Xiangrong Song | 2022 | Signal Transduction and Targeted Therapy2022，7，6： | 0 |
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